Compile Data Set for Download or QSAR

Found 34 hits Enz. Inhib. hit(s) with all data for entry = 50008947   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523865 (CHEMBL4476495) Show SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-n1ccnc1 Show InChI InChI=1S/C20H15F3N4O4/c1-28-16-6-3-12(9-17(16)29-2)18-25-26-19(30-18)14-10-13(31-20(21,22)23)4-5-15(14)27-8-7-24-11-27/h3-11H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523871 (CHEMBL4551424) Show SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1N1CCOCC1 Show InChI InChI=1S/C21H20F3N3O5/c1-28-17-6-3-13(11-18(17)29-2)19-25-26-20(31-19)15-12-14(32-21(22,23)24)4-5-16(15)27-7-9-30-10-8-27/h3-6,11-12H,7-10H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523878 (CHEMBL4445828) Show SMILES COc1cc(ccc1OCC1CC1)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C22H18F3N5O4/c1-31-19-8-14(4-7-18(19)32-10-13-2-3-13)20-28-29-21(33-20)16-9-15(34-22(23,24)25)5-6-17(16)30-12-26-11-27-30/h4-9,11-13H,2-3,10H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523866 (CHEMBL4572513) Show SMILES COc1ccc(cc1OC)-c1noc(n1)-c1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C19H14F3N5O4/c1-28-15-6-3-11(7-16(15)29-2)17-25-18(31-26-17)13-8-12(30-19(20,21)22)4-5-14(13)27-10-23-9-24-27/h3-10H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523870 (CHEMBL4470938) Show SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-c1ccnn1C Show InChI InChI=1S/C21H17F3N4O4/c1-28-16(8-9-25-28)14-6-5-13(32-21(22,23)24)11-15(14)20-27-26-19(31-20)12-4-7-17(29-2)18(10-12)30-3/h4-11H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523889 (CHEMBL4458158) Show SMILES COc1cc(ccc1OC1CCC1)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C22H18F3N5O4/c1-31-19-9-13(5-8-18(19)32-14-3-2-4-14)20-28-29-21(33-20)16-10-15(34-22(23,24)25)6-7-17(16)30-12-26-11-27-30/h5-12,14H,2-4H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523881 (CHEMBL4465794) Show SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C19H14F3N5O4/c1-28-15-6-3-11(7-16(15)29-2)17-25-26-18(30-17)13-8-12(31-19(20,21)22)4-5-14(13)27-10-23-9-24-27/h3-10H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523863 (CHEMBL4552061) Show SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-n1cccn1 Show InChI InChI=1S/C20H15F3N4O4/c1-28-16-7-4-12(10-17(16)29-2)18-25-26-19(30-18)14-11-13(31-20(21,22)23)5-6-15(14)27-9-3-8-24-27/h3-11H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523884 (CHEMBL4442872) Show SMILES COc1ccc(cc1OC)-c1cnc(o1)-c1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C20H15F3N4O4/c1-28-16-6-3-12(7-17(16)29-2)18-9-25-19(30-18)14-8-13(31-20(21,22)23)4-5-15(14)27-11-24-10-26-27/h3-11H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523879 (CHEMBL4467224) Show SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-c1cn[nH]c1 Show InChI InChI=1S/C20H15F3N4O4/c1-28-16-6-3-11(7-17(16)29-2)18-26-27-19(30-18)15-8-13(31-20(21,22)23)4-5-14(15)12-9-24-25-10-12/h3-10H,1-2H3,(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523868 (CHEMBL4447704) Show SMILES COc1ccc(cc1OC)-c1nc(no1)-c1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C19H14F3N5O4/c1-28-15-6-3-11(7-16(15)29-2)18-25-17(26-31-18)13-8-12(30-19(20,21)22)4-5-14(13)27-10-23-9-24-27/h3-10H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523869 (CHEMBL4452758) Show SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-c1cscn1 Show InChI InChI=1S/C20H14F3N3O4S/c1-27-16-6-3-11(7-17(16)28-2)18-25-26-19(29-18)14-8-12(30-20(21,22)23)4-5-13(14)15-9-31-10-24-15/h3-10H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523888 (CHEMBL4453831) Show SMILES COc1cc(cnc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C18H13F3N6O4/c1-28-14-5-10(7-23-17(14)29-2)15-25-26-16(30-15)12-6-11(31-18(19,20)21)3-4-13(12)27-9-22-8-24-27/h3-9H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523872 (CHEMBL4524757) Show SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1N1CCCCC1 Show InChI InChI=1S/C22H22F3N3O4/c1-29-18-9-6-14(12-19(18)30-2)20-26-27-21(31-20)16-13-15(32-22(23,24)25)7-8-17(16)28-10-4-3-5-11-28/h6-9,12-13H,3-5,10-11H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523867 (CHEMBL4435790) Show SMILES COc1ccc(cc1OC)-c1coc(n1)-c1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C20H15F3N4O4/c1-28-17-6-3-12(7-18(17)29-2)15-9-30-19(26-15)14-8-13(31-20(21,22)23)4-5-16(14)27-11-24-10-25-27/h3-11H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50523865 (CHEMBL4476495) Show SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-n1ccnc1 Show InChI InChI=1S/C20H15F3N4O4/c1-28-16-6-3-12(9-17(16)29-2)18-25-26-19(30-18)14-10-13(31-20(21,22)23)4-5-15(14)27-8-7-24-11-27/h3-11H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of mGlu1 receptor (unknown origin)				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50523865 (CHEMBL4476495) Show SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-n1ccnc1 Show InChI InChI=1S/C20H15F3N4O4/c1-28-16-6-3-12(9-17(16)29-2)18-25-26-19(30-18)14-10-13(31-20(21,22)23)4-5-15(14)27-8-7-24-11-27/h3-11H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of mGlu5 receptor (unknown origin)				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Homo sapiens (Human))	BDBM50523865 (CHEMBL4476495) Show SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-n1ccnc1 Show InChI InChI=1S/C20H15F3N4O4/c1-28-16-6-3-12(9-17(16)29-2)18-25-26-19(30-18)14-10-13(31-20(21,22)23)4-5-15(14)27-8-7-24-11-27/h3-11H,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of mGlu6 receptor (unknown origin)				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 8 (Homo sapiens (Human))	BDBM50523865 (CHEMBL4476495) Show SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-n1ccnc1 Show InChI InChI=1S/C20H15F3N4O4/c1-28-16-6-3-12(9-17(16)29-2)18-25-26-19(30-18)14-10-13(31-20(21,22)23)4-5-15(14)27-8-7-24-11-27/h3-11H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of mGlu8 receptor (unknown origin)				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50523865 (CHEMBL4476495) Show SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-n1ccnc1 Show InChI InChI=1S/C20H15F3N4O4/c1-28-16-6-3-12(9-17(16)29-2)18-25-26-19(30-18)14-10-13(31-20(21,22)23)4-5-15(14)27-8-7-24-11-27/h3-11H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of mGlu4 receptor (unknown origin)				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50523865 (CHEMBL4476495) Show SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-n1ccnc1 Show InChI InChI=1S/C20H15F3N4O4/c1-28-16-6-3-12(9-17(16)29-2)18-25-26-19(30-18)14-10-13(31-20(21,22)23)4-5-15(14)27-8-7-24-11-27/h3-11H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of mGlu3 receptor (unknown origin)				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50523865 (CHEMBL4476495) Show SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-n1ccnc1 Show InChI InChI=1S/C20H15F3N4O4/c1-28-16-6-3-12(9-17(16)29-2)18-25-26-19(30-18)14-10-13(31-20(21,22)23)4-5-15(14)27-8-7-24-11-27/h3-11H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of mGlu2 receptor (unknown origin)				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523880 (CHEMBL4548116) Show SMILES COc1cc(ccc1F)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C18H11F4N5O3/c1-28-15-6-10(2-4-13(15)19)16-25-26-17(29-16)12-7-11(30-18(20,21)22)3-5-14(12)27-9-23-8-24-27/h2-9H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523875 (CHEMBL4474756) Show SMILES FC(F)(F)Oc1ccc(c(c1)-c1nnc(o1)-c1ccc2OCCOc2c1)-n1cncn1 Show InChI InChI=1S/C19H12F3N5O4/c20-19(21,22)31-12-2-3-14(27-10-23-9-24-27)13(8-12)18-26-25-17(30-18)11-1-4-15-16(7-11)29-6-5-28-15/h1-4,7-10H,5-6H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523882 (CHEMBL4551426) Show SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-c1cccnc1 Show InChI InChI=1S/C22H16F3N3O4/c1-29-18-8-5-13(10-19(18)30-2)20-27-28-21(31-20)17-11-15(32-22(23,24)25)6-7-16(17)14-4-3-9-26-12-14/h3-12H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523883 (CHEMBL4560911) Show SMILES COc1ccc(-c2nnc(o2)-c2cc(OC(F)(F)F)ccc2-n2cncn2)c(F)c1F Show InChI InChI=1S/C18H10F5N5O3/c1-29-13-5-3-10(14(19)15(13)20)16-26-27-17(30-16)11-6-9(31-18(21,22)23)2-4-12(11)28-8-24-7-25-28/h2-8H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523874 (CHEMBL4557876) Show SMILES COc1ccc(cn1)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C17H11F3N6O3/c1-27-14-5-2-10(7-22-14)15-24-25-16(28-15)12-6-11(29-17(18,19)20)3-4-13(12)26-9-21-8-23-26/h2-9H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523877 (CHEMBL4592620) Show SMILES FC(F)(F)Oc1ccc(c(c1)-c1nnc(o1)-c1ccc2OCOc2c1)-n1cncn1 Show InChI InChI=1S/C18H10F3N5O4/c19-18(20,21)30-11-2-3-13(26-8-22-7-23-26)12(6-11)17-25-24-16(29-17)10-1-4-14-15(5-10)28-9-27-14/h1-8H,9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523876 (CHEMBL4588461) Show SMILES FC(F)(F)Oc1ccc(c(c1)-c1nnc(o1)-c1ccc2OC(F)(F)Oc2c1)-n1cncn1 Show InChI InChI=1S/C18H8F5N5O4/c19-17(20,21)30-10-2-3-12(28-8-24-7-25-28)11(6-10)16-27-26-15(29-16)9-1-4-13-14(5-9)32-18(22,23)31-13/h1-8H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523864 (CHEMBL4558967) Show SMILES COc1ccc(cc1F)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C18H11F4N5O3/c1-28-15-5-2-10(6-13(15)19)16-25-26-17(29-16)12-7-11(30-18(20,21)22)3-4-14(12)27-9-23-8-24-27/h2-9H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523873 (CHEMBL4546991) Show SMILES COc1cc(cc(F)c1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C19H13F4N5O4/c1-29-15-6-10(5-13(20)16(15)30-2)17-26-27-18(31-17)12-7-11(32-19(21,22)23)3-4-14(12)28-9-24-8-25-28/h3-9H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523887 (CHEMBL4579325) Show SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1N1CCCC1 Show InChI InChI=1S/C21H20F3N3O4/c1-28-17-8-5-13(11-18(17)29-2)19-25-26-20(30-19)15-12-14(31-21(22,23)24)6-7-16(15)27-9-3-4-10-27/h5-8,11-12H,3-4,9-10H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523886 (CHEMBL4456996) Show SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1N1CCN(C)CC1 Show InChI InChI=1S/C22H23F3N4O4/c1-28-8-10-29(11-9-28)17-6-5-15(33-22(23,24)25)13-16(17)21-27-26-20(32-21)14-4-7-18(30-2)19(12-14)31-3/h4-7,12-13H,8-11H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523885 (CHEMBL4553780) Show SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-c1cnn(C)c1 Show InChI InChI=1S/C21H17F3N4O4/c1-28-11-13(10-25-28)15-6-5-14(32-21(22,23)24)9-16(15)20-27-26-19(31-20)12-4-7-17(29-2)18(8-12)30-3/h4-11H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair