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Target
Sequence
Name
&
Ki
IC50
Kd
EC50
Rate constants
ΔG°
ΔH°
-TΔS°
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/
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Compile Data Set for Download or QSAR
Found
135
hits Enz. Inhib. hit(s) with all data for entry = 50012541
Target/Host
(Institution)
Ligand
Target/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
k
off
s
-1
k
on
M
-1
s
-1
pH
Temp
°C
Probable G-protein coupled receptor 142
(Homo sapiens (Human))
BDBM50558172
(CHEMBL4750179)
Show SMILES
Cc1cc(ccn1)-c1ccc2OCCn3c(Nc4cccc(Cl)c4)nnc3-c2c1
Show InChI
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
37
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Homo sapiens (Human))
BDBM50558167
(CHEMBL4798957)
Show SMILES
Cc1cc(ccn1)-c1ccc2OCCn3c(Nc4cccc(OC(F)(F)F)c4)nnc3-c2c1
Show InChI
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
45
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Homo sapiens (Human))
BDBM50558171
(CHEMBL4790150)
Show SMILES
FC(F)(F)c1cccc(Nc2nnc3-c4cc(ccc4OCCn23)-c2ccncc2)c1
Show InChI
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
48
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Homo sapiens (Human))
BDBM50558161
(CHEMBL4746135)
Show SMILES
Cc1cc(ccn1)-c1ccc2OCCn3c(Oc4cccc(Cl)c4F)nnc3-c2c1
Show InChI
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
56
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Homo sapiens (Human))
BDBM50558165
(CHEMBL4761139)
Show SMILES
Cc1cc(ccn1)-c1ccc2OCCn3c(Oc4cccc(Cl)c4)nnc3-c2c1
Show InChI
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
58
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Mus musculus)
BDBM50558195
(CHEMBL4800653)
Show SMILES
Fc1c(Cl)cccc1NC(=O)N1CCOc2ccc(cc2C1)-c1ccncc1
Show InChI
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
59
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at mouse GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Mus musculus)
BDBM50558200
(CHEMBL4785678)
Show SMILES
O=C(Nc1cccc(c1)-c1ccccc1)N1CCOc2ccc(cc2C1)-c1ccncc1
Show InChI
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
62
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at mouse GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Homo sapiens (Human))
BDBM50558168
(CHEMBL4755454)
Show SMILES
FC(F)(F)Oc1cccc(Nc2nnc3-c4cc(ccc4OCCn23)-c2ccncc2)c1
Show InChI
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
63
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Homo sapiens (Human))
BDBM50558170
(CHEMBL4788072)
Show SMILES
Cc1cc(ccn1)-c1ccc2OCCn3c(Nc4cccc(c4)C(F)(F)F)nnc3-c2c1
Show InChI
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
63
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Homo sapiens (Human))
BDBM50558169
(CHEMBL4752684)
Show SMILES
CCc1cc(ccn1)-c1ccc2OCCn3c(Nc4cccc(c4)C(F)(F)F)nnc3-c2c1
Show InChI
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
74
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Homo sapiens (Human))
BDBM50558164
(CHEMBL4751613)
Show SMILES
Cc1cc(ccn1)-c1ccc2OCCn3c(Oc4cccc(OC(F)(F)F)c4)nnc3-c2c1
Show InChI
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
78
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Mus musculus)
BDBM50558199
(CHEMBL4763234)
Show SMILES
O=C(Nc1cccc(c1)C#N)N1CCOc2ccc(cc2C1)-c1ccncc1
Show InChI
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
79
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at mouse GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Homo sapiens (Human))
BDBM50558199
(CHEMBL4763234)
Show SMILES
O=C(Nc1cccc(c1)C#N)N1CCOc2ccc(cc2C1)-c1ccncc1
Show InChI
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
80
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Homo sapiens (Human))
BDBM50558163
(CHEMBL4743615)
Show SMILES
Cc1cc(ccn1)-c1ccc2OCCn3c(Oc4ccccc4OC(F)(F)F)nnc3-c2c1
Show InChI
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
89
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Mus musculus)
BDBM50558206
(CHEMBL4760456)
Show SMILES
COc1ccccc1NC(=O)N1CCOc2ccc(cc2C1)-c1ccncc1
Show InChI
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
92
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at mouse GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Homo sapiens (Human))
BDBM50558162
(CHEMBL4759692)
Show SMILES
Cc1cc(ccn1)-c1ccc2OCCn3c(Oc4ccccc4Cl)nnc3-c2c1
Show InChI
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
102
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Homo sapiens (Human))
BDBM50558174
(CHEMBL4787638)
Show SMILES
Clc1cccc(NC(=O)N2CCOc3ccc(cc3C2)-c2ccncc2)c1
Show InChI
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
108
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Mus musculus)
BDBM50558198
(CHEMBL4756319)
Show SMILES
FC(F)(F)c1cccc(NC(=O)N2CCOc3ccc(cc3C2)-c2ccncc2)c1
Show InChI
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
110
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at mouse GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Homo sapiens (Human))
BDBM50558177
(CHEMBL4783052)
Show SMILES
O=C(Nc1cccc(c1)C#N)N1CCOc2ccc(cc2C1)-n1ccnc1
Show InChI
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
110
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Homo sapiens (Human))
BDBM50558193
(CHEMBL4753373)
Show SMILES
Fc1ccc(NC(=O)N2CCOc3ccc(cc3C2)-c2ccncc2)cc1Cl
Show InChI
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
132
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Mus musculus)
BDBM50558173
(CHEMBL4755668)
Show SMILES
Clc1ccc(NC(=O)N2CCOc3ccc(cc3C2)-c2ccncc2)cc1Cl
Show InChI
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
138
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at mouse GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Homo sapiens (Human))
BDBM50558173
(CHEMBL4755668)
Show SMILES
Clc1ccc(NC(=O)N2CCOc3ccc(cc3C2)-c2ccncc2)cc1Cl
Show InChI
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
140
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Mus musculus)
BDBM50558197
(CHEMBL4756931)
Show SMILES
O=C(Nc1cccc(Oc2ccccc2)c1)N1CCOc2ccc(cc2C1)-c1ccncc1
Show InChI
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
146
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at mouse GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Homo sapiens (Human))
BDBM50558190
(CHEMBL4782723)
Show SMILES
Clc1ccc(NC(=O)N2CCNc3ccc(cc3C2)-c2ccncc2)cc1Cl
Show InChI
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
146
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Mus musculus)
BDBM50558194
(CHEMBL4754434)
Show SMILES
Clc1cccc(NC(=O)N2CCOc3ccc(cc3C2)-c2ccncc2)c1Cl
Show InChI
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
157
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at mouse GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Mus musculus)
BDBM50558191
(CHEMBL4751751)
Show SMILES
FC(F)(F)c1cccc(CS(=O)(=O)N2CCOc3ccc(cc3C2)-c2ccncc2)c1
Show InChI
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
157
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at mouse GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Homo sapiens (Human))
BDBM50558198
(CHEMBL4756319)
Show SMILES
FC(F)(F)c1cccc(NC(=O)N2CCOc3ccc(cc3C2)-c2ccncc2)c1
Show InChI
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
158
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Mus musculus)
BDBM50558190
(CHEMBL4782723)
Show SMILES
Clc1ccc(NC(=O)N2CCNc3ccc(cc3C2)-c2ccncc2)cc1Cl
Show InChI
KEGG
UniProtKB/SwissProt
GoogleScholar
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UniChem
Article
PubMed
n/a
n/a
158
n/a
n/a
n/a
n/a
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TBA
Assay Description
Agonist activity at mouse GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Homo sapiens (Human))
BDBM50558195
(CHEMBL4800653)
Show SMILES
Fc1c(Cl)cccc1NC(=O)N1CCOc2ccc(cc2C1)-c1ccncc1
Show InChI
KEGG
UniProtKB/SwissProt
antibodypedia
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UniChem
Article
PubMed
n/a
n/a
163
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Mus musculus)
BDBM50558174
(CHEMBL4787638)
Show SMILES
Clc1cccc(NC(=O)N2CCOc3ccc(cc3C2)-c2ccncc2)c1
Show InChI
KEGG
UniProtKB/SwissProt
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UniChem
Article
PubMed
n/a
n/a
164
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at mouse GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Homo sapiens (Human))
BDBM50558178
(CHEMBL4750165)
Show SMILES
COc1cccc(NC(=O)N2CCOc3ccc(cc3C2)-c2ccncc2OC)c1
Show InChI
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
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PC sid
UniChem
Article
PubMed
n/a
n/a
187
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Mus musculus)
BDBM50558176
(CHEMBL4779679)
Show SMILES
COc1cccc(NC(=O)N2CCOc3ccc(cc3C2)-c2ccnc3ccccc23)c1
Show InChI
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
216
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at mouse GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Homo sapiens (Human))
BDBM50558201
(CHEMBL4792959)
Show SMILES
Fc1cccc(NC(=O)N2CCOc3ccc(cc3C2)-c2ccncc2)c1
Show InChI
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
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PC sid
UniChem
Article
PubMed
n/a
n/a
224
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
BDBM50558167
(CHEMBL4798957)
Show SMILES
Cc1cc(ccn1)-c1ccc2OCCn3c(Nc4cccc(OC(F)(F)F)c4)nnc3-c2c1
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
236
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human ERG expressed in HEK293 cells assessed as reduction in S35-MK-0499 binding
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Homo sapiens (Human))
BDBM50558202
(CHEMBL4750832)
Show SMILES
COc1cccc(NC(=O)N2CCOc3ccc(cc3C2)-c2ccncc2)c1
Show InChI
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
249
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Mus musculus)
BDBM50558202
(CHEMBL4750832)
Show SMILES
COc1cccc(NC(=O)N2CCOc3ccc(cc3C2)-c2ccncc2)c1
Show InChI
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
305
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at mouse GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Cytochrome P450 2D6
(Homo sapiens (Human))
BDBM50558170
(CHEMBL4788072)
Show SMILES
Cc1cc(ccn1)-c1ccc2OCCn3c(Nc4cccc(c4)C(F)(F)F)nnc3-c2c1
Show InChI
PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
326
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human liver microsomes CYP2D6 using dextromethorphan as substrate by MUX-MS/MS analysis
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
BDBM50558169
(CHEMBL4752684)
Show SMILES
CCc1cc(ccn1)-c1ccc2OCCn3c(Nc4cccc(c4)C(F)(F)F)nnc3-c2c1
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
334
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human ERG expressed in HEK293 cells assessed as reduction in S35-MK-0499 binding
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Homo sapiens (Human))
BDBM50558200
(CHEMBL4785678)
Show SMILES
O=C(Nc1cccc(c1)-c1ccccc1)N1CCOc2ccc(cc2C1)-c1ccncc1
Show InChI
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
343
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Homo sapiens (Human))
BDBM50558182
(CHEMBL4782047)
Show SMILES
COc1cccc(NC(=O)N2CCOc3ccc(cc3C2)-c2ccnc(C)c2)c1
Show InChI
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
374
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
BDBM50558170
(CHEMBL4788072)
Show SMILES
Cc1cc(ccn1)-c1ccc2OCCn3c(Nc4cccc(c4)C(F)(F)F)nnc3-c2c1
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
388
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human ERG expressed in HEK293 cells assessed as reduction in S35-MK-0499 binding
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Homo sapiens (Human))
BDBM50558179
(CHEMBL4790417)
Show SMILES
COc1cccc(NC(=O)N2CCOc3ccc(cc3C2)-c2ccncc2C)c1
Show InChI
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
394
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Mus musculus)
BDBM50558201
(CHEMBL4792959)
Show SMILES
Fc1cccc(NC(=O)N2CCOc3ccc(cc3C2)-c2ccncc2)c1
Show InChI
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
413
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at mouse GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
BDBM50558172
(CHEMBL4750179)
Show SMILES
Cc1cc(ccn1)-c1ccc2OCCn3c(Nc4cccc(Cl)c4)nnc3-c2c1
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
428
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human ERG expressed in HEK293 cells assessed as reduction in S35-MK-0499 binding
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Mus musculus)
BDBM50558180
(CHEMBL4781458)
Show SMILES
Nc1cc(ccn1)-c1ccc2OCCN(Cc2c1)C(=O)Nc1cccc(c1)C#N
Show InChI
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
448
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at mouse GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Mus musculus)
BDBM50558178
(CHEMBL4750165)
Show SMILES
COc1cccc(NC(=O)N2CCOc3ccc(cc3C2)-c2ccncc2OC)c1
Show InChI
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
486
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at mouse GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Cytochrome P450 3A4
(Homo sapiens (Human))
BDBM50558171
(CHEMBL4790150)
Show SMILES
FC(F)(F)c1cccc(Nc2nnc3-c4cc(ccc4OCCn23)-c2ccncc2)c1
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
516
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human liver microsomes CYP3A4 using testosterone as substrate by MUX-MS/MS analysis
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 142
(Homo sapiens (Human))
BDBM50558206
(CHEMBL4760456)
Show SMILES
COc1ccccc1NC(=O)N1CCOc2ccc(cc2C1)-c1ccncc1
Show InChI
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
517
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Cytochrome P450 2C9
(Homo sapiens (Human))
BDBM50558171
(CHEMBL4790150)
Show SMILES
FC(F)(F)c1cccc(Nc2nnc3-c4cc(ccc4OCCn23)-c2ccncc2)c1
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
531
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human liver microsomes CYP2C9 using diclofenac as substrate by MUX-MS/MS analysis
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
BDBM50558171
(CHEMBL4790150)
Show SMILES
FC(F)(F)c1cccc(Nc2nnc3-c4cc(ccc4OCCn23)-c2ccncc2)c1
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
557
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human ERG expressed in HEK293 cells assessed as reduction in S35-MK-0499 binding
Citation and Details
Article DOI:
10.1016/j.bmcl.2016.04.018
BindingDB Entry DOI:
10.7270/Q2HM5D44
More data for this
Ligand-Target Pair
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