Compile Data Set for Download or QSAR

Found 108 hits Enz. Inhib. hit(s) with all data for entry = 50010226   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536604 (CHEMBL4594174) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C(C)C)-c1ccc(nc1)N1CCNCC1 Show InChI InChI=1S/C30H37N7O2/c1-5-6-21-13-20(4)35-30(39)25(21)17-33-29(38)24-14-23(15-27-26(24)18-34-37(27)19(2)3)22-7-8-28(32-16-22)36-11-9-31-10-12-36/h7-8,13-16,18-19,31H,5-6,9-12,17H2,1-4H3,(H,33,38)(H,35,39)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536589 (CHEMBL4545986) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C(CC)CC)-c1ccc(nc1)N1CCN(CC1)C(C)C Show InChI InChI=1S/C35H47N7O2/c1-7-10-25-17-24(6)39-35(44)30(25)21-37-34(43)29-18-27(19-32-31(29)22-38-42(32)28(8-2)9-3)26-11-12-33(36-20-26)41-15-13-40(14-16-41)23(4)5/h11-12,17-20,22-23,28H,7-10,13-16,21H2,1-6H3,(H,37,43)(H,39,44)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536579 (CHEMBL4557033) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C(C)C)-c1ccc(nc1)N1CCN(CC)CC1 Show InChI InChI=1S/C32H41N7O2/c1-6-8-23-15-22(5)36-32(41)27(23)19-34-31(40)26-16-25(17-29-28(26)20-35-39(29)21(3)4)24-9-10-30(33-18-24)38-13-11-37(7-2)12-14-38/h9-10,15-18,20-21H,6-8,11-14,19H2,1-5H3,(H,34,40)(H,36,41)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50075071 (CHEMBL3414619) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C(C)C)-c1ccc(nc1)N1CCN(CC1)C(C)C Show InChI InChI=1S/C33H43N7O2/c1-7-8-24-15-23(6)37-33(42)28(24)19-35-32(41)27-16-26(17-30-29(27)20-36-40(30)22(4)5)25-9-10-31(34-18-25)39-13-11-38(12-14-39)21(2)3/h9-10,15-18,20-22H,7-8,11-14,19H2,1-6H3,(H,35,41)(H,37,42)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536574 (CHEMBL4521710) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C1CCCCC1)-c1ccc(nc1)N1CCN(CC1)C(C)C Show InChI InChI=1S/C36H47N7O2/c1-5-9-26-18-25(4)40-36(45)31(26)22-38-35(44)30-19-28(20-33-32(30)23-39-43(33)29-10-7-6-8-11-29)27-12-13-34(37-21-27)42-16-14-41(15-17-42)24(2)3/h12-13,18-21,23-24,29H,5-11,14-17,22H2,1-4H3,(H,38,44)(H,40,45)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536573 (CHEMBL4559875) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C1CCCC1)-c1ccc(nc1)N1CCN(CC1)C(C)C Show InChI InChI=1S/C35H45N7O2/c1-5-8-25-17-24(4)39-35(44)30(25)21-37-34(43)29-18-27(19-32-31(29)22-38-42(32)28-9-6-7-10-28)26-11-12-33(36-20-26)41-15-13-40(14-16-41)23(2)3/h11-12,17-20,22-23,28H,5-10,13-16,21H2,1-4H3,(H,37,43)(H,39,44)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536572 (CHEMBL4539055) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C(C)(C)C)-c1ccc(nc1)N1CCN(CC1)C(C)C Show InChI InChI=1S/C34H45N7O2/c1-8-9-24-16-23(4)38-33(43)28(24)20-36-32(42)27-17-26(18-30-29(27)21-37-41(30)34(5,6)7)25-10-11-31(35-19-25)40-14-12-39(13-15-40)22(2)3/h10-11,16-19,21-22H,8-9,12-15,20H2,1-7H3,(H,36,42)(H,38,43)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536560 (CHEMBL4567859) Show SMILES CC(C)N1CCN(CC1)c1ccc(cn1)-c1cc(C(=O)NCc2c(cc(C)[nH]c2=O)C2CCCC2)c2cnn(C(C)C)c2c1 Show InChI InChI=1S/C35H45N7O2/c1-22(2)40-12-14-41(15-13-40)33-11-10-26(19-36-33)27-17-29(30-21-38-42(23(3)4)32(30)18-27)34(43)37-20-31-28(25-8-6-7-9-25)16-24(5)39-35(31)44/h10-11,16-19,21-23,25H,6-9,12-15,20H2,1-5H3,(H,37,43)(H,39,44)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536563 (CHEMBL4559801) Show SMILES CC(C)N1CCN(CC1)c1ccc(cn1)-c1cc(C(=O)NCc2c(cc(C)[nH]c2=O)C(C)C)c2cnn(C(C)C)c2c1 Show InChI InChI=1S/C33H43N7O2/c1-20(2)26-14-23(7)37-33(42)29(26)18-35-32(41)27-15-25(16-30-28(27)19-36-40(30)22(5)6)24-8-9-31(34-17-24)39-12-10-38(11-13-39)21(3)4/h8-9,14-17,19-22H,10-13,18H2,1-7H3,(H,35,41)(H,37,42)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536585 (CHEMBL4554286) Show SMILES CCCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C(C)C)-c1ccc(nc1)N1CCN(CC1)C(C)C Show InChI InChI=1S/C34H45N7O2/c1-7-8-9-25-16-24(6)38-34(43)29(25)20-36-33(42)28-17-27(18-31-30(28)21-37-41(31)23(4)5)26-10-11-32(35-19-26)40-14-12-39(13-15-40)22(2)3/h10-11,16-19,21-23H,7-9,12-15,20H2,1-6H3,(H,36,42)(H,38,43)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536598 (CHEMBL4551319) Show SMILES CC(C)Cc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C(C)C)-c1ccc(nc1)N1CCN(CC1)C(C)C Show InChI InChI=1S/C34H45N7O2/c1-21(2)14-27-15-24(7)38-34(43)29(27)19-36-33(42)28-16-26(17-31-30(28)20-37-41(31)23(5)6)25-8-9-32(35-18-25)40-12-10-39(11-13-40)22(3)4/h8-9,15-18,20-23H,10-14,19H2,1-7H3,(H,36,42)(H,38,43)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536593 (CHEMBL4569399) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C(C)C)C1CCNCC1 Show InChI InChI=1S/C26H35N5O2/c1-5-6-19-11-17(4)30-26(33)22(19)14-28-25(32)21-12-20(18-7-9-27-10-8-18)13-24-23(21)15-29-31(24)16(2)3/h11-13,15-16,18,27H,5-10,14H2,1-4H3,(H,28,32)(H,30,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536584 (CHEMBL4544978) Show SMILES CCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C(C)C)-c1ccc(nc1)N1CCN(CC1)C(C)C Show InChI InChI=1S/C32H41N7O2/c1-7-23-14-22(6)36-32(41)27(23)18-34-31(40)26-15-25(16-29-28(26)19-35-39(29)21(4)5)24-8-9-30(33-17-24)38-12-10-37(11-13-38)20(2)3/h8-9,14-17,19-21H,7,10-13,18H2,1-6H3,(H,34,40)(H,36,41)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536555 (CHEMBL4532174) Show SMILES CC(C)N1CCN(CC1)c1ccc(cn1)-c1cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c2cnn(C(C)C)c2c1 Show InChI InChI=1S/C31H39N7O2/c1-19(2)36-9-11-37(12-10-36)29-8-7-23(16-32-29)24-14-25(27-18-34-38(20(3)4)28(27)15-24)30(39)33-17-26-21(5)13-22(6)35-31(26)40/h7-8,13-16,18-20H,9-12,17H2,1-6H3,(H,33,39)(H,35,40)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536582 (CHEMBL4575460) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C(C)C)N1CCNCC1 Show InChI InChI=1S/C25H34N6O2/c1-5-6-18-11-17(4)29-25(33)21(18)14-27-24(32)20-12-19(30-9-7-26-8-10-30)13-23-22(20)15-28-31(23)16(2)3/h11-13,15-16,26H,5-10,14H2,1-4H3,(H,27,32)(H,29,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536581 (CHEMBL4593352) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C(C)C)-c1ccc(F)cn1 Show InChI InChI=1S/C26H28FN5O2/c1-5-6-17-9-16(4)31-26(34)21(17)13-29-25(33)20-10-18(23-8-7-19(27)12-28-23)11-24-22(20)14-30-32(24)15(2)3/h7-12,14-15H,5-6,13H2,1-4H3,(H,29,33)(H,31,34)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536562 (CHEMBL4542135) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C(C)C)-c1ccccn1 Show InChI InChI=1S/C26H29N5O2/c1-5-8-18-11-17(4)30-26(33)21(18)14-28-25(32)20-12-19(23-9-6-7-10-27-23)13-24-22(20)15-29-31(24)16(2)3/h6-7,9-13,15-16H,5,8,14H2,1-4H3,(H,28,32)(H,30,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536578 (CHEMBL4529085) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(CCCCCCO)ncc12)-c1ccc(nc1)N1CCN(CC1)C(C)C Show InChI InChI=1S/C36H49N7O3/c1-5-10-27-19-26(4)40-36(46)31(27)23-38-35(45)30-20-29(21-33-32(30)24-39-43(33)13-8-6-7-9-18-44)28-11-12-34(37-22-28)42-16-14-41(15-17-42)25(2)3/h11-12,19-22,24-25,44H,5-10,13-18,23H2,1-4H3,(H,38,45)(H,40,46)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536595 (CHEMBL4535178) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(NC2CCNCC2)cc2n(ncc12)C(C)C Show InChI InChI=1S/C26H36N6O2/c1-5-6-18-11-17(4)30-26(34)22(18)14-28-25(33)21-12-20(31-19-7-9-27-10-8-19)13-24-23(21)15-29-32(24)16(2)3/h11-13,15-16,19,27,31H,5-10,14H2,1-4H3,(H,28,33)(H,30,34)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536567 (CHEMBL4532360) Show SMILES CC(C)N1CCN(CC1)c1ccc(cn1)-c1cc(C(=O)NCc2c3CCCc3c(C)[nH]c2=O)c2cnn(C(C)C)c2c1 Show InChI InChI=1S/C33H41N7O2/c1-20(2)38-11-13-39(14-12-38)31-10-9-23(17-34-31)24-15-27(28-19-36-40(21(3)4)30(28)16-24)32(41)35-18-29-26-8-6-7-25(26)22(5)37-33(29)42/h9-10,15-17,19-21H,6-8,11-14,18H2,1-5H3,(H,35,41)(H,37,42)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536596 (CHEMBL4534613) Show SMILES CCC(C)c1cc(C)c(CNC(=O)c2cc(cc3n(ncc23)C(C)C)-c2ccc(nc2)N2CCN(CC2)C(C)C)c(=O)[nH]1 Show InChI InChI=1S/C34H45N7O2/c1-8-23(6)30-15-24(7)28(34(43)38-30)19-36-33(42)27-16-26(17-31-29(27)20-37-41(31)22(4)5)25-9-10-32(35-18-25)40-13-11-39(12-14-40)21(2)3/h9-10,15-18,20-23H,8,11-14,19H2,1-7H3,(H,36,42)(H,38,43)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536600 (CHEMBL4584071) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(Br)cc2n(ncc12)C(C)C Show InChI InChI=1S/C21H25BrN4O2/c1-5-6-14-7-13(4)25-21(28)17(14)10-23-20(27)16-8-15(22)9-19-18(16)11-24-26(19)12(2)3/h7-9,11-12H,5-6,10H2,1-4H3,(H,23,27)(H,25,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536554 (CHEMBL4535507) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C(C)C)-c1ccccc1 Show InChI InChI=1S/C27H30N4O2/c1-5-9-20-12-18(4)30-27(33)23(20)15-28-26(32)22-13-21(19-10-7-6-8-11-19)14-25-24(22)16-29-31(25)17(2)3/h6-8,10-14,16-17H,5,9,15H2,1-4H3,(H,28,32)(H,30,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536583 (CHEMBL4533229) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C(C)C)N1CCCNCC1 Show InChI InChI=1S/C26H36N6O2/c1-5-7-19-12-18(4)30-26(34)22(19)15-28-25(33)21-13-20(31-10-6-8-27-9-11-31)14-24-23(21)16-29-32(24)17(2)3/h12-14,16-17,27H,5-11,15H2,1-4H3,(H,28,33)(H,30,34)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536592 (CHEMBL4554500) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C(C)C)-c1ccc(F)cc1 Show InChI InChI=1S/C27H29FN4O2/c1-5-6-19-11-17(4)31-27(34)23(19)14-29-26(33)22-12-20(18-7-9-21(28)10-8-18)13-25-24(22)15-30-32(25)16(2)3/h7-13,15-16H,5-6,14H2,1-4H3,(H,29,33)(H,31,34)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536575 (CHEMBL4521620) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(CC3CCC3)ncc12)-c1ccc(nc1)N1CCN(CC1)C(C)C Show InChI InChI=1S/C35H45N7O2/c1-5-7-26-16-24(4)39-35(44)30(26)20-37-34(43)29-17-28(18-32-31(29)21-38-42(32)22-25-8-6-9-25)27-10-11-33(36-19-27)41-14-12-40(13-15-41)23(2)3/h10-11,16-19,21,23,25H,5-9,12-15,20,22H2,1-4H3,(H,37,43)(H,39,44)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH1 (Homo sapiens (Human))	BDBM50536604 (CHEMBL4594174) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C(C)C)-c1ccc(nc1)N1CCNCC1 Show InChI InChI=1S/C30H37N7O2/c1-5-6-21-13-20(4)35-30(39)25(21)17-33-29(38)24-14-23(15-27-26(24)18-34-37(27)19(2)3)22-7-8-28(32-16-22)36-11-9-31-10-12-36/h7-8,13-16,18-19,31H,5-6,9-12,17H2,1-4H3,(H,33,38)(H,35,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH1 histone methyltransferase activity of EZH1/EED/SUZ12/RBBP4/AEBP2 protein complex (unknown origin) using histone H3 peptide as subs...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536599 (CHEMBL4520484) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C(C)C)-c1ccc(cn1)C(F)(F)F Show InChI InChI=1S/C27H28F3N5O2/c1-5-6-17-9-16(4)34-26(37)21(17)13-32-25(36)20-10-18(11-24-22(20)14-33-35(24)15(2)3)23-8-7-19(12-31-23)27(28,29)30/h7-12,14-15H,5-6,13H2,1-4H3,(H,32,36)(H,34,37)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536580 (CHEMBL4566302) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C(C)C)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C28H29F3N4O2/c1-5-6-19-11-17(4)34-27(37)23(19)14-32-26(36)22-12-20(13-25-24(22)15-33-35(25)16(2)3)18-7-9-21(10-8-18)28(29,30)31/h7-13,15-16H,5-6,14H2,1-4H3,(H,32,36)(H,34,37)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH1 (Homo sapiens (Human))	BDBM50075071 (CHEMBL3414619) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C(C)C)-c1ccc(nc1)N1CCN(CC1)C(C)C Show InChI InChI=1S/C33H43N7O2/c1-7-8-24-15-23(6)37-33(42)28(24)19-35-32(41)27-16-26(17-30-29(27)20-36-40(30)22(4)5)25-9-10-31(34-18-25)39-13-11-38(12-14-39)21(2)3/h9-10,15-18,20-22H,7-8,11-14,19H2,1-6H3,(H,35,41)(H,37,42)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH1 histone methyltransferase activity of EZH1/EED/SUZ12/RBBP4/AEBP2 protein complex (unknown origin) using histone H3 peptide as subs...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536605 (CHEMBL4483642) Show SMILES CCc1cc(C)c(CNC(=O)c2cc(cc3n(ncc23)C(C)C)-c2ccc(nc2)N2CCN(CC2)C(C)C)c(=O)[nH]1 Show InChI InChI=1S/C32H41N7O2/c1-7-25-14-22(6)27(32(41)36-25)18-34-31(40)26-15-24(16-29-28(26)19-35-39(29)21(4)5)23-8-9-30(33-17-23)38-12-10-37(11-13-38)20(2)3/h8-9,14-17,19-21H,7,10-13,18H2,1-6H3,(H,34,40)(H,36,41)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH1 (Homo sapiens (Human))	BDBM50536560 (CHEMBL4567859) Show SMILES CC(C)N1CCN(CC1)c1ccc(cn1)-c1cc(C(=O)NCc2c(cc(C)[nH]c2=O)C2CCCC2)c2cnn(C(C)C)c2c1 Show InChI InChI=1S/C35H45N7O2/c1-22(2)40-12-14-41(15-13-40)33-11-10-26(19-36-33)27-17-29(30-21-38-42(23(3)4)32(30)18-27)34(43)37-20-31-28(25-8-6-7-9-25)16-24(5)39-35(31)44/h10-11,16-19,21-23,25H,6-9,12-15,20H2,1-5H3,(H,37,43)(H,39,44)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH1 histone methyltransferase activity of EZH1/EED/SUZ12/RBBP4/AEBP2 protein complex (unknown origin) using histone H3 peptide as subs...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH1 (Homo sapiens (Human))	BDBM50536579 (CHEMBL4557033) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C(C)C)-c1ccc(nc1)N1CCN(CC)CC1 Show InChI InChI=1S/C32H41N7O2/c1-6-8-23-15-22(5)36-32(41)27(23)19-34-31(40)26-16-25(17-29-28(26)20-35-39(29)21(3)4)24-9-10-30(33-18-24)38-13-11-37(7-2)12-14-38/h9-10,15-18,20-21H,6-8,11-14,19H2,1-5H3,(H,34,40)(H,36,41)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH1 histone methyltransferase activity of EZH1/EED/SUZ12/RBBP4/AEBP2 protein complex (unknown origin) using histone H3 peptide as subs...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH1 (Homo sapiens (Human))	BDBM50536573 (CHEMBL4559875) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C1CCCC1)-c1ccc(nc1)N1CCN(CC1)C(C)C Show InChI InChI=1S/C35H45N7O2/c1-5-8-25-17-24(4)39-35(44)30(25)21-37-34(43)29-18-27(19-32-31(29)22-38-42(32)28-9-6-7-10-28)26-11-12-33(36-20-26)41-15-13-40(14-16-41)23(2)3/h11-12,17-20,22-23,28H,5-10,13-16,21H2,1-4H3,(H,37,43)(H,39,44)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	108	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH1 histone methyltransferase activity of EZH1/EED/SUZ12/RBBP4/AEBP2 protein complex (unknown origin) using histone H3 peptide as subs...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536559 (CHEMBL4535050) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C1CCCCCC1)-c1ccc(nc1)N1CCN(CC1)C(C)C Show InChI InChI=1S/C37H49N7O2/c1-5-10-27-19-26(4)41-37(46)32(27)23-39-36(45)31-20-29(21-34-33(31)24-40-44(34)30-11-8-6-7-9-12-30)28-13-14-35(38-22-28)43-17-15-42(16-18-43)25(2)3/h13-14,19-22,24-25,30H,5-12,15-18,23H2,1-4H3,(H,39,45)(H,41,46)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	117	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH1 (Homo sapiens (Human))	BDBM50536589 (CHEMBL4545986) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C(CC)CC)-c1ccc(nc1)N1CCN(CC1)C(C)C Show InChI InChI=1S/C35H47N7O2/c1-7-10-25-17-24(6)39-35(44)30(25)21-37-34(43)29-18-27(19-32-31(29)22-38-42(32)28(8-2)9-3)26-11-12-33(36-20-26)41-15-13-40(14-16-41)23(4)5/h11-12,17-20,22-23,28H,7-10,13-16,21H2,1-6H3,(H,37,43)(H,39,44)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH1 histone methyltransferase activity of EZH1/EED/SUZ12/RBBP4/AEBP2 protein complex (unknown origin) using histone H3 peptide as subs...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH1 (Homo sapiens (Human))	BDBM50536572 (CHEMBL4539055) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C(C)(C)C)-c1ccc(nc1)N1CCN(CC1)C(C)C Show InChI InChI=1S/C34H45N7O2/c1-8-9-24-16-23(4)38-33(43)28(24)20-36-32(42)27-17-26(18-30-29(27)21-37-41(30)34(5,6)7)25-10-11-31(35-19-25)40-14-12-39(13-15-40)22(2)3/h10-11,16-19,21-22H,8-9,12-15,20H2,1-7H3,(H,36,42)(H,38,43)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	127	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH1 histone methyltransferase activity of EZH1/EED/SUZ12/RBBP4/AEBP2 protein complex (unknown origin) using histone H3 peptide as subs...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536557 (CHEMBL4568471) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(CC3CCCC3)ncc12)-c1ccc(nc1)N1CCN(CC1)C(C)C Show InChI InChI=1S/C36H47N7O2/c1-5-8-27-17-25(4)40-36(45)31(27)21-38-35(44)30-18-29(19-33-32(30)22-39-43(33)23-26-9-6-7-10-26)28-11-12-34(37-20-28)42-15-13-41(14-16-42)24(2)3/h11-12,17-20,22,24,26H,5-10,13-16,21,23H2,1-4H3,(H,38,44)(H,40,45)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	149	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH1 (Homo sapiens (Human))	BDBM50536585 (CHEMBL4554286) Show SMILES CCCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C(C)C)-c1ccc(nc1)N1CCN(CC1)C(C)C Show InChI InChI=1S/C34H45N7O2/c1-7-8-9-25-16-24(6)38-34(43)29(25)20-36-33(42)28-17-27(18-31-30(28)21-37-41(31)23(4)5)26-10-11-32(35-19-26)40-14-12-39(13-15-40)22(2)3/h10-11,16-19,21-23H,7-9,12-15,20H2,1-6H3,(H,36,42)(H,38,43)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH1 histone methyltransferase activity of EZH1/EED/SUZ12/RBBP4/AEBP2 protein complex (unknown origin) using histone H3 peptide as subs...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536590 (CHEMBL4539350) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(C)ncc12)-c1ccc(nc1)N1CCN(CC1)C(C)C Show InChI InChI=1S/C31H39N7O2/c1-6-7-22-14-21(4)35-31(40)26(22)18-33-30(39)25-15-24(16-28-27(25)19-34-36(28)5)23-8-9-29(32-17-23)38-12-10-37(11-13-38)20(2)3/h8-9,14-17,19-20H,6-7,10-13,18H2,1-5H3,(H,33,39)(H,35,40)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH1 (Homo sapiens (Human))	BDBM50536598 (CHEMBL4551319) Show SMILES CC(C)Cc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C(C)C)-c1ccc(nc1)N1CCN(CC1)C(C)C Show InChI InChI=1S/C34H45N7O2/c1-21(2)14-27-15-24(7)38-34(43)29(27)19-36-33(42)28-16-26(17-31-30(28)20-37-41(31)23(5)6)25-8-9-32(35-18-25)40-12-10-39(11-13-40)22(3)4/h8-9,15-18,20-23H,10-14,19H2,1-7H3,(H,36,42)(H,38,43)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	211	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH1 histone methyltransferase activity of EZH1/EED/SUZ12/RBBP4/AEBP2 protein complex (unknown origin) using histone H3 peptide as subs...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536603 (CHEMBL4572342) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(Cc3ccccc3)ncc12)-c1ccc(nc1)N1CCN(CC1)C(C)C Show InChI InChI=1S/C37H43N7O2/c1-5-9-28-18-26(4)41-37(46)32(28)22-39-36(45)31-19-30(20-34-33(31)23-40-44(34)24-27-10-7-6-8-11-27)29-12-13-35(38-21-29)43-16-14-42(15-17-43)25(2)3/h6-8,10-13,18-21,23,25H,5,9,14-17,22,24H2,1-4H3,(H,39,45)(H,41,46)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH1 (Homo sapiens (Human))	BDBM50536574 (CHEMBL4521710) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C1CCCCC1)-c1ccc(nc1)N1CCN(CC1)C(C)C Show InChI InChI=1S/C36H47N7O2/c1-5-9-26-18-25(4)40-36(45)31(26)22-38-35(44)30-19-28(20-33-32(30)23-39-43(33)29-10-7-6-8-11-29)27-12-13-34(37-21-27)42-16-14-41(15-17-42)24(2)3/h12-13,18-21,23-24,29H,5-11,14-17,22H2,1-4H3,(H,38,44)(H,40,45)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	315	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH1 histone methyltransferase activity of EZH1/EED/SUZ12/RBBP4/AEBP2 protein complex (unknown origin) using histone H3 peptide as subs...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH1 (Homo sapiens (Human))	BDBM50536563 (CHEMBL4559801) Show SMILES CC(C)N1CCN(CC1)c1ccc(cn1)-c1cc(C(=O)NCc2c(cc(C)[nH]c2=O)C(C)C)c2cnn(C(C)C)c2c1 Show InChI InChI=1S/C33H43N7O2/c1-20(2)26-14-23(7)37-33(42)29(26)18-35-32(41)27-15-25(16-30-28(27)19-36-40(30)22(5)6)24-8-9-31(34-17-24)39-12-10-38(11-13-39)21(3)4/h8-9,14-17,19-22H,10-13,18H2,1-7H3,(H,35,41)(H,37,42)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH1 histone methyltransferase activity of EZH1/EED/SUZ12/RBBP4/AEBP2 protein complex (unknown origin) using histone H3 peptide as subs...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536553 (CHEMBL4525296) Show SMILES CC(C)N1CCN(CC1)c1ccc(cn1)-c1cc(C(=O)NCc2c(C)c(C)c(C)[nH]c2=O)c2cnn(C(C)C)c2c1 Show InChI InChI=1S/C32H41N7O2/c1-19(2)37-10-12-38(13-11-37)30-9-8-24(16-33-30)25-14-26(28-18-35-39(20(3)4)29(28)15-25)31(40)34-17-27-22(6)21(5)23(7)36-32(27)41/h8-9,14-16,18-20H,10-13,17H2,1-7H3,(H,34,40)(H,36,41)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	328	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536597 (CHEMBL4521009) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2nn(cc12)C(C)C)-c1ccc(nc1)N1CCN(CC1)C(C)C Show InChI InChI=1S/C33H43N7O2/c1-7-8-24-15-23(6)36-33(42)28(24)19-35-32(41)27-16-26(17-30-29(27)20-40(37-30)22(4)5)25-9-10-31(34-18-25)39-13-11-38(12-14-39)21(2)3/h9-10,15-18,20-22H,7-8,11-14,19H2,1-6H3,(H,35,41)(H,36,42)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	384	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH1 (Homo sapiens (Human))	BDBM50536578 (CHEMBL4529085) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(CCCCCCO)ncc12)-c1ccc(nc1)N1CCN(CC1)C(C)C Show InChI InChI=1S/C36H49N7O3/c1-5-10-27-19-26(4)40-36(46)31(27)23-38-35(45)30-20-29(21-33-32(30)24-39-43(33)13-8-6-7-9-18-44)28-11-12-34(37-22-28)42-16-14-41(15-17-42)25(2)3/h11-12,19-22,24-25,44H,5-10,13-18,23H2,1-4H3,(H,38,45)(H,40,46)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	394	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH1 histone methyltransferase activity of EZH1/EED/SUZ12/RBBP4/AEBP2 protein complex (unknown origin) using histone H3 peptide as subs...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50536558 (CHEMBL4521826) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(-c2ccc(nc2)N2CCN(CC2)C(C)C)c2cnn(C(C)C)c2c1 Show InChI InChI=1S/C33H43N7O2/c1-7-8-24-15-23(6)37-33(42)28(24)19-35-32(41)26-16-27(29-20-36-40(22(4)5)30(29)17-26)25-9-10-31(34-18-25)39-13-11-38(12-14-39)21(2)3/h9-10,15-18,20-22H,7-8,11-14,19H2,1-6H3,(H,35,41)(H,37,42)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH1 (Homo sapiens (Human))	BDBM50536593 (CHEMBL4569399) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C(C)C)C1CCNCC1 Show InChI InChI=1S/C26H35N5O2/c1-5-6-19-11-17(4)30-26(33)22(19)14-28-25(32)21-12-20(18-7-9-27-10-8-18)13-24-23(21)15-29-31(24)16(2)3/h11-13,15-16,18,27H,5-10,14H2,1-4H3,(H,28,32)(H,30,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	613	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH1 histone methyltransferase activity of EZH1/EED/SUZ12/RBBP4/AEBP2 protein complex (unknown origin) using histone H3 peptide as subs...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH1 (Homo sapiens (Human))	BDBM50536562 (CHEMBL4542135) Show SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2n(ncc12)C(C)C)-c1ccccn1 Show InChI InChI=1S/C26H29N5O2/c1-5-8-18-11-17(4)30-26(33)21(18)14-28-25(32)20-12-19(23-9-6-7-10-27-23)13-24-22(20)15-29-31(24)16(2)3/h6-7,9-13,15-16H,5,8,14H2,1-4H3,(H,28,32)(H,30,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	681	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of EZH1 histone methyltransferase activity of EZH1/EED/SUZ12/RBBP4/AEBP2 protein complex (unknown origin) using histone H3 peptide as subs...				J Med Chem 59: 7617-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00855 BindingDB Entry DOI: 10.7270/Q2JW8JC4
					More data for this Ligand-Target Pair

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