Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50550223![]() (CHEMBL4794300) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PubMed | n/a | n/a | 0.390 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at alphaLbeta2 in human Jurkat E6.1 cells assessed as reduction in cell adhesion to ICAM1 pre-incubated for 30 mins before ICAM1 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-5/beta-1 (Homo sapiens (Human)) | BDBM50439683![]() (CHEMBL2418221) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.670 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at alpha5beta1 in human K562 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fibrone... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50074661![]() ((S)-1-{(S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.840 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at alphaLbeta2 in human Jurkat E6.1 cells assessed as reduction in cell adhesion to ICAM1 pre-incubated for 30 mins before ICAM1 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-4/beta-1 (Homo sapiens (Human)) | BDBM50505781![]() (CHEMBL4461668) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibronectin binding to alpha4bbeta1 isolated from human Jurkat E6.1 cells incubated for 1 hr by scintillation-proximity assay based com... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50021394![]() (CHEMBL3289605) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibronectin binding to human recombinant alphaVbeta3 expressed in HEK293 cells incubated for 1 hr by scintillation-proximity assay base... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-4/beta-1 (Homo sapiens (Human)) | BDBM50505781![]() (CHEMBL4461668) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as reduction in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50237601![]() (CHEMBL411941 | CycloRGDfV | [(2S,5R,8S,11S)-5-Benz...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibronectin binding to human recombinant alphaVbeta3 expressed in HEK293 cells incubated for 1 hr by scintillation-proximity assay base... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50505779![]() (CHEMBL4461771) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem | PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibronectin binding to human recombinant alphaVbeta3 expressed in HEK293 cells incubated for 1 hr by scintillation-proximity assay base... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-5 (Homo sapiens (Human)) | BDBM50505779![]() (CHEMBL4461771) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem | PubMed | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibrinogen binding to alphaVbeta5 isolated form human mCf7 cells incubated for 1 hr by scintillation-proximity assay based competitive ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-5 (Homo sapiens (Human)) | BDBM50021393![]() (CHEMBL3289604) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibrinogen binding to alphaVbeta5 isolated form human mCf7 cells incubated for 1 hr by scintillation-proximity assay based competitive ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-5/beta-1 (Homo sapiens (Human)) | BDBM50021393![]() (CHEMBL3289604) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibronectin binding to alpha5beta1 isolated from human K562 cells incubated for 1 hr by scintillation-proximity assay based competitive... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-5/beta-1 (Homo sapiens (Human)) | BDBM50550224![]() (CHEMBL4797755) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PubMed | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibronectin binding to alpha5beta1 isolated from human K562 cells incubated for 1 hr by scintillation-proximity assay based competitive... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50021393![]() (CHEMBL3289604) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibronectin binding to human recombinant alphaVbeta3 expressed in HEK293 cells incubated for 1 hr by scintillation-proximity assay base... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50004058![]() ((2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-yl...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB PubMed | n/a | n/a | 7.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibrinogen binding to alpha2bbeta3 isolated from human HEL cells incubated for 1 hr by scintillation-proximity assay based competitive ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Integrin alpha-4/beta-1 (Homo sapiens (Human)) | BDBM50550222![]() (CHEMBL4777693) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PubMed | n/a | n/a | 7.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibronectin binding to alpha4bbeta1 isolated from human Jurkat E6.1 cells incubated for 1 hr by scintillation-proximity assay based com... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-4/beta-1 (Homo sapiens (Human)) | BDBM50074661![]() ((S)-1-{(S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 8.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as reduction in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-4/beta-1 (Homo sapiens (Human)) | BDBM50550222![]() (CHEMBL4777693) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PubMed | n/a | n/a | 8.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as reduction in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50004058![]() ((2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-yl...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB PubMed | n/a | n/a | 9.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at alpha2bbeta3 in human HEL cells assessed as reduction in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinog... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Integrin alpha-5/beta-1 (Homo sapiens (Human)) | BDBM50550223![]() (CHEMBL4794300) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PubMed | n/a | n/a | 9.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibronectin binding to alpha5beta1 isolated from human K562 cells incubated for 1 hr by scintillation-proximity assay based competitive... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-4/beta-1 (Homo sapiens (Human)) | BDBM50505772![]() (CHEMBL4589062) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | PubMed | n/a | n/a | 9.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibronectin binding to alpha4bbeta1 isolated from human Jurkat E6.1 cells incubated for 1 hr by scintillation-proximity assay based com... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50550223![]() (CHEMBL4794300) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PubMed | n/a | n/a | 9.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibronectin binding to human recombinant alphaVbeta3 expressed in HEK293 cells incubated for 1 hr by scintillation-proximity assay base... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-4/beta-1 (Homo sapiens (Human)) | BDBM50550225![]() (CHEMBL4764510) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibronectin binding to alpha4bbeta1 isolated from human Jurkat E6.1 cells incubated for 1 hr by scintillation-proximity assay based com... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-5 (Homo sapiens (Human)) | BDBM50237601![]() (CHEMBL411941 | CycloRGDfV | [(2S,5R,8S,11S)-5-Benz...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibrinogen binding to alphaVbeta5 isolated form human mCf7 cells incubated for 1 hr by scintillation-proximity assay based competitive ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-5 (Homo sapiens (Human)) | BDBM50237601![]() (CHEMBL411941 | CycloRGDfV | [(2S,5R,8S,11S)-5-Benz...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at alphaVbeta5 in human MCF7 cells assessed as reduction in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinog... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-4/beta-1 (Homo sapiens (Human)) | BDBM50550225![]() (CHEMBL4764510) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as reduction in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-6 (Homo sapiens (Human)) | BDBM50550225![]() (CHEMBL4764510) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibronectin binding to alphaVbeta6 isolated form human HT-29 cells incubated for 1 hr by scintillation-proximity assay based competitiv... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50222360![]() (Ac-Asp-Arg-Leu-Asp-Ser-OH | CHEMBL238484) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at alphaVbeta3 in human SK-MEL-24 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fi... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-5 (Homo sapiens (Human)) | BDBM50439683![]() (CHEMBL2418221) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at alphaVbeta5 in human MCF7 cells assessed as reduction in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinog... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-5/beta-1 (Homo sapiens (Human)) | BDBM50550225![]() (CHEMBL4764510) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibronectin binding to alpha5beta1 isolated from human K562 cells incubated for 1 hr by scintillation-proximity assay based competitive... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50505779![]() (CHEMBL4461771) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem | PubMed | n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at alphaVbeta3 in human SK-MEL-24 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fi... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-6 (Homo sapiens (Human)) | BDBM50550225![]() (CHEMBL4764510) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PubMed | n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at alphaVbeta6 in human HT-29 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fibron... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-5/beta-1 (Homo sapiens (Human)) | BDBM50505782![]() (CHEMBL4586928) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PubMed | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibronectin binding to alpha5beta1 isolated from human K562 cells incubated for 1 hr by scintillation-proximity assay based competitive... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50550223![]() (CHEMBL4794300) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PubMed | n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at alphaVbeta3 in human SK-MEL-24 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fi... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-6 (Homo sapiens (Human)) | BDBM50021393![]() (CHEMBL3289604) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 81 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibronectin binding to alphaVbeta6 isolated form human HT-29 cells incubated for 1 hr by scintillation-proximity assay based competitiv... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-5 (Homo sapiens (Human)) | BDBM50021394![]() (CHEMBL3289605) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 104 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibrinogen binding to alphaVbeta5 isolated form human mCf7 cells incubated for 1 hr by scintillation-proximity assay based competitive ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-5/beta-1 (Homo sapiens (Human)) | BDBM50505781![]() (CHEMBL4461668) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PubMed | n/a | n/a | 114 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibronectin binding to alpha5beta1 isolated from human K562 cells incubated for 1 hr by scintillation-proximity assay based competitive... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50550225![]() (CHEMBL4764510) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PubMed | n/a | n/a | 116 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibronectin binding to human recombinant alphaVbeta3 expressed in HEK293 cells incubated for 1 hr by scintillation-proximity assay base... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50237601![]() (CHEMBL411941 | CycloRGDfV | [(2S,5R,8S,11S)-5-Benz...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 146 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at alphaVbeta3 in human SK-MEL-24 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fi... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-5/beta-1 (Homo sapiens (Human)) | BDBM50505781![]() (CHEMBL4461668) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PubMed | n/a | n/a | 158 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at alpha5beta1 in human K562 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fibrone... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50505779![]() (CHEMBL4461771) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem | PubMed | n/a | n/a | 265 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibrinogen binding to alpha2bbeta3 isolated from human HEL cells incubated for 1 hr by scintillation-proximity assay based competitive ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50505781![]() (CHEMBL4461668) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PubMed | n/a | n/a | 285 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibronectin binding to human recombinant alphaVbeta3 expressed in HEK293 cells incubated for 1 hr by scintillation-proximity assay base... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-5/beta-1 (Homo sapiens (Human)) | BDBM50550222![]() (CHEMBL4777693) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PubMed | n/a | n/a | 331 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibronectin binding to alpha5beta1 isolated from human K562 cells incubated for 1 hr by scintillation-proximity assay based competitive... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50505781![]() (CHEMBL4461668) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PubMed | n/a | n/a | 352 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at alphaVbeta3 in human SK-MEL-24 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fi... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-5/beta-1 (Homo sapiens (Human)) | BDBM50550227![]() (CHEMBL4755971) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PubMed | n/a | n/a | 417 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at alpha5beta1 in human K562 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fibrone... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-4/beta-1 (Homo sapiens (Human)) | BDBM50550223![]() (CHEMBL4794300) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PubMed | n/a | n/a | 498 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibronectin binding to alpha4bbeta1 isolated from human Jurkat E6.1 cells incubated for 1 hr by scintillation-proximity assay based com... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-5/beta-1 (Homo sapiens (Human)) | BDBM50550222![]() (CHEMBL4777693) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PubMed | n/a | n/a | 525 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at alpha5beta1 in human K562 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fibrone... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-4/beta-1 (Homo sapiens (Human)) | BDBM50550223![]() (CHEMBL4794300) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PubMed | n/a | n/a | 574 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as reduction in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-5 (Homo sapiens (Human)) | BDBM50550225![]() (CHEMBL4764510) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | PubMed | n/a | n/a | 634 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibrinogen binding to alphaVbeta5 isolated form human mCf7 cells incubated for 1 hr by scintillation-proximity assay based competitive ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50439683![]() (CHEMBL2418221) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 926 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at alphaVbeta3 in human SK-MEL-24 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fi... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-5/beta-1 (Homo sapiens (Human)) | BDBM50505772![]() (CHEMBL4589062) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibronectin binding to alpha5beta1 isolated from human K562 cells incubated for 1 hr by scintillation-proximity assay based competitive... | Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK | |||||||||||
More data for this Ligand-Target Pair |
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