Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with all data for entry = 50010195   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50091955 (3-(2-Diethylamino-ethoxy)-5a,11a-dihydro-benzo[b]n...) Show SMILES CCN(CC)CCOc1ccc2c(c1)oc1c(O)c3ccccc3c(O)c21 Show InChI InChI=1S/C22H23NO4/c1-3-23(4-2)11-12-26-14-9-10-17-18(13-14)27-22-19(17)20(24)15-7-5-6-8-16(15)21(22)25/h5-10,13,24-25H,3-4,11-12H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Reading University Curated by ChEMBL					Assay Description Inhibitory activity of the compound was tested against human ovarian cancer cell (A2780 cells) Telomerase				Bioorg Med Chem Lett 10: 2063-6 (2000) BindingDB Entry DOI: 10.7270/Q25T3JQM
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50091956 (CHEMBL292124 | {2-[2-(2-Dimethylamino-ethyl)-indol...) Show SMILES CN(C)CCc1ccc2nc3c(cc2c1)n(CCN(C)C)c1ccccc31 Show InChI InChI=1S/C23H28N4/c1-25(2)12-11-17-9-10-20-18(15-17)16-22-23(24-20)19-7-5-6-8-21(19)27(22)14-13-26(3)4/h5-10,15-16H,11-14H2,1-4H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Reading University Curated by ChEMBL					Assay Description Inhibitory activity of the compound was tested against human ovarian cancer cell (A2780 cells) Telomerase				Bioorg Med Chem Lett 10: 2063-6 (2000) BindingDB Entry DOI: 10.7270/Q25T3JQM
					More data for this Ligand-Target Pair