Found 31 hits Enz. Inhib. hit(s) with all data for entry = 50029518 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Type-1 angiotensin II receptor B
(RAT) | BDBM50285171
(2-{2,6-Dioxo-4-propyl-3-[2'-(1H-tetrazol-5-yl)-bip...)Show SMILES CCCc1cc(=O)n(CC(=O)N(C)C)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C25H27N7O3/c1-4-7-19-14-22(33)32(16-23(34)30(2)3)25(35)31(19)15-17-10-12-18(13-11-17)20-8-5-6-9-21(20)24-26-28-29-27-24/h5-6,8-14H,4,7,15-16H2,1-3H3,(H,26,27,28,29) | PDB
Reactome pathway
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PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 0.650 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in rat adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor B
(RAT) | BDBM50285164
(1-Cyclohexyl-3-(2-{2,6-dioxo-4-propyl-3-[2'-(1H-te...)Show SMILES CCCc1cc(=O)n(CCNC(=O)NC2CCCCC2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C30H36N8O3/c1-2-8-24-19-27(39)37(18-17-31-29(40)32-23-9-4-3-5-10-23)30(41)38(24)20-21-13-15-22(16-14-21)25-11-6-7-12-26(25)28-33-35-36-34-28/h6-7,11-16,19,23H,2-5,8-10,17-18,20H2,1H3,(H2,31,32,40)(H,33,34,35,36) | PDB
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| n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in rat adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor B
(RAT) | BDBM50285165
(2-{2,6-Dioxo-4-propyl-3-[2'-(1H-tetrazol-5-yl)-bip...)Show SMILES CCCc1cc(=O)n(Cc2ccccc2C(=O)OC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C30H28N6O4/c1-3-8-23-17-27(37)36(19-22-9-4-5-11-25(22)29(38)40-2)30(39)35(23)18-20-13-15-21(16-14-20)24-10-6-7-12-26(24)28-31-33-34-32-28/h4-7,9-17H,3,8,18-19H2,1-2H3,(H,31,32,33,34) | PDB
Reactome pathway
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PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in rat adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor B
(RAT) | BDBM50285163
(2-{4-Butyl-2,6-dioxo-3-[2'-(1H-tetrazol-5-yl)-biph...)Show SMILES CCCCc1cc(=O)n(Cc2ccccc2C(=O)OC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C31H30N6O4/c1-3-4-10-24-18-28(38)37(20-23-9-5-6-12-26(23)30(39)41-2)31(40)36(24)19-21-14-16-22(17-15-21)25-11-7-8-13-27(25)29-32-34-35-33-29/h5-9,11-18H,3-4,10,19-20H2,1-2H3,(H,32,33,34,35) | PDB
Reactome pathway
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PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in rat adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor B
(RAT) | BDBM50285166
(3-Allyl-6-propyl-1-[2'-(1H-tetrazol-5-yl)-biphenyl...)Show SMILES CCCc1cc(=O)n(CC=C)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C24H24N6O2/c1-3-7-19-15-22(31)29(14-4-2)24(32)30(19)16-17-10-12-18(13-11-17)20-8-5-6-9-21(20)23-25-27-28-26-23/h4-6,8-13,15H,2-3,7,14,16H2,1H3,(H,25,26,27,28) | PDB
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PC cid
PC sid
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Similars
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| n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in rat adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor B
(RAT) | BDBM50285160
(CHEMBL292781 | N-(2-{2,6-Dioxo-4-propyl-3-[2'-(1H-...)Show SMILES CCCc1cc(=O)n(CCNC(C)=O)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C25H27N7O3/c1-3-6-20-15-23(34)31(14-13-26-17(2)33)25(35)32(20)16-18-9-11-19(12-10-18)21-7-4-5-8-22(21)24-27-29-30-28-24/h4-5,7-12,15H,3,6,13-14,16H2,1-2H3,(H,26,33)(H,27,28,29,30) | PDB
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PC cid
PC sid
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Similars
| Article
| n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in rat adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor B
(RAT) | BDBM50285177
(6-Propyl-1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)Show SMILES CCCc1cc(=O)[nH]c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C21H20N6O2/c1-2-5-16-12-19(28)22-21(29)27(16)13-14-8-10-15(11-9-14)17-6-3-4-7-18(17)20-23-25-26-24-20/h3-4,6-12H,2,5,13H2,1H3,(H,22,28,29)(H,23,24,25,26) | PDB
Reactome pathway
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PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in rat adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50285173
(2-(2-{2,6-Dioxo-4-propyl-3-[2'-(1H-tetrazol-5-yl)-...)Show SMILES CCCc1cc(=O)n(CCN2C(=O)c3ccccc3C2=O)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C31H27N7O4/c1-2-7-22-18-27(39)36(16-17-37-29(40)25-10-5-6-11-26(25)30(37)41)31(42)38(22)19-20-12-14-21(15-13-20)23-8-3-4-9-24(23)28-32-34-35-33-28/h3-6,8-15,18H,2,7,16-17,19H2,1H3,(H,32,33,34,35) | PDB
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PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in rat adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor B
(RAT) | BDBM50285167
(6-Butyl-3-methyl-1-[2'-(1H-tetrazol-5-yl)-biphenyl...)Show SMILES CCCCc1cc(=O)n(C)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C23H24N6O2/c1-3-4-7-18-14-21(30)28(2)23(31)29(18)15-16-10-12-17(13-11-16)19-8-5-6-9-20(19)22-24-26-27-25-22/h5-6,8-14H,3-4,7,15H2,1-2H3,(H,24,25,26,27) | PDB
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PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in rat adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor B
(RAT) | BDBM50285175
(7-Propyl-6-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)Show SMILES CCCc1cc2ncnn2c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C22H20N8O/c1-2-5-17-12-20-23-14-24-30(20)22(31)29(17)13-15-8-10-16(11-9-15)18-6-3-4-7-19(18)21-25-27-28-26-21/h3-4,6-12,14H,2,5,13H2,1H3,(H,25,26,27,28) | PDB
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| Article
| n/a | n/a | 6.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in rat adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor B
(RAT) | BDBM50009714
(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)Show SMILES CCCCC1=NC(Cl)C(CO)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 |t:4| Show InChI InChI=1S/C22H25ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7,9-12,19,21,30H,2-3,8,13-14H2,1H3,(H,25,26,27,28) | PDB
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| n/a | n/a | 8.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in rat adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50285171
(2-{2,6-Dioxo-4-propyl-3-[2'-(1H-tetrazol-5-yl)-bip...)Show SMILES CCCc1cc(=O)n(CC(=O)N(C)C)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C25H27N7O3/c1-4-7-19-14-22(33)32(16-23(34)30(2)3)25(35)31(19)15-17-10-12-18(13-11-17)20-8-5-6-9-21(20)24-26-28-29-27-24/h5-6,8-14H,4,7,15-16H2,1-3H3,(H,26,27,28,29) | PDB
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PC cid
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| Article
| n/a | n/a | 9.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in bovine adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50285170
(CHEMBL62314 | N-(2-{2,6-Dioxo-4-propyl-3-[2'-(1H-t...)Show SMILES CCCc1cc(=O)n(CCNC(=O)C(c2ccccc2)c2ccccc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C37H35N7O3/c1-2-11-30-24-33(45)43(23-22-38-36(46)34(28-12-5-3-6-13-28)29-14-7-4-8-15-29)37(47)44(30)25-26-18-20-27(21-19-26)31-16-9-10-17-32(31)35-39-41-42-40-35/h3-10,12-21,24,34H,2,11,22-23,25H2,1H3,(H,38,46)(H,39,40,41,42) | PDB
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| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in rat adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50285172
(3-Butyl-6-propyl-1-[2'-(1H-tetrazol-5-yl)-biphenyl...)Show SMILES CCCCn1c(=O)cc(CCC)n(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)c1=O Show InChI InChI=1S/C25H28N6O2/c1-3-5-15-30-23(32)16-20(8-4-2)31(25(30)33)17-18-11-13-19(14-12-18)21-9-6-7-10-22(21)24-26-28-29-27-24/h6-7,9-14,16H,3-5,8,15,17H2,1-2H3,(H,26,27,28,29) | PDB
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| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in bovine adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor B
(RAT) | BDBM50285161
(3-Methyl-6-propyl-1-[2'-(1H-tetrazol-5-yl)-bipheny...)Show SMILES CCCc1cc(=O)n(C)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C22H22N6O2/c1-3-6-17-13-20(29)27(2)22(30)28(17)14-15-9-11-16(12-10-15)18-7-4-5-8-19(18)21-23-25-26-24-21/h4-5,7-13H,3,6,14H2,1-2H3,(H,23,24,25,26) | PDB
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| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in rat adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50285165
(2-{2,6-Dioxo-4-propyl-3-[2'-(1H-tetrazol-5-yl)-bip...)Show SMILES CCCc1cc(=O)n(Cc2ccccc2C(=O)OC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C30H28N6O4/c1-3-8-23-17-27(37)36(19-22-9-4-5-11-25(22)29(38)40-2)30(39)35(23)18-20-13-15-21(16-14-20)24-10-6-7-12-26(24)28-31-33-34-32-28/h4-7,9-17H,3,8,18-19H2,1-2H3,(H,31,32,33,34) | PDB
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| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in bovine adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50285164
(1-Cyclohexyl-3-(2-{2,6-dioxo-4-propyl-3-[2'-(1H-te...)Show SMILES CCCc1cc(=O)n(CCNC(=O)NC2CCCCC2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C30H36N8O3/c1-2-8-24-19-27(39)37(18-17-31-29(40)32-23-9-4-3-5-10-23)30(41)38(24)20-21-13-15-22(16-14-21)25-11-6-7-12-26(25)28-33-35-36-34-28/h6-7,11-16,19,23H,2-5,8-10,17-18,20H2,1H3,(H2,31,32,40)(H,33,34,35,36) | PDB
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| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in bovine adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50285168
(3-Benzyl-6-propyl-1-[2'-(1H-tetrazol-5-yl)-bipheny...)Show SMILES CCCc1cc(=O)n(Cc2ccccc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C28H26N6O2/c1-2-8-23-17-26(35)34(19-20-9-4-3-5-10-20)28(36)33(23)18-21-13-15-22(16-14-21)24-11-6-7-12-25(24)27-29-31-32-30-27/h3-7,9-17H,2,8,18-19H2,1H3,(H,29,30,31,32) | PDB
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| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in bovine adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50285163
(2-{4-Butyl-2,6-dioxo-3-[2'-(1H-tetrazol-5-yl)-biph...)Show SMILES CCCCc1cc(=O)n(Cc2ccccc2C(=O)OC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C31H30N6O4/c1-3-4-10-24-18-28(38)37(20-23-9-5-6-12-26(23)30(39)41-2)31(40)36(24)19-21-14-16-22(17-15-21)25-11-7-8-13-27(25)29-32-34-35-33-29/h5-9,11-18H,3-4,10,19-20H2,1-2H3,(H,32,33,34,35) | PDB
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| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in bovine adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50285166
(3-Allyl-6-propyl-1-[2'-(1H-tetrazol-5-yl)-biphenyl...)Show SMILES CCCc1cc(=O)n(CC=C)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C24H24N6O2/c1-3-7-19-15-22(31)29(14-4-2)24(32)30(19)16-17-10-12-18(13-11-17)20-8-5-6-9-21(20)23-25-27-28-26-23/h4-6,8-13,15H,2-3,7,14,16H2,1H3,(H,25,26,27,28) | PDB
Reactome pathway
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| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in bovine adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50285160
(CHEMBL292781 | N-(2-{2,6-Dioxo-4-propyl-3-[2'-(1H-...)Show SMILES CCCc1cc(=O)n(CCNC(C)=O)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C25H27N7O3/c1-3-6-20-15-23(34)31(14-13-26-17(2)33)25(35)32(20)16-18-9-11-19(12-10-18)21-7-4-5-8-22(21)24-27-29-30-28-24/h4-5,7-12,15H,3,6,13-14,16H2,1-2H3,(H,26,33)(H,27,28,29,30) | PDB
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| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in bovine adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50285167
(6-Butyl-3-methyl-1-[2'-(1H-tetrazol-5-yl)-biphenyl...)Show SMILES CCCCc1cc(=O)n(C)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C23H24N6O2/c1-3-4-7-18-14-21(30)28(2)23(31)29(18)15-16-10-12-17(13-11-16)19-8-5-6-9-20(19)22-24-26-27-25-22/h5-6,8-14H,3-4,7,15H2,1-2H3,(H,24,25,26,27) | PDB
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| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in bovine adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50285161
(3-Methyl-6-propyl-1-[2'-(1H-tetrazol-5-yl)-bipheny...)Show SMILES CCCc1cc(=O)n(C)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C22H22N6O2/c1-3-6-17-13-20(29)27(2)22(30)28(17)14-15-9-11-16(12-10-15)18-7-4-5-8-19(18)21-23-25-26-24-21/h4-5,7-13H,3,6,14H2,1-2H3,(H,23,24,25,26) | PDB
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| n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in bovine adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50285175
(7-Propyl-6-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)Show SMILES CCCc1cc2ncnn2c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C22H20N8O/c1-2-5-17-12-20-23-14-24-30(20)22(31)29(17)13-15-8-10-16(11-9-15)18-6-3-4-7-19(18)21-25-27-28-26-21/h3-4,6-12,14H,2,5,13H2,1H3,(H,25,26,27,28) | PDB
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| n/a | n/a | 62 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in bovine adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor B
(RAT) | BDBM50285162
(5-Butyl-2-phenyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl...)Show SMILES CCCCc1cc(=O)n2nc(nc2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)-c1ccccc1 Show InChI InChI=1S/C29H26N8O/c1-2-3-11-23-18-26(38)37-29(30-27(33-37)22-9-5-4-6-10-22)36(23)19-20-14-16-21(17-15-20)24-12-7-8-13-25(24)28-31-34-35-32-28/h4-10,12-18H,2-3,11,19H2,1H3,(H,31,32,34,35) | PDB
Reactome pathway
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| n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in rat adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50285177
(6-Propyl-1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)Show SMILES CCCc1cc(=O)[nH]c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C21H20N6O2/c1-2-5-16-12-19(28)22-21(29)27(16)13-14-8-10-15(11-9-14)17-6-3-4-7-18(17)20-23-25-26-24-20/h3-4,6-12H,2,5,13H2,1H3,(H,22,28,29)(H,23,24,25,26) | PDB
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| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in bovine adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50009714
(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)Show SMILES CCCCC1=NC(Cl)C(CO)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 |t:4| Show InChI InChI=1S/C22H25ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7,9-12,19,21,30H,2-3,8,13-14H2,1H3,(H,25,26,27,28) | PDB
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| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in bovine adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50285162
(5-Butyl-2-phenyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl...)Show SMILES CCCCc1cc(=O)n2nc(nc2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)-c1ccccc1 Show InChI InChI=1S/C29H26N8O/c1-2-3-11-23-18-26(38)37-29(30-27(33-37)22-9-5-4-6-10-22)36(23)19-20-14-16-21(17-15-20)24-12-7-8-13-25(24)28-31-34-35-32-28/h4-10,12-18H,2-3,11,19H2,1H3,(H,31,32,34,35) | PDB
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| n/a | n/a | 520 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in bovine adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50285176
(6-Ethyl-3-methyl-1-[2'-(1H-tetrazol-5-yl)-biphenyl...)Show SMILES CCc1cc(=O)n(C)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C21H20N6O2/c1-3-16-12-19(28)26(2)21(29)27(16)13-14-8-10-15(11-9-14)17-6-4-5-7-18(17)20-22-24-25-23-20/h4-12H,3,13H2,1-2H3,(H,22,23,24,25) | PDB
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| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in bovine adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50285169
(6-Cyclopropyl-3-methyl-1-[2'-(1H-tetrazol-5-yl)-bi...)Show SMILES Cn1c(=O)cc(C2CC2)n(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)c1=O Show InChI InChI=1S/C22H20N6O2/c1-27-20(29)12-19(16-10-11-16)28(22(27)30)13-14-6-8-15(9-7-14)17-4-2-3-5-18(17)21-23-25-26-24-21/h2-9,12,16H,10-11,13H2,1H3,(H,23,24,25,26) | PDB
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| n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in bovine adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50285174
(3,5-Dimethyl-6-propyl-1-[2'-(1H-tetrazol-5-yl)-bip...)Show SMILES CCCc1c(C)c(=O)n(C)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C23H24N6O2/c1-4-7-20-15(2)22(30)28(3)23(31)29(20)14-16-10-12-17(13-11-16)18-8-5-6-9-19(18)21-24-26-27-25-21/h5-6,8-13H,4,7,14H2,1-3H3,(H,24,25,26,27) | PDB
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| n/a | n/a | 6.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for binding affinity against angiotensin II receptor in bovine adrenal cortex |
Bioorg Med Chem Lett 5: 2071-2076 (1995)
Article DOI: 10.1016/0960-894X(95)00370-9
BindingDB Entry DOI: 10.7270/Q2SF2W4J |
More data for this
Ligand-Target Pair | |
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