Found 40 hits Enz. Inhib. hit(s) with all data for entry = 50032271 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM11639
![PNG](/data/jpeg/tenK1/BindingDB_11639.png) (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) | PDB MMDB
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| PDB Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX2 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50326520
![PNG](/data/jpeg/tenK5032/BindingDB_50326520.png) (1-(4-(methylsulfonyl)phenyl)-1H-indole | CHEMBL124...)Show InChI InChI=1S/C15H13NO2S/c1-19(17,18)14-8-6-13(7-9-14)16-11-10-12-4-2-3-5-15(12)16/h2-11H,1H3 | PDB MMDB
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UniProtKB/SwissProt
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| Article PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX2 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM22369
![PNG](/data/jpeg/tenK2/BindingDB_22369.png) (4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...)Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 |t:11| Show InChI InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3 | PDB MMDB
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| n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX2 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50326527
![PNG](/data/jpeg/tenK5032/BindingDB_50326527.png) ((4-bromophenyl)(4-(methylsulfonyl)phenyl)methanone...)Show InChI InChI=1S/C14H11BrO3S/c1-19(17,18)13-8-4-11(5-9-13)14(16)10-2-6-12(15)7-3-10/h2-9H,1H3 | PDB MMDB
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UniProtKB/SwissProt
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| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX2 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50326525
![PNG](/data/jpeg/tenK5032/BindingDB_50326525.png) (2-(4-(methylsulfonyl)phenyl)pyridine | CHEMBL12409...)Show InChI InChI=1S/C12H11NO2S/c1-16(14,15)11-7-5-10(6-8-11)12-4-2-3-9-13-12/h2-9H,1H3 | PDB MMDB
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| Article PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX2 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50169047
![PNG](/data/jpeg/tenK5016/BindingDB_50169047.png) ((S)-2-(4-Isobutyl-phenyl)-propionic acid | (S)-2-(...)Show InChI InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)/t10-/m0/s1 | PDB MMDB
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| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX2 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50326523
![PNG](/data/jpeg/tenK5032/BindingDB_50326523.png) (4-fluoro-N-(4-(methylsulfonyl)phenyl)aniline | CHE...)Show InChI InChI=1S/C13H12FNO2S/c1-18(16,17)13-8-6-12(7-9-13)15-11-4-2-10(14)3-5-11/h2-9,15H,1H3 | PDB MMDB
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UniProtKB/SwissProt
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| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX2 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50169047
![PNG](/data/jpeg/tenK5016/BindingDB_50169047.png) ((S)-2-(4-Isobutyl-phenyl)-propionic acid | (S)-2-(...)Show InChI InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)/t10-/m0/s1 | PDB
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| n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX1 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50326534
![PNG](/data/jpeg/tenK5032/BindingDB_50326534.png) (CHEMBL1240537 | furan-3-yl(4-(methylsulfonyl)pheny...)Show InChI InChI=1S/C12H10O4S/c1-17(14,15)11-4-2-9(3-5-11)12(13)10-6-7-16-8-10/h2-8H,1H3 | PDB MMDB
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| Article PubMed
| n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX2 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM11639
![PNG](/data/jpeg/tenK1/BindingDB_11639.png) (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) | PDB
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| n/a | n/a | 6.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX1 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50326526
![PNG](/data/jpeg/tenK5032/BindingDB_50326526.png) ((4-fluorophenyl)(4-(methylsulfonyl)phenyl)methanon...)Show InChI InChI=1S/C14H11FO3S/c1-19(17,18)13-8-4-11(5-9-13)14(16)10-2-6-12(15)7-3-10/h2-9H,1H3 | PDB MMDB
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| n/a | n/a | 7.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX2 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50326521
![PNG](/data/jpeg/tenK5032/BindingDB_50326521.png) (1-(4-(methylsulfonyl)phenyl)-1H-pyrrole | CHEMBL12...)Show InChI InChI=1S/C11H11NO2S/c1-15(13,14)11-6-4-10(5-7-11)12-8-2-3-9-12/h2-9H,1H3 | PDB MMDB
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| n/a | n/a | 8.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX2 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50326530
![PNG](/data/jpeg/tenK5032/BindingDB_50326530.png) ((1H-indol-3-yl)(4-(methylsulfonyl)phenyl)methanone...)Show InChI InChI=1S/C16H13NO3S/c1-21(19,20)12-8-6-11(7-9-12)16(18)14-10-17-15-5-3-2-4-13(14)15/h2-10,17H,1H3 | PDB MMDB
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| Article PubMed
| n/a | n/a | 9.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX2 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50029593
![PNG](/data/jpeg/tenK5002/BindingDB_50029593.png) (CHEMBL7162 | N-(2-(cyclohexyloxy)-4-nitrophenyl)me...)Show InChI InChI=1S/C13H18N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h7-9,11,14H,2-6H2,1H3 | PDB
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| n/a | n/a | 1.41E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX1 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50326535
![PNG](/data/jpeg/tenK5032/BindingDB_50326535.png) (2-(p-Methylsulfonylbenzoyl)furan | CHEMBL1240887)Show InChI InChI=1S/C12H10O4S/c1-17(14,15)10-6-4-9(5-7-10)12(13)11-3-2-8-16-11/h2-8H,1H3 | PDB
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| Article PubMed
| n/a | n/a | 1.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX1 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50326528
![PNG](/data/jpeg/tenK5032/BindingDB_50326528.png) ((4-(methylsulfonyl)phenyl)(thiophen-3-yl)methanone...)Show InChI InChI=1S/C12H10O3S2/c1-17(14,15)11-4-2-9(3-5-11)12(13)10-6-7-16-8-10/h2-8H,1H3 | PDB MMDB
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| n/a | n/a | 1.52E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX2 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50326522
![PNG](/data/jpeg/tenK5032/BindingDB_50326522.png) (1-(4-fluorophenyl)-4-(4-(methylsulfonyl)phenyl)pip...)Show InChI InChI=1S/C17H19FN2O2S/c1-23(21,22)17-8-6-16(7-9-17)20-12-10-19(11-13-20)15-4-2-14(18)3-5-15/h2-9H,10-13H2,1H3 | PDB MMDB
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| Article PubMed
| n/a | n/a | 1.88E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX2 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50326535
![PNG](/data/jpeg/tenK5032/BindingDB_50326535.png) (2-(p-Methylsulfonylbenzoyl)furan | CHEMBL1240887)Show InChI InChI=1S/C12H10O4S/c1-17(14,15)10-6-4-9(5-7-10)12(13)11-3-2-8-16-11/h2-8H,1H3 | PDB MMDB
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| Article PubMed
| n/a | n/a | 1.92E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX2 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50326531
![PNG](/data/jpeg/tenK5032/BindingDB_50326531.png) ((1-(2-fluorophenyl)-1H-pyrrol-3-yl)(4-(methylsulfo...)Show SMILES CS(=O)(=O)c1ccc(cc1)C(=O)c1ccn(c1)-c1ccccc1F Show InChI InChI=1S/C18H14FNO3S/c1-24(22,23)15-8-6-13(7-9-15)18(21)14-10-11-20(12-14)17-5-3-2-4-16(17)19/h2-12H,1H3 | PDB MMDB
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| Article PubMed
| n/a | n/a | 1.97E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX2 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50326529
![PNG](/data/jpeg/tenK5032/BindingDB_50326529.png) (2-(p-Methylsulfonylbenzoyl)thiophene | CHEMBL12408...)Show InChI InChI=1S/C12H10O3S2/c1-17(14,15)10-6-4-9(5-7-10)12(13)11-3-2-8-16-11/h2-8H,1H3 | PDB MMDB
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| Article PubMed
| n/a | n/a | 2.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX2 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM22369
![PNG](/data/jpeg/tenK2/BindingDB_22369.png) (4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...)Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 |t:11| Show InChI InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3 | PDB
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| Article PubMed
| n/a | n/a | 2.35E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX1 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50326524
![PNG](/data/jpeg/tenK5032/BindingDB_50326524.png) (4-(4-(methylsulfonyl)phenyl)-4H-benzo[b]pyrrolo[1,...)Show InChI InChI=1S/C18H15NO3S/c1-23(20,21)14-10-8-13(9-11-14)18-16-6-4-12-19(16)15-5-2-3-7-17(15)22-18/h2-12,18H,1H3 | PDB MMDB
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| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.65E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX2 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50326530
![PNG](/data/jpeg/tenK5032/BindingDB_50326530.png) ((1H-indol-3-yl)(4-(methylsulfonyl)phenyl)methanone...)Show InChI InChI=1S/C16H13NO3S/c1-21(19,20)12-8-6-11(7-9-12)16(18)14-10-17-15-5-3-2-4-13(14)15/h2-10,17H,1H3 | PDB
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UniProtKB/SwissProt
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Similars
| Article PubMed
| n/a | n/a | 2.67E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX1 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50326531
![PNG](/data/jpeg/tenK5032/BindingDB_50326531.png) ((1-(2-fluorophenyl)-1H-pyrrol-3-yl)(4-(methylsulfo...)Show SMILES CS(=O)(=O)c1ccc(cc1)C(=O)c1ccn(c1)-c1ccccc1F Show InChI InChI=1S/C18H14FNO3S/c1-24(22,23)15-8-6-13(7-9-15)18(21)14-10-11-20(12-14)17-5-3-2-4-16(17)19/h2-12H,1H3 | PDB
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UniProtKB/SwissProt
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| n/a | n/a | 3.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX1 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50326533
![PNG](/data/jpeg/tenK5032/BindingDB_50326533.png) ((1-methyl-1H-indol-3-yl)(4-(methylsulfonyl)phenyl)...)Show InChI InChI=1S/C17H15NO3S/c1-18-11-15(14-5-3-4-6-16(14)18)17(19)12-7-9-13(10-8-12)22(2,20)21/h3-11H,1-2H3 | PDB MMDB
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UniProtKB/SwissProt
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| Article PubMed
| n/a | n/a | 3.68E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX2 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50326532
![PNG](/data/jpeg/tenK5032/BindingDB_50326532.png) ((1-(2-fluorophenyl)-1H-pyrrol-2-yl)(4-(methylsulfo...)Show InChI InChI=1S/C18H14FNO3S/c1-24(22,23)14-10-8-13(9-11-14)18(21)17-7-4-12-20(17)16-6-3-2-5-15(16)19/h2-12H,1H3 | PDB MMDB
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UniProtKB/SwissProt
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| Article PubMed
| n/a | n/a | 4.33E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX2 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50029593
![PNG](/data/jpeg/tenK5002/BindingDB_50029593.png) (CHEMBL7162 | N-(2-(cyclohexyloxy)-4-nitrophenyl)me...)Show InChI InChI=1S/C13H18N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h7-9,11,14H,2-6H2,1H3 | PDB MMDB
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| PDB Article PubMed
| n/a | n/a | 7.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX2 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (crystal) |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50326533
![PNG](/data/jpeg/tenK5032/BindingDB_50326533.png) ((1-methyl-1H-indol-3-yl)(4-(methylsulfonyl)phenyl)...)Show InChI InChI=1S/C17H15NO3S/c1-18-11-15(14-5-3-4-6-16(14)18)17(19)12-7-9-13(10-8-12)22(2,20)21/h3-11H,1-2H3 | PDB
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UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.64E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX1 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50326520
![PNG](/data/jpeg/tenK5032/BindingDB_50326520.png) (1-(4-(methylsulfonyl)phenyl)-1H-indole | CHEMBL124...)Show InChI InChI=1S/C15H13NO2S/c1-19(17,18)14-8-6-13(7-9-14)16-11-10-12-4-2-3-5-15(12)16/h2-11H,1H3 | PDB
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UniProtKB/SwissProt
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| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 7.87E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX1 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50326522
![PNG](/data/jpeg/tenK5032/BindingDB_50326522.png) (1-(4-fluorophenyl)-4-(4-(methylsulfonyl)phenyl)pip...)Show InChI InChI=1S/C17H19FN2O2S/c1-23(21,22)17-8-6-16(7-9-17)20-12-10-19(11-13-20)15-4-2-14(18)3-5-15/h2-9H,10-13H2,1H3 | PDB
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UniProtKB/SwissProt
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| CHEMBL PC cid PC sid UniChem
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| n/a | n/a | 8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX1 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50326521
![PNG](/data/jpeg/tenK5032/BindingDB_50326521.png) (1-(4-(methylsulfonyl)phenyl)-1H-pyrrole | CHEMBL12...)Show InChI InChI=1S/C11H11NO2S/c1-15(13,14)11-6-4-10(5-7-11)12-8-2-3-9-12/h2-9H,1H3 | PDB
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| n/a | n/a | 8.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX1 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50326525
![PNG](/data/jpeg/tenK5032/BindingDB_50326525.png) (2-(4-(methylsulfonyl)phenyl)pyridine | CHEMBL12409...)Show InChI InChI=1S/C12H11NO2S/c1-16(14,15)11-7-5-10(6-8-11)12-4-2-3-9-13-12/h2-9H,1H3 | PDB
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UniProtKB/SwissProt
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| Article PubMed
| n/a | n/a | 8.96E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX1 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50326526
![PNG](/data/jpeg/tenK5032/BindingDB_50326526.png) ((4-fluorophenyl)(4-(methylsulfonyl)phenyl)methanon...)Show InChI InChI=1S/C14H11FO3S/c1-19(17,18)13-8-4-11(5-9-13)14(16)10-2-6-12(15)7-3-10/h2-9H,1H3 | PDB
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| n/a | n/a | 1.07E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX1 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50326523
![PNG](/data/jpeg/tenK5032/BindingDB_50326523.png) (4-fluoro-N-(4-(methylsulfonyl)phenyl)aniline | CHE...)Show InChI InChI=1S/C13H12FNO2S/c1-18(16,17)13-8-6-12(7-9-13)15-11-4-2-10(14)3-5-11/h2-9,15H,1H3 | PDB
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UniProtKB/SwissProt
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| Article PubMed
| n/a | n/a | 1.41E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX1 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50326528
![PNG](/data/jpeg/tenK5032/BindingDB_50326528.png) ((4-(methylsulfonyl)phenyl)(thiophen-3-yl)methanone...)Show InChI InChI=1S/C12H10O3S2/c1-17(14,15)11-4-2-9(3-5-11)12(13)10-6-7-16-8-10/h2-8H,1H3 | PDB
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UniProtKB/SwissProt
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| n/a | n/a | 1.44E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX1 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50326527
![PNG](/data/jpeg/tenK5032/BindingDB_50326527.png) ((4-bromophenyl)(4-(methylsulfonyl)phenyl)methanone...)Show InChI InChI=1S/C14H11BrO3S/c1-19(17,18)13-8-4-11(5-9-13)14(16)10-2-6-12(15)7-3-10/h2-9H,1H3 | PDB
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| Article PubMed
| n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX1 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50326534
![PNG](/data/jpeg/tenK5032/BindingDB_50326534.png) (CHEMBL1240537 | furan-3-yl(4-(methylsulfonyl)pheny...)Show InChI InChI=1S/C12H10O4S/c1-17(14,15)11-4-2-9(3-5-11)12(13)10-6-7-16-8-10/h2-8H,1H3 | PDB
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UniProtKB/SwissProt
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| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX1 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50326524
![PNG](/data/jpeg/tenK5032/BindingDB_50326524.png) (4-(4-(methylsulfonyl)phenyl)-4H-benzo[b]pyrrolo[1,...)Show InChI InChI=1S/C18H15NO3S/c1-23(20,21)14-10-8-13(9-11-14)18-16-6-4-12-19(16)15-5-2-3-7-17(15)22-18/h2-12,18H,1H3 | PDB
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UniProtKB/SwissProt
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| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.77E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX1 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50326532
![PNG](/data/jpeg/tenK5032/BindingDB_50326532.png) ((1-(2-fluorophenyl)-1H-pyrrol-2-yl)(4-(methylsulfo...)Show InChI InChI=1S/C18H14FNO3S/c1-24(22,23)14-10-8-13(9-11-14)18(21)17-7-4-12-20(17)16-6-3-2-5-15(16)19/h2-12H,1H3 | PDB
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UniProtKB/SwissProt
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| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.83E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX1 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50326529
![PNG](/data/jpeg/tenK5032/BindingDB_50326529.png) (2-(p-Methylsulfonylbenzoyl)thiophene | CHEMBL12408...)Show InChI InChI=1S/C12H10O3S2/c1-17(14,15)10-6-4-9(5-7-10)12(13)11-3-2-8-16-11/h2-8H,1H3 | PDB
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Patents
| Article PubMed
| n/a | n/a | 2.31E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of sheep COX1 by spectrophotometry |
J Med Chem 53: 6560-71 (2010)
Article DOI: 10.1021/jm100398z BindingDB Entry DOI: 10.7270/Q21R6QQW |
More data for this Ligand-Target Pair | |