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Target
Sequence
Name
&
Ki
IC50
Kd
EC50
Rate constants
ΔG°
ΔH°
-TΔS°
pH (Enzymatic Assay)
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Ki
IC50
Kd
EC50
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Compile Data Set for Download or QSAR
Found
30
hits Enz. Inhib. hit(s) with all data for entry = 50012174
Target/Host
(Institution)
Ligand
Target/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
k
off
s
-1
k
on
M
-1
s
-1
pH
Temp
°C
Macrophage metalloelastase
(Homo sapiens (Human))
BDBM50555050
(CHEMBL4764575)
Show SMILES
CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1Cc2ccc(OCCC[C@@H]([C@@H](CC(C)C)C(=O)N1)C(=O)NO)cc2 |r|
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
1
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP12 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
Macrophage metalloelastase
(Homo sapiens (Human))
BDBM50555052
(CHEMBL4751015)
Show SMILES
CC(C)C[C@@H]1[C@H](CCCOc2ccc(C[C@H](NC1=O)C(O)=O)cc2)C(=O)NO |r|
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
1.10
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP12 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
Macrophage metalloelastase
(Homo sapiens (Human))
BDBM50555051
(CHEMBL4739996)
Show SMILES
CC(C)C[C@@H]1[C@H](CCCOc2ccc(C[C@H](NC1=O)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cc2)C(=O)NO |r|
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
1.20
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP12 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
72 kDa type IV collagenase
(Homo sapiens (Human))
BDBM50555050
(CHEMBL4764575)
Show SMILES
CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1Cc2ccc(OCCC[C@@H]([C@@H](CC(C)C)C(=O)N1)C(=O)NO)cc2 |r|
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
5.80
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP2 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
Macrophage metalloelastase
(Homo sapiens (Human))
BDBM50555048
(CHEMBL4793938)
Show SMILES
CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(O)=O)C(=O)NCCNC(=O)c1ccc(NN)nc1 |r|
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
7.5
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP12 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
Macrophage metalloelastase
(Homo sapiens (Human))
BDBM50555047
(CHEMBL4794902)
Show SMILES
CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccc(OCCNC(=O)c2ccc(NN)nc2)cc1)C(O)=O |r|
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
8.90
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP12 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
Macrophage metalloelastase
(Homo sapiens (Human))
BDBM50555049
(CHEMBL4747528)
Show SMILES
CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(O)=O |r|
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
12
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP12 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
Matrilysin
(Homo sapiens (Human))
BDBM50555051
(CHEMBL4739996)
Show SMILES
CC(C)C[C@@H]1[C@H](CCCOc2ccc(C[C@H](NC1=O)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cc2)C(=O)NO |r|
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
15
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP7 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
Collagenase 3
(Homo sapiens (Human))
BDBM50555050
(CHEMBL4764575)
Show SMILES
CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1Cc2ccc(OCCC[C@@H]([C@@H](CC(C)C)C(=O)N1)C(=O)NO)cc2 |r|
Show InChI
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
15
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP13 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
Matrilysin
(Homo sapiens (Human))
BDBM50555050
(CHEMBL4764575)
Show SMILES
CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1Cc2ccc(OCCC[C@@H]([C@@H](CC(C)C)C(=O)N1)C(=O)NO)cc2 |r|
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
17
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP7 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9
(Homo sapiens (Human))
BDBM50555050
(CHEMBL4764575)
Show SMILES
CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1Cc2ccc(OCCC[C@@H]([C@@H](CC(C)C)C(=O)N1)C(=O)NO)cc2 |r|
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
20
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP9 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
Collagenase 3
(Homo sapiens (Human))
BDBM50555052
(CHEMBL4751015)
Show SMILES
CC(C)C[C@@H]1[C@H](CCCOc2ccc(C[C@H](NC1=O)C(O)=O)cc2)C(=O)NO |r|
Show InChI
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
31
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP13 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
Matrilysin
(Homo sapiens (Human))
BDBM50555052
(CHEMBL4751015)
Show SMILES
CC(C)C[C@@H]1[C@H](CCCOc2ccc(C[C@H](NC1=O)C(O)=O)cc2)C(=O)NO |r|
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
39
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP7 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
Collagenase 3
(Homo sapiens (Human))
BDBM50555048
(CHEMBL4793938)
Show SMILES
CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(O)=O)C(=O)NCCNC(=O)c1ccc(NN)nc1 |r|
Show InChI
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
78
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP13 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
Collagenase 3
(Homo sapiens (Human))
BDBM50555049
(CHEMBL4747528)
Show SMILES
CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(O)=O |r|
Show InChI
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
81
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP13 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
Collagenase 3
(Homo sapiens (Human))
BDBM50555051
(CHEMBL4739996)
Show SMILES
CC(C)C[C@@H]1[C@H](CCCOc2ccc(C[C@H](NC1=O)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cc2)C(=O)NO |r|
Show InChI
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
89
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP13 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9
(Homo sapiens (Human))
BDBM50555049
(CHEMBL4747528)
Show SMILES
CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(O)=O |r|
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
125
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP9 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9
(Homo sapiens (Human))
BDBM50555047
(CHEMBL4794902)
Show SMILES
CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccc(OCCNC(=O)c2ccc(NN)nc2)cc1)C(O)=O |r|
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
155
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP9 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
72 kDa type IV collagenase
(Homo sapiens (Human))
BDBM50555049
(CHEMBL4747528)
Show SMILES
CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(O)=O |r|
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
164
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP2 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
72 kDa type IV collagenase
(Homo sapiens (Human))
BDBM50555048
(CHEMBL4793938)
Show SMILES
CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(O)=O)C(=O)NCCNC(=O)c1ccc(NN)nc1 |r|
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
222
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP2 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
72 kDa type IV collagenase
(Homo sapiens (Human))
BDBM50555052
(CHEMBL4751015)
Show SMILES
CC(C)C[C@@H]1[C@H](CCCOc2ccc(C[C@H](NC1=O)C(O)=O)cc2)C(=O)NO |r|
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
300
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP2 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
Matrilysin
(Homo sapiens (Human))
BDBM50555049
(CHEMBL4747528)
Show SMILES
CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(O)=O |r|
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
323
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP7 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
72 kDa type IV collagenase
(Homo sapiens (Human))
BDBM50555051
(CHEMBL4739996)
Show SMILES
CC(C)C[C@@H]1[C@H](CCCOc2ccc(C[C@H](NC1=O)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cc2)C(=O)NO |r|
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
396
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP2 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
Matrilysin
(Homo sapiens (Human))
BDBM50555048
(CHEMBL4793938)
Show SMILES
CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(O)=O)C(=O)NCCNC(=O)c1ccc(NN)nc1 |r|
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
615
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP7 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9
(Homo sapiens (Human))
BDBM50555052
(CHEMBL4751015)
Show SMILES
CC(C)C[C@@H]1[C@H](CCCOc2ccc(C[C@H](NC1=O)C(O)=O)cc2)C(=O)NO |r|
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
1.10E+3
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP9 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9
(Homo sapiens (Human))
BDBM50555048
(CHEMBL4793938)
Show SMILES
CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(O)=O)C(=O)NCCNC(=O)c1ccc(NN)nc1 |r|
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
1.31E+3
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP9 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9
(Homo sapiens (Human))
BDBM50555051
(CHEMBL4739996)
Show SMILES
CC(C)C[C@@H]1[C@H](CCCOc2ccc(C[C@H](NC1=O)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cc2)C(=O)NO |r|
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
2.11E+3
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP9 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
72 kDa type IV collagenase
(Homo sapiens (Human))
BDBM50555047
(CHEMBL4794902)
Show SMILES
CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccc(OCCNC(=O)c2ccc(NN)nc2)cc1)C(O)=O |r|
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
>5.00E+3
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP2 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
Collagenase 3
(Homo sapiens (Human))
BDBM50555047
(CHEMBL4794902)
Show SMILES
CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccc(OCCNC(=O)c2ccc(NN)nc2)cc1)C(O)=O |r|
Show InChI
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
>5.00E+3
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP13 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair
Matrilysin
(Homo sapiens (Human))
BDBM50555047
(CHEMBL4794902)
Show SMILES
CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccc(OCCNC(=O)c2ccc(NN)nc2)cc1)C(O)=O |r|
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
>5.00E+3
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human recombinant MMP7 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometry
Citation and Details
Article DOI:
10.1021/acs.jmedchem.0c01514
BindingDB Entry DOI:
10.7270/Q2PC361P
More data for this
Ligand-Target Pair