Found 17 hits Enz. Inhib. hit(s) with all data for entry = 50025592 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat)) | BDBM50242449
(CHEMBL525025 | conantokin-G)Show SMILES [#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#7])=O)-[#6](-[#7])=O |r| Show InChI InChI=1S/C88H138N26O44/c1-7-34(6)61(77(138)103-41(12-10-20-98-88(96)97)63(124)107-48(23-35(78(139)140)79(141)142)69(130)100-40(11-8-9-19-89)64(125)113-54(31-115)76(137)104-45(62(95)123)28-57(93)118)114-75(136)47(22-33(4)5)106-70(131)49(24-36(80(143)144)81(145)146)109-67(128)44(14-17-56(92)117)102-74(135)53(29-58(94)119)112-73(134)51(26-38(84(151)152)85(153)154)110-66(127)43(13-16-55(91)116)101-68(129)46(21-32(2)3)105-71(132)52(27-39(86(155)156)87(157)158)111-72(133)50(25-37(82(147)148)83(149)150)108-65(126)42(15-18-60(121)122)99-59(120)30-90/h32-54,61,115H,7-31,89-90H2,1-6H3,(H2,91,116)(H2,92,117)(H2,93,118)(H2,94,119)(H2,95,123)(H,99,120)(H,100,130)(H,101,129)(H,102,135)(H,103,138)(H,104,137)(H,105,132)(H,106,131)(H,107,124)(H,108,126)(H,109,128)(H,110,127)(H,111,133)(H,112,134)(H,113,125)(H,114,136)(H,121,122)(H,139,140)(H,141,142)(H,143,144)(H,145,146)(H,147,148)(H,149,150)(H,151,152)(H,153,154)(H,155,156)(H,157,158)(H4,96,97,98)/t34-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,61-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of rat NMDA NR2B receptor expressed in xenopus oocytes coexpressing NMDA NR13b assessed as effect on glycine-induced current response at -... |
J Biol Chem 282: 36905-13 (2007)
Article DOI: 10.1074/jbc.M706611200
BindingDB Entry DOI: 10.7270/Q2NP246H |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat)) | BDBM50242446
(CHEMBL524338)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CN)[C@@H](C)CC)[C@@H](C)CC)C(O)=O |r,wU:136.143,112.123,95.105,87.89,64.74,43.49,31.32,4.4,wD:144.152,124.135,107.109,155.158,76.85,52.62,35.40,159.162,21.28,8.13,2.2,(62.58,-11.62,;62.58,-13.15,;63.91,-13.93,;65.24,-13.15,;63.91,-15.47,;62.58,-16.24,;61.25,-15.47,;61.25,-13.93,;59.91,-16.24,;59.91,-17.77,;61.25,-18.55,;61.25,-20.08,;62.58,-20.86,;62.58,-22.4,;58.59,-15.47,;57.25,-16.24,;57.25,-17.77,;55.92,-15.47,;54.58,-16.24,;53.25,-15.47,;53.25,-13.93,;51.92,-16.24,;51.92,-17.77,;53.67,-18.68,;55.03,-18.01,;56.13,-19.12,;55.37,-20.44,;53.88,-20.2,;50.58,-15.47,;49.25,-16.24,;49.25,-17.77,;47.91,-15.47,;46.58,-16.24,;45.25,-15.47,;45.25,-13.93,;43.91,-16.24,;43.91,-17.77,;45.25,-18.55,;45.25,-20.08,;46.58,-17.77,;42.59,-15.47,;41.24,-16.24,;41.24,-17.77,;39.92,-15.47,;39.92,-13.93,;41.24,-13.15,;41.24,-11.62,;39.92,-10.85,;42.59,-10.85,;38.57,-16.24,;37.25,-15.47,;37.25,-13.93,;35.92,-16.24,;35.92,-17.77,;37.78,-18.86,;39.11,-18.09,;40.44,-18.86,;40.44,-20.38,;41.76,-21.16,;39.11,-21.15,;37.78,-20.38,;34.58,-15.47,;33.25,-16.24,;33.25,-17.77,;31.91,-15.47,;31.91,-13.92,;32.71,-12.6,;31.96,-11.26,;30.42,-11.23,;32.76,-9.93,;34.26,-12.64,;35.01,-13.98,;35.06,-11.31,;30.58,-16.24,;29.24,-15.47,;29.24,-13.93,;27.91,-16.24,;27.91,-17.77,;29.24,-18.55,;29.24,-20.08,;30.58,-20.86,;30.58,-22.4,;29.24,-23.16,;31.91,-23.16,;26.58,-15.47,;25.24,-16.24,;25.24,-17.77,;23.91,-15.47,;22.57,-16.24,;21.25,-15.47,;21.25,-13.93,;19.92,-16.24,;18.58,-15.47,;17.25,-16.24,;17.25,-17.77,;15.92,-15.47,;15.92,-13.93,;16.71,-12.61,;15.97,-11.26,;14.43,-11.22,;16.77,-9.94,;18.26,-12.64,;19,-13.99,;19.06,-11.31,;14.58,-16.24,;13.25,-15.47,;13.25,-13.93,;11.91,-16.24,;11.91,-17.77,;10.58,-15.47,;9.24,-16.24,;9.24,-17.77,;7.91,-15.47,;7.91,-13.91,;7.16,-12.57,;7.94,-11.25,;7.2,-9.92,;5.67,-9.9,;4.92,-8.54,;4.88,-11.21,;5.62,-12.55,;6.59,-16.24,;5.25,-15.47,;5.25,-13.93,;3.92,-16.24,;3.91,-17.77,;4.67,-19.1,;3.9,-20.43,;2.37,-20.43,;4.67,-21.77,;6.22,-19.11,;6.99,-20.46,;7,-17.78,;2.58,-15.47,;1.25,-16.24,;1.25,-17.77,;-.09,-15.47,;-.09,-13.93,;1.25,-13.15,;2.58,-13.93,;1.25,-11.62,;-1.42,-16.24,;-2.75,-15.47,;-2.75,-13.93,;-4.09,-16.24,;-4.09,-17.77,;-2.75,-18.55,;-2.75,-20.08,;-4.09,-20.86,;-1.42,-20.86,;-5.42,-15.47,;-6.76,-16.24,;-6.76,-17.77,;-8.08,-15.47,;-9.42,-16.24,;23.91,-13.93,;25.24,-13.15,;22.57,-13.15,;22.57,-11.62,;47.91,-13.93,;49.25,-13.15,;46.58,-13.15,;46.58,-11.62,;65.24,-16.24,;66.58,-15.47,;65.24,-17.77,)| Show InChI InChI=1S/C101H150N26O39/c1-10-46(6)76(125-73(133)43-110-81(140)66(36-55(94(153)154)95(155)156)117-79(138)49(9)112-86(145)63(33-50-18-22-53(128)23-19-50)119-89(148)68(38-57(98(161)162)99(163)164)122-90(149)69(39-75(136)137)123-83(142)60(27-29-74(134)135)113-71(131)40-103)92(151)116-59(17-15-31-108-101(105)106)82(141)121-67(37-56(96(157)158)97(159)160)88(147)120-64(34-51-20-24-54(129)25-21-51)87(146)115-61(26-28-70(104)130)84(143)118-62(32-45(4)5)91(150)126-77(47(7)11-2)93(152)124-65(35-52-41-107-44-111-52)80(139)109-42-72(132)114-58(16-13-14-30-102)85(144)127-78(100(165)166)48(8)12-3/h18-25,41,44-49,55-69,76-78,128-129H,10-17,26-40,42-43,102-103H2,1-9H3,(H2,104,130)(H,107,111)(H,109,139)(H,110,140)(H,112,145)(H,113,131)(H,114,132)(H,115,146)(H,116,151)(H,117,138)(H,118,143)(H,119,148)(H,120,147)(H,121,141)(H,122,149)(H,123,142)(H,124,152)(H,125,133)(H,126,150)(H,127,144)(H,134,135)(H,136,137)(H,153,154)(H,155,156)(H,157,158)(H,159,160)(H,161,162)(H,163,164)(H,165,166)(H4,105,106,108)/t46-,47-,48-,49-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,76-,77-,78-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of rat NMDA NR2B receptor expressed in xenopus oocytes coexpressing NMDA NR13b assessed as effect on glycine-induced current response at -... |
J Biol Chem 282: 36905-13 (2007)
Article DOI: 10.1074/jbc.M706611200
BindingDB Entry DOI: 10.7270/Q2NP246H |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat)) | BDBM50242448
(CHEMBL526324)Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@H](CCC(O)=O)NC(=O)CN)C(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(C(O)=O)C(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(N)=O |r,wU:81.89,73.74,57.59,43.50,24.24,98.100,121.123,135.138,146.148,wD:61.71,52.54,29.41,12.20,4.4,109.111,130.133,140.142,75.77,(1.79,-21.01,;1.79,-19.47,;3.13,-18.7,;.46,-18.7,;.46,-17.15,;-.87,-16.38,;-2.2,-17.15,;-2.2,-18.69,;-3.53,-16.38,;-4.86,-17.15,;-6.2,-16.38,;-6.2,-14.84,;-7.52,-17.15,;-7.53,-18.69,;-6.74,-20.01,;-7.49,-21.35,;-9.03,-21.37,;-6.7,-22.67,;-5.2,-19.98,;-4.41,-21.3,;-4.45,-18.63,;-8.86,-16.37,;-10.19,-17.14,;-10.19,-18.68,;-11.52,-16.37,;-11.52,-14.84,;-12.87,-17.14,;-14.2,-16.37,;-14.2,-14.83,;-15.54,-17.14,;-15.54,-18.68,;-14.19,-19.45,;-12.96,-18.55,;-11.71,-19.45,;-12.18,-20.9,;-11.42,-22.23,;-12.18,-23.56,;-13.73,-23.57,;-14.49,-22.23,;-13.73,-20.9,;-16.87,-16.37,;-18.19,-17.13,;-18.19,-18.68,;-19.54,-16.36,;-19.54,-14.83,;-18.19,-14.06,;-18.19,-12.52,;-16.86,-11.75,;-16.86,-10.22,;-20.86,-17.13,;-22.19,-16.36,;-22.19,-14.82,;-23.53,-17.12,;-23.53,-18.67,;-24.86,-16.35,;-26.19,-17.12,;-26.19,-18.66,;-27.53,-16.35,;-28.86,-17.12,;-30.19,-16.35,;-30.19,-14.81,;-31.53,-17.12,;-31.53,-18.66,;-30.72,-19.97,;-31.46,-21.32,;-33.01,-21.37,;-30.66,-22.64,;-29.18,-19.93,;-28.38,-21.25,;-28.45,-18.58,;-32.86,-16.35,;-34.18,-17.11,;-34.18,-18.65,;-35.51,-16.34,;-35.43,-14.8,;-37.09,-14.46,;-37.78,-12.94,;-37.91,-15.92,;-36.77,-17.17,;-36.82,-18.69,;-35.52,-19.52,;-38.17,-19.43,;-39.49,-18.63,;-40.84,-19.37,;-42.16,-18.57,;-42.11,-17.03,;-43.5,-19.3,;-38.21,-20.97,;-36.91,-21.78,;-35.55,-21.04,;-36.95,-23.31,;-35.63,-24.11,;-27.53,-14.81,;-26.19,-14.05,;-28.86,-14.04,;1.79,-16.39,;1.79,-14.86,;3.13,-17.16,;4.45,-16.39,;4.45,-14.86,;5.79,-14.09,;5.79,-12.55,;7.13,-11.78,;7.13,-10.24,;5.8,-9.48,;8.46,-9.47,;5.79,-17.17,;5.79,-18.7,;7.13,-16.4,;8.45,-17.16,;8.45,-18.71,;9.2,-20.05,;8.41,-21.38,;6.87,-21.35,;9.16,-22.71,;10.75,-20.07,;11.5,-21.42,;11.54,-18.75,;9.79,-16.4,;9.79,-14.86,;11.13,-17.17,;12.45,-16.4,;12.45,-14.87,;13.79,-14.1,;13.79,-12.56,;15.13,-11.79,;15.13,-10.25,;13.79,-17.17,;13.79,-18.71,;15.12,-16.41,;16.45,-17.17,;16.45,-18.72,;17.78,-16.4,;17.78,-14.87,;19.12,-17.18,;20.45,-16.41,;20.45,-14.88,;21.78,-17.18,;21.78,-18.73,;23.11,-16.42,;24.45,-17.19,;24.45,-18.73,;25.78,-19.5,;25.78,-16.42,;25.78,-14.88,;27.11,-17.19,;28.44,-16.42,;28.44,-14.89,;29.78,-14.11,;31.11,-14.89,;29.78,-12.58,;29.78,-17.19,;31.1,-16.42,;29.78,-18.73,)| Show InChI InChI=1S/C91H141N27O36/c1-38(2)26-56(78(136)110-53(20-15-25-99-91(97)98)76(134)114-59(30-48(87(147)148)88(149)150)79(137)109-51(18-11-13-23-92)74(132)103-40(5)69(127)102-41(6)72(130)116-61(37-119)81(139)111-55(68(96)126)32-63(95)121)107-65(123)35-101-73(131)58(29-47(85(143)144)86(145)146)112-71(129)42(7)104-77(135)57(27-44-34-100-50-17-10-9-16-46(44)50)113-75(133)52(19-12-14-24-93)108-70(128)43(8)105-83(141)67(39(3)4)117-80(138)60(31-49(89(151)152)90(153)154)115-82(140)62-28-45(120)36-118(62)84(142)54(21-22-66(124)125)106-64(122)33-94/h9-10,16-17,34,38-43,45,47-49,51-62,67,100,119-120H,11-15,18-33,35-37,92-94H2,1-8H3,(H2,95,121)(H2,96,126)(H,101,131)(H,102,127)(H,103,132)(H,104,135)(H,105,141)(H,106,122)(H,107,123)(H,108,128)(H,109,137)(H,110,136)(H,111,139)(H,112,129)(H,113,133)(H,114,134)(H,115,140)(H,116,130)(H,117,138)(H,124,125)(H,143,144)(H,145,146)(H,147,148)(H,149,150)(H,151,152)(H,153,154)(H4,97,98,99)/t40-,41-,42-,43-,45+,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,67-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of rat NMDA NR2B receptor expressed in xenopus oocytes coexpressing NMDA NR13b assessed as effect on glycine-induced current response at -... |
J Biol Chem 282: 36905-13 (2007)
Article DOI: 10.1074/jbc.M706611200
BindingDB Entry DOI: 10.7270/Q2NP246H |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat)) | BDBM50242447
(CHEMBL525783)Show SMILES [#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6@@H](-[#8])-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-[#6](-[#8])=O)-[#6@@H](-[#6])-[#6]-[#6])-[#6](-[#8])=O |r| Show InChI InChI=1S/C108H159N25O41/c1-9-50(5)82(131-85(145)53(8)118-93(153)74(43-61(101(161)162)102(163)164)124-84(144)52(7)117-92(152)72(40-55-21-27-58(135)28-22-55)127-97(157)76(45-63(105(169)170)106(171)172)130-98(158)77-42-60(137)48-133(77)100(160)69(32-34-80(140)141)123-86(146)64(111)46-81(142)143)99(159)122-67(18-15-37-115-108(113)114)89(149)129-75(44-62(103(165)166)104(167)168)96(156)128-73(41-56-23-29-59(136)30-24-56)95(155)121-68(31-33-78(112)138)90(150)125-70(38-49(3)4)94(154)120-66(17-12-14-36-110)88(148)126-71(39-54-19-25-57(134)26-20-54)87(147)116-47-79(139)119-65(16-11-13-35-109)91(151)132-83(107(173)174)51(6)10-2/h19-30,49-53,60-77,82-83,134-137H,9-18,31-48,109-111H2,1-8H3,(H2,112,138)(H,116,147)(H,117,152)(H,118,153)(H,119,139)(H,120,154)(H,121,155)(H,122,159)(H,123,146)(H,124,144)(H,125,150)(H,126,148)(H,127,157)(H,128,156)(H,129,149)(H,130,158)(H,131,145)(H,132,151)(H,140,141)(H,142,143)(H,161,162)(H,163,164)(H,165,166)(H,167,168)(H,169,170)(H,171,172)(H,173,174)(H4,113,114,115)/t50-,51-,52-,53-,60+,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,82-,83-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of rat NMDA NR2B receptor expressed in xenopus oocytes coexpressing NMDA NR13b assessed as effect on glycine-induced current response at -... |
J Biol Chem 282: 36905-13 (2007)
Article DOI: 10.1074/jbc.M706611200
BindingDB Entry DOI: 10.7270/Q2NP246H |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2D
(Rattus norvegicus (Rat)) | BDBM50242447
(CHEMBL525783)Show SMILES [#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6@@H](-[#8])-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-[#6](-[#8])=O)-[#6@@H](-[#6])-[#6]-[#6])-[#6](-[#8])=O |r| Show InChI InChI=1S/C108H159N25O41/c1-9-50(5)82(131-85(145)53(8)118-93(153)74(43-61(101(161)162)102(163)164)124-84(144)52(7)117-92(152)72(40-55-21-27-58(135)28-22-55)127-97(157)76(45-63(105(169)170)106(171)172)130-98(158)77-42-60(137)48-133(77)100(160)69(32-34-80(140)141)123-86(146)64(111)46-81(142)143)99(159)122-67(18-15-37-115-108(113)114)89(149)129-75(44-62(103(165)166)104(167)168)96(156)128-73(41-56-23-29-59(136)30-24-56)95(155)121-68(31-33-78(112)138)90(150)125-70(38-49(3)4)94(154)120-66(17-12-14-36-110)88(148)126-71(39-54-19-25-57(134)26-20-54)87(147)116-47-79(139)119-65(16-11-13-35-109)91(151)132-83(107(173)174)51(6)10-2/h19-30,49-53,60-77,82-83,134-137H,9-18,31-48,109-111H2,1-8H3,(H2,112,138)(H,116,147)(H,117,152)(H,118,153)(H,119,139)(H,120,154)(H,121,155)(H,122,159)(H,123,146)(H,124,144)(H,125,150)(H,126,148)(H,127,157)(H,128,156)(H,129,149)(H,130,158)(H,131,145)(H,132,151)(H,140,141)(H,142,143)(H,161,162)(H,163,164)(H,165,166)(H,167,168)(H,169,170)(H,171,172)(H,173,174)(H4,113,114,115)/t50-,51-,52-,53-,60+,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,82-,83-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of rat NMDA NR2D receptor expressed in xenopus oocytes coexpressing NMDA NR13b assessed as effect on glycine-induced current response at -... |
J Biol Chem 282: 36905-13 (2007)
Article DOI: 10.1074/jbc.M706611200
BindingDB Entry DOI: 10.7270/Q2NP246H |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2D
(Rattus norvegicus (Rat)) | BDBM50242446
(CHEMBL524338)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CN)[C@@H](C)CC)[C@@H](C)CC)C(O)=O |r,wU:136.143,112.123,95.105,87.89,64.74,43.49,31.32,4.4,wD:144.152,124.135,107.109,155.158,76.85,52.62,35.40,159.162,21.28,8.13,2.2,(62.58,-11.62,;62.58,-13.15,;63.91,-13.93,;65.24,-13.15,;63.91,-15.47,;62.58,-16.24,;61.25,-15.47,;61.25,-13.93,;59.91,-16.24,;59.91,-17.77,;61.25,-18.55,;61.25,-20.08,;62.58,-20.86,;62.58,-22.4,;58.59,-15.47,;57.25,-16.24,;57.25,-17.77,;55.92,-15.47,;54.58,-16.24,;53.25,-15.47,;53.25,-13.93,;51.92,-16.24,;51.92,-17.77,;53.67,-18.68,;55.03,-18.01,;56.13,-19.12,;55.37,-20.44,;53.88,-20.2,;50.58,-15.47,;49.25,-16.24,;49.25,-17.77,;47.91,-15.47,;46.58,-16.24,;45.25,-15.47,;45.25,-13.93,;43.91,-16.24,;43.91,-17.77,;45.25,-18.55,;45.25,-20.08,;46.58,-17.77,;42.59,-15.47,;41.24,-16.24,;41.24,-17.77,;39.92,-15.47,;39.92,-13.93,;41.24,-13.15,;41.24,-11.62,;39.92,-10.85,;42.59,-10.85,;38.57,-16.24,;37.25,-15.47,;37.25,-13.93,;35.92,-16.24,;35.92,-17.77,;37.78,-18.86,;39.11,-18.09,;40.44,-18.86,;40.44,-20.38,;41.76,-21.16,;39.11,-21.15,;37.78,-20.38,;34.58,-15.47,;33.25,-16.24,;33.25,-17.77,;31.91,-15.47,;31.91,-13.92,;32.71,-12.6,;31.96,-11.26,;30.42,-11.23,;32.76,-9.93,;34.26,-12.64,;35.01,-13.98,;35.06,-11.31,;30.58,-16.24,;29.24,-15.47,;29.24,-13.93,;27.91,-16.24,;27.91,-17.77,;29.24,-18.55,;29.24,-20.08,;30.58,-20.86,;30.58,-22.4,;29.24,-23.16,;31.91,-23.16,;26.58,-15.47,;25.24,-16.24,;25.24,-17.77,;23.91,-15.47,;22.57,-16.24,;21.25,-15.47,;21.25,-13.93,;19.92,-16.24,;18.58,-15.47,;17.25,-16.24,;17.25,-17.77,;15.92,-15.47,;15.92,-13.93,;16.71,-12.61,;15.97,-11.26,;14.43,-11.22,;16.77,-9.94,;18.26,-12.64,;19,-13.99,;19.06,-11.31,;14.58,-16.24,;13.25,-15.47,;13.25,-13.93,;11.91,-16.24,;11.91,-17.77,;10.58,-15.47,;9.24,-16.24,;9.24,-17.77,;7.91,-15.47,;7.91,-13.91,;7.16,-12.57,;7.94,-11.25,;7.2,-9.92,;5.67,-9.9,;4.92,-8.54,;4.88,-11.21,;5.62,-12.55,;6.59,-16.24,;5.25,-15.47,;5.25,-13.93,;3.92,-16.24,;3.91,-17.77,;4.67,-19.1,;3.9,-20.43,;2.37,-20.43,;4.67,-21.77,;6.22,-19.11,;6.99,-20.46,;7,-17.78,;2.58,-15.47,;1.25,-16.24,;1.25,-17.77,;-.09,-15.47,;-.09,-13.93,;1.25,-13.15,;2.58,-13.93,;1.25,-11.62,;-1.42,-16.24,;-2.75,-15.47,;-2.75,-13.93,;-4.09,-16.24,;-4.09,-17.77,;-2.75,-18.55,;-2.75,-20.08,;-4.09,-20.86,;-1.42,-20.86,;-5.42,-15.47,;-6.76,-16.24,;-6.76,-17.77,;-8.08,-15.47,;-9.42,-16.24,;23.91,-13.93,;25.24,-13.15,;22.57,-13.15,;22.57,-11.62,;47.91,-13.93,;49.25,-13.15,;46.58,-13.15,;46.58,-11.62,;65.24,-16.24,;66.58,-15.47,;65.24,-17.77,)| Show InChI InChI=1S/C101H150N26O39/c1-10-46(6)76(125-73(133)43-110-81(140)66(36-55(94(153)154)95(155)156)117-79(138)49(9)112-86(145)63(33-50-18-22-53(128)23-19-50)119-89(148)68(38-57(98(161)162)99(163)164)122-90(149)69(39-75(136)137)123-83(142)60(27-29-74(134)135)113-71(131)40-103)92(151)116-59(17-15-31-108-101(105)106)82(141)121-67(37-56(96(157)158)97(159)160)88(147)120-64(34-51-20-24-54(129)25-21-51)87(146)115-61(26-28-70(104)130)84(143)118-62(32-45(4)5)91(150)126-77(47(7)11-2)93(152)124-65(35-52-41-107-44-111-52)80(139)109-42-72(132)114-58(16-13-14-30-102)85(144)127-78(100(165)166)48(8)12-3/h18-25,41,44-49,55-69,76-78,128-129H,10-17,26-40,42-43,102-103H2,1-9H3,(H2,104,130)(H,107,111)(H,109,139)(H,110,140)(H,112,145)(H,113,131)(H,114,132)(H,115,146)(H,116,151)(H,117,138)(H,118,143)(H,119,148)(H,120,147)(H,121,141)(H,122,149)(H,123,142)(H,124,152)(H,125,133)(H,126,150)(H,127,144)(H,134,135)(H,136,137)(H,153,154)(H,155,156)(H,157,158)(H,159,160)(H,161,162)(H,163,164)(H,165,166)(H4,105,106,108)/t46-,47-,48-,49-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,76-,77-,78-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of rat NMDA NR2D receptor expressed in xenopus oocytes coexpressing NMDA NR13b assessed as effect on glycine-induced current response at -... |
J Biol Chem 282: 36905-13 (2007)
Article DOI: 10.1074/jbc.M706611200
BindingDB Entry DOI: 10.7270/Q2NP246H |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2A
(Rattus norvegicus (Rat)) | BDBM50242450
(CHEMBL524886 | conantokin-R)Show SMILES [#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#16]-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6]-[#7])-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#16])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#16])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](-[#8])=O |r| Show InChI InChI=1S/C126H202N34O48S3/c1-15-57(8)93(115(189)141-62(13)96(170)145-71(24-16-19-36-127)100(174)136-51-89(165)143-83(52-209)111(185)147-73(26-18-21-38-129)104(178)157-92(56(6)7)114(188)154-80(48-86(131)162)108(182)156-84(53-210)112(186)155-82(43-63-29-31-64(161)32-30-63)116(190)160-40-23-28-85(160)125(207)208)159-110(184)81(49-87(132)163)150-99(173)65(44-66(117(191)192)118(193)194)70(27-22-39-135-126(133)134)144-95(169)60(11)139-105(179)76(42-54(2)3)151-106(180)77(45-67(119(195)196)120(197)198)149-98(172)59(10)137-94(168)58(9)138-101(175)75(35-41-211-14)148-102(176)72(25-17-20-37-128)146-97(171)61(12)140-113(187)91(55(4)5)158-109(183)79(47-69(123(203)204)124(205)206)153-107(181)78(46-68(121(199)200)122(201)202)152-103(177)74(33-34-90(166)167)142-88(164)50-130/h29-32,54-62,65-85,91-93,161,209-210H,15-28,33-53,127-130H2,1-14H3,(H2,131,162)(H2,132,163)(H,136,174)(H,137,168)(H,138,175)(H,139,179)(H,140,187)(H,141,189)(H,142,164)(H,143,165)(H,144,169)(H,145,170)(H,146,171)(H,147,185)(H,148,176)(H,149,172)(H,150,173)(H,151,180)(H,152,177)(H,153,181)(H,154,188)(H,155,186)(H,156,182)(H,157,178)(H,158,183)(H,159,184)(H,166,167)(H,191,192)(H,193,194)(H,195,196)(H,197,198)(H,199,200)(H,201,202)(H,203,204)(H,205,206)(H,207,208)(H4,133,134,135)/t57-,58-,59-,60-,61-,62-,65?,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,91-,92-,93-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of rat NMDA NR2A receptor expressed in xenopus oocytes coexpressing NMDA NR13b assessed as effect on glycine-induced current response at -... |
J Biol Chem 282: 36905-13 (2007)
Article DOI: 10.1074/jbc.M706611200
BindingDB Entry DOI: 10.7270/Q2NP246H |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2D
(Rattus norvegicus (Rat)) | BDBM50242449
(CHEMBL525025 | conantokin-G)Show SMILES [#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#7])=O)-[#6](-[#7])=O |r| Show InChI InChI=1S/C88H138N26O44/c1-7-34(6)61(77(138)103-41(12-10-20-98-88(96)97)63(124)107-48(23-35(78(139)140)79(141)142)69(130)100-40(11-8-9-19-89)64(125)113-54(31-115)76(137)104-45(62(95)123)28-57(93)118)114-75(136)47(22-33(4)5)106-70(131)49(24-36(80(143)144)81(145)146)109-67(128)44(14-17-56(92)117)102-74(135)53(29-58(94)119)112-73(134)51(26-38(84(151)152)85(153)154)110-66(127)43(13-16-55(91)116)101-68(129)46(21-32(2)3)105-71(132)52(27-39(86(155)156)87(157)158)111-72(133)50(25-37(82(147)148)83(149)150)108-65(126)42(15-18-60(121)122)99-59(120)30-90/h32-54,61,115H,7-31,89-90H2,1-6H3,(H2,91,116)(H2,92,117)(H2,93,118)(H2,94,119)(H2,95,123)(H,99,120)(H,100,130)(H,101,129)(H,102,135)(H,103,138)(H,104,137)(H,105,132)(H,106,131)(H,107,124)(H,108,126)(H,109,128)(H,110,127)(H,111,133)(H,112,134)(H,113,125)(H,114,136)(H,121,122)(H,139,140)(H,141,142)(H,143,144)(H,145,146)(H,147,148)(H,149,150)(H,151,152)(H,153,154)(H,155,156)(H,157,158)(H4,96,97,98)/t34-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,61-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of rat NMDA NR2D receptor expressed in xenopus oocytes coexpressing NMDA NR13b assessed as effect on glycine-induced current response at -... |
J Biol Chem 282: 36905-13 (2007)
Article DOI: 10.1074/jbc.M706611200
BindingDB Entry DOI: 10.7270/Q2NP246H |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2C
(Rattus norvegicus (Rat)) | BDBM50242449
(CHEMBL525025 | conantokin-G)Show SMILES [#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#7])=O)-[#6](-[#7])=O |r| Show InChI InChI=1S/C88H138N26O44/c1-7-34(6)61(77(138)103-41(12-10-20-98-88(96)97)63(124)107-48(23-35(78(139)140)79(141)142)69(130)100-40(11-8-9-19-89)64(125)113-54(31-115)76(137)104-45(62(95)123)28-57(93)118)114-75(136)47(22-33(4)5)106-70(131)49(24-36(80(143)144)81(145)146)109-67(128)44(14-17-56(92)117)102-74(135)53(29-58(94)119)112-73(134)51(26-38(84(151)152)85(153)154)110-66(127)43(13-16-55(91)116)101-68(129)46(21-32(2)3)105-71(132)52(27-39(86(155)156)87(157)158)111-72(133)50(25-37(82(147)148)83(149)150)108-65(126)42(15-18-60(121)122)99-59(120)30-90/h32-54,61,115H,7-31,89-90H2,1-6H3,(H2,91,116)(H2,92,117)(H2,93,118)(H2,94,119)(H2,95,123)(H,99,120)(H,100,130)(H,101,129)(H,102,135)(H,103,138)(H,104,137)(H,105,132)(H,106,131)(H,107,124)(H,108,126)(H,109,128)(H,110,127)(H,111,133)(H,112,134)(H,113,125)(H,114,136)(H,121,122)(H,139,140)(H,141,142)(H,143,144)(H,145,146)(H,147,148)(H,149,150)(H,151,152)(H,153,154)(H,155,156)(H,157,158)(H4,96,97,98)/t34-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,61-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of rat NMDA NR2C receptor expressed in xenopus oocytes coexpressing NMDA NR13b assessed as effect on glycine-induced current response at -... |
J Biol Chem 282: 36905-13 (2007)
Article DOI: 10.1074/jbc.M706611200
BindingDB Entry DOI: 10.7270/Q2NP246H |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat)) | BDBM50242450
(CHEMBL524886 | conantokin-R)Show SMILES [#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#16]-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6]-[#7])-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#16])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#16])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](-[#8])=O |r| Show InChI InChI=1S/C126H202N34O48S3/c1-15-57(8)93(115(189)141-62(13)96(170)145-71(24-16-19-36-127)100(174)136-51-89(165)143-83(52-209)111(185)147-73(26-18-21-38-129)104(178)157-92(56(6)7)114(188)154-80(48-86(131)162)108(182)156-84(53-210)112(186)155-82(43-63-29-31-64(161)32-30-63)116(190)160-40-23-28-85(160)125(207)208)159-110(184)81(49-87(132)163)150-99(173)65(44-66(117(191)192)118(193)194)70(27-22-39-135-126(133)134)144-95(169)60(11)139-105(179)76(42-54(2)3)151-106(180)77(45-67(119(195)196)120(197)198)149-98(172)59(10)137-94(168)58(9)138-101(175)75(35-41-211-14)148-102(176)72(25-17-20-37-128)146-97(171)61(12)140-113(187)91(55(4)5)158-109(183)79(47-69(123(203)204)124(205)206)153-107(181)78(46-68(121(199)200)122(201)202)152-103(177)74(33-34-90(166)167)142-88(164)50-130/h29-32,54-62,65-85,91-93,161,209-210H,15-28,33-53,127-130H2,1-14H3,(H2,131,162)(H2,132,163)(H,136,174)(H,137,168)(H,138,175)(H,139,179)(H,140,187)(H,141,189)(H,142,164)(H,143,165)(H,144,169)(H,145,170)(H,146,171)(H,147,185)(H,148,176)(H,149,172)(H,150,173)(H,151,180)(H,152,177)(H,153,181)(H,154,188)(H,155,186)(H,156,182)(H,157,178)(H,158,183)(H,159,184)(H,166,167)(H,191,192)(H,193,194)(H,195,196)(H,197,198)(H,199,200)(H,201,202)(H,203,204)(H,205,206)(H,207,208)(H4,133,134,135)/t57-,58-,59-,60-,61-,62-,65?,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,91-,92-,93-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of rat NMDA NR2B receptor expressed in xenopus oocytes coexpressing NMDA NR13b assessed as effect on glycine-induced current response at -... |
J Biol Chem 282: 36905-13 (2007)
Article DOI: 10.1074/jbc.M706611200
BindingDB Entry DOI: 10.7270/Q2NP246H |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2C
(Rattus norvegicus (Rat)) | BDBM50242450
(CHEMBL524886 | conantokin-R)Show SMILES [#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#16]-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6]-[#7])-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#16])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#16])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](-[#8])=O |r| Show InChI InChI=1S/C126H202N34O48S3/c1-15-57(8)93(115(189)141-62(13)96(170)145-71(24-16-19-36-127)100(174)136-51-89(165)143-83(52-209)111(185)147-73(26-18-21-38-129)104(178)157-92(56(6)7)114(188)154-80(48-86(131)162)108(182)156-84(53-210)112(186)155-82(43-63-29-31-64(161)32-30-63)116(190)160-40-23-28-85(160)125(207)208)159-110(184)81(49-87(132)163)150-99(173)65(44-66(117(191)192)118(193)194)70(27-22-39-135-126(133)134)144-95(169)60(11)139-105(179)76(42-54(2)3)151-106(180)77(45-67(119(195)196)120(197)198)149-98(172)59(10)137-94(168)58(9)138-101(175)75(35-41-211-14)148-102(176)72(25-17-20-37-128)146-97(171)61(12)140-113(187)91(55(4)5)158-109(183)79(47-69(123(203)204)124(205)206)153-107(181)78(46-68(121(199)200)122(201)202)152-103(177)74(33-34-90(166)167)142-88(164)50-130/h29-32,54-62,65-85,91-93,161,209-210H,15-28,33-53,127-130H2,1-14H3,(H2,131,162)(H2,132,163)(H,136,174)(H,137,168)(H,138,175)(H,139,179)(H,140,187)(H,141,189)(H,142,164)(H,143,165)(H,144,169)(H,145,170)(H,146,171)(H,147,185)(H,148,176)(H,149,172)(H,150,173)(H,151,180)(H,152,177)(H,153,181)(H,154,188)(H,155,186)(H,156,182)(H,157,178)(H,158,183)(H,159,184)(H,166,167)(H,191,192)(H,193,194)(H,195,196)(H,197,198)(H,199,200)(H,201,202)(H,203,204)(H,205,206)(H,207,208)(H4,133,134,135)/t57-,58-,59-,60-,61-,62-,65?,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,91-,92-,93-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of rat NMDA NR2C receptor expressed in xenopus oocytes coexpressing NMDA NR13b assessed as effect on glycine-induced current response at -... |
J Biol Chem 282: 36905-13 (2007)
Article DOI: 10.1074/jbc.M706611200
BindingDB Entry DOI: 10.7270/Q2NP246H |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2D
(Rattus norvegicus (Rat)) | BDBM50242448
(CHEMBL526324)Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@H](CCC(O)=O)NC(=O)CN)C(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(C(O)=O)C(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(N)=O |r,wU:81.89,73.74,57.59,43.50,24.24,98.100,121.123,135.138,146.148,wD:61.71,52.54,29.41,12.20,4.4,109.111,130.133,140.142,75.77,(1.79,-21.01,;1.79,-19.47,;3.13,-18.7,;.46,-18.7,;.46,-17.15,;-.87,-16.38,;-2.2,-17.15,;-2.2,-18.69,;-3.53,-16.38,;-4.86,-17.15,;-6.2,-16.38,;-6.2,-14.84,;-7.52,-17.15,;-7.53,-18.69,;-6.74,-20.01,;-7.49,-21.35,;-9.03,-21.37,;-6.7,-22.67,;-5.2,-19.98,;-4.41,-21.3,;-4.45,-18.63,;-8.86,-16.37,;-10.19,-17.14,;-10.19,-18.68,;-11.52,-16.37,;-11.52,-14.84,;-12.87,-17.14,;-14.2,-16.37,;-14.2,-14.83,;-15.54,-17.14,;-15.54,-18.68,;-14.19,-19.45,;-12.96,-18.55,;-11.71,-19.45,;-12.18,-20.9,;-11.42,-22.23,;-12.18,-23.56,;-13.73,-23.57,;-14.49,-22.23,;-13.73,-20.9,;-16.87,-16.37,;-18.19,-17.13,;-18.19,-18.68,;-19.54,-16.36,;-19.54,-14.83,;-18.19,-14.06,;-18.19,-12.52,;-16.86,-11.75,;-16.86,-10.22,;-20.86,-17.13,;-22.19,-16.36,;-22.19,-14.82,;-23.53,-17.12,;-23.53,-18.67,;-24.86,-16.35,;-26.19,-17.12,;-26.19,-18.66,;-27.53,-16.35,;-28.86,-17.12,;-30.19,-16.35,;-30.19,-14.81,;-31.53,-17.12,;-31.53,-18.66,;-30.72,-19.97,;-31.46,-21.32,;-33.01,-21.37,;-30.66,-22.64,;-29.18,-19.93,;-28.38,-21.25,;-28.45,-18.58,;-32.86,-16.35,;-34.18,-17.11,;-34.18,-18.65,;-35.51,-16.34,;-35.43,-14.8,;-37.09,-14.46,;-37.78,-12.94,;-37.91,-15.92,;-36.77,-17.17,;-36.82,-18.69,;-35.52,-19.52,;-38.17,-19.43,;-39.49,-18.63,;-40.84,-19.37,;-42.16,-18.57,;-42.11,-17.03,;-43.5,-19.3,;-38.21,-20.97,;-36.91,-21.78,;-35.55,-21.04,;-36.95,-23.31,;-35.63,-24.11,;-27.53,-14.81,;-26.19,-14.05,;-28.86,-14.04,;1.79,-16.39,;1.79,-14.86,;3.13,-17.16,;4.45,-16.39,;4.45,-14.86,;5.79,-14.09,;5.79,-12.55,;7.13,-11.78,;7.13,-10.24,;5.8,-9.48,;8.46,-9.47,;5.79,-17.17,;5.79,-18.7,;7.13,-16.4,;8.45,-17.16,;8.45,-18.71,;9.2,-20.05,;8.41,-21.38,;6.87,-21.35,;9.16,-22.71,;10.75,-20.07,;11.5,-21.42,;11.54,-18.75,;9.79,-16.4,;9.79,-14.86,;11.13,-17.17,;12.45,-16.4,;12.45,-14.87,;13.79,-14.1,;13.79,-12.56,;15.13,-11.79,;15.13,-10.25,;13.79,-17.17,;13.79,-18.71,;15.12,-16.41,;16.45,-17.17,;16.45,-18.72,;17.78,-16.4,;17.78,-14.87,;19.12,-17.18,;20.45,-16.41,;20.45,-14.88,;21.78,-17.18,;21.78,-18.73,;23.11,-16.42,;24.45,-17.19,;24.45,-18.73,;25.78,-19.5,;25.78,-16.42,;25.78,-14.88,;27.11,-17.19,;28.44,-16.42,;28.44,-14.89,;29.78,-14.11,;31.11,-14.89,;29.78,-12.58,;29.78,-17.19,;31.1,-16.42,;29.78,-18.73,)| Show InChI InChI=1S/C91H141N27O36/c1-38(2)26-56(78(136)110-53(20-15-25-99-91(97)98)76(134)114-59(30-48(87(147)148)88(149)150)79(137)109-51(18-11-13-23-92)74(132)103-40(5)69(127)102-41(6)72(130)116-61(37-119)81(139)111-55(68(96)126)32-63(95)121)107-65(123)35-101-73(131)58(29-47(85(143)144)86(145)146)112-71(129)42(7)104-77(135)57(27-44-34-100-50-17-10-9-16-46(44)50)113-75(133)52(19-12-14-24-93)108-70(128)43(8)105-83(141)67(39(3)4)117-80(138)60(31-49(89(151)152)90(153)154)115-82(140)62-28-45(120)36-118(62)84(142)54(21-22-66(124)125)106-64(122)33-94/h9-10,16-17,34,38-43,45,47-49,51-62,67,100,119-120H,11-15,18-33,35-37,92-94H2,1-8H3,(H2,95,121)(H2,96,126)(H,101,131)(H,102,127)(H,103,132)(H,104,135)(H,105,141)(H,106,122)(H,107,123)(H,108,128)(H,109,137)(H,110,136)(H,111,139)(H,112,129)(H,113,133)(H,114,134)(H,115,140)(H,116,130)(H,117,138)(H,124,125)(H,143,144)(H,145,146)(H,147,148)(H,149,150)(H,151,152)(H,153,154)(H4,97,98,99)/t40-,41-,42-,43-,45+,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,67-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of rat NMDA NR2D receptor expressed in xenopus oocytes coexpressing NMDA NR13b assessed as effect on glycine-induced current response at -... |
J Biol Chem 282: 36905-13 (2007)
Article DOI: 10.1074/jbc.M706611200
BindingDB Entry DOI: 10.7270/Q2NP246H |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2A
(Rattus norvegicus (Rat)) | BDBM50242449
(CHEMBL525025 | conantokin-G)Show SMILES [#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#7])=O)-[#6](-[#7])=O |r| Show InChI InChI=1S/C88H138N26O44/c1-7-34(6)61(77(138)103-41(12-10-20-98-88(96)97)63(124)107-48(23-35(78(139)140)79(141)142)69(130)100-40(11-8-9-19-89)64(125)113-54(31-115)76(137)104-45(62(95)123)28-57(93)118)114-75(136)47(22-33(4)5)106-70(131)49(24-36(80(143)144)81(145)146)109-67(128)44(14-17-56(92)117)102-74(135)53(29-58(94)119)112-73(134)51(26-38(84(151)152)85(153)154)110-66(127)43(13-16-55(91)116)101-68(129)46(21-32(2)3)105-71(132)52(27-39(86(155)156)87(157)158)111-72(133)50(25-37(82(147)148)83(149)150)108-65(126)42(15-18-60(121)122)99-59(120)30-90/h32-54,61,115H,7-31,89-90H2,1-6H3,(H2,91,116)(H2,92,117)(H2,93,118)(H2,94,119)(H2,95,123)(H,99,120)(H,100,130)(H,101,129)(H,102,135)(H,103,138)(H,104,137)(H,105,132)(H,106,131)(H,107,124)(H,108,126)(H,109,128)(H,110,127)(H,111,133)(H,112,134)(H,113,125)(H,114,136)(H,121,122)(H,139,140)(H,141,142)(H,143,144)(H,145,146)(H,147,148)(H,149,150)(H,151,152)(H,153,154)(H,155,156)(H,157,158)(H4,96,97,98)/t34-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,61-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of rat NMDA NR2A receptor expressed in xenopus oocytes coexpressing NMDA NR13b assessed as effect on glycine-induced current response at -... |
J Biol Chem 282: 36905-13 (2007)
Article DOI: 10.1074/jbc.M706611200
BindingDB Entry DOI: 10.7270/Q2NP246H |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2A
(Rattus norvegicus (Rat)) | BDBM50242448
(CHEMBL526324)Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@H](CCC(O)=O)NC(=O)CN)C(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(C(O)=O)C(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(N)=O |r,wU:81.89,73.74,57.59,43.50,24.24,98.100,121.123,135.138,146.148,wD:61.71,52.54,29.41,12.20,4.4,109.111,130.133,140.142,75.77,(1.79,-21.01,;1.79,-19.47,;3.13,-18.7,;.46,-18.7,;.46,-17.15,;-.87,-16.38,;-2.2,-17.15,;-2.2,-18.69,;-3.53,-16.38,;-4.86,-17.15,;-6.2,-16.38,;-6.2,-14.84,;-7.52,-17.15,;-7.53,-18.69,;-6.74,-20.01,;-7.49,-21.35,;-9.03,-21.37,;-6.7,-22.67,;-5.2,-19.98,;-4.41,-21.3,;-4.45,-18.63,;-8.86,-16.37,;-10.19,-17.14,;-10.19,-18.68,;-11.52,-16.37,;-11.52,-14.84,;-12.87,-17.14,;-14.2,-16.37,;-14.2,-14.83,;-15.54,-17.14,;-15.54,-18.68,;-14.19,-19.45,;-12.96,-18.55,;-11.71,-19.45,;-12.18,-20.9,;-11.42,-22.23,;-12.18,-23.56,;-13.73,-23.57,;-14.49,-22.23,;-13.73,-20.9,;-16.87,-16.37,;-18.19,-17.13,;-18.19,-18.68,;-19.54,-16.36,;-19.54,-14.83,;-18.19,-14.06,;-18.19,-12.52,;-16.86,-11.75,;-16.86,-10.22,;-20.86,-17.13,;-22.19,-16.36,;-22.19,-14.82,;-23.53,-17.12,;-23.53,-18.67,;-24.86,-16.35,;-26.19,-17.12,;-26.19,-18.66,;-27.53,-16.35,;-28.86,-17.12,;-30.19,-16.35,;-30.19,-14.81,;-31.53,-17.12,;-31.53,-18.66,;-30.72,-19.97,;-31.46,-21.32,;-33.01,-21.37,;-30.66,-22.64,;-29.18,-19.93,;-28.38,-21.25,;-28.45,-18.58,;-32.86,-16.35,;-34.18,-17.11,;-34.18,-18.65,;-35.51,-16.34,;-35.43,-14.8,;-37.09,-14.46,;-37.78,-12.94,;-37.91,-15.92,;-36.77,-17.17,;-36.82,-18.69,;-35.52,-19.52,;-38.17,-19.43,;-39.49,-18.63,;-40.84,-19.37,;-42.16,-18.57,;-42.11,-17.03,;-43.5,-19.3,;-38.21,-20.97,;-36.91,-21.78,;-35.55,-21.04,;-36.95,-23.31,;-35.63,-24.11,;-27.53,-14.81,;-26.19,-14.05,;-28.86,-14.04,;1.79,-16.39,;1.79,-14.86,;3.13,-17.16,;4.45,-16.39,;4.45,-14.86,;5.79,-14.09,;5.79,-12.55,;7.13,-11.78,;7.13,-10.24,;5.8,-9.48,;8.46,-9.47,;5.79,-17.17,;5.79,-18.7,;7.13,-16.4,;8.45,-17.16,;8.45,-18.71,;9.2,-20.05,;8.41,-21.38,;6.87,-21.35,;9.16,-22.71,;10.75,-20.07,;11.5,-21.42,;11.54,-18.75,;9.79,-16.4,;9.79,-14.86,;11.13,-17.17,;12.45,-16.4,;12.45,-14.87,;13.79,-14.1,;13.79,-12.56,;15.13,-11.79,;15.13,-10.25,;13.79,-17.17,;13.79,-18.71,;15.12,-16.41,;16.45,-17.17,;16.45,-18.72,;17.78,-16.4,;17.78,-14.87,;19.12,-17.18,;20.45,-16.41,;20.45,-14.88,;21.78,-17.18,;21.78,-18.73,;23.11,-16.42,;24.45,-17.19,;24.45,-18.73,;25.78,-19.5,;25.78,-16.42,;25.78,-14.88,;27.11,-17.19,;28.44,-16.42,;28.44,-14.89,;29.78,-14.11,;31.11,-14.89,;29.78,-12.58,;29.78,-17.19,;31.1,-16.42,;29.78,-18.73,)| Show InChI InChI=1S/C91H141N27O36/c1-38(2)26-56(78(136)110-53(20-15-25-99-91(97)98)76(134)114-59(30-48(87(147)148)88(149)150)79(137)109-51(18-11-13-23-92)74(132)103-40(5)69(127)102-41(6)72(130)116-61(37-119)81(139)111-55(68(96)126)32-63(95)121)107-65(123)35-101-73(131)58(29-47(85(143)144)86(145)146)112-71(129)42(7)104-77(135)57(27-44-34-100-50-17-10-9-16-46(44)50)113-75(133)52(19-12-14-24-93)108-70(128)43(8)105-83(141)67(39(3)4)117-80(138)60(31-49(89(151)152)90(153)154)115-82(140)62-28-45(120)36-118(62)84(142)54(21-22-66(124)125)106-64(122)33-94/h9-10,16-17,34,38-43,45,47-49,51-62,67,100,119-120H,11-15,18-33,35-37,92-94H2,1-8H3,(H2,95,121)(H2,96,126)(H,101,131)(H,102,127)(H,103,132)(H,104,135)(H,105,141)(H,106,122)(H,107,123)(H,108,128)(H,109,137)(H,110,136)(H,111,139)(H,112,129)(H,113,133)(H,114,134)(H,115,140)(H,116,130)(H,117,138)(H,124,125)(H,143,144)(H,145,146)(H,147,148)(H,149,150)(H,151,152)(H,153,154)(H4,97,98,99)/t40-,41-,42-,43-,45+,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,67-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of rat NMDA NR2A receptor expressed in xenopus oocytes coexpressing NMDA NR13b assessed as effect on glycine-induced current response at -... |
J Biol Chem 282: 36905-13 (2007)
Article DOI: 10.1074/jbc.M706611200
BindingDB Entry DOI: 10.7270/Q2NP246H |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2A
(Rattus norvegicus (Rat)) | BDBM50242446
(CHEMBL524338)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C(O)=O)C(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CN)[C@@H](C)CC)[C@@H](C)CC)C(O)=O |r,wU:136.143,112.123,95.105,87.89,64.74,43.49,31.32,4.4,wD:144.152,124.135,107.109,155.158,76.85,52.62,35.40,159.162,21.28,8.13,2.2,(62.58,-11.62,;62.58,-13.15,;63.91,-13.93,;65.24,-13.15,;63.91,-15.47,;62.58,-16.24,;61.25,-15.47,;61.25,-13.93,;59.91,-16.24,;59.91,-17.77,;61.25,-18.55,;61.25,-20.08,;62.58,-20.86,;62.58,-22.4,;58.59,-15.47,;57.25,-16.24,;57.25,-17.77,;55.92,-15.47,;54.58,-16.24,;53.25,-15.47,;53.25,-13.93,;51.92,-16.24,;51.92,-17.77,;53.67,-18.68,;55.03,-18.01,;56.13,-19.12,;55.37,-20.44,;53.88,-20.2,;50.58,-15.47,;49.25,-16.24,;49.25,-17.77,;47.91,-15.47,;46.58,-16.24,;45.25,-15.47,;45.25,-13.93,;43.91,-16.24,;43.91,-17.77,;45.25,-18.55,;45.25,-20.08,;46.58,-17.77,;42.59,-15.47,;41.24,-16.24,;41.24,-17.77,;39.92,-15.47,;39.92,-13.93,;41.24,-13.15,;41.24,-11.62,;39.92,-10.85,;42.59,-10.85,;38.57,-16.24,;37.25,-15.47,;37.25,-13.93,;35.92,-16.24,;35.92,-17.77,;37.78,-18.86,;39.11,-18.09,;40.44,-18.86,;40.44,-20.38,;41.76,-21.16,;39.11,-21.15,;37.78,-20.38,;34.58,-15.47,;33.25,-16.24,;33.25,-17.77,;31.91,-15.47,;31.91,-13.92,;32.71,-12.6,;31.96,-11.26,;30.42,-11.23,;32.76,-9.93,;34.26,-12.64,;35.01,-13.98,;35.06,-11.31,;30.58,-16.24,;29.24,-15.47,;29.24,-13.93,;27.91,-16.24,;27.91,-17.77,;29.24,-18.55,;29.24,-20.08,;30.58,-20.86,;30.58,-22.4,;29.24,-23.16,;31.91,-23.16,;26.58,-15.47,;25.24,-16.24,;25.24,-17.77,;23.91,-15.47,;22.57,-16.24,;21.25,-15.47,;21.25,-13.93,;19.92,-16.24,;18.58,-15.47,;17.25,-16.24,;17.25,-17.77,;15.92,-15.47,;15.92,-13.93,;16.71,-12.61,;15.97,-11.26,;14.43,-11.22,;16.77,-9.94,;18.26,-12.64,;19,-13.99,;19.06,-11.31,;14.58,-16.24,;13.25,-15.47,;13.25,-13.93,;11.91,-16.24,;11.91,-17.77,;10.58,-15.47,;9.24,-16.24,;9.24,-17.77,;7.91,-15.47,;7.91,-13.91,;7.16,-12.57,;7.94,-11.25,;7.2,-9.92,;5.67,-9.9,;4.92,-8.54,;4.88,-11.21,;5.62,-12.55,;6.59,-16.24,;5.25,-15.47,;5.25,-13.93,;3.92,-16.24,;3.91,-17.77,;4.67,-19.1,;3.9,-20.43,;2.37,-20.43,;4.67,-21.77,;6.22,-19.11,;6.99,-20.46,;7,-17.78,;2.58,-15.47,;1.25,-16.24,;1.25,-17.77,;-.09,-15.47,;-.09,-13.93,;1.25,-13.15,;2.58,-13.93,;1.25,-11.62,;-1.42,-16.24,;-2.75,-15.47,;-2.75,-13.93,;-4.09,-16.24,;-4.09,-17.77,;-2.75,-18.55,;-2.75,-20.08,;-4.09,-20.86,;-1.42,-20.86,;-5.42,-15.47,;-6.76,-16.24,;-6.76,-17.77,;-8.08,-15.47,;-9.42,-16.24,;23.91,-13.93,;25.24,-13.15,;22.57,-13.15,;22.57,-11.62,;47.91,-13.93,;49.25,-13.15,;46.58,-13.15,;46.58,-11.62,;65.24,-16.24,;66.58,-15.47,;65.24,-17.77,)| Show InChI InChI=1S/C101H150N26O39/c1-10-46(6)76(125-73(133)43-110-81(140)66(36-55(94(153)154)95(155)156)117-79(138)49(9)112-86(145)63(33-50-18-22-53(128)23-19-50)119-89(148)68(38-57(98(161)162)99(163)164)122-90(149)69(39-75(136)137)123-83(142)60(27-29-74(134)135)113-71(131)40-103)92(151)116-59(17-15-31-108-101(105)106)82(141)121-67(37-56(96(157)158)97(159)160)88(147)120-64(34-51-20-24-54(129)25-21-51)87(146)115-61(26-28-70(104)130)84(143)118-62(32-45(4)5)91(150)126-77(47(7)11-2)93(152)124-65(35-52-41-107-44-111-52)80(139)109-42-72(132)114-58(16-13-14-30-102)85(144)127-78(100(165)166)48(8)12-3/h18-25,41,44-49,55-69,76-78,128-129H,10-17,26-40,42-43,102-103H2,1-9H3,(H2,104,130)(H,107,111)(H,109,139)(H,110,140)(H,112,145)(H,113,131)(H,114,132)(H,115,146)(H,116,151)(H,117,138)(H,118,143)(H,119,148)(H,120,147)(H,121,141)(H,122,149)(H,123,142)(H,124,152)(H,125,133)(H,126,150)(H,127,144)(H,134,135)(H,136,137)(H,153,154)(H,155,156)(H,157,158)(H,159,160)(H,161,162)(H,163,164)(H,165,166)(H4,105,106,108)/t46-,47-,48-,49-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,76-,77-,78-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of rat NMDA NR2A receptor expressed in xenopus oocytes coexpressing NMDA NR13b assessed as effect on glycine-induced current response at -... |
J Biol Chem 282: 36905-13 (2007)
Article DOI: 10.1074/jbc.M706611200
BindingDB Entry DOI: 10.7270/Q2NP246H |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2D
(Rattus norvegicus (Rat)) | BDBM50242450
(CHEMBL524886 | conantokin-R)Show SMILES [#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#16]-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6]-[#7])-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#16])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#16])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](-[#8])=O |r| Show InChI InChI=1S/C126H202N34O48S3/c1-15-57(8)93(115(189)141-62(13)96(170)145-71(24-16-19-36-127)100(174)136-51-89(165)143-83(52-209)111(185)147-73(26-18-21-38-129)104(178)157-92(56(6)7)114(188)154-80(48-86(131)162)108(182)156-84(53-210)112(186)155-82(43-63-29-31-64(161)32-30-63)116(190)160-40-23-28-85(160)125(207)208)159-110(184)81(49-87(132)163)150-99(173)65(44-66(117(191)192)118(193)194)70(27-22-39-135-126(133)134)144-95(169)60(11)139-105(179)76(42-54(2)3)151-106(180)77(45-67(119(195)196)120(197)198)149-98(172)59(10)137-94(168)58(9)138-101(175)75(35-41-211-14)148-102(176)72(25-17-20-37-128)146-97(171)61(12)140-113(187)91(55(4)5)158-109(183)79(47-69(123(203)204)124(205)206)153-107(181)78(46-68(121(199)200)122(201)202)152-103(177)74(33-34-90(166)167)142-88(164)50-130/h29-32,54-62,65-85,91-93,161,209-210H,15-28,33-53,127-130H2,1-14H3,(H2,131,162)(H2,132,163)(H,136,174)(H,137,168)(H,138,175)(H,139,179)(H,140,187)(H,141,189)(H,142,164)(H,143,165)(H,144,169)(H,145,170)(H,146,171)(H,147,185)(H,148,176)(H,149,172)(H,150,173)(H,151,180)(H,152,177)(H,153,181)(H,154,188)(H,155,186)(H,156,182)(H,157,178)(H,158,183)(H,159,184)(H,166,167)(H,191,192)(H,193,194)(H,195,196)(H,197,198)(H,199,200)(H,201,202)(H,203,204)(H,205,206)(H,207,208)(H4,133,134,135)/t57-,58-,59-,60-,61-,62-,65?,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,91-,92-,93-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of rat NMDA NR2D receptor expressed in xenopus oocytes coexpressing NMDA NR13b assessed as effect on glycine-induced current response at -... |
J Biol Chem 282: 36905-13 (2007)
Article DOI: 10.1074/jbc.M706611200
BindingDB Entry DOI: 10.7270/Q2NP246H |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2A
(Rattus norvegicus (Rat)) | BDBM50242447
(CHEMBL525783)Show SMILES [#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6](-[#8])=O)-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6@@H](-[#8])-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-[#6](-[#8])=O)-[#6@@H](-[#6])-[#6]-[#6])-[#6](-[#8])=O |r| Show InChI InChI=1S/C108H159N25O41/c1-9-50(5)82(131-85(145)53(8)118-93(153)74(43-61(101(161)162)102(163)164)124-84(144)52(7)117-92(152)72(40-55-21-27-58(135)28-22-55)127-97(157)76(45-63(105(169)170)106(171)172)130-98(158)77-42-60(137)48-133(77)100(160)69(32-34-80(140)141)123-86(146)64(111)46-81(142)143)99(159)122-67(18-15-37-115-108(113)114)89(149)129-75(44-62(103(165)166)104(167)168)96(156)128-73(41-56-23-29-59(136)30-24-56)95(155)121-68(31-33-78(112)138)90(150)125-70(38-49(3)4)94(154)120-66(17-12-14-36-110)88(148)126-71(39-54-19-25-57(134)26-20-54)87(147)116-47-79(139)119-65(16-11-13-35-109)91(151)132-83(107(173)174)51(6)10-2/h19-30,49-53,60-77,82-83,134-137H,9-18,31-48,109-111H2,1-8H3,(H2,112,138)(H,116,147)(H,117,152)(H,118,153)(H,119,139)(H,120,154)(H,121,155)(H,122,159)(H,123,146)(H,124,144)(H,125,150)(H,126,148)(H,127,157)(H,128,156)(H,129,149)(H,130,158)(H,131,145)(H,132,151)(H,140,141)(H,142,143)(H,161,162)(H,163,164)(H,165,166)(H,167,168)(H,169,170)(H,171,172)(H,173,174)(H4,113,114,115)/t50-,51-,52-,53-,60+,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,82-,83-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of rat NMDA NR2A receptor expressed in xenopus oocytes coexpressing NMDA NR13b assessed as effect on glycine-induced current response at -... |
J Biol Chem 282: 36905-13 (2007)
Article DOI: 10.1074/jbc.M706611200
BindingDB Entry DOI: 10.7270/Q2NP246H |
More data for this
Ligand-Target Pair | |
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