Found 40 hits Enz. Inhib. hit(s) with all data for entry = 50015516 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50587184
![PNG](/data/jpeg/tenK5058/BindingDB_50587184.png) (CHEMBL5089854)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)c1ccccc1)C(=O)Nc1ccccc1 |r| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50587186
![PNG](/data/jpeg/tenK5058/BindingDB_50587186.png) (CHEMBL5088034)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1cccc2ccccc12 |r| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM19149
![PNG](/data/jpeg/tenK1/BindingDB_19149.png) (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50587185
![PNG](/data/jpeg/tenK5058/BindingDB_50587185.png) (CHEMBL5093258)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccccc1 |r| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase
(Homo sapiens (Human)) | BDBM19149
![PNG](/data/jpeg/tenK1/BindingDB_19149.png) (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader ... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (crystal) |
Histone deacetylase
(Homo sapiens (Human)) | BDBM50587184
![PNG](/data/jpeg/tenK5058/BindingDB_50587184.png) (CHEMBL5089854)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)c1ccccc1)C(=O)Nc1ccccc1 |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader ... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)
(Homo sapiens (Human)) | BDBM50587186
![PNG](/data/jpeg/tenK5058/BindingDB_50587186.png) (CHEMBL5088034)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1cccc2ccccc12 |r| | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of C-terminal His-tagged recombinant human HDAC3 (1 to 428 residues)/N-terminal GST-tagged recombinant human NCoR2 (395 to 489 residues) c... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase
(Homo sapiens (Human)) | BDBM50587186
![PNG](/data/jpeg/tenK5058/BindingDB_50587186.png) (CHEMBL5088034)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1cccc2ccccc12 |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader ... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase
(Homo sapiens (Human)) | BDBM50587185
![PNG](/data/jpeg/tenK5058/BindingDB_50587185.png) (CHEMBL5093258)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccccc1 |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 75 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader ... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM19149
![PNG](/data/jpeg/tenK1/BindingDB_19149.png) (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank MMDB PDB Article PubMed
| n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of full length human C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(acetyl)-AMC as fluorogen... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (crystal) |
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)
(Homo sapiens (Human)) | BDBM19149
![PNG](/data/jpeg/tenK1/BindingDB_19149.png) (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of C-terminal His-tagged recombinant human HDAC3 (1 to 428 residues)/N-terminal GST-tagged recombinant human NCoR2 (395 to 489 residues) c... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM19149
![PNG](/data/jpeg/tenK1/BindingDB_19149.png) (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PDB Article PubMed
| n/a | n/a | 94 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HDAC1 (unknown origin) using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (crystal) |
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)
(Homo sapiens (Human)) | BDBM50587185
![PNG](/data/jpeg/tenK5058/BindingDB_50587185.png) (CHEMBL5093258)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccccc1 |r| | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 108 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of C-terminal His-tagged recombinant human HDAC3 (1 to 428 residues)/N-terminal GST-tagged recombinant human NCoR2 (395 to 489 residues) c... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)
(Homo sapiens (Human)) | BDBM50587184
![PNG](/data/jpeg/tenK5058/BindingDB_50587184.png) (CHEMBL5089854)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)c1ccccc1)C(=O)Nc1ccccc1 |r| | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 126 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of C-terminal His-tagged recombinant human HDAC3 (1 to 428 residues)/N-terminal GST-tagged recombinant human NCoR2 (395 to 489 residues) c... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50587186
![PNG](/data/jpeg/tenK5058/BindingDB_50587186.png) (CHEMBL5088034)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1cccc2ccccc12 |r| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HDAC1 (unknown origin) using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50587185
![PNG](/data/jpeg/tenK5058/BindingDB_50587185.png) (CHEMBL5093258)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccccc1 |r| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 172 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HDAC1 (unknown origin) using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50587184
![PNG](/data/jpeg/tenK5058/BindingDB_50587184.png) (CHEMBL5089854)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)c1ccccc1)C(=O)Nc1ccccc1 |r| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 198 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HDAC1 (unknown origin) using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50587185
![PNG](/data/jpeg/tenK5058/BindingDB_50587185.png) (CHEMBL5093258)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccccc1 |r| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of full length human C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(acetyl)-AMC as fluorogen... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50587186
![PNG](/data/jpeg/tenK5058/BindingDB_50587186.png) (CHEMBL5088034)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1cccc2ccccc12 |r| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of full length human C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(acetyl)-AMC as fluorogen... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 9
(Homo sapiens (Human)) | BDBM50587184
![PNG](/data/jpeg/tenK5058/BindingDB_50587184.png) (CHEMBL5089854)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)c1ccccc1)C(=O)Nc1ccccc1 |r| | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human C-terminal His-tagged HDAC9 (604 to 1066 residues) expressed in baculovirus infected Sf9 insect cells using Boc-Lys(acetyl)-AMC a... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 9
(Homo sapiens (Human)) | BDBM19149
![PNG](/data/jpeg/tenK1/BindingDB_19149.png) (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human C-terminal His-tagged HDAC9 (604 to 1066 residues) expressed in baculovirus infected Sf9 insect cells using Boc-Lys(acetyl)-AMC a... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 9
(Homo sapiens (Human)) | BDBM50587186
![PNG](/data/jpeg/tenK5058/BindingDB_50587186.png) (CHEMBL5088034)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1cccc2ccccc12 |r| | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human C-terminal His-tagged HDAC9 (604 to 1066 residues) expressed in baculovirus infected Sf9 insect cells using Boc-Lys(acetyl)-AMC a... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50587184
![PNG](/data/jpeg/tenK5058/BindingDB_50587184.png) (CHEMBL5089854)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)c1ccccc1)C(=O)Nc1ccccc1 |r| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of full length human C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(acetyl)-AMC as fluorogen... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 7
(Homo sapiens (Human)) | BDBM19149
![PNG](/data/jpeg/tenK1/BindingDB_19149.png) (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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| PDB Article PubMed
| n/a | n/a | >200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human N-terminal GST tagged HDAC7 (518 to end residues) expressed in baculovirus infected Sf9 insect cells using Boc-Lys(acetyl)-AMC as... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (crystal) |
Histone deacetylase 7
(Homo sapiens (Human)) | BDBM50587185
![PNG](/data/jpeg/tenK5058/BindingDB_50587185.png) (CHEMBL5093258)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccccc1 |r| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human N-terminal GST tagged HDAC7 (518 to end residues) expressed in baculovirus infected Sf9 insect cells using Boc-Lys(acetyl)-AMC as... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 7
(Homo sapiens (Human)) | BDBM50587184
![PNG](/data/jpeg/tenK5058/BindingDB_50587184.png) (CHEMBL5089854)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)c1ccccc1)C(=O)Nc1ccccc1 |r| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human N-terminal GST tagged HDAC7 (518 to end residues) expressed in baculovirus infected Sf9 insect cells using Boc-Lys(acetyl)-AMC as... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 7
(Homo sapiens (Human)) | BDBM50587186
![PNG](/data/jpeg/tenK5058/BindingDB_50587186.png) (CHEMBL5088034)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1cccc2ccccc12 |r| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human N-terminal GST tagged HDAC7 (518 to end residues) expressed in baculovirus infected Sf9 insect cells using Boc-Lys(acetyl)-AMC as... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 5
(Homo sapiens (Human)) | BDBM19149
![PNG](/data/jpeg/tenK1/BindingDB_19149.png) (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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| Article PubMed
| n/a | n/a | >200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human HDAC5 using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 5
(Homo sapiens (Human)) | BDBM50587184
![PNG](/data/jpeg/tenK5058/BindingDB_50587184.png) (CHEMBL5089854)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)c1ccccc1)C(=O)Nc1ccccc1 |r| | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human HDAC5 using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 5
(Homo sapiens (Human)) | BDBM50587186
![PNG](/data/jpeg/tenK5058/BindingDB_50587186.png) (CHEMBL5088034)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1cccc2ccccc12 |r| | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human HDAC5 using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 5
(Homo sapiens (Human)) | BDBM50587185
![PNG](/data/jpeg/tenK5058/BindingDB_50587185.png) (CHEMBL5093258)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccccc1 |r| | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human HDAC5 using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 9
(Homo sapiens (Human)) | BDBM50587185
![PNG](/data/jpeg/tenK5058/BindingDB_50587185.png) (CHEMBL5093258)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccccc1 |r| | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human C-terminal His-tagged HDAC9 (604 to 1066 residues) expressed in baculovirus infected Sf9 insect cells using Boc-Lys(acetyl)-AMC a... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 4
(Homo sapiens (Human)) | BDBM50587186
![PNG](/data/jpeg/tenK5058/BindingDB_50587186.png) (CHEMBL5088034)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1cccc2ccccc12 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human HDAC4 using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 4
(Homo sapiens (Human)) | BDBM50587185
![PNG](/data/jpeg/tenK5058/BindingDB_50587185.png) (CHEMBL5093258)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccccc1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human HDAC4 using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 4
(Homo sapiens (Human)) | BDBM50587184
![PNG](/data/jpeg/tenK5058/BindingDB_50587184.png) (CHEMBL5089854)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)c1ccccc1)C(=O)Nc1ccccc1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human HDAC4 using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM19149
![PNG](/data/jpeg/tenK1/BindingDB_19149.png) (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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| DrugBank PDB Article PubMed
| n/a | n/a | >200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of full length human HDAC2 using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (crystal) |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50587186
![PNG](/data/jpeg/tenK5058/BindingDB_50587186.png) (CHEMBL5088034)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1cccc2ccccc12 |r| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of full length human HDAC2 using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50587185
![PNG](/data/jpeg/tenK5058/BindingDB_50587185.png) (CHEMBL5093258)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccccc1 |r| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of full length human HDAC2 using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50587184
![PNG](/data/jpeg/tenK5058/BindingDB_50587184.png) (CHEMBL5089854)Show SMILES ONC(=O)CCCSC[C@H](NC(=O)c1ccccc1)C(=O)Nc1ccccc1 |r| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of full length human HDAC2 using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 4
(Homo sapiens (Human)) | BDBM19149
![PNG](/data/jpeg/tenK1/BindingDB_19149.png) (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human HDAC4 using Boc-Lys(acetyl)-AMC as fluorogenic substrate measured after 1 hr by flourescence plate reader method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113799 BindingDB Entry DOI: 10.7270/Q2V128Q6 |
More data for this Ligand-Target Pair | |