Compile Data Set for Download or QSAR

Found 8 hits Enz. Inhib. hit(s) with all data for entry = 50011359   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human))	BDBM50546508 (CHEMBL4746230) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\c1nc(cs1)-c1c2-[#8]-[#6]3=[#6]-[#6](-[#8])=[#6](-[#6](-[#6])=O)-[#6](=O)[C@]3([#6])c2c(-[#8])c(-[#6])c1-[#8] |r,t:18,21| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant TDP1 (unknown origin) expressed in Escherichia coli using 5'-FAM/3'-BHQ1 tagged oligonucleotide as substrate by fluorescenc...				Citation and Details Article DOI: 10.1021/acs.jnatprod.9b01089 BindingDB Entry DOI: 10.7270/Q29S1VNK
					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human))	BDBM50546509 (CHEMBL4760174) Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-c1nc(cs1)-c1c2-[#8]-[#6]3=[#6]-[#6](-[#8])=[#6](-[#6](-[#6])=O)-[#6](=O)[C@]3([#6])c2c(-[#8])c(-[#6])c1-[#8] |r,t:18,21| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant TDP1 (unknown origin) expressed in Escherichia coli using 5'-FAM/3'-BHQ1 tagged oligonucleotide as substrate by fluorescenc...				Citation and Details Article DOI: 10.1021/acs.jnatprod.9b01089 BindingDB Entry DOI: 10.7270/Q29S1VNK
					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human))	BDBM50546512 (CHEMBL4799682) Show SMILES CC(=C)[C@@H]1CCC(\C=N/Nc2nc(cs2)-c2c3OC4=CC(O)=C(C(C)=O)C(=O)[C@]4(C)c3c(O)c(C)c2O)=CC1 |r,c:40,t:19,22| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant TDP1 (unknown origin) expressed in Escherichia coli using 5'-FAM/3'-BHQ1 tagged oligonucleotide as substrate by fluorescenc...				Citation and Details Article DOI: 10.1021/acs.jnatprod.9b01089 BindingDB Entry DOI: 10.7270/Q29S1VNK
					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human))	BDBM50546515 (CHEMBL4756604) Show SMILES [H][C@@]12CC[C@@](C)(\C(C1)=N/Nc1nc(cs1)-c1c3OC4=CC(O)=C(C(C)=O)C(=O)[C@]4(C)c3c(O)c(C)c1O)C2(C)C |r,t:20,23| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant TDP1 (unknown origin) expressed in Escherichia coli using 5'-FAM/3'-BHQ1 tagged oligonucleotide as substrate by fluorescenc...				Citation and Details Article DOI: 10.1021/acs.jnatprod.9b01089 BindingDB Entry DOI: 10.7270/Q29S1VNK
					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human))	BDBM50546513 (CHEMBL4761724) Show SMILES [H][C@@]12C[C@@]([H])(C=C(C1)\C=N/Nc1nc(cs1)-c1c3OC4=CC(O)=C(C(C)=O)C(=O)[C@]4(C)c3c(O)c(C)c1O)C2(C)C |r,c:5,t:21,24| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant TDP1 (unknown origin) expressed in Escherichia coli using 5'-FAM/3'-BHQ1 tagged oligonucleotide as substrate by fluorescenc...				Citation and Details Article DOI: 10.1021/acs.jnatprod.9b01089 BindingDB Entry DOI: 10.7270/Q29S1VNK
					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human))	BDBM50546514 (CHEMBL4750455) Show SMILES [H][C@@]12C[C@@]([H])(C(C=C1C)=NNc1nc(cs1)-c1c3OC4=CC(O)=C(C(C)=O)C(=O)[C@]4(C)c3c(O)c(C)c1O)C2(C)C |r,c:6,t:21,24| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant TDP1 (unknown origin) expressed in Escherichia coli using 5'-FAM/3'-BHQ1 tagged oligonucleotide as substrate by fluorescenc...				Citation and Details Article DOI: 10.1021/acs.jnatprod.9b01089 BindingDB Entry DOI: 10.7270/Q29S1VNK
					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human))	BDBM50546511 (CHEMBL4745693) Show SMILES CCCCCCc1nc(cs1)-c1c2OC3=CC(O)=C(C(C)=O)C(=O)[C@]3(C)c2c(O)c(C)c1O |r,t:15,18| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant TDP1 (unknown origin) expressed in Escherichia coli using 5'-FAM/3'-BHQ1 tagged oligonucleotide as substrate by fluorescenc...				Citation and Details Article DOI: 10.1021/acs.jnatprod.9b01089 BindingDB Entry DOI: 10.7270/Q29S1VNK
					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human))	BDBM50546510 (CHEMBL4797909) Show SMILES CC(CCCC(C)(C)O)Cc1nc(cs1)-c1c2OC3=CC(O)=C(C(C)=O)C(=O)[C@]3(C)c2c(O)c(C)c1O |r,t:19,22| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	139	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant TDP1 (unknown origin) expressed in Escherichia coli using 5'-FAM/3'-BHQ1 tagged oligonucleotide as substrate by fluorescenc...				Citation and Details Article DOI: 10.1021/acs.jnatprod.9b01089 BindingDB Entry DOI: 10.7270/Q29S1VNK
					More data for this Ligand-Target Pair