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Compile Data Set for Download or QSAR

Found 51 hits Enz. Inhib. hit(s) with all data for entry = 50013811   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mucolipin-1


(Homo sapiens)
BDBM50569856
PNG
(CHEMBL4875551)
Show SMILES COc1ccccc1N1CCN(CC1)c1ccccc1NS(=O)(=O)c1ccccc1
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n/an/a 1.80E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML1deltaNC-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mi...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-2


(Homo sapiens)
BDBM50569843
PNG
(CHEMBL4856175)
Show SMILES COc1ccccc1N1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1 |r|
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n/an/a 2.30E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML2-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mins by F...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-1


(Homo sapiens)
BDBM50569847
PNG
(CHEMBL4847300)
Show SMILES COc1ccccc1N1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1cccs1 |r|
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n/an/a 2.30E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML1deltaNC-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mi...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-1


(Homo sapiens)
BDBM50569843
PNG
(CHEMBL4856175)
Show SMILES COc1ccccc1N1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1 |r|
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n/an/a 2.60E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML1deltaNC-YFP expressed in HEK293 cells stimulated with ML-SA1 for 200 secs followed by incubation for 200 secs with compound...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Mucolipin-1


(Homo sapiens)
BDBM50569843
PNG
(CHEMBL4856175)
Show SMILES COc1ccccc1N1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1 |r|
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n/an/a 3.10E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML1deltaNC-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mi...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Mucolipin-1


(Homo sapiens)
BDBM50569843
PNG
(CHEMBL4856175)
Show SMILES COc1ccccc1N1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1 |r|
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n/an/a 3.10E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML1deltaNC-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mi...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Mucolipin-1


(Homo sapiens)
BDBM50569850
PNG
(CHEMBL4855846)
Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1 |r|
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n/an/a 4.40E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML1deltaNC-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mi...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-1


(Homo sapiens)
BDBM50569853
PNG
(CHEMBL4855589)
Show SMILES COc1ccccc1C1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1 |r|
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n/an/a 4.80E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML1deltaNC-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mi...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-2


(Homo sapiens)
BDBM50569855
PNG
(CHEMBL4851134)
Show SMILES O=S(=O)(N[C@H]1CCCC[C@@H]1N1CCc2ccccc2C1)c1ccccc1 |r|
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n/an/a 5.50E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML2-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mins by F...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-1


(Homo sapiens)
BDBM50569846
PNG
(CHEMBL4857820)
Show SMILES COc1ccccc1N1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccc(C)cc1 |r|
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n/an/a 5.60E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML1deltaNC-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mi...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-1


(Homo sapiens)
BDBM50569851
PNG
(CHEMBL4870275)
Show SMILES Cc1ccc(CN2CCN(CC2)[C@H]2CCCC[C@@H]2NS(=O)(=O)c2ccccc2)cc1 |r|
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TBA

Assay Description
Inhibition of human TRPML1deltaNC-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mi...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-1


(Homo sapiens)
BDBM50569845
PNG
(CHEMBL4851704)
Show SMILES COc1ccccc1N1CCN(CC1)[C@@H]1CCCC[C@H]1NS(=O)(=O)c1ccccc1 |r|
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n/an/a 5.90E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML1deltaNC-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mi...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-1


(Homo sapiens)
BDBM50569854
PNG
(CHEMBL4874310)
Show SMILES O=S(=O)(N[C@H]1CCCC[C@@H]1N1CCC(CC1)c1ccccc1)c1ccccc1 |r|
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n/an/a 8.90E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML1deltaNC-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mi...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-1


(Homo sapiens)
BDBM50569855
PNG
(CHEMBL4851134)
Show SMILES O=S(=O)(N[C@H]1CCCC[C@@H]1N1CCc2ccccc2C1)c1ccccc1 |r|
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n/an/a 9.50E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML1deltaNC-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mi...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-1


(Homo sapiens)
BDBM50569849
PNG
(CHEMBL4849322)
Show SMILES O=S(=O)(N[C@H]1CCCC[C@@H]1N1CCN(CC1)c1ccccc1)c1ccccc1 |r|
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n/an/a 1.49E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML1deltaNC-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mi...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-1


(Homo sapiens)
BDBM50569858
PNG
(CHEMBL4875978)
Show SMILES COc1ccc2N(C(C)C(CCN3CCOCC3)c2c1)C(=O)c1cccc(Cl)c1Cl
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n/an/a 1.50E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML1deltaNC-YFP expressed in HEK293 cells stimulated with ML-SA1 for 200 secs followed by incubation for 200 secs with compound...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-3


(Homo sapiens (Human))
BDBM50569847
PNG
(CHEMBL4847300)
Show SMILES COc1ccccc1N1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1cccs1 |r|
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n/an/a 1.59E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML3-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mins by F...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-3


(Homo sapiens (Human))
BDBM50569843
PNG
(CHEMBL4856175)
Show SMILES COc1ccccc1N1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1 |r|
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n/an/a 1.70E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML3-YFP expressed in HEK293 cells stimulated with ML-SA1 for 200 secs followed by incubation for 200 secs with compound and me...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-1


(Homo sapiens)
BDBM50569844
PNG
(CHEMBL4877013)
Show SMILES COc1ccccc1N1CCN(CC1)[C@@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1 |r|
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n/an/a 1.85E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML1deltaNC-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mi...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-3


(Homo sapiens (Human))
BDBM50569856
PNG
(CHEMBL4875551)
Show SMILES COc1ccccc1N1CCN(CC1)c1ccccc1NS(=O)(=O)c1ccccc1
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n/an/a 2.17E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML3-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mins by F...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-2


(Homo sapiens)
BDBM50569848
PNG
(CHEMBL4858349)
Show SMILES COc1ccccc1N1CCN(CC1)[C@H]1CCCC[C@@H]1NC(=O)c1ccccc1 |r|
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n/an/a 2.68E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML2-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mins by F...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-3


(Homo sapiens (Human))
BDBM50569843
PNG
(CHEMBL4856175)
Show SMILES COc1ccccc1N1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1 |r|
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n/an/a 2.85E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML3-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mins by F...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-3


(Homo sapiens (Human))
BDBM50569843
PNG
(CHEMBL4856175)
Show SMILES COc1ccccc1N1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1 |r|
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n/an/a 2.85E+4n/an/an/an/an/an/a


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Assay Description
Inhibition of human TRPML3-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mins by F...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-2


(Homo sapiens)
BDBM50569852
PNG
(CHEMBL4856325)
Show SMILES CN1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1 |r|
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n/an/a 4.02E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML2-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mins by F...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-1


(Homo sapiens)
BDBM50569852
PNG
(CHEMBL4856325)
Show SMILES CN1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1 |r|
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n/an/a 5.33E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML1deltaNC-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mi...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-3


(Homo sapiens (Human))
BDBM50569853
PNG
(CHEMBL4855589)
Show SMILES COc1ccccc1C1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1 |r|
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n/an/a 5.62E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML3-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mins by F...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-1


(Homo sapiens)
BDBM50569848
PNG
(CHEMBL4858349)
Show SMILES COc1ccccc1N1CCN(CC1)[C@H]1CCCC[C@@H]1NC(=O)c1ccccc1 |r|
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n/an/a 6.51E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML1deltaNC-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mi...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-3


(Homo sapiens (Human))
BDBM50569848
PNG
(CHEMBL4858349)
Show SMILES COc1ccccc1N1CCN(CC1)[C@H]1CCCC[C@@H]1NC(=O)c1ccccc1 |r|
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n/an/a>1.00E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML3-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mins by F...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-3


(Homo sapiens (Human))
BDBM50569852
PNG
(CHEMBL4856325)
Show SMILES CN1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1 |r|
PDB

KEGG

UniProtKB/SwissProt

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n/an/a>1.00E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML3-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mins by F...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-2


(Homo sapiens)
BDBM50569845
PNG
(CHEMBL4851704)
Show SMILES COc1ccccc1N1CCN(CC1)[C@@H]1CCCC[C@H]1NS(=O)(=O)c1ccccc1 |r|
PDB

KEGG

UniProtKB/SwissProt

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n/an/an/an/a 2.70E+3n/an/an/an/a


TBA

Assay Description
Activation of human TRPML2-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysis


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-2


(Homo sapiens)
BDBM50569846
PNG
(CHEMBL4857820)
Show SMILES COc1ccccc1N1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccc(C)cc1 |r|
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
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n/an/an/an/a 4.00E+3n/an/an/an/a


TBA

Assay Description
Activation of human TRPML2-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysis


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-2


(Homo sapiens)
BDBM50569847
PNG
(CHEMBL4847300)
Show SMILES COc1ccccc1N1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1cccs1 |r|
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
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UniChem
Article
PubMed
n/an/an/an/a 6.30E+3n/an/an/an/a


TBA

Assay Description
Activation of human TRPML2-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysis


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-2


(Homo sapiens)
BDBM50569849
PNG
(CHEMBL4849322)
Show SMILES O=S(=O)(N[C@H]1CCCC[C@@H]1N1CCN(CC1)c1ccccc1)c1ccccc1 |r|
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
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Article
PubMed
n/an/an/an/a 3.60E+3n/an/an/an/a


TBA

Assay Description
Activation of human TRPML2-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysis


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-2


(Homo sapiens)
BDBM50569850
PNG
(CHEMBL4855846)
Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1 |r|
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
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Article
PubMed
n/an/an/an/a 9.10E+3n/an/an/an/a


TBA

Assay Description
Activation of human TRPML2-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysis


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-2


(Homo sapiens)
BDBM50569851
PNG
(CHEMBL4870275)
Show SMILES Cc1ccc(CN2CCN(CC2)[C@H]2CCCC[C@@H]2NS(=O)(=O)c2ccccc2)cc1 |r|
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
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UniChem
Article
PubMed
n/an/an/an/a 4.40E+3n/an/an/an/a


TBA

Assay Description
Activation of human TRPML2-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysis


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-2


(Homo sapiens)
BDBM50569857
PNG
(CHEMBL4856363)
Show SMILES O=S(=O)(N[C@H]1CCCC[C@@H]1N1CCN(CCc2ccccc2)CC1)c1ccccc1 |r|
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 3.60E+3n/an/an/an/a


TBA

Assay Description
Activation of human TRPML2-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysis


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-2


(Homo sapiens)
BDBM50569853
PNG
(CHEMBL4855589)
Show SMILES COc1ccccc1C1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1 |r|
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
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Article
PubMed
n/an/an/an/a 3.90E+3n/an/an/an/a


TBA

Assay Description
Activation of human TRPML2-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysis


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-2


(Homo sapiens)
BDBM50569854
PNG
(CHEMBL4874310)
Show SMILES O=S(=O)(N[C@H]1CCCC[C@@H]1N1CCC(CC1)c1ccccc1)c1ccccc1 |r|
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 3.70E+3n/an/an/an/a


TBA

Assay Description
Activation of human TRPML2-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysis


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-2


(Homo sapiens)
BDBM50569856
PNG
(CHEMBL4875551)
Show SMILES COc1ccccc1N1CCN(CC1)c1ccccc1NS(=O)(=O)c1ccccc1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.10E+3n/an/an/an/a


TBA

Assay Description
Activation of human TRPML2-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysis


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-3


(Homo sapiens (Human))
BDBM50569844
PNG
(CHEMBL4877013)
Show SMILES COc1ccccc1N1CCN(CC1)[C@@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1 |r|
PDB

KEGG

UniProtKB/SwissProt

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PC cid
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UniChem
Article
PubMed
n/an/an/an/a 2.90E+4n/an/an/an/a


TBA

Assay Description
Activation of human TRPML3-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysis


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-3


(Homo sapiens (Human))
BDBM50569845
PNG
(CHEMBL4851704)
Show SMILES COc1ccccc1N1CCN(CC1)[C@@H]1CCCC[C@H]1NS(=O)(=O)c1ccccc1 |r|
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
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MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.08E+4n/an/an/an/a


TBA

Assay Description
Activation of human TRPML3-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysis


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-3


(Homo sapiens (Human))
BDBM50569846
PNG
(CHEMBL4857820)
Show SMILES COc1ccccc1N1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccc(C)cc1 |r|
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 8.50E+3n/an/an/an/a


TBA

Assay Description
Activation of human TRPML3-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysis


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-3


(Homo sapiens (Human))
BDBM50569849
PNG
(CHEMBL4849322)
Show SMILES O=S(=O)(N[C@H]1CCCC[C@@H]1N1CCN(CC1)c1ccccc1)c1ccccc1 |r|
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 9.50E+3n/an/an/an/a


TBA

Assay Description
Activation of human TRPML3-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysis


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-3


(Homo sapiens (Human))
BDBM50569850
PNG
(CHEMBL4855846)
Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1 |r|
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
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Article
PubMed
n/an/an/an/a 1.46E+4n/an/an/an/a


TBA

Assay Description
Activation of human TRPML3-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysis


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-3


(Homo sapiens (Human))
BDBM50569851
PNG
(CHEMBL4870275)
Show SMILES Cc1ccc(CN2CCN(CC2)[C@H]2CCCC[C@@H]2NS(=O)(=O)c2ccccc2)cc1 |r|
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
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Article
PubMed
n/an/an/an/a 5.80E+3n/an/an/an/a


TBA

Assay Description
Activation of human TRPML3-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysis


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-3


(Homo sapiens (Human))
BDBM50569857
PNG
(CHEMBL4856363)
Show SMILES O=S(=O)(N[C@H]1CCCC[C@@H]1N1CCN(CCc2ccccc2)CC1)c1ccccc1 |r|
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 5.40E+3n/an/an/an/a


TBA

Assay Description
Activation of human TRPML3-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysis


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-3


(Homo sapiens (Human))
BDBM50569854
PNG
(CHEMBL4874310)
Show SMILES O=S(=O)(N[C@H]1CCCC[C@@H]1N1CCC(CC1)c1ccccc1)c1ccccc1 |r|
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 2.07E+4n/an/an/an/a


TBA

Assay Description
Activation of human TRPML3-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysis


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-3


(Homo sapiens (Human))
BDBM50569855
PNG
(CHEMBL4851134)
Show SMILES O=S(=O)(N[C@H]1CCCC[C@@H]1N1CCc2ccccc2C1)c1ccccc1 |r|
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 9.50E+3n/an/an/an/a


TBA

Assay Description
Activation of human TRPML3-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysis


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-1


(Homo sapiens)
BDBM50569857
PNG
(CHEMBL4856363)
Show SMILES O=S(=O)(N[C@H]1CCCC[C@@H]1N1CCN(CCc2ccccc2)CC1)c1ccccc1 |r|
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 9.40E+3n/an/an/an/a


TBA

Assay Description
Activation of human TRPML1deltaNC-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysis


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-2


(Homo sapiens)
BDBM50569843
PNG
(CHEMBL4856175)
Show SMILES COc1ccccc1N1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1 |r|
PDB

KEGG

UniProtKB/SwissProt

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PC cid
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PDB
UniChem
Article
PubMed
n/an/an/an/a 3.30E+3n/an/an/an/a


TBA

Assay Description
Activation of human TRPML2-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysis


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
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