Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein kinase C theta type (Homo sapiens (Human)) | BDBM50525600 (CHEMBL4469412) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of human recombinant full length His tagged PKC theta expressed in baculovirus using ERMRPRKRQGSVRRRV peptide as substrate incubated for 6... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C theta type (Homo sapiens (Human)) | BDBM50525603 (CHEMBL4528271) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of human recombinant full length His tagged PKC theta expressed in baculovirus using ERMRPRKRQGSVRRRV peptide as substrate incubated for 6... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C theta type (Homo sapiens (Human)) | BDBM50525602 (CHEMBL4569479) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of human recombinant full length His tagged PKC theta expressed in baculovirus using ERMRPRKRQGSVRRRV peptide as substrate incubated for 6... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C theta type (Homo sapiens (Human)) | BDBM50525604 (CHEMBL4532737) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | <1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of human recombinant full length His tagged PKC theta expressed in baculovirus using ERMRPRKRQGSVRRRV peptide as substrate incubated for 6... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C theta type (Homo sapiens (Human)) | BDBM50525587 (CHEMBL4589844) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of human recombinant full length His tagged PKC theta expressed in baculovirus using ERMRPRKRQGSVRRRV peptide as substrate incubated for 6... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C theta type (Homo sapiens (Human)) | BDBM50525584 (CHEMBL4453941) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of human recombinant full length His tagged PKC theta expressed in baculovirus using ERMRPRKRQGSVRRRV peptide as substrate incubated for 6... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C theta type (Homo sapiens (Human)) | BDBM50525599 (CHEMBL4461370) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of human recombinant full length His tagged PKC theta expressed in baculovirus using ERMRPRKRQGSVRRRV peptide as substrate incubated for 6... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM50525584 (CHEMBL4453941) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of JAK3 (unknown origin) | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C theta type (Homo sapiens (Human)) | BDBM50525596 (CHEMBL4590477) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of human recombinant full length His tagged PKC theta expressed in baculovirus using ERMRPRKRQGSVRRRV peptide as substrate incubated for 6... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C theta type (Homo sapiens (Human)) | BDBM50525593 (CHEMBL4522851) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of human recombinant full length His tagged PKC theta expressed in baculovirus using ERMRPRKRQGSVRRRV peptide as substrate incubated for 6... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C theta type (Homo sapiens (Human)) | BDBM50525583 (CHEMBL4461649) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of human recombinant full length His tagged PKC theta expressed in baculovirus using ERMRPRKRQGSVRRRV peptide as substrate incubated for 6... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 1/2 (Homo sapiens (Human)) | BDBM50525584 (CHEMBL4453941) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of ROCK (unknown origin) using Myelin Basic Protein as substrate incubated for 60 mins in presence of [33P] gammaATP by microbeta liquid s... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C theta type (Homo sapiens (Human)) | BDBM50525597 (CHEMBL4587816) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of human recombinant full length His tagged PKC theta expressed in baculovirus using ERMRPRKRQGSVRRRV peptide as substrate incubated for 6... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C theta type (Homo sapiens (Human)) | BDBM50525601 (CHEMBL4435004) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of human recombinant full length His tagged PKC theta expressed in baculovirus using ERMRPRKRQGSVRRRV peptide as substrate incubated for 6... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C theta type (Homo sapiens (Human)) | BDBM50525586 (CHEMBL4457150) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of human recombinant full length His tagged PKC theta expressed in baculovirus using ERMRPRKRQGSVRRRV peptide as substrate incubated for 6... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C theta type (Homo sapiens (Human)) | BDBM50525590 (CHEMBL4541215) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of human recombinant full length His tagged PKC theta expressed in baculovirus using ERMRPRKRQGSVRRRV peptide as substrate incubated for 6... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C delta type (Homo sapiens (Human)) | BDBM50525584 (CHEMBL4453941) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of recombinant full length PKC delta (unknown origin) using ERMRPRKR- QGSVRRRV peptide as substrate measured after 15 mins in presence of ... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM50525584 (CHEMBL4453941) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of JAK2 (unknown origin) using polyE4Y peptide as substrate incubated for 60 mins in presence of [33P] gammaATP by microbeta liquid scinti... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C theta type (Homo sapiens (Human)) | BDBM50525594 (CHEMBL4567363) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of human recombinant full length His tagged PKC theta expressed in baculovirus using ERMRPRKRQGSVRRRV peptide as substrate incubated for 6... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C theta type (Homo sapiens (Human)) | BDBM50525588 (CHEMBL4539521) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of human recombinant full length His tagged PKC theta expressed in baculovirus using ERMRPRKRQGSVRRRV peptide as substrate incubated for 6... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C theta type (Homo sapiens (Human)) | BDBM50525591 (CHEMBL4566843) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of human recombinant full length His tagged PKC theta expressed in baculovirus using ERMRPRKRQGSVRRRV peptide as substrate incubated for 6... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C theta type (Homo sapiens (Human)) | BDBM50525592 (CHEMBL4584166) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of human recombinant full length His tagged PKC theta expressed in baculovirus using ERMRPRKRQGSVRRRV peptide as substrate incubated for 6... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C theta type (Homo sapiens (Human)) | BDBM50525598 (CHEMBL4559701) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of human recombinant full length His tagged PKC theta expressed in baculovirus using ERMRPRKRQGSVRRRV peptide as substrate incubated for 6... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C theta type (Homo sapiens (Human)) | BDBM50525585 (CHEMBL4444700) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of human recombinant full length His tagged PKC theta expressed in baculovirus using ERMRPRKRQGSVRRRV peptide as substrate incubated for 6... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-dependent protein kinase catalytic subunit alpha (Homo sapiens (Human)) | BDBM50525586 (CHEMBL4457150) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of protein kinase A (unknown origin) using Kemptide (LRRASLG) as substrate incubated for 15 mins in presence of ATP by spectrophotometric ... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C theta type (Homo sapiens (Human)) | BDBM50525595 (CHEMBL4454086) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of human recombinant full length His tagged PKC theta expressed in baculovirus using ERMRPRKRQGSVRRRV peptide as substrate incubated for 6... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human)) | BDBM50525586 (CHEMBL4457150) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 46 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of FLT3 (unknown origin) using polyE4Y peptide as substrate incubated for 60 mins in presence of [33P] gammaATP by microbeta liquid scinti... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C alpha type (Homo sapiens (Human)) | BDBM50525587 (CHEMBL4589844) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 57 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of recombinant full length PKC alpha (unknown origin) using RRRRRKGSFKRKA peptide as substrate measured after 15 mins in presence of ATP b... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C alpha type (Homo sapiens (Human)) | BDBM50525596 (CHEMBL4590477) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of recombinant full length PKC alpha (unknown origin) using RRRRRKGSFKRKA peptide as substrate measured after 15 mins in presence of ATP b... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C delta type (Homo sapiens (Human)) | BDBM50525587 (CHEMBL4589844) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of recombinant full length PKC delta (unknown origin) using ERMRPRKR- QGSVRRRV peptide as substrate measured after 15 mins in presence of ... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C theta type (Homo sapiens (Human)) | BDBM50525589 (CHEMBL4447253) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 72 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of human recombinant full length His tagged PKC theta expressed in baculovirus using ERMRPRKRQGSVRRRV peptide as substrate incubated for 6... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM50525588 (CHEMBL4539521) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 86 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of JAK2 (unknown origin) using polyE4Y peptide as substrate incubated for 60 mins in presence of [33P] gammaATP by microbeta liquid scinti... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human)) | BDBM50525584 (CHEMBL4453941) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of FLT3 (unknown origin) using polyE4Y peptide as substrate incubated for 60 mins in presence of [33P] gammaATP by microbeta liquid scinti... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-dependent protein kinase catalytic subunit alpha (Homo sapiens (Human)) | BDBM50525584 (CHEMBL4453941) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of protein kinase A (unknown origin) using Kemptide (LRRASLG) as substrate incubated for 15 mins in presence of ATP by spectrophotometric ... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C alpha type (Homo sapiens (Human)) | BDBM50525584 (CHEMBL4453941) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of recombinant full length PKC alpha (unknown origin) using RRRRRKGSFKRKA peptide as substrate measured after 15 mins in presence of ATP b... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C delta type (Homo sapiens (Human)) | BDBM50525596 (CHEMBL4590477) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 135 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of recombinant full length PKC delta (unknown origin) using ERMRPRKR- QGSVRRRV peptide as substrate measured after 15 mins in presence of ... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C delta type (Homo sapiens (Human)) | BDBM50525586 (CHEMBL4457150) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 184 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of recombinant full length PKC delta (unknown origin) using ERMRPRKR- QGSVRRRV peptide as substrate measured after 15 mins in presence of ... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM50525584 (CHEMBL4453941) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of GSK-3beta (unknown origin) using HSSPHQS(PO3H2)EDEEE peptide as substrate measured after 15 mins in presence of ATP by spectrophotometr... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 1/2 (Homo sapiens (Human)) | BDBM50525588 (CHEMBL4539521) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of ROCK (unknown origin) using Myelin Basic Protein as substrate incubated for 60 mins in presence of [33P] gammaATP by microbeta liquid s... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C delta type (Homo sapiens (Human)) | BDBM50525588 (CHEMBL4539521) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of recombinant full length PKC delta (unknown origin) using ERMRPRKR- QGSVRRRV peptide as substrate measured after 15 mins in presence of ... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM50525598 (CHEMBL4559701) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of JAK2 (unknown origin) using polyE4Y peptide as substrate incubated for 60 mins in presence of [33P] gammaATP by microbeta liquid scinti... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C alpha type (Homo sapiens (Human)) | BDBM50525597 (CHEMBL4587816) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 286 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of recombinant full length PKC alpha (unknown origin) using RRRRRKGSFKRKA peptide as substrate measured after 15 mins in presence of ATP b... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C delta type (Homo sapiens (Human)) | BDBM50525583 (CHEMBL4461649) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | 392 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of recombinant full length PKC delta (unknown origin) using ERMRPRKR- QGSVRRRV peptide as substrate measured after 15 mins in presence of ... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C alpha type (Homo sapiens (Human)) | BDBM50525588 (CHEMBL4539521) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 465 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of recombinant full length PKC alpha (unknown origin) using RRRRRKGSFKRKA peptide as substrate measured after 15 mins in presence of ATP b... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C alpha type (Homo sapiens (Human)) | BDBM50525586 (CHEMBL4457150) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 468 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of recombinant full length PKC alpha (unknown origin) using RRRRRKGSFKRKA peptide as substrate measured after 15 mins in presence of ATP b... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C delta type (Homo sapiens (Human)) | BDBM50525597 (CHEMBL4587816) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 542 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of recombinant full length PKC delta (unknown origin) using ERMRPRKR- QGSVRRRV peptide as substrate measured after 15 mins in presence of ... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 1/2 (Homo sapiens (Human)) | BDBM50525598 (CHEMBL4559701) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 560 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of ROCK (unknown origin) using Myelin Basic Protein as substrate incubated for 60 mins in presence of [33P] gammaATP by microbeta liquid s... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C delta type (Homo sapiens (Human)) | BDBM50525598 (CHEMBL4559701) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 584 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of recombinant full length PKC delta (unknown origin) using ERMRPRKR- QGSVRRRV peptide as substrate measured after 15 mins in presence of ... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C alpha type (Homo sapiens (Human)) | BDBM50525583 (CHEMBL4461649) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | 1.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of recombinant full length PKC alpha (unknown origin) using RRRRRKGSFKRKA peptide as substrate measured after 15 mins in presence of ATP b... | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C beta type (Homo sapiens (Human)) | BDBM50525583 (CHEMBL4461649) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of human PKC beta | ACS Med Chem Lett 10: 1134-1139 (2019) Article DOI: 10.1021/acsmedchemlett.9b00134 BindingDB Entry DOI: 10.7270/Q2NC64NR | |||||||||||
More data for this Ligand-Target Pair |
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