Found 102 hits Enz. Inhib. hit(s) with all data for entry = 50028201 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248494
(CHEMBL490968 | N-(Pyridin-4-ylmethyl)-2-(1-(3-(tri...)Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H16F3N5/c22-21(23,24)16-4-3-5-17(12-16)29-14-20(27-28-29)18-6-1-2-7-19(18)26-13-15-8-10-25-11-9-15/h1-12,14,26H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Binding affinity to VEGFR2 (unknown origin) at IC90 in presence of ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248494
(CHEMBL490968 | N-(Pyridin-4-ylmethyl)-2-(1-(3-(tri...)Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H16F3N5/c22-21(23,24)16-4-3-5-17(12-16)29-14-20(27-28-29)18-6-1-2-7-19(18)26-13-15-8-10-25-11-9-15/h1-12,14,26H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Binding affinity to VEGFR2 (unknown origin) at IC50 in presence of ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248491
(2-(1-(3-Chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(py...)Show InChI InChI=1S/C20H16ClN5/c21-16-4-3-5-17(12-16)26-14-20(24-25-26)18-6-1-2-7-19(18)23-13-15-8-10-22-11-9-15/h1-12,14,23H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Binding affinity to VEGFR2 (unknown origin) at IC90 in presence of ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248491
(2-(1-(3-Chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(py...)Show InChI InChI=1S/C20H16ClN5/c21-16-4-3-5-17(12-16)26-14-20(24-25-26)18-6-1-2-7-19(18)23-13-15-8-10-22-11-9-15/h1-12,14,23H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Binding affinity to VEGFR2 (unknown origin) at IC50 in presence of ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248584
(2-(1-(3-isopropylphenyl)-1H-1,2,3-triazol-4-yl)-N-...)Show SMILES CC(C)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C23H23N5/c1-17(2)19-6-5-7-20(14-19)28-16-23(26-27-28)21-8-3-4-9-22(21)25-15-18-10-12-24-13-11-18/h3-14,16-17,25H,15H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Binding affinity to VEGFR2 (unknown origin) at IC90 in presence of ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248584
(2-(1-(3-isopropylphenyl)-1H-1,2,3-triazol-4-yl)-N-...)Show SMILES CC(C)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C23H23N5/c1-17(2)19-6-5-7-20(14-19)28-16-23(26-27-28)21-8-3-4-9-22(21)25-15-18-10-12-24-13-11-18/h3-14,16-17,25H,15H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Binding affinity to VEGFR2 (unknown origin) at IC50 in presence of ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM9503
(2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethy...)Show InChI InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA in presence of 8 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM4851
((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA in presence of 8 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM4851
((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM9503
(2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethy...)Show InChI InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 8 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM9503
(2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethy...)Show InChI InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM4851
((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 8 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248494
(CHEMBL490968 | N-(Pyridin-4-ylmethyl)-2-(1-(3-(tri...)Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H16F3N5/c22-21(23,24)16-4-3-5-17(12-16)29-14-20(27-28-29)18-6-1-2-7-19(18)26-13-15-8-10-25-11-9-15/h1-12,14,26H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM4851
((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248537
(CHEMBL491502 | N-(pyridin-4-ylmethyl)-2-(1-(3-(tri...)Show SMILES FC(F)(F)Oc1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H16F3N5O/c22-21(23,24)30-17-5-3-4-16(12-17)29-14-20(27-28-29)18-6-1-2-7-19(18)26-13-15-8-10-25-11-9-15/h1-12,14,26H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248494
(CHEMBL490968 | N-(Pyridin-4-ylmethyl)-2-(1-(3-(tri...)Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H16F3N5/c22-21(23,24)16-4-3-5-17(12-16)29-14-20(27-28-29)18-6-1-2-7-19(18)26-13-15-8-10-25-11-9-15/h1-12,14,26H,13H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248537
(CHEMBL491502 | N-(pyridin-4-ylmethyl)-2-(1-(3-(tri...)Show SMILES FC(F)(F)Oc1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H16F3N5O/c22-21(23,24)30-17-5-3-4-16(12-17)29-14-20(27-28-29)18-6-1-2-7-19(18)26-13-15-8-10-25-11-9-15/h1-12,14,26H,13H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248537
(CHEMBL491502 | N-(pyridin-4-ylmethyl)-2-(1-(3-(tri...)Show SMILES FC(F)(F)Oc1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H16F3N5O/c22-21(23,24)30-17-5-3-4-16(12-17)29-14-20(27-28-29)18-6-1-2-7-19(18)26-13-15-8-10-25-11-9-15/h1-12,14,26H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248491
(2-(1-(3-Chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(py...)Show InChI InChI=1S/C20H16ClN5/c21-16-4-3-5-17(12-16)26-14-20(24-25-26)18-6-1-2-7-19(18)23-13-15-8-10-22-11-9-15/h1-12,14,23H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM9503
(2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethy...)Show InChI InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248494
(CHEMBL490968 | N-(Pyridin-4-ylmethyl)-2-(1-(3-(tri...)Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H16F3N5/c22-21(23,24)16-4-3-5-17(12-16)29-14-20(27-28-29)18-6-1-2-7-19(18)26-13-15-8-10-25-11-9-15/h1-12,14,26H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 96 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM4851
((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay in presence of 8 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50247946
(2-(1-(4-methyl-3-(trifluoromethyl)phenyl)-1H-1,2,3...)Show SMILES Cc1ccc(cc1C(F)(F)F)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C22H18F3N5/c1-15-6-7-17(12-19(15)22(23,24)25)30-14-21(28-29-30)18-4-2-3-5-20(18)27-13-16-8-10-26-11-9-16/h2-12,14,27H,13H2,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248584
(2-(1-(3-isopropylphenyl)-1H-1,2,3-triazol-4-yl)-N-...)Show SMILES CC(C)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C23H23N5/c1-17(2)19-6-5-7-20(14-19)28-16-23(26-27-28)21-8-3-4-9-22(21)25-15-18-10-12-24-13-11-18/h3-14,16-17,25H,15H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248538
(2-(1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(py...)Show InChI InChI=1S/C20H16ClN5/c21-16-5-7-17(8-6-16)26-14-20(24-25-26)18-3-1-2-4-19(18)23-13-15-9-11-22-12-10-15/h1-12,14,23H,13H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248491
(2-(1-(3-Chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(py...)Show InChI InChI=1S/C20H16ClN5/c21-16-4-3-5-17(12-16)26-14-20(24-25-26)18-6-1-2-7-19(18)23-13-15-8-10-22-11-9-15/h1-12,14,23H,13H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM9503
(2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethy...)Show InChI InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay in presence of 8 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248584
(2-(1-(3-isopropylphenyl)-1H-1,2,3-triazol-4-yl)-N-...)Show SMILES CC(C)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C23H23N5/c1-17(2)19-6-5-7-20(14-19)28-16-23(26-27-28)21-8-3-4-9-22(21)25-15-18-10-12-24-13-11-18/h3-14,16-17,25H,15H2,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50247946
(2-(1-(4-methyl-3-(trifluoromethyl)phenyl)-1H-1,2,3...)Show SMILES Cc1ccc(cc1C(F)(F)F)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C22H18F3N5/c1-15-6-7-17(12-19(15)22(23,24)25)30-14-21(28-29-30)18-4-2-3-5-20(18)27-13-16-8-10-26-11-9-16/h2-12,14,27H,13H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM4851
((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248584
(2-(1-(3-isopropylphenyl)-1H-1,2,3-triazol-4-yl)-N-...)Show SMILES CC(C)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C23H23N5/c1-17(2)19-6-5-7-20(14-19)28-16-23(26-27-28)21-8-3-4-9-22(21)25-15-18-10-12-24-13-11-18/h3-14,16-17,25H,15H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248075
(CHEMBL517021 | N-(quinolin-4-ylmethyl)-2-(1-(3-(tr...)Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccnc2ccccc12 Show InChI InChI=1S/C25H18F3N5/c26-25(27,28)18-6-5-7-19(14-18)33-16-24(31-32-33)21-9-2-4-11-23(21)30-15-17-12-13-29-22-10-3-1-8-20(17)22/h1-14,16,30H,15H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248491
(2-(1-(3-Chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(py...)Show InChI InChI=1S/C20H16ClN5/c21-16-4-3-5-17(12-16)26-14-20(24-25-26)18-6-1-2-7-19(18)23-13-15-8-10-22-11-9-15/h1-12,14,23H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM9503
(2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethy...)Show InChI InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248033
((1-(3-Chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(quin...)Show SMILES Clc1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccnc2ccccc12 Show InChI InChI=1S/C24H18ClN5/c25-18-6-5-7-19(14-18)30-16-24(28-29-30)21-9-2-4-11-23(21)27-15-17-12-13-26-22-10-3-1-8-20(17)22/h1-14,16,27H,15H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50247946
(2-(1-(4-methyl-3-(trifluoromethyl)phenyl)-1H-1,2,3...)Show SMILES Cc1ccc(cc1C(F)(F)F)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C22H18F3N5/c1-15-6-7-17(12-19(15)22(23,24)25)30-14-21(28-29-30)18-4-2-3-5-20(18)27-13-16-8-10-26-11-9-16/h2-12,14,27H,13H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248033
((1-(3-Chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(quin...)Show SMILES Clc1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccnc2ccccc12 Show InChI InChI=1S/C24H18ClN5/c25-18-6-5-7-19(14-18)30-16-24(28-29-30)21-9-2-4-11-23(21)27-15-17-12-13-26-22-10-3-1-8-20(17)22/h1-14,16,27H,15H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248075
(CHEMBL517021 | N-(quinolin-4-ylmethyl)-2-(1-(3-(tr...)Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccnc2ccccc12 Show InChI InChI=1S/C25H18F3N5/c26-25(27,28)18-6-5-7-19(14-18)33-16-24(31-32-33)21-9-2-4-11-23(21)30-15-17-12-13-29-22-10-3-1-8-20(17)22/h1-14,16,30H,15H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248585
(2-(1-(3-tert-butylphenyl)-1H-1,2,3-triazol-4-yl)-N...)Show SMILES CC(C)(C)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C24H25N5/c1-24(2,3)19-7-6-8-20(15-19)29-17-23(27-28-29)21-9-4-5-10-22(21)26-16-18-11-13-25-14-12-18/h4-15,17,26H,16H2,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248585
(2-(1-(3-tert-butylphenyl)-1H-1,2,3-triazol-4-yl)-N...)Show SMILES CC(C)(C)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C24H25N5/c1-24(2,3)19-7-6-8-20(15-19)29-17-23(27-28-29)21-9-4-5-10-22(21)26-16-18-11-13-25-14-12-18/h4-15,17,26H,16H2,1-3H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248538
(2-(1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(py...)Show InChI InChI=1S/C20H16ClN5/c21-16-5-7-17(8-6-16)26-14-20(24-25-26)18-3-1-2-4-19(18)23-13-15-9-11-22-12-10-15/h1-12,14,23H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248033
((1-(3-Chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(quin...)Show SMILES Clc1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccnc2ccccc12 Show InChI InChI=1S/C24H18ClN5/c25-18-6-5-7-19(14-18)30-16-24(28-29-30)21-9-2-4-11-23(21)27-15-17-12-13-26-22-10-3-1-8-20(17)22/h1-14,16,27H,15H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248075
(CHEMBL517021 | N-(quinolin-4-ylmethyl)-2-(1-(3-(tr...)Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccnc2ccccc12 Show InChI InChI=1S/C25H18F3N5/c26-25(27,28)18-6-5-7-19(14-18)33-16-24(31-32-33)21-9-2-4-11-23(21)30-15-17-12-13-29-22-10-3-1-8-20(17)22/h1-14,16,30H,15H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248585
(2-(1-(3-tert-butylphenyl)-1H-1,2,3-triazol-4-yl)-N...)Show SMILES CC(C)(C)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C24H25N5/c1-24(2,3)19-7-6-8-20(15-19)29-17-23(27-28-29)21-9-4-5-10-22(21)26-16-18-11-13-25-14-12-18/h4-15,17,26H,16H2,1-3H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248538
(2-(1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(py...)Show InChI InChI=1S/C20H16ClN5/c21-16-5-7-17(8-6-16)26-14-20(24-25-26)18-3-1-2-4-19(18)23-13-15-9-11-22-12-10-15/h1-12,14,23H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 390 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50247943
(2-(1-(4-chloro-3-(trifluoromethyl)phenyl)-1H-1,2,3...)Show SMILES FC(F)(F)c1cc(ccc1Cl)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H15ClF3N5/c22-18-6-5-15(11-17(18)21(23,24)25)30-13-20(28-29-30)16-3-1-2-4-19(16)27-12-14-7-9-26-10-8-14/h1-11,13,27H,12H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50247943
(2-(1-(4-chloro-3-(trifluoromethyl)phenyl)-1H-1,2,3...)Show SMILES FC(F)(F)c1cc(ccc1Cl)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H15ClF3N5/c22-18-6-5-15(11-17(18)21(23,24)25)30-13-20(28-29-30)16-3-1-2-4-19(16)27-12-14-7-9-26-10-8-14/h1-11,13,27H,12H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 510 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248586
(2-(1-(4-tert-butylphenyl)-1H-1,2,3-triazol-4-yl)-N...)Show SMILES CC(C)(C)c1ccc(cc1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C24H25N5/c1-24(2,3)19-8-10-20(11-9-19)29-17-23(27-28-29)21-6-4-5-7-22(21)26-16-18-12-14-25-15-13-18/h4-15,17,26H,16H2,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 530 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248539
(CHEMBL522304 | N-(pyridin-4-ylmethyl)-2-(1-(4-(tri...)Show SMILES FC(F)(F)c1ccc(cc1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H16F3N5/c22-21(23,24)16-5-7-17(8-6-16)29-14-20(27-28-29)18-3-1-2-4-19(18)26-13-15-9-11-25-12-10-15/h1-12,14,26H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248586
(2-(1-(4-tert-butylphenyl)-1H-1,2,3-triazol-4-yl)-N...)Show SMILES CC(C)(C)c1ccc(cc1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C24H25N5/c1-24(2,3)19-8-10-20(11-9-19)29-17-23(27-28-29)21-6-4-5-7-22(21)26-16-18-12-14-25-15-13-18/h4-15,17,26H,16H2,1-3H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 610 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |