Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50518668![]() (CHEMBL4546569) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Tianjin Medical University Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptake | Bioorg Med Chem Lett 29: 383-388 (2019) Article DOI: 10.1016/j.bmcl.2018.12.036 BindingDB Entry DOI: 10.7270/Q2MP56PF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50518676![]() (CHEMBL4453888) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 94 | n/a | n/a | n/a | n/a | n/a | n/a |
Tianjin Medical University Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptake | Bioorg Med Chem Lett 29: 383-388 (2019) Article DOI: 10.1016/j.bmcl.2018.12.036 BindingDB Entry DOI: 10.7270/Q2MP56PF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50518675![]() (CHEMBL4458898) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
Tianjin Medical University Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptake | Bioorg Med Chem Lett 29: 383-388 (2019) Article DOI: 10.1016/j.bmcl.2018.12.036 BindingDB Entry DOI: 10.7270/Q2MP56PF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50518679![]() (CHEMBL4468962) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 640 | n/a | n/a | n/a | n/a | n/a | n/a |
Tianjin Medical University Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptake | Bioorg Med Chem Lett 29: 383-388 (2019) Article DOI: 10.1016/j.bmcl.2018.12.036 BindingDB Entry DOI: 10.7270/Q2MP56PF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50518673![]() (CHEMBL4448964) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.55E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tianjin Medical University Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptake | Bioorg Med Chem Lett 29: 383-388 (2019) Article DOI: 10.1016/j.bmcl.2018.12.036 BindingDB Entry DOI: 10.7270/Q2MP56PF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50518665![]() (CHEMBL4445587) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.66E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tianjin Medical University Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptake | Bioorg Med Chem Lett 29: 383-388 (2019) Article DOI: 10.1016/j.bmcl.2018.12.036 BindingDB Entry DOI: 10.7270/Q2MP56PF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50518667![]() (CHEMBL4585746) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tianjin Medical University Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptake | Bioorg Med Chem Lett 29: 383-388 (2019) Article DOI: 10.1016/j.bmcl.2018.12.036 BindingDB Entry DOI: 10.7270/Q2MP56PF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50518661![]() (CHEMBL4554148) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tianjin Medical University Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptake | Bioorg Med Chem Lett 29: 383-388 (2019) Article DOI: 10.1016/j.bmcl.2018.12.036 BindingDB Entry DOI: 10.7270/Q2MP56PF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50518666![]() (CHEMBL4556590) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.79E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tianjin Medical University Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptake | Bioorg Med Chem Lett 29: 383-388 (2019) Article DOI: 10.1016/j.bmcl.2018.12.036 BindingDB Entry DOI: 10.7270/Q2MP56PF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50518671![]() (CHEMBL4560122) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tianjin Medical University Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptake | Bioorg Med Chem Lett 29: 383-388 (2019) Article DOI: 10.1016/j.bmcl.2018.12.036 BindingDB Entry DOI: 10.7270/Q2MP56PF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50518680![]() (CHEMBL4573946) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tianjin Medical University Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptake | Bioorg Med Chem Lett 29: 383-388 (2019) Article DOI: 10.1016/j.bmcl.2018.12.036 BindingDB Entry DOI: 10.7270/Q2MP56PF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50518677![]() (CHEMBL4467680) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tianjin Medical University Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptake | Bioorg Med Chem Lett 29: 383-388 (2019) Article DOI: 10.1016/j.bmcl.2018.12.036 BindingDB Entry DOI: 10.7270/Q2MP56PF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50518664![]() (CHEMBL4473863) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tianjin Medical University Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptake | Bioorg Med Chem Lett 29: 383-388 (2019) Article DOI: 10.1016/j.bmcl.2018.12.036 BindingDB Entry DOI: 10.7270/Q2MP56PF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50518678![]() (CHEMBL4516802) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.38E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tianjin Medical University Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptake | Bioorg Med Chem Lett 29: 383-388 (2019) Article DOI: 10.1016/j.bmcl.2018.12.036 BindingDB Entry DOI: 10.7270/Q2MP56PF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM37953![]() (US10093631, Compound Lesinurad | US10336710, Lesin...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tianjin Medical University Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptake | Bioorg Med Chem Lett 29: 383-388 (2019) Article DOI: 10.1016/j.bmcl.2018.12.036 BindingDB Entry DOI: 10.7270/Q2MP56PF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM37953![]() (US10093631, Compound Lesinurad | US10336710, Lesin...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tianjin Medical University Curated by ChEMBL | Assay Description Inhibition of human URAT1 | Bioorg Med Chem Lett 29: 383-388 (2019) Article DOI: 10.1016/j.bmcl.2018.12.036 BindingDB Entry DOI: 10.7270/Q2MP56PF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50518662![]() (CHEMBL4436938) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tianjin Medical University Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptake | Bioorg Med Chem Lett 29: 383-388 (2019) Article DOI: 10.1016/j.bmcl.2018.12.036 BindingDB Entry DOI: 10.7270/Q2MP56PF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50518663![]() (CHEMBL4551589) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.06E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tianjin Medical University Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptake | Bioorg Med Chem Lett 29: 383-388 (2019) Article DOI: 10.1016/j.bmcl.2018.12.036 BindingDB Entry DOI: 10.7270/Q2MP56PF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50518670![]() (CHEMBL4568207) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.44E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tianjin Medical University Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptake | Bioorg Med Chem Lett 29: 383-388 (2019) Article DOI: 10.1016/j.bmcl.2018.12.036 BindingDB Entry DOI: 10.7270/Q2MP56PF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50518669![]() (CHEMBL4517057) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.58E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tianjin Medical University Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptake | Bioorg Med Chem Lett 29: 383-388 (2019) Article DOI: 10.1016/j.bmcl.2018.12.036 BindingDB Entry DOI: 10.7270/Q2MP56PF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50518672![]() (CHEMBL4594032) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.19E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Tianjin Medical University Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptake | Bioorg Med Chem Lett 29: 383-388 (2019) Article DOI: 10.1016/j.bmcl.2018.12.036 BindingDB Entry DOI: 10.7270/Q2MP56PF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 12 (Homo sapiens (Human)) | BDBM50518674![]() (CHEMBL4459618) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.65E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Tianjin Medical University Curated by ChEMBL | Assay Description Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptake | Bioorg Med Chem Lett 29: 383-388 (2019) Article DOI: 10.1016/j.bmcl.2018.12.036 BindingDB Entry DOI: 10.7270/Q2MP56PF | |||||||||||
More data for this Ligand-Target Pair |