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Compile Data Set for Download or QSAR

Found 29 hits Enz. Inhib. hit(s) with all data for entry = 50013825   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50570077
PNG
(CHEMBL4874971)
Show SMILES Cc1ccc(cc1)-n1cc(nn1)-c1ccc(\C=C2/C(=O)Nc3ccccc23)cc1
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n/an/a 2.64E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50570091
PNG
(CHEMBL4866291)
Show SMILES Cc1ccc(cc1)-n1cc(nn1)-c1ccc(\C=C2/C(=O)Nc3ccc(F)cc23)cc1
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n/an/a 3.69E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50570076
PNG
(CHEMBL4864168)
Show SMILES Cc1cccc(c1)-n1cc(nn1)-c1ccc(\C=C2/C(=O)Nc3ccccc23)cc1
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n/an/a 4.47E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50570089
PNG
(CHEMBL4863263)
Show SMILES Cc1ccccc1-n1cc(nn1)-c1ccc(C=C2C(=O)Nc3ccc(F)cc23)cc1
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n/an/a 7.16E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM4814
PNG
(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C
Show InChI InChI=1S/C22H27FN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12-
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n/an/a 8.32E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50570090
PNG
(CHEMBL4857454)
Show SMILES Cc1cccc(c1)-n1cc(nn1)-c1ccc(\C=C2/C(=O)Nc3ccc(F)cc23)cc1
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n/an/a 8.92E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50570074
PNG
(CHEMBL4856891)
Show SMILES O=C1Nc2ccccc2\C1=C\c1ccc(cc1)-c1cn(nn1)-c1ccccc1
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n/an/a 9.31E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50570088
PNG
(CHEMBL4847439)
Show SMILES Fc1ccc2NC(=O)C(=Cc3ccc(cc3)-c3cn(nn3)-c3ccccc3)c2c1
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n/an/a 9.97E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50570087
PNG
(CHEMBL4864073)
Show SMILES FC(F)(F)c1cc(ccc1Cl)-n1cc(nn1)-c1ccc(\C=C2/C(=O)Nc3ccccc23)cc1
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n/an/a 1.08E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50570075
PNG
(CHEMBL4873974)
Show SMILES Cc1ccccc1-n1cc(nn1)-c1ccc(\C=C2/C(=O)Nc3ccccc23)cc1
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n/an/a 1.11E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50570078
PNG
(CHEMBL4856794)
Show SMILES Fc1ccccc1-n1cc(nn1)-c1ccc(\C=C2/C(=O)Nc3ccccc23)cc1
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n/an/a 1.15E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50570095
PNG
(CHEMBL4856663)
Show SMILES Fc1ccc2NC(=O)\C(=C/c3ccc(cc3)-c3cn(nn3)-c3ccccc3Cl)c2c1
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n/an/a 1.20E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50570092
PNG
(CHEMBL4876341)
Show SMILES Fc1ccc2NC(=O)\C(=C/c3ccc(cc3)-c3cn(nn3)-c3ccccc3F)c2c1
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n/an/a 1.40E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50570083
PNG
(CHEMBL4872149)
Show SMILES Clc1ccc(cc1)-n1cc(nn1)-c1ccc(\C=C2/C(=O)Nc3ccccc23)cc1
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n/an/a 1.63E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50570101
PNG
(CHEMBL4846157)
Show SMILES Fc1ccc2NC(=O)\C(=C/c3ccc(cc3)-c3cn(nn3)-c3ccc(Cl)c(c3)C(F)(F)F)c2c1
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n/an/a 1.69E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50570084
PNG
(CHEMBL4878880)
Show SMILES O=C1Nc2ccccc2\C1=C\c1ccc(cc1)-c1cn(nn1)-c1ccccc1C#N
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n/an/a 1.69E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50570097
PNG
(CHEMBL4871475)
Show SMILES Fc1ccc2NC(=O)C(=Cc3ccc(cc3)-c3cn(nn3)-c3ccc(Cl)cc3)c2c1
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n/an/a 1.70E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50570093
PNG
(CHEMBL4877074)
Show SMILES Fc1ccc2NC(=O)\C(=C/c3ccc(cc3)-c3cn(nn3)-c3cccc(F)c3)c2c1
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n/an/a 1.71E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50570086
PNG
(CHEMBL4872013)
Show SMILES O=C1Nc2ccccc2C1=Cc1ccc(cc1)-c1cn(nn1)-c1ccc(cc1)C#N
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n/an/a 1.79E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50570096
PNG
(CHEMBL4854778)
Show SMILES Fc1ccc2NC(=O)\C(=C/c3ccc(cc3)-c3cn(nn3)-c3cccc(Cl)c3)c2c1
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n/an/a 1.86E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50570098
PNG
(CHEMBL4847210)
Show SMILES Fc1ccc2NC(=O)C(=Cc3ccc(cc3)-c3cn(nn3)-c3ccccc3C#N)c2c1
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n/an/a 1.87E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50570100
PNG
(CHEMBL4866727)
Show SMILES Fc1ccc2NC(=O)C(=Cc3ccc(cc3)-c3cn(nn3)-c3ccc(cc3)C#N)c2c1
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n/an/a 1.90E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50570094
PNG
(CHEMBL4853198)
Show SMILES Fc1ccc(cc1)-n1cc(nn1)-c1ccc(\C=C2/C(=O)Nc3ccc(F)cc23)cc1
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n/an/a 1.93E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50570099
PNG
(CHEMBL4866203)
Show SMILES Fc1ccc2NC(=O)\C(=C/c3ccc(cc3)-c3cn(nn3)-c3cccc(c3)C#N)c2c1
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n/an/a 1.93E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50570080
PNG
(CHEMBL4877343)
Show SMILES Fc1ccc(cc1)-n1cc(nn1)-c1ccc(\C=C2/C(=O)Nc3ccccc23)cc1
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n/an/a 1.99E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50570085
PNG
(CHEMBL4878024)
Show SMILES O=C1Nc2ccccc2\C1=C\c1ccc(cc1)-c1cn(nn1)-c1cccc(c1)C#N
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n/an/a>2.00E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50570082
PNG
(CHEMBL4848005)
Show SMILES Clc1cccc(c1)-n1cc(nn1)-c1ccc(\C=C2/C(=O)Nc3ccccc23)cc1
PDB
MMDB

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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50570081
PNG
(CHEMBL4869269)
Show SMILES Clc1ccccc1-n1cc(nn1)-c1ccc(\C=C2/C(=O)Nc3ccccc23)cc1
PDB
MMDB

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UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50570079
PNG
(CHEMBL4850246)
Show SMILES Fc1cccc(c1)-n1cc(nn1)-c1ccc(\C=C2/C(=O)Nc3ccccc23)cc1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human His-tagged VEGFR2 expressed in Baculovirus expression system using ADP-Glo as substrate measured after 30 mins in pre...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.113083
BindingDB Entry DOI: 10.7270/Q2TX3K4B
More data for this
Ligand-Target Pair