Compile Data Set for Download or QSAR

Found 48 hits Enz. Inhib. hit(s) with all data for entry = 50014005   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM418817 (N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]...) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3nccnc3N(C)S(C)(=O)=O)n2)C(F)(F)F)cc1 Show InChI InChI=1S/C20H21F3N8O3S/c1-24-18(32)12-4-6-13(7-5-12)29-19-28-10-14(20(21,22)23)16(30-19)27-11-15-17(26-9-8-25-15)31(2)35(3,33)34/h4-10H,11H2,1-3H3,(H,24,32)(H2,27,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50571721 (CHEMBL4874046) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(Nc3ccccc3OC)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50571706 (CHEMBL4850588) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3ccccc3Cl)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50571710 (CHEMBL4872224) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3cccc(Br)c3)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50571708 (CHEMBL4873348) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3cccc(F)c3)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50571711 (CHEMBL4860092) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3ccc(F)cc3)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50571709 (CHEMBL4853818) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3cccc(Cl)c3)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50571714 (CHEMBL4874518) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3ccccc3OC)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50571705 (CHEMBL4865567) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3ccccc3F)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50571707 (CHEMBL4850002) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3ccccc3Br)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50571718 (CHEMBL4849851) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(Nc3ccccc3[N+]([O-])=O)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50571721 (CHEMBL4874046) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(Nc3ccccc3OC)n2)C(F)(F)F)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of JAK2 (unknown origin) measured after 40 mins by HTRF				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50571721 (CHEMBL4874046) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(Nc3ccccc3OC)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TRKA (unknown origin) measured after 40 mins by HTRF				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50571727 (CHEMBL4869055) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(Nc3ccc(NS(C)(=O)=O)cc3)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50571721 (CHEMBL4874046) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(Nc3ccccc3OC)n2)C(F)(F)F)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of JAK3 (unknown origin) measured after 40 mins by HTRF				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50571726 (CHEMBL4877387) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(Nc3ccc(NC(C)=O)cc3)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50571721 (CHEMBL4874046) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(Nc3ccccc3OC)n2)C(F)(F)F)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TYK2 (unknown origin) measured after 40 mins by HTRF				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50571722 (CHEMBL4858762) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(Nc3cccc(OC)c3)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM50571721 (CHEMBL4874046) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(Nc3ccccc3OC)n2)C(F)(F)F)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Pyk2 (unknown origin) measured after 40 mins by HTRF				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50571719 (CHEMBL4863844) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(Nc3ccc(N)cc3)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM418817 (N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]...) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3nccnc3N(C)S(C)(=O)=O)n2)C(F)(F)F)cc1 Show InChI InChI=1S/C20H21F3N8O3S/c1-24-18(32)12-4-6-13(7-5-12)29-19-28-10-14(20(21,22)23)16(30-19)27-11-15-17(26-9-8-25-15)31(2)35(3,33)34/h4-10H,11H2,1-3H3,(H,24,32)(H2,27,28,29,30)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TRKA (unknown origin) measured after 40 mins by HTRF				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM418817 (N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]...) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3nccnc3N(C)S(C)(=O)=O)n2)C(F)(F)F)cc1 Show InChI InChI=1S/C20H21F3N8O3S/c1-24-18(32)12-4-6-13(7-5-12)29-19-28-10-14(20(21,22)23)16(30-19)27-11-15-17(26-9-8-25-15)31(2)35(3,33)34/h4-10H,11H2,1-3H3,(H,24,32)(H2,27,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of JAK2 (unknown origin) measured after 40 mins by HTRF				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50571715 (CHEMBL4849923) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3ccc(OC)cc3)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
NT-3 growth factor receptor (Homo sapiens (Human))	BDBM50571721 (CHEMBL4874046) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(Nc3ccccc3OC)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TRKC (unknown origin) measured after 40 mins by HTRF				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50571720 (CHEMBL4864858) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(Nc3cccc(N)c3)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50571716 (CHEMBL4847034) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(Nc3ccc(F)cc3)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50571706 (CHEMBL4850588) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3ccccc3Cl)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TRKA (unknown origin) measured after 40 mins by HTRF				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50571717 (CHEMBL4852217) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(Nc3ccccc3Cl)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50571725 (CHEMBL4869158) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(Nc3ccc(OC)c(Cl)c3)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50571712 (CHEMBL4879100) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3ccc(Cl)cc3)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50571706 (CHEMBL4850588) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3ccccc3Cl)n2)C(F)(F)F)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of JAK2 (unknown origin) measured after 40 mins by HTRF				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
BDNF/NT-3 growth factors receptor (Homo sapiens (Human))	BDBM50571721 (CHEMBL4874046) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(Nc3ccccc3OC)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TRKB (unknown origin) measured after 40 mins by HTRF				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50571724 (CHEMBL4848228) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(Nc3ccc(OC)c(F)c3)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50571706 (CHEMBL4850588) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3ccccc3Cl)n2)C(F)(F)F)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TYK2 (unknown origin) measured after 40 mins by HTRF				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50571713 (CHEMBL4864144) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3ccc(Br)cc3)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50571706 (CHEMBL4850588) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3ccccc3Cl)n2)C(F)(F)F)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of JAK3 (unknown origin) measured after 40 mins by HTRF				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
BDNF/NT-3 growth factors receptor (Homo sapiens (Human))	BDBM418817 (N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]...) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3nccnc3N(C)S(C)(=O)=O)n2)C(F)(F)F)cc1 Show InChI InChI=1S/C20H21F3N8O3S/c1-24-18(32)12-4-6-13(7-5-12)29-19-28-10-14(20(21,22)23)16(30-19)27-11-15-17(26-9-8-25-15)31(2)35(3,33)34/h4-10H,11H2,1-3H3,(H,24,32)(H2,27,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TRKB (unknown origin) measured after 40 mins by HTRF				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50571723 (CHEMBL4867150) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(Nc3ccc(OC)cc3)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
NT-3 growth factor receptor (Homo sapiens (Human))	BDBM418817 (N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]...) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3nccnc3N(C)S(C)(=O)=O)n2)C(F)(F)F)cc1 Show InChI InChI=1S/C20H21F3N8O3S/c1-24-18(32)12-4-6-13(7-5-12)29-19-28-10-14(20(21,22)23)16(30-19)27-11-15-17(26-9-8-25-15)31(2)35(3,33)34/h4-10H,11H2,1-3H3,(H,24,32)(H2,27,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TRKC (unknown origin) measured after 40 mins by HTRF				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM418817 (N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]...) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3nccnc3N(C)S(C)(=O)=O)n2)C(F)(F)F)cc1 Show InChI InChI=1S/C20H21F3N8O3S/c1-24-18(32)12-4-6-13(7-5-12)29-19-28-10-14(20(21,22)23)16(30-19)27-11-15-17(26-9-8-25-15)31(2)35(3,33)34/h4-10H,11H2,1-3H3,(H,24,32)(H2,27,28,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Pyk2 (unknown origin) measured after 40 mins by HTRF				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
NT-3 growth factor receptor (Homo sapiens (Human))	BDBM50571706 (CHEMBL4850588) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3ccccc3Cl)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TRKC (unknown origin) measured after 40 mins by HTRF				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
BDNF/NT-3 growth factors receptor (Homo sapiens (Human))	BDBM50571706 (CHEMBL4850588) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3ccccc3Cl)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	103	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TRKB (unknown origin) measured after 40 mins by HTRF				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM418817 (N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]...) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3nccnc3N(C)S(C)(=O)=O)n2)C(F)(F)F)cc1 Show InChI InChI=1S/C20H21F3N8O3S/c1-24-18(32)12-4-6-13(7-5-12)29-19-28-10-14(20(21,22)23)16(30-19)27-11-15-17(26-9-8-25-15)31(2)35(3,33)34/h4-10H,11H2,1-3H3,(H,24,32)(H2,27,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	115	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of JAK3 (unknown origin) measured after 40 mins by HTRF				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM50571706 (CHEMBL4850588) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3ccccc3Cl)n2)C(F)(F)F)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	116	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Pyk2 (unknown origin) measured after 40 mins by HTRF				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM418817 (N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]...) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3nccnc3N(C)S(C)(=O)=O)n2)C(F)(F)F)cc1 Show InChI InChI=1S/C20H21F3N8O3S/c1-24-18(32)12-4-6-13(7-5-12)29-19-28-10-14(20(21,22)23)16(30-19)27-11-15-17(26-9-8-25-15)31(2)35(3,33)34/h4-10H,11H2,1-3H3,(H,24,32)(H2,27,28,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	129	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TYK2 (unknown origin) measured after 40 mins by HTRF				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50571706 (CHEMBL4850588) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3ccccc3Cl)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	147	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of VEGFR-2 (unknown origin) incubated for 40 mins by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM418817 (N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]...) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3nccnc3N(C)S(C)(=O)=O)n2)C(F)(F)F)cc1 Show InChI InChI=1S/C20H21F3N8O3S/c1-24-18(32)12-4-6-13(7-5-12)29-19-28-10-14(20(21,22)23)16(30-19)27-11-15-17(26-9-8-25-15)31(2)35(3,33)34/h4-10H,11H2,1-3H3,(H,24,32)(H2,27,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	273	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of VEGFR-2 (unknown origin) incubated for 40 mins by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50571721 (CHEMBL4874046) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(Nc3ccccc3OC)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	292	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of VEGFR-2 (unknown origin) incubated for 40 mins by HTRF assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113573 BindingDB Entry DOI: 10.7270/Q2125XFH
					More data for this Ligand-Target Pair