Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human)) | BDBM50587599![]() (CHEMBL5087453 | US11661419, Example 53 | US2023028...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of ITK (unknown origin) using BTK peptide as substrate preincubated for 30 mins followed by addition of substrate and measured after 60 mi... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00619 BindingDB Entry DOI: 10.7270/Q2736VT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human)) | BDBM50587592![]() (CHEMBL5090091 | US11661419, Example 7 | US20230280...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of ITK (unknown origin) using BTK peptide as substrate preincubated for 30 mins followed by addition of substrate and measured after 60 mi... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00619 BindingDB Entry DOI: 10.7270/Q2736VT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human)) | BDBM50587593![]() (CHEMBL5088468 | US11661419, Example 11 | US2023028...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of ITK (unknown origin) using BTK peptide as substrate preincubated for 30 mins followed by addition of substrate and measured after 60 mi... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00619 BindingDB Entry DOI: 10.7270/Q2736VT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human)) | BDBM50587596![]() (CHEMBL5086824 | US11661419, Example 36 | US2023028...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of ITK (unknown origin) using BTK peptide as substrate preincubated for 30 mins followed by addition of substrate and measured after 60 mi... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00619 BindingDB Entry DOI: 10.7270/Q2736VT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human)) | BDBM50587590![]() (CHEMBL5084598 | US11661419, Example 1 | US20230280...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of ITK (unknown origin) using BTK peptide as substrate preincubated for 30 mins followed by addition of substrate and measured after 60 mi... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00619 BindingDB Entry DOI: 10.7270/Q2736VT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human)) | BDBM50587598![]() (CHEMBL5074957 | US11661419, Example 46 | US2023028...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of ITK (unknown origin) using BTK peptide as substrate preincubated for 30 mins followed by addition of substrate and measured after 60 mi... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00619 BindingDB Entry DOI: 10.7270/Q2736VT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human)) | BDBM50587597![]() (CHEMBL5079033 | US11661419, Example 39 | US2023028...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of ITK (unknown origin) using BTK peptide as substrate preincubated for 30 mins followed by addition of substrate and measured after 60 mi... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00619 BindingDB Entry DOI: 10.7270/Q2736VT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human)) | BDBM50587594![]() (CHEMBL5082562 | US11661419, Example 18 | US2023028...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of ITK (unknown origin) using BTK peptide as substrate preincubated for 30 mins followed by addition of substrate and measured after 60 mi... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00619 BindingDB Entry DOI: 10.7270/Q2736VT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-2 (Homo sapiens (Human)) | BDBM50587599![]() (CHEMBL5087453 | US11661419, Example 53 | US2023028...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of IL-2 in CD3/CD28 activated human CD4+ve Th cells preincubated for 15 mins followed by addition of immuno-cult and measured after 24 hrs... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00619 BindingDB Entry DOI: 10.7270/Q2736VT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-2 (Homo sapiens (Human)) | BDBM50587592![]() (CHEMBL5090091 | US11661419, Example 7 | US20230280...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of IL-2 in CD3/CD28 activated human CD4+ve Th cells preincubated for 15 mins followed by addition of immuno-cult and measured after 24 hrs... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00619 BindingDB Entry DOI: 10.7270/Q2736VT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human)) | BDBM50587591![]() (CHEMBL5080834 | US11661419, Example 3 | US20230280...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of ITK (unknown origin) using BTK peptide as substrate preincubated for 30 mins followed by addition of substrate and measured after 60 mi... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00619 BindingDB Entry DOI: 10.7270/Q2736VT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-2 (Homo sapiens (Human)) | BDBM50587593![]() (CHEMBL5088468 | US11661419, Example 11 | US2023028...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of IL-2 in CD3/CD28 activated human CD4+ve Th cells preincubated for 15 mins followed by addition of immuno-cult and measured after 24 hrs... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00619 BindingDB Entry DOI: 10.7270/Q2736VT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-2 (Homo sapiens (Human)) | BDBM50587590![]() (CHEMBL5084598 | US11661419, Example 1 | US20230280...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of IL-2 in CD3/CD28 activated human CD4+ve Th cells preincubated for 15 mins followed by addition of immuno-cult and measured after 24 hrs... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00619 BindingDB Entry DOI: 10.7270/Q2736VT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-2 (Homo sapiens (Human)) | BDBM50587598![]() (CHEMBL5074957 | US11661419, Example 46 | US2023028...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of IL-2 in CD3/CD28 activated human CD4+ve Th cells preincubated for 15 mins followed by addition of immuno-cult and measured after 24 hrs... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00619 BindingDB Entry DOI: 10.7270/Q2736VT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-2 (Homo sapiens (Human)) | BDBM50587597![]() (CHEMBL5079033 | US11661419, Example 39 | US2023028...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 82 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of IL-2 in CD3/CD28 activated human CD4+ve Th cells preincubated for 15 mins followed by addition of immuno-cult and measured after 24 hrs... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00619 BindingDB Entry DOI: 10.7270/Q2736VT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-2 (Homo sapiens (Human)) | BDBM50587594![]() (CHEMBL5082562 | US11661419, Example 18 | US2023028...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 91 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of IL-2 in CD3/CD28 activated human CD4+ve Th cells preincubated for 15 mins followed by addition of immuno-cult and measured after 24 hrs... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00619 BindingDB Entry DOI: 10.7270/Q2736VT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-2 (Homo sapiens (Human)) | BDBM50587596![]() (CHEMBL5086824 | US11661419, Example 36 | US2023028...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 96 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of IL-2 in CD3/CD28 activated human CD4+ve Th cells preincubated for 15 mins followed by addition of immuno-cult and measured after 24 hrs... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00619 BindingDB Entry DOI: 10.7270/Q2736VT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-2 (Homo sapiens (Human)) | BDBM50587591![]() (CHEMBL5080834 | US11661419, Example 3 | US20230280...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 113 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of IL-2 in CD3/CD28 activated human CD4+ve Th cells preincubated for 15 mins followed by addition of immuno-cult and measured after 24 hrs... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00619 BindingDB Entry DOI: 10.7270/Q2736VT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human)) | BDBM50587595![]() (CHEMBL5083169 | US11661419, Example 23 | US2023028...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 124 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of ITK (unknown origin) using BTK peptide as substrate preincubated for 30 mins followed by addition of substrate and measured after 60 mi... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00619 BindingDB Entry DOI: 10.7270/Q2736VT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-2 (Homo sapiens (Human)) | BDBM50587595![]() (CHEMBL5083169 | US11661419, Example 23 | US2023028...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 304 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of IL-2 in CD3/CD28 activated human CD4+ve Th cells preincubated for 15 mins followed by addition of immuno-cult and measured after 24 hrs... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00619 BindingDB Entry DOI: 10.7270/Q2736VT6 | |||||||||||
More data for this Ligand-Target Pair |