Found 75 hits Enz. Inhib. hit(s) with all data for entry = 50013982 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571425
(CHEMBL4871310)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(c3)-c3cnn(C)c3)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50571440
(CHEMBL4873571)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human MET (974 to end residues) using KKKGQEEEYVFIE as substrate incubated for 40 mins in presence of [gamma-33ATP by scint... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571440
(CHEMBL4873571)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor TYRO3
(Homo sapiens (Human)) | BDBM50571440
(CHEMBL4873571)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human RSE (451 to end residues) using KVEKIGEGTYGVVYK as substrate incubated for 40 mins in presence of [gamma33P]ATP by sc... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571442
(CHEMBL4861161)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(NC(=O)N4CCCC4)c3)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571424
(CHEMBL4858048)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(c3)-c3cnn(C)c3)cc2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571431
(CHEMBL4863290)Show SMILES CC(C)n1cc(C(=O)Nc2cc(F)c(Oc3ccnc(c3)-c3cnn(C)c3)cc2F)c(=O)n(-c2ccc(F)cc2)c1=O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571437
(CHEMBL4869458)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(c3)-c3cn[nH]c3)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571432
(CHEMBL4864676)Show SMILES CC(C)n1cc(C(=O)Nc2cc(F)c(Oc3ccnc(c3)-c3cnn(C)c3)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM144315
(Gilteritinib | US11512074, Example T-9 | US8969336...)Show SMILES CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)nc1NC1CCOCC1 Show InChI InChI=1S/C29H44N8O3/c1-4-23-28(31-20-9-17-40-18-10-20)34-29(26(33-23)27(30)38)32-21-5-6-24(25(19-21)39-3)37-11-7-22(8-12-37)36-15-13-35(2)14-16-36/h5-6,19-20,22H,4,7-18H2,1-3H3,(H2,30,38)(H2,31,32,34) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571423
(CHEMBL4857746)Show SMILES Nc1nc(Nc2ccc3CC[C@H](CCc3c2)N2CCCC2)nn1-c1cc2CCCc3ccccc3-c2nn1 |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571430
(CHEMBL4846125)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(c3)-c3cnn(C)c3)c(F)c2F)c(=O)n(-c2ccc(F)cc2)c1=O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571426
(CHEMBL4867669)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(c3)-c3cnn(C)c3)cc2F)c(=O)n(-c2ccc(F)cc2)c1=O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571439
(CHEMBL4855681)Show SMILES CCC(=O)Nc1cc(Oc2ccc(NC(=O)c3cn(C(C)C)c(=O)n(-c4ccc(F)cc4)c3=O)cc2F)ccn1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571438
(CHEMBL4856526)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(NC(C)=O)c3)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571441
(CHEMBL4856234)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CCC4)c3)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571443
(CHEMBL4875798)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(NC(=O)N4CCOCC4)c3)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 8.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571415
(CHEMBL4875876)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccncc3-c3cnn(C)c3)cc2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 8.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571414
(CHEMBL4851321)Show SMILES CCn1cc(C(=O)Nc2ccc(Oc3ccncc3-c3cnn(C)c3)cc2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 8.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase Mer
(Homo sapiens (Human)) | BDBM50571440
(CHEMBL4873571)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human MER (557 to 882 residues) using GGMEDIYFEFMGG as substrate incubated for 40 mins in presence of [gamma-33ATP by scint... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571434
(CHEMBL4846678)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(c3)-c3cnn(c3)C3CC3)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571412
(CHEMBL4856142)Show SMILES Cn1cc(cn1)-c1cnccc1Oc1ccc(NC(=O)c2c[nH]c(=O)n(-c3ccc(F)cc3)c2=O)cc1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571435
(CHEMBL4848473)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(c3)-c3cnn(CC(C)(C)O)c3)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571420
(CHEMBL4853182)Show SMILES Cn1cc(cn1)-c1cnccc1Oc1ccc(NC(=O)c2cc3C(=O)CCCc3n(-c3ccc(F)cc3)c2=O)cc1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571410
(CHEMBL4861226)Show SMILES Cc1ncc(C(=O)Nc2ccc(Oc3ccncc3-c3cnn(C)c3)cc2)c(=O)n1-c1ccc(F)cc1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571427
(CHEMBL4864426)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(c3)-c3cnn(C)c3)c(Cl)c2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571436
(CHEMBL4872759)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(c3)-c3cnn(CCN4CCN(C)CC4)c3)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571433
(CHEMBL4863687)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(c3)-c3cn(C)nc3C)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571428
(CHEMBL4849593)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(c3)-c3cnn(C)c3)c(C)c2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571416
(CHEMBL4858649)Show SMILES Cn1cc(cn1)-c1cnccc1Oc1ccc(NC(=O)c2cn(CC3CCOCC3)c(=O)n(-c3ccc(F)cc3)c2=O)cc1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase 20
(Homo sapiens (Human)) | BDBM50571440
(CHEMBL4873571)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB
NCI pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant full-length human ZAK using MBP as substrate incubated for 40 mins in presence of [gamma33P]ATP by scintillation counting b... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Ephrin type-A receptor 2
(Homo sapiens (Human)) | BDBM50571440
(CHEMBL4873571)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human EphA2 (596 to 900 residues) using poly(Glu, Tyr) 4:1 as substrate incubated for 40 mins in presence of [gamma-33ATP] ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase SYK
(Homo sapiens (Human)) | BDBM50571440
(CHEMBL4873571)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human full length SYK using poly(Glu, Tyr) 4:1 as substrate incubated for 40 mins in presence of [gamma33P]ATP by scintilla... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571421
(CHEMBL4866212)Show SMILES Cn1cc(cn1)-c1cnccc1Oc1ccc(NC(=O)C2Cc3ccncc3N(C2=O)c2ccc(F)cc2)cc1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571417
(CHEMBL4856528)Show SMILES CC(C)n1nc(C(=O)Nc2ccc(Oc3ccncc3-c3cnn(C)c3)cc2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 179 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571413
(CHEMBL4856829)Show SMILES Cn1cc(cn1)-c1cnccc1Oc1ccc(NC(=O)c2cn(C)c(=O)n(-c3ccc(F)cc3)c2=O)cc1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 185 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571408
(CHEMBL4845715)Show SMILES Cc1c(C(=O)Nc2ccc(Oc3ccncc3-c3cnn(C)c3)cc2)c(=O)n(-c2ccccc2)n1C | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 254 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571411
(CHEMBL4879206)Show SMILES Cc1nc(C)n(-c2ccc(F)cc2)c(=O)c1C(=O)Nc1ccc(Oc2ccncc2-c2cnn(C)c2)cc1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 396 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571409
(CHEMBL4848709)Show SMILES CCOc1cn(nc1C(=O)Nc1ccc(Oc2ccncc2-c2cnn(C)c2)cc1)-c1ccc(F)cc1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571418
(CHEMBL4848206)Show SMILES Cn1cc(cn1)-c1cnccc1Oc1ccc(NC(=O)C2=C(c3ccccc3C2=O)c2ccccc2)cc1 |t:22| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571419
(CHEMBL4864950)Show SMILES Cn1cc(cn1)-c1cnccc1Oc1ccc(NC(=O)c2c3CCCC(=O)c3cn(-c3ccccc3)c2=O)cc1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571422
(CHEMBL4862247)Show SMILES CCc1ccc2n(C)c(C)c(C(=O)Nc3ccc(Oc4ccncc4-c4cnn(C)c4)cc3)c(=O)c2c1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50571429
(CHEMBL4863885)Show SMILES COc1cc(NC(=O)c2cn(C(C)C)c(=O)n(-c3ccc(F)cc3)c2=O)ccc1Oc1ccnc(c1)-c1cnn(C)c1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of AXL (unknown origin) using poly [Glu, Tyr] 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase BTK
(Homo sapiens (Human)) | BDBM50571440
(CHEMBL4873571)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of full length recombinant human BTK using KVEKIGEGTYGVVYK as substrate incubated for 40 mins in presence of [gamma-33P]-ATP by scintillat... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50571440
(CHEMBL4873571)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human ALK (1058 to end residues) using KKKSPGEYVNIEFG as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 1
(Homo sapiens (Human)) | BDBM50571440
(CHEMBL4873571)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human FGFR1 (456 to 765 residues) using KKKSPGEYVNIEF as substrate incubated for 40 mins in presence of [gamma-33ATP] by ra... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50571440
(CHEMBL4873571)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human FLT1 (783 to end residues) using KKKSPGEYVNIEFG as substrate incubated for 40 mins in presence of [gamma-33ATP] by sc... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50571440
(CHEMBL4873571)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human KDR (790 to end residues) using myelin basic protein as substrate incubated for 40 mins by [gamma-33P]-ATP scintillat... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human)) | BDBM50571440
(CHEMBL4873571)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human PDGFRalpha (550 to end residues) using poly(Glu, Tyr) 4:1 as substrate measured after 40 mins in presence of [gamma33P]ATP by sci... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Homo sapiens (Human)) | BDBM50571440
(CHEMBL4873571)Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human PDGFRbeta (557 to end residues) using poly(Glu, Tyr) 4:1 as substrate measured after 40 mins in presence of [gamma33P]ATP by scin... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02093 BindingDB Entry DOI: 10.7270/Q2PR80SR |
More data for this Ligand-Target Pair | |