Compile Data Set for Download or QSAR

Found 69 hits Enz. Inhib. hit(s) with all data for entry = 50008141   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516107 (CHEMBL4591083) Show SMILES COc1ccc(NC(=O)[C@@H]2CCN([C@H](C)C2)c2ncccc2Br)cc1Cl |r| Show InChI InChI=1S/C19H21BrClN3O2/c1-12-10-13(7-9-24(12)18-15(20)4-3-8-22-18)19(25)23-14-5-6-17(26-2)16(21)11-14/h3-6,8,11-13H,7,9-10H2,1-2H3,(H,23,25)/t12-,13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Non-competitive inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus in...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516107 (CHEMBL4591083) Show SMILES COc1ccc(NC(=O)[C@@H]2CCN([C@H](C)C2)c2ncccc2Br)cc1Cl |r| Show InChI InChI=1S/C19H21BrClN3O2/c1-12-10-13(7-9-24(12)18-15(20)4-3-8-22-18)19(25)23-14-5-6-17(26-2)16(21)11-14/h3-6,8,11-13H,7,9-10H2,1-2H3,(H,23,25)/t12-,13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516127 (CHEMBL4559304) Show SMILES Clc1cccnc1N1CCC(CC1)C(=O)Nc1cc(Cl)c2OCC(=O)Nc2c1 Show InChI InChI=1S/C19H18Cl2N4O3/c20-13-2-1-5-22-18(13)25-6-3-11(4-7-25)19(27)23-12-8-14(21)17-15(9-12)24-16(26)10-28-17/h1-2,5,8-9,11H,3-4,6-7,10H2,(H,23,27)(H,24,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516108 (CHEMBL4556101) Show SMILES COc1ccc(NC(=O)C2CCN(C(C)C2)c2ncccc2Br)cc1Cl Show InChI InChI=1S/C19H21BrClN3O2/c1-12-10-13(7-9-24(12)18-15(20)4-3-8-22-18)19(25)23-14-5-6-17(26-2)16(21)11-14/h3-6,8,11-13H,7,9-10H2,1-2H3,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of MALT1-mediated T cell activation in human Jurkat cells assessed in decrease in PMA/ionomycin-induced IL2 production				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516125 (CHEMBL4443047) Show SMILES COc1ncc(NC(=O)C2CCN(CC2)c2ncccc2Br)cc1Cl Show InChI InChI=1S/C17H18BrClN4O2/c1-25-17-14(19)9-12(10-21-17)22-16(24)11-4-7-23(8-5-11)15-13(18)3-2-6-20-15/h2-3,6,9-11H,4-5,7-8H2,1H3,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516105 (CHEMBL4470809) Show SMILES Clc1cccnc1N1CCC(CC1)C(=O)Nc1cnc(OC2CC2)c(Cl)c1 Show InChI InChI=1S/C19H20Cl2N4O2/c20-15-2-1-7-22-17(15)25-8-5-12(6-9-25)18(26)24-13-10-16(21)19(23-11-13)27-14-3-4-14/h1-2,7,10-12,14H,3-6,8-9H2,(H,24,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516108 (CHEMBL4556101) Show SMILES COc1ccc(NC(=O)C2CCN(C(C)C2)c2ncccc2Br)cc1Cl Show InChI InChI=1S/C19H21BrClN3O2/c1-12-10-13(7-9-24(12)18-15(20)4-3-8-22-18)19(25)23-14-5-6-17(26-2)16(21)11-14/h3-6,8,11-13H,7,9-10H2,1-2H3,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516116 (CHEMBL4534539) Show SMILES COc1ccc(NC(=O)C2CCN(CC2)c2ncccc2Br)cc1Cl Show InChI InChI=1S/C18H19BrClN3O2/c1-25-16-5-4-13(11-15(16)20)22-18(24)12-6-9-23(10-7-12)17-14(19)3-2-8-21-17/h2-5,8,11-12H,6-7,9-10H2,1H3,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516107 (CHEMBL4591083) Show SMILES COc1ccc(NC(=O)[C@@H]2CCN([C@H](C)C2)c2ncccc2Br)cc1Cl |r| Show InChI InChI=1S/C19H21BrClN3O2/c1-12-10-13(7-9-24(12)18-15(20)4-3-8-22-18)19(25)23-14-5-6-17(26-2)16(21)11-14/h3-6,8,11-13H,7,9-10H2,1-2H3,(H,23,25)/t12-,13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of MALT1-mediated T cell activation in human Jurkat cells assessed in decrease in PMA/ionomycin-induced IL2 production				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516103 (CHEMBL4551225) Show SMILES COc1ccc(NC(=O)C2CCN(C(C)C2)c2ncccc2C)cc1Cl Show InChI InChI=1S/C20H24ClN3O2/c1-13-5-4-9-22-19(13)24-10-8-15(11-14(24)2)20(25)23-16-6-7-18(26-3)17(21)12-16/h4-7,9,12,14-15H,8,10-11H2,1-3H3,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516103 (CHEMBL4551225) Show SMILES COc1ccc(NC(=O)C2CCN(C(C)C2)c2ncccc2C)cc1Cl Show InChI InChI=1S/C20H24ClN3O2/c1-13-5-4-9-22-19(13)24-10-8-15(11-14(24)2)20(25)23-16-6-7-18(26-3)17(21)12-16/h4-7,9,12,14-15H,8,10-11H2,1-3H3,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of MALT1-mediated T cell activation in human Jurkat cells assessed in decrease in PMA/ionomycin-induced IL2 production				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516107 (CHEMBL4591083) Show SMILES COc1ccc(NC(=O)[C@@H]2CCN([C@H](C)C2)c2ncccc2Br)cc1Cl |r| Show InChI InChI=1S/C19H21BrClN3O2/c1-12-10-13(7-9-24(12)18-15(20)4-3-8-22-18)19(25)23-14-5-6-17(26-2)16(21)11-14/h3-6,8,11-13H,7,9-10H2,1-2H3,(H,23,25)/t12-,13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease E397A mutant (1 to 824 residues) (unknown origin) expressed in baculovirus infec...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516107 (CHEMBL4591083) Show SMILES COc1ccc(NC(=O)[C@@H]2CCN([C@H](C)C2)c2ncccc2Br)cc1Cl |r| Show InChI InChI=1S/C19H21BrClN3O2/c1-12-10-13(7-9-24(12)18-15(20)4-3-8-22-18)19(25)23-14-5-6-17(26-2)16(21)11-14/h3-6,8,11-13H,7,9-10H2,1-2H3,(H,23,25)/t12-,13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of MALT1 protease in human TMD8 cells assessed as reduction in IL10 level incubated for 24 hrs by mesoscale assay kit method				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516107 (CHEMBL4591083) Show SMILES COc1ccc(NC(=O)[C@@H]2CCN([C@H](C)C2)c2ncccc2Br)cc1Cl |r| Show InChI InChI=1S/C19H21BrClN3O2/c1-12-10-13(7-9-24(12)18-15(20)4-3-8-22-18)19(25)23-14-5-6-17(26-2)16(21)11-14/h3-6,8,11-13H,7,9-10H2,1-2H3,(H,23,25)/t12-,13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of MALT1 in human OCI-LY3 cells assessed as reduction in Rel-b cleavage				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516107 (CHEMBL4591083) Show SMILES COc1ccc(NC(=O)[C@@H]2CCN([C@H](C)C2)c2ncccc2Br)cc1Cl |r| Show InChI InChI=1S/C19H21BrClN3O2/c1-12-10-13(7-9-24(12)18-15(20)4-3-8-22-18)19(25)23-14-5-6-17(26-2)16(21)11-14/h3-6,8,11-13H,7,9-10H2,1-2H3,(H,23,25)/t12-,13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of MALT1 protease in human TMD8 cells assessed as reduction in IL6 level incubated for 24 hrs by mesoscale assay kit method				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516143 (CHEMBL4546577) Show SMILES COc1ccc(NC(=O)C2CCN(CC2)c2ncccc2Cl)cc1Cl Show InChI InChI=1S/C18H19Cl2N3O2/c1-25-16-5-4-13(11-15(16)20)22-18(24)12-6-9-23(10-7-12)17-14(19)3-2-8-21-17/h2-5,8,11-12H,6-7,9-10H2,1H3,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516124 (CHEMBL4471046) Show SMILES Clc1cccnc1N1CCC(CC1)C(=O)Nc1cc(Cl)c2occc2c1 Show InChI InChI=1S/C19H17Cl2N3O2/c20-15-2-1-6-22-18(15)24-7-3-12(4-8-24)19(25)23-14-10-13-5-9-26-17(13)16(21)11-14/h1-2,5-6,9-12H,3-4,7-8H2,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516110 (CHEMBL4446759) Show SMILES COc1ccc(NC(=O)C2CCN(CC2)c2ncccc2C)cc1Cl Show InChI InChI=1S/C19H22ClN3O2/c1-13-4-3-9-21-18(13)23-10-7-14(8-11-23)19(24)22-15-5-6-17(25-2)16(20)12-15/h3-6,9,12,14H,7-8,10-11H2,1-2H3,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516108 (CHEMBL4556101) Show SMILES COc1ccc(NC(=O)C2CCN(C(C)C2)c2ncccc2Br)cc1Cl Show InChI InChI=1S/C19H21BrClN3O2/c1-12-10-13(7-9-24(12)18-15(20)4-3-8-22-18)19(25)23-14-5-6-17(26-2)16(21)11-14/h3-6,8,11-13H,7,9-10H2,1-2H3,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of MALT1 in human OCI-LY3 cells assessed as reduction in Rel-b cleavage				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516126 (CHEMBL4460951) Show SMILES COc1cnc(NC(=O)C2CCN(CC2)c2ncccc2Cl)cc1Cl Show InChI InChI=1S/C17H18Cl2N4O2/c1-25-14-10-21-15(9-13(14)19)22-17(24)11-4-7-23(8-5-11)16-12(18)3-2-6-20-16/h2-3,6,9-11H,4-5,7-8H2,1H3,(H,21,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516139 (CHEMBL4565085) Show SMILES Clc1cccnc1N1CCC(CC1)C(=O)Nc1cnc(Oc2cccnc2)c(Cl)c1 Show InChI InChI=1S/C21H19Cl2N5O2/c22-17-4-2-8-25-19(17)28-9-5-14(6-10-28)20(29)27-15-11-18(23)21(26-12-15)30-16-3-1-7-24-13-16/h1-4,7-8,11-14H,5-6,9-10H2,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516142 (CHEMBL4437710) Show SMILES COc1ccc(NC(=O)[C@@H]2CCN([C@@H](C)C2)c2ncccc2Br)cc1Cl |r| Show InChI InChI=1S/C19H21BrClN3O2/c1-12-10-13(7-9-24(12)18-15(20)4-3-8-22-18)19(25)23-14-5-6-17(26-2)16(21)11-14/h3-6,8,11-13H,7,9-10H2,1-2H3,(H,23,25)/t12-,13+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516140 (CHEMBL4550900) Show SMILES COc1ccc(NC(=O)[C@H]2CCN([C@H](C)C2)c2ncccc2Br)cc1Cl |r| Show InChI InChI=1S/C19H21BrClN3O2/c1-12-10-13(7-9-24(12)18-15(20)4-3-8-22-18)19(25)23-14-5-6-17(26-2)16(21)11-14/h3-6,8,11-13H,7,9-10H2,1-2H3,(H,23,25)/t12-,13+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516103 (CHEMBL4551225) Show SMILES COc1ccc(NC(=O)C2CCN(C(C)C2)c2ncccc2C)cc1Cl Show InChI InChI=1S/C20H24ClN3O2/c1-13-5-4-9-22-19(13)24-10-8-15(11-14(24)2)20(25)23-16-6-7-18(26-3)17(21)12-16/h4-7,9,12,14-15H,8,10-11H2,1-3H3,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of MALT1 in human OCI-LY3 cells assessed as reduction in Rel-b cleavage				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516108 (CHEMBL4556101) Show SMILES COc1ccc(NC(=O)C2CCN(C(C)C2)c2ncccc2Br)cc1Cl Show InChI InChI=1S/C19H21BrClN3O2/c1-12-10-13(7-9-24(12)18-15(20)4-3-8-22-18)19(25)23-14-5-6-17(26-2)16(21)11-14/h3-6,8,11-13H,7,9-10H2,1-2H3,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease E397A mutant (1 to 824 residues) (unknown origin) expressed in baculovirus infec...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516121 (CHEMBL4556123) Show SMILES COc1ccc(NC(=O)C2CCN(CC2C)c2ncccc2C)cc1Cl Show InChI InChI=1S/C20H24ClN3O2/c1-13-5-4-9-22-19(13)24-10-8-16(14(2)12-24)20(25)23-15-6-7-18(26-3)17(21)11-15/h4-7,9,11,14,16H,8,10,12H2,1-3H3,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516137 (CHEMBL4541376) Show SMILES COc1ccc(NC(=O)C2CCN(CC2)c2ccccc2Cl)cc1Cl Show InChI InChI=1S/C19H20Cl2N2O2/c1-25-18-7-6-14(12-16(18)21)22-19(24)13-8-10-23(11-9-13)17-5-3-2-4-15(17)20/h2-7,12-13H,8-11H2,1H3,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516108 (CHEMBL4556101) Show SMILES COc1ccc(NC(=O)C2CCN(C(C)C2)c2ncccc2Br)cc1Cl Show InChI InChI=1S/C19H21BrClN3O2/c1-12-10-13(7-9-24(12)18-15(20)4-3-8-22-18)19(25)23-14-5-6-17(26-2)16(21)11-14/h3-6,8,11-13H,7,9-10H2,1-2H3,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of MALT1 protease in human TMD8 cells assessed as reduction in IL6 level incubated for 24 hrs by mesoscale assay kit method				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516122 (CHEMBL4476038) Show SMILES CC[C@@H]1C[C@@H](CCN1c1ncccc1C)C(=O)Nc1ccc(OC)c(Cl)c1 |r| Show InChI InChI=1S/C21H26ClN3O2/c1-4-17-12-15(9-11-25(17)20-14(2)6-5-10-23-20)21(26)24-16-7-8-19(27-3)18(22)13-16/h5-8,10,13,15,17H,4,9,11-12H2,1-3H3,(H,24,26)/t15-,17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516108 (CHEMBL4556101) Show SMILES COc1ccc(NC(=O)C2CCN(C(C)C2)c2ncccc2Br)cc1Cl Show InChI InChI=1S/C19H21BrClN3O2/c1-12-10-13(7-9-24(12)18-15(20)4-3-8-22-18)19(25)23-14-5-6-17(26-2)16(21)11-14/h3-6,8,11-13H,7,9-10H2,1-2H3,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of MALT1 protease in human TMD8 cells assessed as reduction in IL10 level incubated for 24 hrs by mesoscale assay kit method				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516103 (CHEMBL4551225) Show SMILES COc1ccc(NC(=O)C2CCN(C(C)C2)c2ncccc2C)cc1Cl Show InChI InChI=1S/C20H24ClN3O2/c1-13-5-4-9-22-19(13)24-10-8-15(11-14(24)2)20(25)23-16-6-7-18(26-3)17(21)12-16/h4-7,9,12,14-15H,8,10-11H2,1-3H3,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease E397A mutant (1 to 824 residues) (unknown origin) expressed in baculovirus infec...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516135 (CHEMBL4525068) Show SMILES COc1ccc(NC(=O)C2CCN(CC2)c2ncccc2OC)cc1Cl Show InChI InChI=1S/C19H22ClN3O3/c1-25-16-6-5-14(12-15(16)20)22-19(24)13-7-10-23(11-8-13)18-17(26-2)4-3-9-21-18/h3-6,9,12-13H,7-8,10-11H2,1-2H3,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516130 (CHEMBL4594202) Show SMILES COc1ccc(NC(=O)C2CCN(CC2)c2ncccc2C(F)(F)F)cc1Cl Show InChI InChI=1S/C19H19ClF3N3O2/c1-28-16-5-4-13(11-15(16)20)25-18(27)12-6-9-26(10-7-12)17-14(19(21,22)23)3-2-8-24-17/h2-5,8,11-12H,6-7,9-10H2,1H3,(H,25,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516103 (CHEMBL4551225) Show SMILES COc1ccc(NC(=O)C2CCN(C(C)C2)c2ncccc2C)cc1Cl Show InChI InChI=1S/C20H24ClN3O2/c1-13-5-4-9-22-19(13)24-10-8-15(11-14(24)2)20(25)23-16-6-7-18(26-3)17(21)12-16/h4-7,9,12,14-15H,8,10-11H2,1-3H3,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of MALT1 protease in human TMD8 cells assessed as reduction in IL10 level incubated for 24 hrs by mesoscale assay kit method				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516110 (CHEMBL4446759) Show SMILES COc1ccc(NC(=O)C2CCN(CC2)c2ncccc2C)cc1Cl Show InChI InChI=1S/C19H22ClN3O2/c1-13-4-3-9-21-18(13)23-10-7-14(8-11-23)19(24)22-15-5-6-17(25-2)16(20)12-15/h3-6,9,12,14H,7-8,10-11H2,1-2H3,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease E397A mutant (1 to 824 residues) (unknown origin) expressed in baculovirus infec...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516103 (CHEMBL4551225) Show SMILES COc1ccc(NC(=O)C2CCN(C(C)C2)c2ncccc2C)cc1Cl Show InChI InChI=1S/C20H24ClN3O2/c1-13-5-4-9-22-19(13)24-10-8-15(11-14(24)2)20(25)23-16-6-7-18(26-3)17(21)12-16/h4-7,9,12,14-15H,8,10-11H2,1-3H3,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of MALT1 protease in human TMD8 cells assessed as reduction in IL6 level incubated for 24 hrs by mesoscale assay kit method				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516128 (CHEMBL4537193) Show SMILES Clc1cccnc1N1CCC(CC1)C(=O)Nc1ccc2OCC(=O)Nc2c1 Show InChI InChI=1S/C19H19ClN4O3/c20-14-2-1-7-21-18(14)24-8-5-12(6-9-24)19(26)22-13-3-4-16-15(10-13)23-17(25)11-27-16/h1-4,7,10,12H,5-6,8-9,11H2,(H,22,26)(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516136 (CHEMBL4442542) Show SMILES COc1ccc(NC(=O)C2CCN(CC2)c2nc(C)ccc2Cl)cc1Cl Show InChI InChI=1S/C19H21Cl2N3O2/c1-12-3-5-15(20)18(22-12)24-9-7-13(8-10-24)19(25)23-14-4-6-17(26-2)16(21)11-14/h3-6,11,13H,7-10H2,1-2H3,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516110 (CHEMBL4446759) Show SMILES COc1ccc(NC(=O)C2CCN(CC2)c2ncccc2C)cc1Cl Show InChI InChI=1S/C19H22ClN3O2/c1-13-4-3-9-21-18(13)23-10-7-14(8-11-23)19(24)22-15-5-6-17(25-2)16(20)12-15/h3-6,9,12,14H,7-8,10-11H2,1-2H3,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of MALT1 in human OCI-LY3 cells assessed as reduction in Rel-b cleavage				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516106 (CHEMBL4567817) Show SMILES COc1ccc(NC(=O)C2CCN(CC2)c2nccc3sccc23)cc1Cl Show InChI InChI=1S/C20H20ClN3O2S/c1-26-17-3-2-14(12-16(17)21)23-20(25)13-5-9-24(10-6-13)19-15-7-11-27-18(15)4-8-22-19/h2-4,7-8,11-13H,5-6,9-10H2,1H3,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516110 (CHEMBL4446759) Show SMILES COc1ccc(NC(=O)C2CCN(CC2)c2ncccc2C)cc1Cl Show InChI InChI=1S/C19H22ClN3O2/c1-13-4-3-9-21-18(13)23-10-7-14(8-11-23)19(24)22-15-5-6-17(25-2)16(20)12-15/h3-6,9,12,14H,7-8,10-11H2,1-2H3,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of MALT1 protease in human TMD8 cells assessed as reduction in IL10 level incubated for 24 hrs by mesoscale assay kit method				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516117 (CHEMBL4562750) Show SMILES CCc1cccnc1N1CCC(CC1)C(=O)Nc1ccc(OC)c(Cl)c1 Show InChI InChI=1S/C20H24ClN3O2/c1-3-14-5-4-10-22-19(14)24-11-8-15(9-12-24)20(25)23-16-6-7-18(26-2)17(21)13-16/h4-7,10,13,15H,3,8-9,11-12H2,1-2H3,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516102 (CHEMBL4457755) Show SMILES COc1ccc(NC(=O)C2CCN(CC2)c2ncccc2SC)cc1Cl Show InChI InChI=1S/C19H22ClN3O2S/c1-25-16-6-5-14(12-15(16)20)22-19(24)13-7-10-23(11-8-13)18-17(26-2)4-3-9-21-18/h3-6,9,12-13H,7-8,10-11H2,1-2H3,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516132 (CHEMBL4471723) Show SMILES CNc1ncc(NC(=O)C2CCN(CC2)c2ncccc2Cl)cc1Cl Show InChI InChI=1S/C17H19Cl2N5O/c1-20-15-14(19)9-12(10-22-15)23-17(25)11-4-7-24(8-5-11)16-13(18)3-2-6-21-16/h2-3,6,9-11H,4-5,7-8H2,1H3,(H,20,22)(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516110 (CHEMBL4446759) Show SMILES COc1ccc(NC(=O)C2CCN(CC2)c2ncccc2C)cc1Cl Show InChI InChI=1S/C19H22ClN3O2/c1-13-4-3-9-21-18(13)23-10-7-14(8-11-23)19(24)22-15-5-6-17(25-2)16(20)12-15/h3-6,9,12,14H,7-8,10-11H2,1-2H3,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of MALT1-mediated T cell activation in human Jurkat cells assessed in decrease in PMA/ionomycin-induced IL2 production				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516110 (CHEMBL4446759) Show SMILES COc1ccc(NC(=O)C2CCN(CC2)c2ncccc2C)cc1Cl Show InChI InChI=1S/C19H22ClN3O2/c1-13-4-3-9-21-18(13)23-10-7-14(8-11-23)19(24)22-15-5-6-17(25-2)16(20)12-15/h3-6,9,12,14H,7-8,10-11H2,1-2H3,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of MALT1 protease in human TMD8 cells assessed as reduction in IL6 level incubated for 24 hrs by mesoscale assay kit method				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516114 (CHEMBL4536750) Show SMILES COc1ccc(NC(=O)C2CCN(CC2)c2nccn3cccc23)cc1Cl Show InChI InChI=1S/C20H21ClN4O2/c1-27-18-5-4-15(13-16(18)21)23-20(26)14-6-10-25(11-7-14)19-17-3-2-9-24(17)12-8-22-19/h2-5,8-9,12-14H,6-7,10-11H2,1H3,(H,23,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516112 (CHEMBL4530029) Show SMILES COc1ccc(NC(=O)C2CCN(CC2)c2nccc3ccsc23)cc1Cl Show InChI InChI=1S/C20H20ClN3O2S/c1-26-17-3-2-15(12-16(17)21)23-20(25)14-5-9-24(10-6-14)19-18-13(4-8-22-19)7-11-27-18/h2-4,7-8,11-12,14H,5-6,9-10H2,1H3,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516106 (CHEMBL4567817) Show SMILES COc1ccc(NC(=O)C2CCN(CC2)c2nccc3sccc23)cc1Cl Show InChI InChI=1S/C20H20ClN3O2S/c1-26-17-3-2-14(12-16(17)21)23-20(25)13-5-9-24(10-6-13)19-15-7-11-27-18(15)4-8-22-19/h2-4,7-8,11-13H,5-6,9-10H2,1H3,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of MALT1 in human OCI-LY3 cells assessed as reduction in Rel-b cleavage				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516106 (CHEMBL4567817) Show SMILES COc1ccc(NC(=O)C2CCN(CC2)c2nccc3sccc23)cc1Cl Show InChI InChI=1S/C20H20ClN3O2S/c1-26-17-3-2-14(12-16(17)21)23-20(25)13-5-9-24(10-6-13)19-15-7-11-27-18(15)4-8-22-19/h2-4,7-8,11-13H,5-6,9-10H2,1H3,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of MALT1 protease in human TMD8 cells assessed as reduction in IL6 level incubated for 24 hrs by mesoscale assay kit method				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair

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