Compile Data Set for Download or QSAR

Found 80 hits Enz. Inhib. hit(s) with all data for entry = 50030237   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50292997 (2-Amino-4-(4-methoxyphenyl)-7-(naphthalene-1-yl)-5...) Show SMILES COc1ccc(cc1)C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1cccc2ccccc12 |c:16| Show InChI InChI=1S/C27H22N2O3/c1-31-19-11-9-17(10-12-19)25-22(15-28)27(29)32-24-14-18(13-23(30)26(24)25)21-8-4-6-16-5-2-3-7-20(16)21/h2-12,18,22,25,29H,13-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at human EAAT1 expressed in HEK293 cells assessed as inhibition of Glu-induced fluorescent response by FLIPR membrane potential blue assay				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50292997 (2-Amino-4-(4-methoxyphenyl)-7-(naphthalene-1-yl)-5...) Show SMILES COc1ccc(cc1)C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1cccc2ccccc12 |c:16| Show InChI InChI=1S/C27H22N2O3/c1-31-19-11-9-17(10-12-19)25-22(15-28)27(29)32-24-14-18(13-23(30)26(24)25)21-8-4-6-16-5-2-3-7-20(16)21/h2-12,18,22,25,29H,13-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Rattus norvegicus)	BDBM50292997 (2-Amino-4-(4-methoxyphenyl)-7-(naphthalene-1-yl)-5...) Show SMILES COc1ccc(cc1)C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1cccc2ccccc12 |c:16| Show InChI InChI=1S/C27H22N2O3/c1-31-19-11-9-17(10-12-19)25-22(15-28)27(29)32-24-14-18(13-23(30)26(24)25)21-8-4-6-16-5-2-3-7-20(16)21/h2-12,18,22,25,29H,13-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	970	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat EAAT1 expressed in TSA201 cells assessed as inhibition of Glu-induced fluorescent response by FLIPR membrane potential blue assay				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50293001 (2-amino-4-(biphenyl-4-yl)-5-oxo-7-phenyl-5,6,7,8-t...) Show SMILES N=C1OC2=C(C(C1C#N)c1ccc(cc1)-c1ccccc1)C(=O)CC(C2)c1ccccc1 |c:3| Show InChI InChI=1S/C28H22N2O2/c29-17-23-26(21-13-11-20(12-14-21)18-7-3-1-4-8-18)27-24(31)15-22(16-25(27)32-28(23)30)19-9-5-2-6-10-19/h1-14,22-23,26,30H,15-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50293009 (2-Amino-4-(4-methoxyphenyl)-7-(phenyl)-5-oxo-5,6,7...) Show SMILES COc1ccc(cc1)C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1ccccc1 |c:16| Show InChI InChI=1S/C23H20N2O3/c1-27-17-9-7-15(8-10-17)21-18(13-24)23(25)28-20-12-16(11-19(26)22(20)21)14-5-3-2-4-6-14/h2-10,16,18,21,25H,11-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50293010 (2-amino-4-(4-(methylthio)phenyl)-5-oxo-7-phenyl-5,...) Show SMILES CSc1ccc(cc1)C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1ccccc1 |c:16| Show InChI InChI=1S/C23H20N2O2S/c1-28-17-9-7-15(8-10-17)21-18(13-24)23(25)27-20-12-16(11-19(26)22(20)21)14-5-3-2-4-6-14/h2-10,16,18,21,25H,11-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50292999 (2-amino-7-(2-chlorophenyl)-4-(4-methoxyphenyl)-5-o...) Show SMILES COc1ccc(cc1)C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1ccccc1Cl |c:16| Show InChI InChI=1S/C23H19ClN2O3/c1-28-15-8-6-13(7-9-15)21-17(12-25)23(26)29-20-11-14(10-19(27)22(20)21)16-4-2-3-5-18(16)24/h2-9,14,17,21,26H,10-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50293008 (2-amino-4-(4-nitrophenyl)-5-oxo-7-phenyl-5,6,7,8-t...) Show SMILES [O-][N+](=O)c1ccc(cc1)C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1ccccc1 |c:17| Show InChI InChI=1S/C22H17N3O4/c23-12-17-20(14-6-8-16(9-7-14)25(27)28)21-18(26)10-15(11-19(21)29-22(17)24)13-4-2-1-3-5-13/h1-9,15,17,20,24H,10-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50293002 (2-amino-4-(naphthalen-2-yl)-5-oxo-7-phenyl-5,6,7,8...) Show SMILES N=C1OC2=C(C(C1C#N)c1ccc3ccccc3c1)C(=O)CC(C2)c1ccccc1 |c:3| Show InChI InChI=1S/C26H20N2O2/c27-15-21-24(19-11-10-17-8-4-5-9-18(17)12-19)25-22(29)13-20(14-23(25)30-26(21)28)16-6-2-1-3-7-16/h1-12,20-21,24,28H,13-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50293007 (2-amino-4-(benzo[d][1,3]dioxol-5-yl)-5-oxo-7-pheny...) Show SMILES N=C1OC2=C(C(C1C#N)c1ccc3OCOc3c1)C(=O)CC(C2)c1ccccc1 |c:3| Show InChI InChI=1S/C23H18N2O4/c24-11-16-21(14-6-7-18-19(9-14)28-12-27-18)22-17(26)8-15(10-20(22)29-23(16)25)13-4-2-1-3-5-13/h1-7,9,15-16,21,25H,8,10,12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50293000 (2-amino-4-(4-(2-chloro-6-fluorobenzyloxy)-3-methox...) Show SMILES COc1cc(ccc1OCc1c(F)cccc1Cl)C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1ccccc1 |c:27| Show InChI InChI=1S/C30H24ClFN2O4/c1-36-26-13-18(10-11-25(26)37-16-21-22(31)8-5-9-23(21)32)28-20(15-33)30(34)38-27-14-19(12-24(35)29(27)28)17-6-3-2-4-7-17/h2-11,13,19-20,28,34H,12,14,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50292986 (2-amino-4-(2-fluorophenyl)-5-oxo-7-phenyl-5,6,7,8-...) Show SMILES Fc1ccccc1C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1ccccc1 |c:15| Show InChI InChI=1S/C22H17FN2O2/c23-17-9-5-4-8-15(17)20-16(12-24)22(25)27-19-11-14(10-18(26)21(19)20)13-6-2-1-3-7-13/h1-9,14,16,20,25H,10-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50293004 (2-amino-4-(4-bromothiophen-2-yl)-5-oxo-7-phenyl-5,...) Show SMILES Brc1csc(c1)C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1ccccc1 |c:14| Show InChI InChI=1S/C20H15BrN2O2S/c21-13-8-17(26-10-13)18-14(9-22)20(23)25-16-7-12(6-15(24)19(16)18)11-4-2-1-3-5-11/h1-5,8,10,12,14,18,23H,6-7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50292996 (2-amino-7-(furan-2-yl)-5-oxo-4-phenyl-5,6,7,8-tetr...) Show SMILES N=C1OC2=C(C(C1C#N)c1ccccc1)C(=O)CC(C2)c1ccco1 |c:3| Show InChI InChI=1S/C20H16N2O3/c21-11-14-18(12-5-2-1-3-6-12)19-15(23)9-13(16-7-4-8-24-16)10-17(19)25-20(14)22/h1-8,13-14,18,22H,9-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50293003 (2-amino-4-(naphthalen-1-yl)-5-oxo-7-phenyl-5,6,7,8...) Show SMILES N=C1OC2=C(C(C1C#N)c1cccc3ccccc13)C(=O)CC(C2)c1ccccc1 |c:3| Show InChI InChI=1S/C26H20N2O2/c27-15-21-24(20-12-6-10-17-9-4-5-11-19(17)20)25-22(29)13-18(14-23(25)30-26(21)28)16-7-2-1-3-8-16/h1-12,18,21,24,28H,13-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50292990 (2-amino-4-methyl-5-oxo-7-phenyl-5,6,7,8-tetrahydro...) Show SMILES CC1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1ccccc1 |c:8| Show InChI InChI=1S/C17H16N2O2/c1-10-13(9-18)17(19)21-15-8-12(7-14(20)16(10)15)11-5-3-2-4-6-11/h2-6,10,12-13,19H,7-8H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50292994 (2-amino-4-(4-nitrophenyl)-5-oxo-7-(thiophen-2-yl)-...) Show SMILES [O-][N+](=O)c1ccc(cc1)C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1cccs1 |c:17| Show InChI InChI=1S/C20H15N3O4S/c21-10-14-18(11-3-5-13(6-4-11)23(25)26)19-15(24)8-12(17-2-1-7-28-17)9-16(19)27-20(14)22/h1-7,12,14,18,22H,8-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50292998 (2-Amino-4-(4-methoxyphenyl)-7-(3,4-dimethoxyphenyl...) Show SMILES COc1ccc(cc1)C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1ccc(OC)c(OC)c1 |c:16| Show InChI InChI=1S/C25H24N2O5/c1-29-17-7-4-14(5-8-17)23-18(13-26)25(27)32-22-12-16(10-19(28)24(22)23)15-6-9-20(30-2)21(11-15)31-3/h4-9,11,16,18,23,27H,10,12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50293005 (2-amino-5-oxo-7-phenyl-4-(thiophen-2-yl)-5,6,7,8-t...) Show SMILES N=C1OC2=C(C(C1C#N)c1cccs1)C(=O)CC(C2)c1ccccc1 |c:3| Show InChI InChI=1S/C20H16N2O2S/c21-11-14-18(17-7-4-8-25-17)19-15(23)9-13(10-16(19)24-20(14)22)12-5-2-1-3-6-12/h1-8,13-14,18,22H,9-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50292991 (2-amino-4-benzyl-5-oxo-7-phenyl-5,6,7,8-tetrahydro...) Show SMILES N=C1OC2=C(C(Cc3ccccc3)C1C#N)C(=O)CC(C2)c1ccccc1 |c:3| Show InChI InChI=1S/C23H20N2O2/c24-14-19-18(11-15-7-3-1-4-8-15)22-20(26)12-17(13-21(22)27-23(19)25)16-9-5-2-6-10-16/h1-10,17-19,25H,11-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50292993 (2-amino-5-oxo-7-phenyl-4-(pyridin-3-yl)-5,6,7,8-te...) Show SMILES N=C1OC2=C(C(C1C#N)c1cccnc1)C(=O)CC(C2)c1ccccc1 |c:3| Show InChI InChI=1S/C21H17N3O2/c22-11-16-19(14-7-4-8-24-12-14)20-17(25)9-15(10-18(20)26-21(16)23)13-5-2-1-3-6-13/h1-8,12,15-16,19,23H,9-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50293006 (2-amino-4-(2,3-dimethoxyphenyl)-5-oxo-7-phenyl-5,6...) Show SMILES COc1cccc(C2C(C#N)C(=N)OC3=C2C(=O)CC(C3)c2ccccc2)c1OC |c:14| Show InChI InChI=1S/C24H22N2O4/c1-28-19-10-6-9-16(23(19)29-2)21-17(13-25)24(26)30-20-12-15(11-18(27)22(20)21)14-7-4-3-5-8-14/h3-10,15,17,21,26H,11-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50292986 (2-amino-4-(2-fluorophenyl)-5-oxo-7-phenyl-5,6,7,8-...) Show SMILES Fc1ccccc1C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1ccccc1 |c:15| Show InChI InChI=1S/C22H17FN2O2/c23-17-9-5-4-8-15(17)20-16(12-24)22(25)27-19-11-14(10-18(26)21(19)20)13-6-2-1-3-7-13/h1-9,14,16,20,25H,10-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT2 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 3 (Homo sapiens (Human))	BDBM50292986 (2-amino-4-(2-fluorophenyl)-5-oxo-7-phenyl-5,6,7,8-...) Show SMILES Fc1ccccc1C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1ccccc1 |c:15| Show InChI InChI=1S/C22H17FN2O2/c23-17-9-5-4-8-15(17)20-16(12-24)22(25)27-19-11-14(10-18(26)21(19)20)13-6-2-1-3-7-13/h1-9,14,16,20,25H,10-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT3 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50292992 (2-amino-4-(1H-indol-3-yl)-5-oxo-7-phenyl-5,6,7,8-t...) Show SMILES N=C1OC2=C(C(C1C#N)c1c[nH]c3ccccc13)C(=O)CC(C2)c1ccccc1 |c:3| Show InChI InChI=1S/C24H19N3O2/c25-12-17-22(18-13-27-19-9-5-4-8-16(18)19)23-20(28)10-15(11-21(23)29-24(17)26)14-6-2-1-3-7-14/h1-9,13,15,17,22,26-27H,10-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50292995 (5-(2-amino-3-cyano-7-(furan-2-yl)-5-oxo-5,6,7,8-te...) Show SMILES COc1ccc(cc1OC(=O)N1CCOCC1)C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1ccco1 |c:26| Show InChI InChI=1S/C26H25N3O7/c1-32-20-5-4-15(12-21(20)36-26(31)29-6-9-33-10-7-29)23-17(14-27)25(28)35-22-13-16(11-18(30)24(22)23)19-3-2-8-34-19/h2-5,8,12,16-17,23,28H,6-7,9-11,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50292991 (2-amino-4-benzyl-5-oxo-7-phenyl-5,6,7,8-tetrahydro...) Show SMILES N=C1OC2=C(C(Cc3ccccc3)C1C#N)C(=O)CC(C2)c1ccccc1 |c:3| Show InChI InChI=1S/C23H20N2O2/c24-14-19-18(11-15-7-3-1-4-8-15)22-20(26)12-17(13-21(22)27-23(19)25)16-9-5-2-6-10-16/h1-10,17-19,25H,11-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT2 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50292992 (2-amino-4-(1H-indol-3-yl)-5-oxo-7-phenyl-5,6,7,8-t...) Show SMILES N=C1OC2=C(C(C1C#N)c1c[nH]c3ccccc13)C(=O)CC(C2)c1ccccc1 |c:3| Show InChI InChI=1S/C24H19N3O2/c25-12-17-22(18-13-27-19-9-5-4-8-16(18)19)23-20(28)10-15(11-21(23)29-24(17)26)14-6-2-1-3-7-14/h1-9,13,15,17,22,26-27H,10-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT2 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50293000 (2-amino-4-(4-(2-chloro-6-fluorobenzyloxy)-3-methox...) Show SMILES COc1cc(ccc1OCc1c(F)cccc1Cl)C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1ccccc1 |c:27| Show InChI InChI=1S/C30H24ClFN2O4/c1-36-26-13-18(10-11-25(26)37-16-21-22(31)8-5-9-23(21)32)28-20(15-33)30(34)38-27-14-19(12-24(35)29(27)28)17-6-3-2-4-7-17/h2-11,13,19-20,28,34H,12,14,16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT2 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50293001 (2-amino-4-(biphenyl-4-yl)-5-oxo-7-phenyl-5,6,7,8-t...) Show SMILES N=C1OC2=C(C(C1C#N)c1ccc(cc1)-c1ccccc1)C(=O)CC(C2)c1ccccc1 |c:3| Show InChI InChI=1S/C28H22N2O2/c29-17-23-26(21-13-11-20(12-14-21)18-7-3-1-4-8-18)27-24(31)15-22(16-25(27)32-28(23)30)19-9-5-2-6-10-19/h1-14,22-23,26,30H,15-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT2 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50293002 (2-amino-4-(naphthalen-2-yl)-5-oxo-7-phenyl-5,6,7,8...) Show SMILES N=C1OC2=C(C(C1C#N)c1ccc3ccccc3c1)C(=O)CC(C2)c1ccccc1 |c:3| Show InChI InChI=1S/C26H20N2O2/c27-15-21-24(19-11-10-17-8-4-5-9-18(17)12-19)25-22(29)13-20(14-23(25)30-26(21)28)16-6-2-1-3-7-16/h1-12,20-21,24,28H,13-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT2 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50293003 (2-amino-4-(naphthalen-1-yl)-5-oxo-7-phenyl-5,6,7,8...) Show SMILES N=C1OC2=C(C(C1C#N)c1cccc3ccccc13)C(=O)CC(C2)c1ccccc1 |c:3| Show InChI InChI=1S/C26H20N2O2/c27-15-21-24(20-12-6-10-17-9-4-5-11-19(17)20)25-22(29)13-18(14-23(25)30-26(21)28)16-7-2-1-3-8-16/h1-12,18,21,24,28H,13-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT2 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50293004 (2-amino-4-(4-bromothiophen-2-yl)-5-oxo-7-phenyl-5,...) Show SMILES Brc1csc(c1)C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1ccccc1 |c:14| Show InChI InChI=1S/C20H15BrN2O2S/c21-13-8-17(26-10-13)18-14(9-22)20(23)25-16-7-12(6-15(24)19(16)18)11-4-2-1-3-5-11/h1-5,8,10,12,14,18,23H,6-7H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT2 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50293005 (2-amino-5-oxo-7-phenyl-4-(thiophen-2-yl)-5,6,7,8-t...) Show SMILES N=C1OC2=C(C(C1C#N)c1cccs1)C(=O)CC(C2)c1ccccc1 |c:3| Show InChI InChI=1S/C20H16N2O2S/c21-11-14-18(17-7-4-8-25-17)19-15(23)9-13(10-16(19)24-20(14)22)12-5-2-1-3-6-12/h1-8,13-14,18,22H,9-10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT2 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50293006 (2-amino-4-(2,3-dimethoxyphenyl)-5-oxo-7-phenyl-5,6...) Show SMILES COc1cccc(C2C(C#N)C(=N)OC3=C2C(=O)CC(C3)c2ccccc2)c1OC |c:14| Show InChI InChI=1S/C24H22N2O4/c1-28-19-10-6-9-16(23(19)29-2)21-17(13-25)24(26)30-20-12-15(11-18(27)22(20)21)14-7-4-3-5-8-14/h3-10,15,17,21,26H,11-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT2 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50293008 (2-amino-4-(4-nitrophenyl)-5-oxo-7-phenyl-5,6,7,8-t...) Show SMILES [O-][N+](=O)c1ccc(cc1)C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1ccccc1 |c:17| Show InChI InChI=1S/C22H17N3O4/c23-12-17-20(14-6-8-16(9-7-14)25(27)28)21-18(26)10-15(11-19(21)29-22(17)24)13-4-2-1-3-5-13/h1-9,15,17,20,24H,10-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT2 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50293009 (2-Amino-4-(4-methoxyphenyl)-7-(phenyl)-5-oxo-5,6,7...) Show SMILES COc1ccc(cc1)C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1ccccc1 |c:16| Show InChI InChI=1S/C23H20N2O3/c1-27-17-9-7-15(8-10-17)21-18(13-24)23(25)28-20-12-16(11-19(26)22(20)21)14-5-3-2-4-6-14/h2-10,16,18,21,25H,11-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT2 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50293010 (2-amino-4-(4-(methylthio)phenyl)-5-oxo-7-phenyl-5,...) Show SMILES CSc1ccc(cc1)C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1ccccc1 |c:16| Show InChI InChI=1S/C23H20N2O2S/c1-28-17-9-7-15(8-10-17)21-18(13-24)23(25)27-20-12-16(11-19(26)22(20)21)14-5-3-2-4-6-14/h2-10,16,18,21,25H,11-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT2 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 3 (Homo sapiens (Human))	BDBM50292991 (2-amino-4-benzyl-5-oxo-7-phenyl-5,6,7,8-tetrahydro...) Show SMILES N=C1OC2=C(C(Cc3ccccc3)C1C#N)C(=O)CC(C2)c1ccccc1 |c:3| Show InChI InChI=1S/C23H20N2O2/c24-14-19-18(11-15-7-3-1-4-8-15)22-20(26)12-17(13-21(22)27-23(19)25)16-9-5-2-6-10-16/h1-10,17-19,25H,11-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT3 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 3 (Homo sapiens (Human))	BDBM50292992 (2-amino-4-(1H-indol-3-yl)-5-oxo-7-phenyl-5,6,7,8-t...) Show SMILES N=C1OC2=C(C(C1C#N)c1c[nH]c3ccccc13)C(=O)CC(C2)c1ccccc1 |c:3| Show InChI InChI=1S/C24H19N3O2/c25-12-17-22(18-13-27-19-9-5-4-8-16(18)19)23-20(28)10-15(11-21(23)29-24(17)26)14-6-2-1-3-7-14/h1-9,13,15,17,22,26-27H,10-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT3 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 3 (Homo sapiens (Human))	BDBM50293000 (2-amino-4-(4-(2-chloro-6-fluorobenzyloxy)-3-methox...) Show SMILES COc1cc(ccc1OCc1c(F)cccc1Cl)C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1ccccc1 |c:27| Show InChI InChI=1S/C30H24ClFN2O4/c1-36-26-13-18(10-11-25(26)37-16-21-22(31)8-5-9-23(21)32)28-20(15-33)30(34)38-27-14-19(12-24(35)29(27)28)17-6-3-2-4-7-17/h2-11,13,19-20,28,34H,12,14,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT3 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 3 (Homo sapiens (Human))	BDBM50293001 (2-amino-4-(biphenyl-4-yl)-5-oxo-7-phenyl-5,6,7,8-t...) Show SMILES N=C1OC2=C(C(C1C#N)c1ccc(cc1)-c1ccccc1)C(=O)CC(C2)c1ccccc1 |c:3| Show InChI InChI=1S/C28H22N2O2/c29-17-23-26(21-13-11-20(12-14-21)18-7-3-1-4-8-18)27-24(31)15-22(16-25(27)32-28(23)30)19-9-5-2-6-10-19/h1-14,22-23,26,30H,15-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT3 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 3 (Homo sapiens (Human))	BDBM50293002 (2-amino-4-(naphthalen-2-yl)-5-oxo-7-phenyl-5,6,7,8...) Show SMILES N=C1OC2=C(C(C1C#N)c1ccc3ccccc3c1)C(=O)CC(C2)c1ccccc1 |c:3| Show InChI InChI=1S/C26H20N2O2/c27-15-21-24(19-11-10-17-8-4-5-9-18(17)12-19)25-22(29)13-20(14-23(25)30-26(21)28)16-6-2-1-3-7-16/h1-12,20-21,24,28H,13-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT3 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 3 (Homo sapiens (Human))	BDBM50293003 (2-amino-4-(naphthalen-1-yl)-5-oxo-7-phenyl-5,6,7,8...) Show SMILES N=C1OC2=C(C(C1C#N)c1cccc3ccccc13)C(=O)CC(C2)c1ccccc1 |c:3| Show InChI InChI=1S/C26H20N2O2/c27-15-21-24(20-12-6-10-17-9-4-5-11-19(17)20)25-22(29)13-18(14-23(25)30-26(21)28)16-7-2-1-3-8-16/h1-12,18,21,24,28H,13-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT3 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 3 (Homo sapiens (Human))	BDBM50293004 (2-amino-4-(4-bromothiophen-2-yl)-5-oxo-7-phenyl-5,...) Show SMILES Brc1csc(c1)C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1ccccc1 |c:14| Show InChI InChI=1S/C20H15BrN2O2S/c21-13-8-17(26-10-13)18-14(9-22)20(23)25-16-7-12(6-15(24)19(16)18)11-4-2-1-3-5-11/h1-5,8,10,12,14,18,23H,6-7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT3 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 3 (Homo sapiens (Human))	BDBM50293005 (2-amino-5-oxo-7-phenyl-4-(thiophen-2-yl)-5,6,7,8-t...) Show SMILES N=C1OC2=C(C(C1C#N)c1cccs1)C(=O)CC(C2)c1ccccc1 |c:3| Show InChI InChI=1S/C20H16N2O2S/c21-11-14-18(17-7-4-8-25-17)19-15(23)9-13(10-16(19)24-20(14)22)12-5-2-1-3-6-12/h1-8,13-14,18,22H,9-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT3 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 3 (Homo sapiens (Human))	BDBM50293006 (2-amino-4-(2,3-dimethoxyphenyl)-5-oxo-7-phenyl-5,6...) Show SMILES COc1cccc(C2C(C#N)C(=N)OC3=C2C(=O)CC(C3)c2ccccc2)c1OC |c:14| Show InChI InChI=1S/C24H22N2O4/c1-28-19-10-6-9-16(23(19)29-2)21-17(13-25)24(26)30-20-12-15(11-18(27)22(20)21)14-7-4-3-5-8-14/h3-10,15,17,21,26H,11-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT3 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 3 (Homo sapiens (Human))	BDBM50293008 (2-amino-4-(4-nitrophenyl)-5-oxo-7-phenyl-5,6,7,8-t...) Show SMILES [O-][N+](=O)c1ccc(cc1)C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1ccccc1 |c:17| Show InChI InChI=1S/C22H17N3O4/c23-12-17-20(14-6-8-16(9-7-14)25(27)28)21-18(26)10-15(11-19(21)29-22(17)24)13-4-2-1-3-5-13/h1-9,15,17,20,24H,10-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT3 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 3 (Homo sapiens (Human))	BDBM50293009 (2-Amino-4-(4-methoxyphenyl)-7-(phenyl)-5-oxo-5,6,7...) Show SMILES COc1ccc(cc1)C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1ccccc1 |c:16| Show InChI InChI=1S/C23H20N2O3/c1-27-17-9-7-15(8-10-17)21-18(13-24)23(25)28-20-12-16(11-19(26)22(20)21)14-5-3-2-4-6-14/h2-10,16,18,21,25H,11-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT3 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 3 (Homo sapiens (Human))	BDBM50293010 (2-amino-4-(4-(methylthio)phenyl)-5-oxo-7-phenyl-5,...) Show SMILES CSc1ccc(cc1)C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1ccccc1 |c:16| Show InChI InChI=1S/C23H20N2O2S/c1-28-17-9-7-15(8-10-17)21-18(13-24)23(25)27-20-12-16(11-19(26)22(20)21)14-5-3-2-4-6-14/h2-10,16,18,21,25H,11-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]D-Asp from human EAAT3 receptor expressed in HEK293 cells				J Med Chem 52: 912-5 (2009) Article DOI: 10.1021/jm8013458 BindingDB Entry DOI: 10.7270/Q2PV6KCP
					More data for this Ligand-Target Pair

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