Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514792![]() (CHEMBL4519240) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of ssRNA06-induced NF-kappaB activation measured after 24 hrs by quanti-b... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514792![]() (CHEMBL4519240) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514809![]() (CHEMBL4530243) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514806![]() (CHEMBL4452260) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514804![]() (CHEMBL4461378) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514797![]() (CHEMBL4451165) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514805![]() (CHEMBL4539893) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514813![]() (CHEMBL4471285) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514807![]() (CHEMBL4590994) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 390 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514796![]() (CHEMBL4535822) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 390 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514818![]() (CHEMBL4585768) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 520 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514811![]() (CHEMBL4564658) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514799![]() (CHEMBL4445770) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514816![]() (CHEMBL4468868) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514800![]() (CHEMBL4449343) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 630 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514819![]() (CHEMBL4446241) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514821![]() (CHEMBL4451720) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 980 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514820![]() (CHEMBL4437576) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514801![]() (CHEMBL4473196) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514794![]() (CHEMBL4519304) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514812![]() (CHEMBL4564959) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514814![]() (CHEMBL4437700) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514802![]() (CHEMBL4584095) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514803![]() (CHEMBL4547071) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.84E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514798![]() (CHEMBL4554556) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514795![]() (CHEMBL4475464) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.01E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514810![]() (CHEMBL4568317) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514817![]() (CHEMBL4456082) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514808![]() (CHEMBL4444019) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514793![]() (CHEMBL4553074) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514815![]() (CHEMBL4438489) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue... | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50514792![]() (CHEMBL4519240) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 225 | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Binding affinity to human TLR8 ectodomain by isothermal titration calorimetry | J Med Chem 63: 4117-4132 (2020) Article DOI: 10.1021/acs.jmedchem.9b02128 BindingDB Entry DOI: 10.7270/Q2NV9NMG | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |