Found 88 hits Enz. Inhib. hit(s) with all data for entry = 50015398 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586222
(CHEMBL5082786)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3cccnc3C)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 2
(Homo sapiens (Human)) | BDBM50586222
(CHEMBL5082786)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3cccnc3C)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | 71 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD2-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586230
(CHEMBL5081350)Show SMILES COc1ccccc1NC(=O)CSc1nc2sc3CN(CCc3c2c(=O)n1Cc1ccco1)C(C)=O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50543359
(GSK620)Show InChI InChI=1S/C18H19N3O3/c1-19-17(23)15-9-13(16(22)20-14-7-8-14)11-21(18(15)24)10-12-5-3-2-4-6-12/h2-6,9,11,14H,7-8,10H2,1H3,(H,19,23)(H,20,22) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD2 (unknown origin) assessed as dissociation constant by TR-FRET method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586215
(CHEMBL5080392)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3cc(Cl)ccc3C)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50544300
(GSK046)Show SMILES C[C@H](Oc1cc(cc(F)c1NC(C)=O)C(=O)N[C@H]1CC[C@H](O)CC1)c1ccccc1 |wU:20.21,1.0,wD:17.17,(8.38,-8.55,;8.38,-7.03,;9.68,-6.27,;11.08,-7.03,;11.08,-8.55,;12.38,-9.42,;13.78,-8.55,;13.78,-7.03,;15.08,-6.27,;12.38,-6.27,;12.38,-4.64,;13.78,-3.88,;15.08,-4.64,;13.78,-2.36,;12.38,-10.94,;11.08,-11.7,;13.78,-11.7,;15.08,-10.94,;16.48,-11.7,;17.78,-10.94,;17.78,-9.42,;19.07,-8.55,;16.48,-8.55,;15.08,-9.42,;6.98,-6.27,;6.98,-4.64,;5.69,-3.88,;4.28,-4.64,;4.28,-6.27,;5.69,-7.03,)| Show InChI InChI=1S/C23H27FN2O4/c1-14(16-6-4-3-5-7-16)30-21-13-17(12-20(24)22(21)25-15(2)27)23(29)26-18-8-10-19(28)11-9-18/h3-7,12-14,18-19,28H,8-11H2,1-2H3,(H,25,27)(H,26,29)/t14-,18-,19-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | 98 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD2 (unknown origin) assessed as dissociation constant by TR-FRET method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586228
(CHEMBL5077541)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3ccccc3Cl)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 2
(Homo sapiens (Human)) | BDBM50586215
(CHEMBL5080392)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3cc(Cl)ccc3C)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD2-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50586222
(CHEMBL5082786)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3cccnc3C)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD4-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586226
(CHEMBL5069987)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3ccccc3)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586236
(CHEMBL5083228)Show SMILES CCOc1ccccc1NC(=O)CSc1nc2sc3CN(CCc3c2c(=O)n1Cc1ccco1)C(C)=O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586243
(CHEMBL5072385)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3cccc(c3)C(C)=O)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586242
(CHEMBL5074953)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3cc(F)ccc3F)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586238
(CHEMBL5089658)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3ccccc3F)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586239
(CHEMBL5094390)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3ccc(C)c(F)c3)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586233
(CHEMBL5077199)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3ccccc3C)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586227
(CHEMBL5079297)Show SMILES COc1cccc(NC(=O)CSc2nc3sc4CN(CCc4c3c(=O)n2Cc2ccco2)C(C)=O)c1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586244
(CHEMBL5086321)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3ccc(cc3)C(C)=O)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586215
(CHEMBL5080392)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3cc(Cl)ccc3C)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 325 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity to human partial length BRD3-BD2 (G306 to P416) expressed in bacterial system assessed as dissociation constant by BROMOscan method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586237
(CHEMBL5075819)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3ccc(F)cc3F)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586240
(CHEMBL5076502)Show SMILES CSc1cccc(NC(=O)CSc2nc3sc4CN(CCc4c3c(=O)n2Cc2ccco2)C(C)=O)c1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586224
(CHEMBL5085041)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3cc(Cl)ccc3C)n(-c3ccc(C)o3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586232
(CHEMBL5089846)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3ccc(F)cc3)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586229
(CHEMBL5089257)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3cccc(C)c3)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586247
(CHEMBL5075514)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3ccc(F)c(F)c3)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586235
(CHEMBL5094939)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3cccc(Cl)c3)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 490 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586241
(CHEMBL5090901)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3ccc(Cl)cc3)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 530 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586231
(CHEMBL5090190)Show SMILES COc1ccc(NC(=O)CSc2nc3sc4CN(CCc4c3c(=O)n2Cc2ccco2)C(C)=O)cc1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 570 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586234
(CHEMBL5081830)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3ccc(C)cc3)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 630 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586246
(CHEMBL5074555)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3ccc(F)c(Cl)c3)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 740 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50586215
(CHEMBL5080392)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3cc(Cl)ccc3C)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 775 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity to human partial length BRD4-BD2 (K333 to E460 residues) expressed in bacterial system assessed as dissociation constant by BROMOsca... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50586219
(CHEMBL5077591)Show SMILES COc1cc(cc(OC)c1OC)C(=O)C(=Cc1ccncc1)c1nc2ccccc2o1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD4-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586245
(CHEMBL5076250)Show SMILES CCOc1ccc(NC(=O)CSc2nc3sc4CN(CCc4c3c(=O)n2Cc2ccco2)C(C)=O)cc1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 880 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50586215
(CHEMBL5080392)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3cc(Cl)ccc3C)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD4-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50586216
(CHEMBL5078986)Show SMILES Cc1noc(C)c1-c1ccc(C)c(c1)S(=O)(=O)Nc1cccc(C)c1C | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD4-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50586220
(CHEMBL5084945)Show SMILES Cc1nn(CCO)c(C)c1-c1c(C)c(nc(N)c1C#N)-c1ccc(O)cc1 |(-1.41,-5.7,;-.32,-4.61,;1.19,-4.93,;1.96,-3.6,;3.5,-3.6,;4.27,-2.26,;5.81,-2.26,;.93,-2.45,;1.33,-.96,;-.48,-3.08,;-1.81,-2.31,;-1.81,-.77,;-.48,0,;-3.14,0,;-4.48,-.77,;-4.48,-2.32,;-5.81,-3.09,;-3.14,-3.08,;-3.14,-4.62,;-3.14,-6.16,;-3.14,1.54,;-4.48,2.31,;-4.47,3.85,;-3.14,4.62,;-3.14,6.16,;-1.81,3.85,;-1.8,2.31,)| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD4-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50586221
(CHEMBL5075052)Show SMILES Oc1ccc(cc1)N1C(=O)c2ccc(Oc3cccc(Oc4ccc5C(=O)N(C(=O)c5c4)c4ccc(O)cc4)c3)cc2C1=O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD4-BD1 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50586217
(CHEMBL5084236)Show SMILES CCc1cccc(C)c1NS(=O)(=O)c1cc(ccc1C)-c1c(C)noc1C | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD4-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586245
(CHEMBL5076250)Show SMILES CCOc1ccc(NC(=O)CSc2nc3sc4CN(CCc4c3c(=O)n2Cc2ccco2)C(C)=O)cc1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD1 domain (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50586222
(CHEMBL5082786)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3cccnc3C)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD4-BD1 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586244
(CHEMBL5086321)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3ccc(cc3)C(C)=O)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD1 domain (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50586218
(CHEMBL5093626)Show SMILES Cc1noc(C)c1-c1ccc(C)c(c1)S(=O)(=O)Nc1ccc(F)cc1C | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD4-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586231
(CHEMBL5090190)Show SMILES COc1ccc(NC(=O)CSc2nc3sc4CN(CCc4c3c(=O)n2Cc2ccco2)C(C)=O)cc1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD1 domain (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586229
(CHEMBL5089257)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3cccc(C)c3)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD1 domain (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50543359
(GSK620)Show InChI InChI=1S/C18H19N3O3/c1-19-17(23)15-9-13(16(22)20-14-7-8-14)11-21(18(15)24)10-12-5-3-2-4-6-12/h2-6,9,11,14H,7-8,10H2,1H3,(H,19,23)(H,20,22) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD1 (unknown origin) assessed as dissociation constant by TR-FRET method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 2
(Homo sapiens (Human)) | BDBM50586215
(CHEMBL5080392)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3cc(Cl)ccc3C)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity to human partial length BRD2-BD2 (E348 to D455) expressed in bacterial system assessed as dissociation constant by BROMOscan method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586228
(CHEMBL5077541)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3ccccc3Cl)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD1 domain (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586233
(CHEMBL5077199)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3ccccc3C)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD1 domain (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 3
(Homo sapiens (Human)) | BDBM50586235
(CHEMBL5094939)Show SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3cccc(Cl)c3)n(Cc3ccco3)c(=O)c21 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD3-BD1 domain (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50586221
(CHEMBL5075052)Show SMILES Oc1ccc(cc1)N1C(=O)c2ccc(Oc3cccc(Oc4ccc5C(=O)N(C(=O)c5c4)c4ccc(O)cc4)c3)cc2C1=O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD4-BD2 (unknown origin) incubated for 6 hrs by HTRF method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 |
More data for this Ligand-Target Pair | |