Compile Data Set for Download or QSAR

Found 53 hits Enz. Inhib. hit(s) with all data for entry = 50014992   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM50581713 (CHEMBL5085027) Show SMILES CCN(C)c1nc(=O)n(-c2cccnc2)c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PRMT5 in human HCT116-MTAP null cells assessed as reduction in symmetric dimethylation of arginine using SAM as substrate incubated for...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM50581712 (CHEMBL5078281) Show SMILES CCN(C)c1nc(=O)n(-c2ccccc2)c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PRMT5 in human HCT116-MTAP null cells assessed as reduction in symmetric dimethylation of arginine using SAM as substrate incubated for...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581712 (CHEMBL5078281) Show SMILES CCN(C)c1nc(=O)n(-c2ccccc2)c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581709 (CHEMBL5075691) Show SMILES CN(C)c1nc(=O)n(-c2cccc(C)c2)c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM50581711 (CHEMBL5078692) Show SMILES CN(C)c1nc(=O)n(-c2cccnc2)c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PRMT5 in human HCT116-MTAP null cells assessed as reduction in symmetric dimethylation of arginine using SAM as substrate incubated for...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581713 (CHEMBL5085027) Show SMILES CCN(C)c1nc(=O)n(-c2cccnc2)c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581711 (CHEMBL5078692) Show SMILES CN(C)c1nc(=O)n(-c2cccnc2)c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair				3D Structure (crystal)
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM507762 (7-chloro-4-(dimethylamino)-1-phenyl- quinazolin-2(...) Show SMILES CN(C)c1nc(=O)n(-c2ccccc2)c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM507762 (7-chloro-4-(dimethylamino)-1-phenyl- quinazolin-2(...) Show SMILES CN(C)c1nc(=O)n(-c2ccccc2)c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PRMT5 in human HCT116-MTAP null cells assessed as reduction in symmetric dimethylation of arginine using SAM as substrate incubated for...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581695 (CHEMBL5082697) Show SMILES CCN(C)c1nc(=O)[nH]c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581701 (CHEMBL5081076) Show SMILES Clc1ccc2c(nc(=O)[nH]c2c1)N1CCCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581707 (CHEMBL5086019) Show SMILES CN(C)c1nc(=O)n(CCO)c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair				3D Structure (crystal)
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581686 (CHEMBL5090541) Show SMILES CN(C)c1nc(=O)[nH]c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair				3D Structure (crystal)
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581708 (CHEMBL5084354) Show SMILES CN(C)c1nc(=O)n(C2CC2)c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM50581712 (CHEMBL5078281) Show SMILES CCN(C)c1nc(=O)n(-c2ccccc2)c2cc(Cl)ccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CYP1A2 in human liver microsomes				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581710 (CHEMBL5081015) Show SMILES CN(C)c1nc(=O)n(-c2ccccn2)c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50581713 (CHEMBL5085027) Show SMILES CCN(C)c1nc(=O)n(-c2cccnc2)c2cc(Cl)ccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CYP3A4 in human liver microsomes				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM507762 (7-chloro-4-(dimethylamino)-1-phenyl- quinazolin-2(...) Show SMILES CN(C)c1nc(=O)n(-c2ccccc2)c2cc(Cl)ccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CYP1A2 in human liver microsomes				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM50581711 (CHEMBL5078692) Show SMILES CN(C)c1nc(=O)n(-c2cccnc2)c2cc(Cl)ccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CYP1A2 in human liver microsomes				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM50581713 (CHEMBL5085027) Show SMILES CCN(C)c1nc(=O)n(-c2cccnc2)c2cc(Cl)ccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CYP1A2 in human liver microsomes				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM507762 (7-chloro-4-(dimethylamino)-1-phenyl- quinazolin-2(...) Show SMILES CN(C)c1nc(=O)n(-c2ccccc2)c2cc(Cl)ccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CYP3A4 in human liver microsomes				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50581712 (CHEMBL5078281) Show SMILES CCN(C)c1nc(=O)n(-c2ccccc2)c2cc(Cl)ccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CYP3A4 in human liver microsomes				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50581711 (CHEMBL5078692) Show SMILES CN(C)c1nc(=O)n(-c2cccnc2)c2cc(Cl)ccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CYP3A4 in human liver microsomes				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM507762 (7-chloro-4-(dimethylamino)-1-phenyl- quinazolin-2(...) Show SMILES CN(C)c1nc(=O)n(-c2ccccc2)c2cc(Cl)ccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of hERG by plate-based planar patch clamp method				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50581713 (CHEMBL5085027) Show SMILES CCN(C)c1nc(=O)n(-c2cccnc2)c2cc(Cl)ccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of hERG by plate-based planar patch clamp method				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50581711 (CHEMBL5078692) Show SMILES CN(C)c1nc(=O)n(-c2cccnc2)c2cc(Cl)ccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of hERG by plate-based planar patch clamp method				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50581712 (CHEMBL5078281) Show SMILES CCN(C)c1nc(=O)n(-c2ccccc2)c2cc(Cl)ccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of hERG by plate-based planar patch clamp method				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581703 (CHEMBL5091875) Show SMILES NC1CCN(C1)c1nc(=O)[nH]c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581689 (CHEMBL5082669) Show SMILES CNc1nc(=O)[nH]c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581702 (CHEMBL5088337) Show SMILES Clc1ccc2c(nc(=O)[nH]c2c1)N1CCCCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581698 (CHEMBL5078640) Show SMILES CN(Cc1ccccc1)c1nc(=O)[nH]c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581682 (CHEMBL5078655) Show SMILES COc1nc(-c2ccccc2)c2cc(Cl)ccc2n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair				3D Structure (crystal)
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581704 (CHEMBL5086613) Show SMILES CC(=O)NC1CCN(C1)c1nc(=O)[nH]c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581700 (CHEMBL5086150) Show SMILES Clc1ccc2c(nc(=O)[nH]c2c1)N1CCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581699 (CHEMBL5091008) Show SMILES CN(CCc1ccccc1)c1nc(=O)[nH]c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581697 (CHEMBL5088701) Show SMILES CN(c1ccccc1)c1nc(=O)[nH]c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581696 (CHEMBL5070989) Show SMILES CN(CCN)c1nc(=O)[nH]c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581694 (CHEMBL5078702) Show SMILES Clc1ccc2c(nc(=O)[nH]c2c1)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581693 (CHEMBL5072211) Show SMILES Clc1ccc2c(Oc3ccccc3)nc(=O)[nH]c2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581692 (CHEMBL5089094) Show SMILES COc1nc(=O)[nH]c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581691 (CHEMBL5084854) Show SMILES CC(=O)Nc1nc(=O)[nH]c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581690 (CHEMBL5090243) Show SMILES Nc1nc(=O)[nH]c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581688 (CHEMBL5087166) Show SMILES Clc1ccc2cnc(=O)[nH]c2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581687 (CHEMBL5092214) Show SMILES CN(C)c1nc(=O)[nH]c2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581705 (CHEMBL5094549) Show SMILES Clc1ccc2c(nc(=O)[nH]c2c1)N1CCc2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581706 (CHEMBL5089146) Show SMILES CN(C)c1nc(=O)n(C)c2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.87E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581683 (CHEMBL5078947) Show SMILES CCOc1nc(nc(=O)[nH]1)N(C)C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	2.06E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair				3D Structure (crystal)
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581685 (CHEMBL5074641) Show SMILES CCOc1nc(nc(=O)n1-c1ccccc1)N(C)C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.07E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581684 (CHEMBL5084976) Show SMILES CCOc1nc(nc(=O)n1C)N(C)C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM50581685 (CHEMBL5074641) Show SMILES CCOc1nc(nc(=O)n1-c1ccccc1)N(C)C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli assessed as dissociation constant by SPR...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00067 BindingDB Entry DOI: 10.7270/Q2RR234T
					More data for this Ligand-Target Pair

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