Found 54 hits Enz. Inhib. hit(s) with all data for entry = 50014295 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140506
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cy...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(CCC2CCCC2)CC1)C(=O)\C=C\c1cccc(c1)C#N Show InChI InChI=1S/C32H38N4O2/c1-24(37)35-20-14-28-10-11-30(22-31(28)35)36(32(38)12-9-26-7-4-8-27(21-26)23-33)29-15-18-34(19-16-29)17-13-25-5-2-3-6-25/h4,7-12,21-22,25,29H,2-3,5-6,13-20H2,1H3/b12-9+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards human NPY Y2 receptor was determined using [35S]-GTP-gammaS, radioligand |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140478
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-[1-(2...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(CCC2CCCC2)CC1)C(=O)\C=C\c1cccc(c1)[N+]([O-])=O Show InChI InChI=1S/C31H38N4O4/c1-23(36)33-20-14-26-10-11-28(22-30(26)33)34(31(37)12-9-25-7-4-8-29(21-25)35(38)39)27-15-18-32(19-16-27)17-13-24-5-2-3-6-24/h4,7-12,21-22,24,27H,2-3,5-6,13-20H2,1H3/b12-9+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140494
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-[1-(2...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(CCC2CCCCC2)CC1)C(=O)\C=C\c1cccc(c1)[N+]([O-])=O Show InChI InChI=1S/C32H40N4O4/c1-24(37)34-21-15-27-11-12-29(23-31(27)34)35(32(38)13-10-26-8-5-9-30(22-26)36(39)40)28-16-19-33(20-17-28)18-14-25-6-3-2-4-7-25/h5,8-13,22-23,25,28H,2-4,6-7,14-21H2,1H3/b13-10+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140464
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-[1-(2...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(CCC2CCCCC2)CC1)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C32H41N3O2/c1-25(36)34-23-17-28-13-14-30(24-31(28)34)35(32(37)15-12-26-8-4-2-5-9-26)29-18-21-33(22-19-29)20-16-27-10-6-3-7-11-27/h2,4-5,8-9,12-15,24,27,29H,3,6-7,10-11,16-23H2,1H3/b15-12+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140475
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-[1-(2...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(CCC2CCCC2)CC1)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C31H39N3O2/c1-24(35)33-22-16-27-12-13-29(23-30(27)33)34(31(36)14-11-25-7-3-2-4-8-25)28-17-20-32(21-18-28)19-15-26-9-5-6-10-26/h2-4,7-8,11-14,23,26,28H,5-6,9-10,15-22H2,1H3/b14-11+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140487
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-be...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1cccc(c1)C#N Show InChI InChI=1S/C32H32N4O2/c1-24(37)35-19-14-28-11-12-30(21-31(28)35)36(32(38)13-10-25-8-5-9-27(20-25)22-33)29-15-17-34(18-16-29)23-26-6-3-2-4-7-26/h2-13,20-21,29H,14-19,23H2,1H3/b13-10+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140457
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(4-ch...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(CCC2CCCCC2)CC1)C(=O)\C=C\c1ccc(Cl)cc1 Show InChI InChI=1S/C32H40ClN3O2/c1-24(37)35-22-16-27-10-13-30(23-31(27)35)36(32(38)14-9-26-7-11-28(33)12-8-26)29-17-20-34(21-18-29)19-15-25-5-3-2-4-6-25/h7-14,23,25,29H,2-6,15-22H2,1H3/b14-9+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140509
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-cy...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(CC2CCCCC2)CC1)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C31H39N3O2/c1-24(35)33-21-16-27-13-14-29(22-30(27)33)34(31(36)15-12-25-8-4-2-5-9-25)28-17-19-32(20-18-28)23-26-10-6-3-7-11-26/h2,4-5,8-9,12-15,22,26,28H,3,6-7,10-11,16-21,23H2,1H3/b15-12+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140465
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(4-ch...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(CCC2CCCC2)CC1)C(=O)\C=C\c1ccc(Cl)cc1 Show InChI InChI=1S/C31H38ClN3O2/c1-23(36)34-21-15-26-9-12-29(22-30(26)34)35(31(37)13-8-25-6-10-27(32)11-7-25)28-16-19-33(20-17-28)18-14-24-4-2-3-5-24/h6-13,22,24,28H,2-5,14-21H2,1H3/b13-8+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140505
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-be...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1cccc(C)c1 Show InChI InChI=1S/C32H35N3O2/c1-24-7-6-10-26(21-24)11-14-32(37)35(30-13-12-28-15-20-34(25(2)36)31(28)22-30)29-16-18-33(19-17-29)23-27-8-4-3-5-9-27/h3-14,21-22,29H,15-20,23H2,1-2H3/b14-11+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140468
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-be...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1cccc(c1)[N+]([O-])=O Show InChI InChI=1S/C31H32N4O4/c1-23(36)33-19-14-26-11-12-28(21-30(26)33)34(31(37)13-10-24-8-5-9-29(20-24)35(38)39)27-15-17-32(18-16-27)22-25-6-3-2-4-7-25/h2-13,20-21,27H,14-19,22H2,1H3/b13-10+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140486
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-pheny...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(CCCc2ccccc2)CC1)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C33H37N3O2/c1-26(37)35-24-18-29-15-16-31(25-32(29)35)36(33(38)17-14-28-11-6-3-7-12-28)30-19-22-34(23-20-30)21-8-13-27-9-4-2-5-10-27/h2-7,9-12,14-17,25,30H,8,13,18-24H2,1H3/b17-14+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140460
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-be...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1cc(F)cc(F)c1 Show InChI InChI=1S/C31H31F2N3O2/c1-22(37)35-16-11-25-8-9-29(20-30(25)35)36(31(38)10-7-24-17-26(32)19-27(33)18-24)28-12-14-34(15-13-28)21-23-5-3-2-4-6-23/h2-10,17-20,28H,11-16,21H2,1H3/b10-7+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140507
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-be...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C32H32F3N3O2/c1-23(39)37-20-15-26-10-13-29(21-30(26)37)38(28-16-18-36(19-17-28)22-25-5-3-2-4-6-25)31(40)14-9-24-7-11-27(12-8-24)32(33,34)35/h2-14,21,28H,15-20,22H2,1H3/b14-9+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140480
((2E,4E)-5-Phenyl-penta-2,4-dienoic acid (1-acetyl-...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\C=C\c1ccccc1 Show InChI InChI=1S/C33H35N3O2/c1-26(37)35-23-18-29-16-17-31(24-32(29)35)36(33(38)15-9-8-12-27-10-4-2-5-11-27)30-19-21-34(22-20-30)25-28-13-6-3-7-14-28/h2-17,24,30H,18-23,25H2,1H3/b12-8+,15-9+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140462
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-be...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1cccc(Cl)c1 Show InChI InChI=1S/C31H32ClN3O2/c1-23(36)34-19-14-26-11-12-29(21-30(26)34)35(31(37)13-10-24-8-5-9-27(32)20-24)28-15-17-33(18-16-28)22-25-6-3-2-4-7-25/h2-13,20-21,28H,14-19,22H2,1H3/b13-10+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140489
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-be...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1ccsc1 Show InChI InChI=1S/C29H31N3O2S/c1-22(33)31-17-11-25-8-9-27(19-28(25)31)32(29(34)10-7-24-14-18-35-21-24)26-12-15-30(16-13-26)20-23-5-3-2-4-6-23/h2-10,14,18-19,21,26H,11-13,15-17,20H2,1H3/b10-7+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140503
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-be...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1cccc(Br)c1 Show InChI InChI=1S/C31H32BrN3O2/c1-23(36)34-19-14-26-11-12-29(21-30(26)34)35(31(37)13-10-24-8-5-9-27(32)20-24)28-15-17-33(18-16-28)22-25-6-3-2-4-7-25/h2-13,20-21,28H,14-19,22H2,1H3/b13-10+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140500
((E)-N-(1-Benzyl-piperidin-4-yl)-N-(1-formyl-2,3-di...)Show SMILES O=CN1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C30H31N3O2/c34-23-32-20-15-26-12-13-28(21-29(26)32)33(30(35)14-11-24-7-3-1-4-8-24)27-16-18-31(19-17-27)22-25-9-5-2-6-10-25/h1-14,21,23,27H,15-20,22H2/b14-11+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140499
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-be...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1ccc(Cl)cc1 Show InChI InChI=1S/C31H32ClN3O2/c1-23(36)34-20-15-26-10-13-29(21-30(26)34)35(31(37)14-9-24-7-11-27(32)12-8-24)28-16-18-33(19-17-28)22-25-5-3-2-4-6-25/h2-14,21,28H,15-20,22H2,1H3/b14-9+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140492
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-be...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1cccc(F)c1 Show InChI InChI=1S/C31H32FN3O2/c1-23(36)34-19-14-26-11-12-29(21-30(26)34)35(31(37)13-10-24-8-5-9-27(32)20-24)28-15-17-33(18-16-28)22-25-6-3-2-4-7-25/h2-13,20-21,28H,14-19,22H2,1H3/b13-10+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140461
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-be...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1cc(C)cc(C)c1 Show InChI InChI=1S/C33H37N3O2/c1-24-19-25(2)21-28(20-24)9-12-33(38)36(31-11-10-29-13-18-35(26(3)37)32(29)22-31)30-14-16-34(17-15-30)23-27-7-5-4-6-8-27/h4-12,19-22,30H,13-18,23H2,1-3H3/b12-9+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140495
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-be...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C31H33N3O2/c1-24(35)33-21-16-27-13-14-29(22-30(27)33)34(31(36)15-12-25-8-4-2-5-9-25)28-17-19-32(20-18-28)23-26-10-6-3-7-11-26/h2-15,22,28H,16-21,23H2,1H3/b15-12+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140483
((E)-N-(1-Benzyl-piperidin-4-yl)-N-[1-(3-oxo-butyry...)Show SMILES CC(=O)CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C33H35N3O3/c1-25(37)22-33(39)35-21-16-28-13-14-30(23-31(28)35)36(32(38)15-12-26-8-4-2-5-9-26)29-17-19-34(20-18-29)24-27-10-6-3-7-11-27/h2-15,23,29H,16-22,24H2,1H3/b15-12+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140491
((6-{(1-Benzyl-piperidin-4-yl)-[(E)-(3-phenyl-acryl...)Show SMILES CCOC(=O)C(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C33H35N3O4/c1-2-40-33(39)32(38)35-22-17-27-14-15-29(23-30(27)35)36(31(37)16-13-25-9-5-3-6-10-25)28-18-20-34(21-19-28)24-26-11-7-4-8-12-26/h3-16,23,28H,2,17-22,24H2,1H3/b16-13+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140501
((E)-N-(1-Benzyl-piperidin-4-yl)-N-(1-methyl-2,3-di...)Show SMILES CN1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C30H33N3O/c1-31-19-16-26-13-14-28(22-29(26)31)33(30(34)15-12-24-8-4-2-5-9-24)27-17-20-32(21-18-27)23-25-10-6-3-7-11-25/h2-15,22,27H,16-21,23H2,1H3/b15-12+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140477
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-be...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1cccc(c1)S(=O)C(F)(F)F Show InChI InChI=1S/C32H32F3N3O3S/c1-23(39)37-19-14-26-11-12-28(21-30(26)37)38(27-15-17-36(18-16-27)22-25-6-3-2-4-7-25)31(40)13-10-24-8-5-9-29(20-24)42(41)32(33,34)35/h2-13,20-21,27H,14-19,22H2,1H3/b13-10+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140474
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-be...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C32H32F3N3O2/c1-23(39)37-19-14-26-11-12-29(21-30(26)37)38(28-15-17-36(18-16-28)22-25-6-3-2-4-7-25)31(40)13-10-24-8-5-9-27(20-24)32(33,34)35/h2-13,20-21,28H,14-19,22H2,1H3/b13-10+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 8.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140502
(3-Phenyl-propynoic acid (1-acetyl-2,3-dihydro-1H-i...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)C#Cc1ccccc1 Show InChI InChI=1S/C31H31N3O2/c1-24(35)33-21-16-27-13-14-29(22-30(27)33)34(31(36)15-12-25-8-4-2-5-9-25)28-17-19-32(20-18-28)23-26-10-6-3-7-11-26/h2-11,13-14,22,28H,16-21,23H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 9.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140498
((E)-N-(1-Acetyl-1,2,3,4-tetrahydro-quinolin-7-yl)-...)Show SMILES CC(=O)N1CCCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C32H35N3O2/c1-25(36)34-20-8-13-28-15-16-30(23-31(28)34)35(32(37)17-14-26-9-4-2-5-10-26)29-18-21-33(22-19-29)24-27-11-6-3-7-12-27/h2-7,9-12,14-17,23,29H,8,13,18-22,24H2,1H3/b17-14+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140473
((E)-4-Phenyl-but-3-enoic acid (1-acetyl-2,3-dihydr...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)C\C=C\c1ccccc1 Show InChI InChI=1S/C32H35N3O2/c1-25(36)34-22-17-28-15-16-30(23-31(28)34)35(32(37)14-8-13-26-9-4-2-5-10-26)29-18-20-33(21-19-29)24-27-11-6-3-7-12-27/h2-13,15-16,23,29H,14,17-22,24H2,1H3/b13-8+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140467
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-[3-(a...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(CCCN(CC=C)Cc1ccccc1)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C32H35N3O2/c1-3-20-33(25-28-13-8-5-9-14-28)21-10-22-35(32(37)18-15-27-11-6-4-7-12-27)30-17-16-29-19-23-34(26(2)36)31(29)24-30/h3-9,11-18,24H,1,10,19-23,25H2,2H3/b18-15+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140459
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(3-be...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(CCCNCc1ccccc1)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C29H31N3O2/c1-23(33)31-20-17-26-14-15-27(21-28(26)31)32(29(34)16-13-24-9-4-2-5-10-24)19-8-18-30-22-25-11-6-3-7-12-25/h2-7,9-16,21,30H,8,17-20,22H2,1H3/b16-13+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140490
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-be...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1ccncc1 Show InChI InChI=1S/C30H32N4O2/c1-23(35)33-20-13-26-8-9-28(21-29(26)33)34(30(36)10-7-24-11-16-31-17-12-24)27-14-18-32(19-15-27)22-25-5-3-2-4-6-25/h2-12,16-17,21,27H,13-15,18-20,22H2,1H3/b10-7+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140458
((E)-N-(1-Benzyl-piperidin-4-yl)-N-(1-methanesulfon...)Show SMILES CS(=O)(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C30H33N3O3S/c1-37(35,36)32-21-16-26-13-14-28(22-29(26)32)33(30(34)15-12-24-8-4-2-5-9-24)27-17-19-31(20-18-27)23-25-10-6-3-7-11-25/h2-15,22,27H,16-21,23H2,1H3/b15-12+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140510
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-be...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCCN(Cc2ccccc2)C1)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C31H33N3O2/c1-24(35)33-20-18-27-15-16-28(21-30(27)33)34(31(36)17-14-25-9-4-2-5-10-25)29-13-8-19-32(23-29)22-26-11-6-3-7-12-26/h2-7,9-12,14-17,21,29H,8,13,18-20,22-23H2,1H3/b17-14+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140493
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-be...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\C1N=CC=N1 |c:35,37| Show InChI InChI=1S/C28H31N5O2/c1-21(34)32-18-11-23-7-8-25(19-26(23)32)33(28(35)10-9-27-29-14-15-30-27)24-12-16-31(17-13-24)20-22-5-3-2-4-6-22/h2-10,14-15,19,24,27H,11-13,16-18,20H2,1H3/b10-9+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140496
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-be...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)C1)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C30H31N3O2/c1-23(34)32-19-16-26-13-14-27(20-29(26)32)33(30(35)15-12-24-8-4-2-5-9-24)28-17-18-31(22-28)21-25-10-6-3-7-11-25/h2-15,20,28H,16-19,21-22H2,1H3/b15-12+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.75E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140504
(CHEMBL22105 | N-(1-Acetyl-2,3-dihydro-1H-indol-6-y...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)CCc1ccccc1 Show InChI InChI=1S/C31H35N3O2/c1-24(35)33-21-16-27-13-14-29(22-30(27)33)34(31(36)15-12-25-8-4-2-5-9-25)28-17-19-32(20-18-28)23-26-10-6-3-7-11-26/h2-11,13-14,22,28H,12,15-21,23H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140488
((E)-N-(1-Benzyl-piperidin-4-yl)-N-(2,3-dihydro-1H-...)Show SMILES O=C(\C=C\c1ccccc1)N(C1CCN(Cc2ccccc2)CC1)c1ccc2CCNc2c1 Show InChI InChI=1S/C29H31N3O/c33-29(14-11-23-7-3-1-4-8-23)32(27-13-12-25-15-18-30-28(25)21-27)26-16-19-31(20-17-26)22-24-9-5-2-6-10-24/h1-14,21,26,30H,15-20,22H2/b14-11+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140463
((Z)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-be...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C/c1ccccc1 Show InChI InChI=1S/C31H33N3O2/c1-24(35)33-21-16-27-13-14-29(22-30(27)33)34(31(36)15-12-25-8-4-2-5-9-25)28-17-19-32(20-18-28)23-26-10-6-3-7-11-26/h2-15,22,28H,16-21,23H2,1H3/b15-12- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140508
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-ph...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(CCc2ccccc2)CC1)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C32H35N3O2/c1-25(36)34-23-17-28-13-14-30(24-31(28)34)35(32(37)15-12-26-8-4-2-5-9-26)29-18-21-33(22-19-29)20-16-27-10-6-3-7-11-27/h2-15,24,29H,16-23H2,1H3/b15-12+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140472
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-be...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(CC1)C(=O)c1ccccc1)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C31H31N3O3/c1-23(35)33-21-16-25-13-14-28(22-29(25)33)34(30(36)15-12-24-8-4-2-5-9-24)27-17-19-32(20-18-27)31(37)26-10-6-3-7-11-26/h2-15,22,27H,16-21H2,1H3/b15-12+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140482
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-be...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1ccccc1C(F)(F)F Show InChI InChI=1S/C32H32F3N3O2/c1-23(39)37-20-15-26-11-13-28(21-30(26)37)38(27-16-18-36(19-17-27)22-24-7-3-2-4-8-24)31(40)14-12-25-9-5-6-10-29(25)32(33,34)35/h2-14,21,27H,15-20,22H2,1H3/b14-12+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140484
(1-{6-[(1-Benzyl-piperidin-4-yl)-((E)-3-phenyl-ally...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C\C=C\c1ccccc1)C1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C31H35N3O/c1-25(35)33-22-16-28-14-15-30(23-31(28)33)34(19-8-13-26-9-4-2-5-10-26)29-17-20-32(21-18-29)24-27-11-6-3-7-12-27/h2-15,23,29H,16-22,24H2,1H3/b13-8+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140476
((E)-N-(1-Benzyl-piperidin-4-yl)-N-(2-oxo-2,3-dihyd...)Show SMILES O=C(\C=C\c1ccccc1)N(C1CCN(Cc2ccccc2)CC1)c1ccc2CC(=O)Nc2c1 Show InChI InChI=1S/C29H29N3O2/c33-28-19-24-12-13-26(20-27(24)30-28)32(29(34)14-11-22-7-3-1-4-8-22)25-15-17-31(18-16-25)21-23-9-5-2-6-10-23/h1-14,20,25H,15-19,21H2,(H,30,33)/b14-11+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140485
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-be...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C31H31Cl2N3O2/c1-22(37)35-16-11-25-8-9-29(20-30(25)35)36(31(38)10-7-24-17-26(32)19-27(33)18-24)28-12-14-34(15-13-28)21-23-5-3-2-4-6-23/h2-10,17-20,28H,11-16,21H2,1H3/b10-7+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140469
((E)-2-Phenyl-ethenesulfonic acid (1-acetyl-2,3-dih...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)S(=O)(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C30H33N3O3S/c1-24(34)32-20-14-27-12-13-29(22-30(27)32)33(37(35,36)21-17-25-8-4-2-5-9-25)28-15-18-31(19-16-28)23-26-10-6-3-7-11-26/h2-13,17,21-22,28H,14-16,18-20,23H2,1H3/b21-17+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140470
((E)-N-(1-Acetyl-1H-indol-6-yl)-N-(1-benzyl-piperid...)Show SMILES CC(=O)n1ccc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C31H31N3O2/c1-24(35)33-21-16-27-13-14-29(22-30(27)33)34(31(36)15-12-25-8-4-2-5-9-25)28-17-19-32(20-18-28)23-26-10-6-3-7-11-26/h2-16,21-22,28H,17-20,23H2,1H3/b15-12+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140466
((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-be...)Show SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1cccnc1 Show InChI InChI=1S/C30H32N4O2/c1-23(35)33-19-13-26-10-11-28(20-29(26)33)34(30(36)12-9-24-8-5-16-31-21-24)27-14-17-32(18-15-27)22-25-6-3-2-4-7-25/h2-12,16,20-21,27H,13-15,17-19,22H2,1H3/b12-9+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |
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