Found 15 hits Enz. Inhib. hit(s) with all data for entry = 50031865 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM19130
((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 9.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem 18: 3925-33 (2010)
Article DOI: 10.1016/j.bmc.2010.04.033
BindingDB Entry DOI: 10.7270/Q29S1R6H |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM19410
(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)Show InChI InChI=1S/C21H20N4O3/c22-18-5-1-2-6-19(18)25-20(26)17-9-7-15(8-10-17)13-24-21(27)28-14-16-4-3-11-23-12-16/h1-12H,13-14,22H2,(H,24,27)(H,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem 18: 3925-33 (2010)
Article DOI: 10.1016/j.bmc.2010.04.033
BindingDB Entry DOI: 10.7270/Q29S1R6H |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50320762
(CHEMBL1164063 | N-(2-Aminophenyl)-4-(((biphenyl-4-...)Show SMILES Nc1ccccc1NC(=O)c1ccc(CN(CCO)Cc2ccc(cc2)-c2ccccc2)cc1 Show InChI InChI=1S/C29H29N3O2/c30-27-8-4-5-9-28(27)31-29(34)26-16-12-23(13-17-26)21-32(18-19-33)20-22-10-14-25(15-11-22)24-6-2-1-3-7-24/h1-17,33H,18-21,30H2,(H,31,34) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem 18: 3925-33 (2010)
Article DOI: 10.1016/j.bmc.2010.04.033
BindingDB Entry DOI: 10.7270/Q29S1R6H |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50320761
(CHEMBL1163973 | N-(2-Aminophenyl)-4-(((2-hydroxyet...)Show SMILES Nc1ccccc1NC(=O)c1ccc(CN(CCO)Cc2ccc(cc2)-c2cccs2)cc1 Show InChI InChI=1S/C27H27N3O2S/c28-24-4-1-2-5-25(24)29-27(32)23-13-9-21(10-14-23)19-30(15-16-31)18-20-7-11-22(12-8-20)26-6-3-17-33-26/h1-14,17,31H,15-16,18-19,28H2,(H,29,32) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem 18: 3925-33 (2010)
Article DOI: 10.1016/j.bmc.2010.04.033
BindingDB Entry DOI: 10.7270/Q29S1R6H |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50320760
(CHEMBL1165774 | N-(2-Aminophenyl)-4-((3,3-dimethyl...)Show SMILES CN(C)C(=O)N(Cc1ccc(cc1)C(=O)Nc1ccccc1N)Cc1ccc(cc1)-c1cccs1 Show InChI InChI=1S/C28H28N4O2S/c1-31(2)28(34)32(18-20-9-13-22(14-10-20)26-8-5-17-35-26)19-21-11-15-23(16-12-21)27(33)30-25-7-4-3-6-24(25)29/h3-17H,18-19,29H2,1-2H3,(H,30,33) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem 18: 3925-33 (2010)
Article DOI: 10.1016/j.bmc.2010.04.033
BindingDB Entry DOI: 10.7270/Q29S1R6H |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50320757
(CHEMBL1165443 | N-(2-aminophenyl)-4-((biphenyl-4-y...)Show SMILES Nc1ccccc1NC(=O)c1ccc(CNCc2ccc(cc2)-c2ccccc2)cc1 Show InChI InChI=1S/C27H25N3O/c28-25-8-4-5-9-26(25)30-27(31)24-16-12-21(13-17-24)19-29-18-20-10-14-23(15-11-20)22-6-2-1-3-7-22/h1-17,29H,18-19,28H2,(H,30,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem 18: 3925-33 (2010)
Article DOI: 10.1016/j.bmc.2010.04.033
BindingDB Entry DOI: 10.7270/Q29S1R6H |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50320754
(CHEMBL1163887 | N-(2-aminophenyl)-4-((4-(thiophen-...)Show SMILES Nc1ccccc1NC(=O)c1ccc(CNCc2ccc(cc2)-c2cccs2)cc1 Show InChI InChI=1S/C25H23N3OS/c26-22-4-1-2-5-23(22)28-25(29)21-13-9-19(10-14-21)17-27-16-18-7-11-20(12-8-18)24-6-3-15-30-24/h1-15,27H,16-17,26H2,(H,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem 18: 3925-33 (2010)
Article DOI: 10.1016/j.bmc.2010.04.033
BindingDB Entry DOI: 10.7270/Q29S1R6H |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50320755
(CHEMBL1165102 | N-(2-aminophenyl)-4-((benzo[b]thio...)Show InChI InChI=1S/C23H21N3OS/c24-20-6-2-3-7-21(20)26-23(27)17-11-9-16(10-12-17)14-25-15-19-13-18-5-1-4-8-22(18)28-19/h1-13,25H,14-15,24H2,(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem 18: 3925-33 (2010)
Article DOI: 10.1016/j.bmc.2010.04.033
BindingDB Entry DOI: 10.7270/Q29S1R6H |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50320759
(CHEMBL1164440 | N-(2-Aminophenyl)-4-((N-(4-(thioph...)Show SMILES CS(=O)(=O)N(Cc1ccc(cc1)C(=O)Nc1ccccc1N)Cc1ccc(cc1)-c1cccs1 Show InChI InChI=1S/C26H25N3O3S2/c1-34(31,32)29(17-19-8-12-21(13-9-19)25-7-4-16-33-25)18-20-10-14-22(15-11-20)26(30)28-24-6-3-2-5-23(24)27/h2-16H,17-18,27H2,1H3,(H,28,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem 18: 3925-33 (2010)
Article DOI: 10.1016/j.bmc.2010.04.033
BindingDB Entry DOI: 10.7270/Q29S1R6H |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50320756
(CHEMBL1164335 | N-(2-aminophenyl)-4-((3-(thiophen-...)Show SMILES Nc1ccccc1NC(=O)c1ccc(CNCc2cccc(c2)-c2cccs2)cc1 Show InChI InChI=1S/C25H23N3OS/c26-22-7-1-2-8-23(22)28-25(29)20-12-10-18(11-13-20)16-27-17-19-5-3-6-21(15-19)24-9-4-14-30-24/h1-15,27H,16-17,26H2,(H,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem 18: 3925-33 (2010)
Article DOI: 10.1016/j.bmc.2010.04.033
BindingDB Entry DOI: 10.7270/Q29S1R6H |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50320758
(CHEMBL1165580 | N-(2-Aminophenyl)-4-((methyl(4-(th...)Show SMILES CN(Cc1ccc(cc1)C(=O)Nc1ccccc1N)Cc1ccc(cc1)-c1cccs1 Show InChI InChI=1S/C26H25N3OS/c1-29(17-19-8-12-21(13-9-19)25-7-4-16-31-25)18-20-10-14-22(15-11-20)26(30)28-24-6-3-2-5-23(24)27/h2-16H,17-18,27H2,1H3,(H,28,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem 18: 3925-33 (2010)
Article DOI: 10.1016/j.bmc.2010.04.033
BindingDB Entry DOI: 10.7270/Q29S1R6H |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50320752
(CHEMBL1163807 | N-(2-Aminophenyl)-4-(((2,3-dihydro...)Show InChI InChI=1S/C23H22N2O3S/c24-19-5-1-2-6-20(19)25-23(26)17-11-9-16(10-12-17)14-29-15-18-13-27-21-7-3-4-8-22(21)28-18/h1-12,18H,13-15,24H2,(H,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem 18: 3925-33 (2010)
Article DOI: 10.1016/j.bmc.2010.04.033
BindingDB Entry DOI: 10.7270/Q29S1R6H |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50320753
(CHEMBL1163886 | N-(2-Aminophenyl)-4-((4-chlorobenz...)Show InChI InChI=1S/C21H19ClN2OS/c22-18-11-7-16(8-12-18)14-26-13-15-5-9-17(10-6-15)21(25)24-20-4-2-1-3-19(20)23/h1-12H,13-14,23H2,(H,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem 18: 3925-33 (2010)
Article DOI: 10.1016/j.bmc.2010.04.033
BindingDB Entry DOI: 10.7270/Q29S1R6H |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50320751
(CHEMBL1163806 | N-(2-Aminophenyl)-4-((naphthalen-2...)Show InChI InChI=1S/C25H22N2OS/c26-23-7-3-4-8-24(23)27-25(28)21-13-9-18(10-14-21)16-29-17-19-11-12-20-5-1-2-6-22(20)15-19/h1-15H,16-17,26H2,(H,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem 18: 3925-33 (2010)
Article DOI: 10.1016/j.bmc.2010.04.033
BindingDB Entry DOI: 10.7270/Q29S1R6H |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50320750
(CHEMBL1163553 | N-(2-Aminophenyl)-4-((naphthalen-2...)Show InChI InChI=1S/C24H20N2OS/c25-22-7-3-4-8-23(22)26-24(27)19-11-9-17(10-12-19)16-28-21-14-13-18-5-1-2-6-20(18)15-21/h1-15H,16,25H2,(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem 18: 3925-33 (2010)
Article DOI: 10.1016/j.bmc.2010.04.033
BindingDB Entry DOI: 10.7270/Q29S1R6H |
More data for this
Ligand-Target Pair | |
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