BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 47 hits Enz. Inhib. hit(s) with all data for entry = 50008419   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Chloride anion exchanger


(Mus musculus)		BDBM50519196
PNG
(CHEMBL4436134)
Show SMILES Cc1c(OCc2cccc(c2)C(F)(F)F)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C21H17F3O5/c1-11-15-6-7-17(12(2)19(15)29-20(27)16(11)9-18(25)26)28-10-13-4-3-5-14(8-13)21(22,23)24/h3-8H,9-10H2,1-2H3,(H,25,26)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
PDB
UniChem
Article
PubMed
n/an/a 23n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/bicarbonate...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519196
PNG
(CHEMBL4436134)
Show SMILES Cc1c(OCc2cccc(c2)C(F)(F)F)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C21H17F3O5/c1-11-15-6-7-17(12(2)19(15)29-20(27)16(11)9-18(25)26)28-10-13-4-3-5-14(8-13)21(22,23)24/h3-8H,9-10H2,1-2H3,(H,25,26)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
PDB
UniChem
Article
PubMed
n/an/a 25n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519191
PNG
(CHEMBL4464849)
Show SMILES Cc1c(OCc2cccc(I)c2)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C20H17IO5/c1-11-15-6-7-17(25-10-13-4-3-5-14(21)8-13)12(2)19(15)26-20(24)16(11)9-18(22)23/h3-8H,9-10H2,1-2H3,(H,22,23)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 35n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/bicarbonate...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519191
PNG
(CHEMBL4464849)
Show SMILES Cc1c(OCc2cccc(I)c2)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C20H17IO5/c1-11-15-6-7-17(25-10-13-4-3-5-14(21)8-13)12(2)19(15)26-20(24)16(11)9-18(22)23/h3-8H,9-10H2,1-2H3,(H,22,23)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 40n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519198
PNG
(CHEMBL4469522)
Show SMILES Cc1c(OCc2cc(F)cc(c2)C(F)(F)F)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C21H16F4O5/c1-10-15-3-4-17(11(2)19(15)30-20(28)16(10)8-18(26)27)29-9-12-5-13(21(23,24)25)7-14(22)6-12/h3-7H,8-9H2,1-2H3,(H,26,27)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 60n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519207
PNG
(CHEMBL4442662)
Show SMILES Cc1c(OCc2cccc(c2)C2CC2)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C23H22O5/c1-13-18-8-9-20(14(2)22(18)28-23(26)19(13)11-21(24)25)27-12-15-4-3-5-17(10-15)16-6-7-16/h3-5,8-10,16H,6-7,11-12H2,1-2H3,(H,24,25)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 70n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519172
PNG
(CHEMBL4562582)
Show SMILES Cc1c(OCc2cc(ccc2F)C(F)(F)F)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C21H16F4O5/c1-10-14-4-6-17(11(2)19(14)30-20(28)15(10)8-18(26)27)29-9-12-7-13(21(23,24)25)3-5-16(12)22/h3-7H,8-9H2,1-2H3,(H,26,27)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 100n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519206
PNG
(CHEMBL4544784)
Show SMILES Cc1c(OCc2cccc(Br)c2)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C20H17BrO5/c1-11-15-6-7-17(25-10-13-4-3-5-14(21)8-13)12(2)19(15)26-20(24)16(11)9-18(22)23/h3-8H,9-10H2,1-2H3,(H,22,23)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/a 150n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519185
PNG
(CHEMBL4445315)
Show SMILES Cc1c(OCc2ccc(o2)C(F)(F)F)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C19H15F3O6/c1-9-12-4-5-14(26-8-11-3-6-15(27-11)19(20,21)22)10(2)17(12)28-18(25)13(9)7-16(23)24/h3-6H,7-8H2,1-2H3,(H,23,24)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 300n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519171
PNG
(CHEMBL4457710)
Show SMILES Cc1c(OCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C22H16F6O5/c1-10-15-3-4-17(11(2)19(15)33-20(31)16(10)8-18(29)30)32-9-12-5-13(21(23,24)25)7-14(6-12)22(26,27)28/h3-7H,8-9H2,1-2H3,(H,29,30)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 300n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519203
PNG
(CHEMBL4550735)
Show SMILES Cc1c(OCc2cccc(Br)c2)ccc2cc(C(=O)NO)c(=O)oc12
Show InChI InChI=1S/C18H14BrNO5/c1-10-15(24-9-11-3-2-4-13(19)7-11)6-5-12-8-14(17(21)20-23)18(22)25-16(10)12/h2-8,23H,9H2,1H3,(H,20,21)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 450n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519173
PNG
(CHEMBL4573104)
Show SMILES Cc1cccc(COc2ccc3c(C)c(CC(O)=O)c(=O)oc3c2C)c1
Show InChI InChI=1S/C21H20O5/c1-12-5-4-6-15(9-12)11-25-18-8-7-16-13(2)17(10-19(22)23)21(24)26-20(16)14(18)3/h4-9H,10-11H2,1-3H3,(H,22,23)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/a 500n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519195
PNG
(CHEMBL4469915)
Show SMILES Cc1c(OCc2cccc(c2)[N+]([O-])=O)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C20H17NO7/c1-11-15-6-7-17(27-10-13-4-3-5-14(8-13)21(25)26)12(2)19(15)28-20(24)16(11)9-18(22)23/h3-8H,9-10H2,1-2H3,(H,22,23)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 500n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519194
PNG
(CHEMBL4535284)
Show SMILES Cc1c(OCc2cccc(F)c2)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C20H17FO5/c1-11-15-6-7-17(25-10-13-4-3-5-14(21)8-13)12(2)19(15)26-20(24)16(11)9-18(22)23/h3-8H,9-10H2,1-2H3,(H,22,23)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/a 900n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519179
PNG
(CHEMBL4449383)
Show SMILES CCCCCOc1ccc2c(C)c(CC(O)=O)c(=O)oc2c1C
Show InChI InChI=1S/C18H22O5/c1-4-5-6-9-22-15-8-7-13-11(2)14(10-16(19)20)18(21)23-17(13)12(15)3/h7-8H,4-6,9-10H2,1-3H3,(H,19,20)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519167
PNG
(CHEMBL4556219)
Show SMILES Cc1c(OCc2cccc(Cl)c2)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C20H17ClO5/c1-11-15-6-7-17(25-10-13-4-3-5-14(21)8-13)12(2)19(15)26-20(24)16(11)9-18(22)23/h3-8H,9-10H2,1-2H3,(H,22,23)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519200
PNG
(CHEMBL4471827)
Show SMILES CCCCOc1ccc2c(C)c(CC(O)=O)c(=O)oc2c1C
Show InChI InChI=1S/C17H20O5/c1-4-5-8-21-14-7-6-12-10(2)13(9-15(18)19)17(20)22-16(12)11(14)3/h6-7H,4-5,8-9H2,1-3H3,(H,18,19)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519180
PNG
(CHEMBL4437250)
Show SMILES CCCCCCOc1ccc2c(C)c(CC(O)=O)c(=O)oc2c1C
Show InChI InChI=1S/C19H24O5/c1-4-5-6-7-10-23-16-9-8-14-12(2)15(11-17(20)21)19(22)24-18(14)13(16)3/h8-9H,4-7,10-11H2,1-3H3,(H,20,21)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519181
PNG
(CHEMBL4462339)
Show SMILES Cc1c(OCC2CCCC2)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C19H22O5/c1-11-14-7-8-16(23-10-13-5-3-4-6-13)12(2)18(14)24-19(22)15(11)9-17(20)21/h7-8,13H,3-6,9-10H2,1-2H3,(H,20,21)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.80E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519186
PNG
(CHEMBL4448987)
Show SMILES Cc1c(OCc2cccc(Br)c2)ccc2c(C)c(CC(N)=O)c(=O)oc12
Show InChI InChI=1S/C20H18BrNO4/c1-11-15-6-7-17(25-10-13-4-3-5-14(21)8-13)12(2)19(15)26-20(24)16(11)9-18(22)23/h3-8H,9-10H2,1-2H3,(H2,22,23)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.30E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519169
PNG
(CHEMBL4441522)
Show SMILES Cc1c(OCC2CCC2)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C18H20O5/c1-10-13-6-7-15(22-9-12-4-3-5-12)11(2)17(13)23-18(21)14(10)8-16(19)20/h6-7,12H,3-5,8-9H2,1-2H3,(H,19,20)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.40E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519201
PNG
(CHEMBL4591281)
Show SMILES Cc1c(OC2CCCC2)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C18H20O5/c1-10-13-7-8-15(22-12-5-3-4-6-12)11(2)17(13)23-18(21)14(10)9-16(19)20/h7-8,12H,3-6,9H2,1-2H3,(H,19,20)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.50E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519192
PNG
(CHEMBL4466331)
Show SMILES Cc1c(CC(O)=O)c(=O)oc2c(C)c(OCc3ccccc3I)ccc12
Show InChI InChI=1S/C20H17IO5/c1-11-14-7-8-17(25-10-13-5-3-4-6-16(13)21)12(2)19(14)26-20(24)15(11)9-18(22)23/h3-8H,9-10H2,1-2H3,(H,22,23)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.50E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519177
PNG
(CHEMBL4438070)
Show SMILES Cc1c(CC(O)=O)c(=O)oc2c(C)c(OCC(O)=O)ccc12
Show InChI InChI=1S/C15H14O7/c1-7-9-3-4-11(21-6-13(18)19)8(2)14(9)22-15(20)10(7)5-12(16)17/h3-4H,5-6H2,1-2H3,(H,16,17)(H,18,19)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519176
PNG
(CHEMBL4574007)
Show SMILES Cc1c(OCC=C)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C16H16O5/c1-4-7-20-13-6-5-11-9(2)12(8-14(17)18)16(19)21-15(11)10(13)3/h4-6H,1,7-8H2,2-3H3,(H,17,18)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519175
PNG
(CHEMBL4593314)
Show SMILES Cc1c(OCc2cccc(Br)c2)ccc2cc(C(N)=O)c(=O)oc12
Show InChI InChI=1S/C18H14BrNO4/c1-10-15(23-9-11-3-2-4-13(19)7-11)6-5-12-8-14(17(20)21)18(22)24-16(10)12/h2-8H,9H2,1H3,(H2,20,21)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519174
PNG
(CHEMBL4469295)
Show SMILES Cc1c(OCc2cccc(I)c2)ccc2cc(C(O)=O)c(=O)oc12
Show InChI InChI=1S/C18H13IO5/c1-10-15(23-9-11-3-2-4-13(19)7-11)6-5-12-8-14(17(20)21)18(22)24-16(10)12/h2-8H,9H2,1H3,(H,20,21)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519170
PNG
(CHEMBL4468266)
Show SMILES Cc1c(CC(O)=O)c(=O)oc2c(C)c(OCCn3cccc3)ccc12
Show InChI InChI=1S/C19H19NO5/c1-12-14-5-6-16(24-10-9-20-7-3-4-8-20)13(2)18(14)25-19(23)15(12)11-17(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519199
PNG
(CHEMBL4435168)
Show SMILES Cc1c(OCc2cccc(n2)C(F)(F)F)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C20H16F3NO5/c1-10-13-6-7-15(11(2)18(13)29-19(27)14(10)8-17(25)26)28-9-12-4-3-5-16(24-12)20(21,22)23/h3-7H,8-9H2,1-2H3,(H,25,26)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519178
PNG
(CHEMBL4460418)
Show SMILES CCCOc1ccc2c(C)c(CC(O)=O)c(=O)oc2c1C
Show InChI InChI=1S/C16H18O5/c1-4-7-20-13-6-5-11-9(2)12(8-14(17)18)16(19)21-15(11)10(13)3/h5-6H,4,7-8H2,1-3H3,(H,17,18)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519190
PNG
(CHEMBL4458462)
Show SMILES Cc1c(OCc2cccc(I)c2)ccc2c(C)c(CCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C21H19IO5/c1-12-16-6-8-18(26-11-14-4-3-5-15(22)10-14)13(2)20(16)27-21(25)17(12)7-9-19(23)24/h3-6,8,10H,7,9,11H2,1-2H3,(H,23,24)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519189
PNG
(CHEMBL4572536)
Show SMILES Cc1c(OCc2ccc(I)cc2)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C20H17IO5/c1-11-15-7-8-17(25-10-13-3-5-14(21)6-4-13)12(2)19(15)26-20(24)16(11)9-18(22)23/h3-8H,9-10H2,1-2H3,(H,22,23)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519188
PNG
(CHEMBL4467113)
Show SMILES Cc1c(OCCc2cccc(c2)C(F)(F)F)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C22H19F3O5/c1-12-16-6-7-18(13(2)20(16)30-21(28)17(12)11-19(26)27)29-9-8-14-4-3-5-15(10-14)22(23,24)25/h3-7,10H,8-9,11H2,1-2H3,(H,26,27)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519187
PNG
(CHEMBL4452651)
Show SMILES Cc1c(OCc2cccc(Br)c2)ccc2c(C)c(CCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C21H19BrO5/c1-12-16-6-8-18(26-11-14-4-3-5-15(22)10-14)13(2)20(16)27-21(25)17(12)7-9-19(23)24/h3-6,8,10H,7,9,11H2,1-2H3,(H,23,24)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519184
PNG
(CHEMBL4564240)
Show SMILES Cc1c(OCc2cccc(CO)n2)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C20H19NO6/c1-11-15-6-7-17(26-10-14-5-3-4-13(9-22)21-14)12(2)19(15)27-20(25)16(11)8-18(23)24/h3-7,22H,8-10H2,1-2H3,(H,23,24)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519182
PNG
(CHEMBL4584989)
Show SMILES Cc1c(OCc2ccncc2)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C19H17NO5/c1-11-14-3-4-16(24-10-13-5-7-20-8-6-13)12(2)18(14)25-19(23)15(11)9-17(21)22/h3-8H,9-10H2,1-2H3,(H,21,22)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519183
PNG
(CHEMBL4476453)
Show SMILES Cc1c(OCc2ccccn2)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C19H17NO5/c1-11-14-6-7-16(24-10-13-5-3-4-8-20-13)12(2)18(14)25-19(23)15(11)9-17(21)22/h3-8H,9-10H2,1-2H3,(H,21,22)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519166
PNG
(CHEMBL4585309)
Show SMILES Cc1c(OCc2ccc(Cl)cc2)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C20H17ClO5/c1-11-15-7-8-17(25-10-13-3-5-14(21)6-4-13)12(2)19(15)26-20(24)16(11)9-18(22)23/h3-8H,9-10H2,1-2H3,(H,22,23)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519208
PNG
(CHEMBL4458440)
Show SMILES Cc1c(OCc2cccc(Br)c2)ccc2cc(C(O)=O)c(=O)oc12
Show InChI InChI=1S/C18H13BrO5/c1-10-15(23-9-11-3-2-4-13(19)7-11)6-5-12-8-14(17(20)21)18(22)24-16(10)12/h2-8H,9H2,1H3,(H,20,21)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519202
PNG
(CHEMBL4529721)
Show SMILES Cc1c(OCc2cccnc2)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C19H17NO5/c1-11-14-5-6-16(24-10-13-4-3-7-20-9-13)12(2)18(14)25-19(23)15(11)8-17(21)22/h3-7,9H,8,10H2,1-2H3,(H,21,22)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519204
PNG
(CHEMBL4579127)
Show SMILES Cc1c(OS(=O)(=O)c2cccc(Cl)c2)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C19H15ClO7S/c1-10-14-6-7-16(27-28(24,25)13-5-3-4-12(20)8-13)11(2)18(14)26-19(23)15(10)9-17(21)22/h3-8H,9H2,1-2H3,(H,21,22)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519205
PNG
(CHEMBL4538949)
Show SMILES Cc1c(OCc2ccc(Br)cc2)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C20H17BrO5/c1-11-15-7-8-17(25-10-13-3-5-14(21)6-4-13)12(2)19(15)26-20(24)16(11)9-18(22)23/h3-8H,9-10H2,1-2H3,(H,22,23)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519168
PNG
(CHEMBL4566347)
Show SMILES COCCOc1ccc2c(C)c(CC(O)=O)c(=O)oc2c1C
Show InChI InChI=1S/C16H18O6/c1-9-11-4-5-13(21-7-6-20-3)10(2)15(11)22-16(19)12(9)8-14(17)18/h4-5H,6-8H2,1-3H3,(H,17,18)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519209
PNG
(CHEMBL4436218)
Show SMILES Cc1cccc(c1)S(=O)(=O)Oc1ccc2c(C)c(CC(O)=O)c(=O)oc2c1C
Show InChI InChI=1S/C20H18O7S/c1-11-5-4-6-14(9-11)28(24,25)27-17-8-7-15-12(2)16(10-18(21)22)20(23)26-19(15)13(17)3/h4-9H,10H2,1-3H3,(H,21,22)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM82940
PNG
(2-[7-(2-bromobenzyl)oxy-2-keto-4,8-dimethyl-chrome...)
Show SMILES Cc1c(CC(O)=O)c(=O)oc2c(C)c(OCc3ccccc3Br)ccc12
Show InChI InChI=1S/C20H17BrO5/c1-11-14-7-8-17(25-10-13-5-3-4-6-16(13)21)12(2)19(14)26-20(24)15(11)9-18(22)23/h3-8H,9-10H2,1-2H3,(H,22,23)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519197
PNG
(CHEMBL1491046)
Show SMILES Cc1cc(C)cc(COc2ccc3c(C)c(CC(O)=O)c(=O)oc3c2C)c1
Show InChI InChI=1S/C22H22O5/c1-12-7-13(2)9-16(8-12)11-26-19-6-5-17-14(3)18(10-20(23)24)22(25)27-21(17)15(19)4/h5-9H,10-11H2,1-4H3,(H,23,24)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.50E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair
Chloride anion exchanger


(Mus musculus)		BDBM50519193
PNG
(CHEMBL4562937)
Show SMILES Cc1c(CC(O)=O)c(=O)oc2c(C)c(OCc3ccccc3Cl)ccc12
Show InChI InChI=1S/C20H17ClO5/c1-11-14-7-8-17(25-10-13-5-3-4-6-16(13)21)12(2)19(14)26-20(24)15(11)9-18(22)23/h3-8H,9-10H2,1-2H3,(H,22,23)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.80E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair