Found 20 hits Enz. Inhib. hit(s) with all data for entry = 50011312 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50511105
(GWP-42004 | Gwp42004 | O-4394 | THCV | Tetrahydroc...)Show SMILES [H][C@@]12C=C(C)CC[C@@]1([H])C(C)(C)Oc1cc(CCC)cc(O)c21 |r,t:2| Show InChI InChI=1S/C19H26O2/c1-5-6-13-10-16(20)18-14-9-12(2)7-8-15(14)19(3,4)21-17(18)11-13/h9-11,14-15,20H,5-8H2,1-4H3/t14-,15-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
PC cid
PC sid
PDB
UniChem
| Article
PubMed
| 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-CP-55,940 from recombinant human CB1R expressed in HEK293 cell membranes after 90 mins |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.9b00831
BindingDB Entry DOI: 10.7270/Q2639T9W |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50546337
(CHEMBL4747195)Show SMILES [H][C@@]12C=C(CO)CC[C@@]1([H])C(C)(C)Oc1cc(CCC)cc(O)c21 |r,t:2| | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-CP-55,940 from recombinant human CB1R expressed in HEK293 cell membranes after 90 mins |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.9b00831
BindingDB Entry DOI: 10.7270/Q2639T9W |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50511105
(GWP-42004 | Gwp42004 | O-4394 | THCV | Tetrahydroc...)Show SMILES [H][C@@]12C=C(C)CC[C@@]1([H])C(C)(C)Oc1cc(CCC)cc(O)c21 |r,t:2| Show InChI InChI=1S/C19H26O2/c1-5-6-13-10-16(20)18-14-9-12(2)7-8-15(14)19(3,4)21-17(18)11-13/h9-11,14-15,20H,5-8H2,1-4H3/t14-,15-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
PDB
UniChem
| Article
PubMed
| 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-CP-55,940 from recombinant human CB2R expressed in HEK293 cell membranes after 90 mins |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.9b00831
BindingDB Entry DOI: 10.7270/Q2639T9W |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50546337
(CHEMBL4747195)Show SMILES [H][C@@]12C=C(CO)CC[C@@]1([H])C(C)(C)Oc1cc(CCC)cc(O)c21 |r,t:2| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-CP-55,940 from recombinant human CB2R expressed in HEK293 cell membranes after 90 mins |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.9b00831
BindingDB Entry DOI: 10.7270/Q2639T9W |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50546338
(CHEMBL4760215)Show SMILES [H][C@@]12C=C(C)[C@@H](O)C[C@@]1([H])C(C)(C)Oc1cc(CCC)cc(O)c21 |r,t:2| | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-CP-55,940 from recombinant human CB1R expressed in HEK293 cell membranes after 90 mins |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.9b00831
BindingDB Entry DOI: 10.7270/Q2639T9W |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50546338
(CHEMBL4760215)Show SMILES [H][C@@]12C=C(C)[C@@H](O)C[C@@]1([H])C(C)(C)Oc1cc(CCC)cc(O)c21 |r,t:2| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 128 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-CP-55,940 from recombinant human CB2R expressed in HEK293 cell membranes after 90 mins |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.9b00831
BindingDB Entry DOI: 10.7270/Q2639T9W |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50546336
(CHEMBL4747880)Show SMILES [H][C@@]12CCC(=C[C@@]1([H])c1c(O)cc(CCC)cc1OC2(C)C)C(O)=O |r,c:4| | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| 187 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-CP-55,940 from recombinant human CB1R expressed in HEK293 cell membranes after 90 mins |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.9b00831
BindingDB Entry DOI: 10.7270/Q2639T9W |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50546336
(CHEMBL4747880)Show SMILES [H][C@@]12CCC(=C[C@@]1([H])c1c(O)cc(CCC)cc1OC2(C)C)C(O)=O |r,c:4| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| 590 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-CP-55,940 from recombinant human CB2R expressed in HEK293 cell membranes after 90 mins |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.9b00831
BindingDB Entry DOI: 10.7270/Q2639T9W |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50546339
(CHEMBL4763058)Show SMILES [H][C@@]12C=C(C)[C@H](O)C[C@@]1([H])C(C)(C)Oc1cc(CCC)cc(O)c21 |r,t:2| | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-CP-55,940 from recombinant human CB1R expressed in HEK293 cell membranes after 90 mins |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.9b00831
BindingDB Entry DOI: 10.7270/Q2639T9W |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50546339
(CHEMBL4763058)Show SMILES [H][C@@]12C=C(C)[C@H](O)C[C@@]1([H])C(C)(C)Oc1cc(CCC)cc(O)c21 |r,t:2| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-CP-55,940 from recombinant human CB2R expressed in HEK293 cell membranes after 90 mins |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.9b00831
BindingDB Entry DOI: 10.7270/Q2639T9W |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50511105
(GWP-42004 | Gwp42004 | O-4394 | THCV | Tetrahydroc...)Show SMILES [H][C@@]12C=C(C)CC[C@@]1([H])C(C)(C)Oc1cc(CCC)cc(O)c21 |r,t:2| Show InChI InChI=1S/C19H26O2/c1-5-6-13-10-16(20)18-14-9-12(2)7-8-15(14)19(3,4)21-17(18)11-13/h9-11,14-15,20H,5-8H2,1-4H3/t14-,15-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-CP-55,940 from recombinant human CB1R expressed in HEK293 cell membranes after 90 mins |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.9b00831
BindingDB Entry DOI: 10.7270/Q2639T9W |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50511105
(GWP-42004 | Gwp42004 | O-4394 | THCV | Tetrahydroc...)Show SMILES [H][C@@]12C=C(C)CC[C@@]1([H])C(C)(C)Oc1cc(CCC)cc(O)c21 |r,t:2| Show InChI InChI=1S/C19H26O2/c1-5-6-13-10-16(20)18-14-9-12(2)7-8-15(14)19(3,4)21-17(18)11-13/h9-11,14-15,20H,5-8H2,1-4H3/t14-,15-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-CP-55,940 from recombinant human CB2R expressed in HEK293 cell membranes after 90 mins |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.9b00831
BindingDB Entry DOI: 10.7270/Q2639T9W |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50546337
(CHEMBL4747195)Show SMILES [H][C@@]12C=C(CO)CC[C@@]1([H])C(C)(C)Oc1cc(CCC)cc(O)c21 |r,t:2| | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-CP-55,940 from recombinant human CB1R expressed in HEK293 cell membranes after 90 mins |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.9b00831
BindingDB Entry DOI: 10.7270/Q2639T9W |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50546337
(CHEMBL4747195)Show SMILES [H][C@@]12C=C(CO)CC[C@@]1([H])C(C)(C)Oc1cc(CCC)cc(O)c21 |r,t:2| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-CP-55,940 from recombinant human CB2R expressed in HEK293 cell membranes after 90 mins |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.9b00831
BindingDB Entry DOI: 10.7270/Q2639T9W |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50546338
(CHEMBL4760215)Show SMILES [H][C@@]12C=C(C)[C@@H](O)C[C@@]1([H])C(C)(C)Oc1cc(CCC)cc(O)c21 |r,t:2| | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-CP-55,940 from recombinant human CB1R expressed in HEK293 cell membranes after 90 mins |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.9b00831
BindingDB Entry DOI: 10.7270/Q2639T9W |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50546338
(CHEMBL4760215)Show SMILES [H][C@@]12C=C(C)[C@@H](O)C[C@@]1([H])C(C)(C)Oc1cc(CCC)cc(O)c21 |r,t:2| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 808 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-CP-55,940 from recombinant human CB2R expressed in HEK293 cell membranes after 90 mins |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.9b00831
BindingDB Entry DOI: 10.7270/Q2639T9W |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50546336
(CHEMBL4747880)Show SMILES [H][C@@]12CCC(=C[C@@]1([H])c1c(O)cc(CCC)cc1OC2(C)C)C(O)=O |r,c:4| | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-CP-55,940 from recombinant human CB1R expressed in HEK293 cell membranes after 90 mins |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.9b00831
BindingDB Entry DOI: 10.7270/Q2639T9W |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50546336
(CHEMBL4747880)Show SMILES [H][C@@]12CCC(=C[C@@]1([H])c1c(O)cc(CCC)cc1OC2(C)C)C(O)=O |r,c:4| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-CP-55,940 from recombinant human CB2R expressed in HEK293 cell membranes after 90 mins |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.9b00831
BindingDB Entry DOI: 10.7270/Q2639T9W |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50546339
(CHEMBL4763058)Show SMILES [H][C@@]12C=C(C)[C@H](O)C[C@@]1([H])C(C)(C)Oc1cc(CCC)cc(O)c21 |r,t:2| | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-CP-55,940 from recombinant human CB1R expressed in HEK293 cell membranes after 90 mins |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.9b00831
BindingDB Entry DOI: 10.7270/Q2639T9W |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50546339
(CHEMBL4763058)Show SMILES [H][C@@]12C=C(C)[C@H](O)C[C@@]1([H])C(C)(C)Oc1cc(CCC)cc(O)c21 |r,t:2| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-CP-55,940 from recombinant human CB2R expressed in HEK293 cell membranes after 90 mins |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.9b00831
BindingDB Entry DOI: 10.7270/Q2639T9W |
More data for this
Ligand-Target Pair | |
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