BindingDB PrimarySearch

Found 28 hits Enz. Inhib. hit(s) with all data for entry = 50032361
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Integrin alpha-V/beta-5 (Homo sapiens (Human))	BDBM50327751 ((S)-3-{2-[4-(3-Guanidinopropyl)[1,2,3]triazol-1-yl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta5				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-5 (Homo sapiens (Human))	BDBM50327755 ((S)-3-(2-{4-[2-(4-Carbamimidoylpiperazin-1-yl)ethy...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta5				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50327751 ((S)-3-{2-[4-(3-Guanidinopropyl)[1,2,3]triazol-1-yl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta3				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-5 (Homo sapiens (Human))	BDBM50327749 ((S)-3-[2-(4-Guanidinomethyl[1,2,3]triazol-1-yl)ace...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta5				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-5 (Homo sapiens (Human))	BDBM50327753 ((R)-3-(2-{4-[2-(4-Carbamimidoylpiperazin-1-yl)ethy...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta5				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50327750 ((S)-3-{2-[4-(2-Guanidinoethyl)[1,2,3]triazol-1-yl]...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta3				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-5 (Homo sapiens (Human))	BDBM50327750 ((S)-3-{2-[4-(2-Guanidinoethyl)[1,2,3]triazol-1-yl]...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta5				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50327753 ((R)-3-(2-{4-[2-(4-Carbamimidoylpiperazin-1-yl)ethy...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta3				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50327754 ((S)-3-{2-[4-(4-Carbamimidoylpiperazin-1-ylmethyl)[...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta3				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50327755 ((S)-3-(2-{4-[2-(4-Carbamimidoylpiperazin-1-yl)ethy...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta3				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-5 (Homo sapiens (Human))	BDBM50327742 (CHEMBL1257508 \| {[2-(4-Guanidinomethyl[1,2,3]triaz...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta5				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-5 (Homo sapiens (Human))	BDBM50327743 (({2-[4-(2-Guanidinoethyl)[1,2,3]triazol-1-yl]acety...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta5				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-5 (Homo sapiens (Human))	BDBM50327744 (({2-[4-(3-Guanidinopropyl)[1,2,3]triazol-1-yl]acet...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta5				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-5 (Homo sapiens (Human))	BDBM50327745 (CHEMBL1257627 \| [(2-{4-[2-(4-Carbamimidoylpiperazi...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta5				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-5 (Homo sapiens (Human))	BDBM50327746 ((R)-3-[2-(4-Guanidinomethyl[1,2,3]triazol-1-yl)ace...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta5				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-5 (Homo sapiens (Human))	BDBM50327747 ((R)-3-{2-[4-(2-Guanidinoethyl)[1,2,3]triazol-1-yl]...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta5				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-5 (Homo sapiens (Human))	BDBM50327752 ((R)-3-{2-[4-(4-Carbamimidoylpiperazin-1-ylmethyl)[...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta5				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50327752 ((R)-3-{2-[4-(4-Carbamimidoylpiperazin-1-ylmethyl)[...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta3				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50327749 ((S)-3-[2-(4-Guanidinomethyl[1,2,3]triazol-1-yl)ace...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta3				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50327748 ((R)-3-{2-[4-(3-Guanidinopropyl)[1,2,3]triazol-1-yl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta3				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50327747 ((R)-3-{2-[4-(2-Guanidinoethyl)[1,2,3]triazol-1-yl]...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta3				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50327746 ((R)-3-[2-(4-Guanidinomethyl[1,2,3]triazol-1-yl)ace...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta3				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50327745 (CHEMBL1257627 \| [(2-{4-[2-(4-Carbamimidoylpiperazi...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta3				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50327744 (({2-[4-(3-Guanidinopropyl)[1,2,3]triazol-1-yl]acet...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta3				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50327742 (CHEMBL1257508 \| {[2-(4-Guanidinomethyl[1,2,3]triaz...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta3				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50327743 (({2-[4-(2-Guanidinoethyl)[1,2,3]triazol-1-yl]acety...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta3				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-5 (Homo sapiens (Human))	BDBM50327754 ((S)-3-{2-[4-(4-Carbamimidoylpiperazin-1-ylmethyl)[...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta5				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-5 (Homo sapiens (Human))	BDBM50327748 ((R)-3-{2-[4-(3-Guanidinopropyl)[1,2,3]triazol-1-yl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from human integrin alphaVbeta5				J Med Chem 53: 7119-28 (2010) Article DOI: 10.1021/jm100754z BindingDB Entry DOI: 10.7270/Q2R211NF
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair