BindingDB PrimarySearch

Found 12 hits Enz. Inhib. hit(s) with all data for entry = 50033021
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of human recombinant COX-2 by fluorescence assay				Bioorg Med Chem Lett 21: 1823-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.057 BindingDB Entry DOI: 10.7270/Q2KD1Z6P
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50338296 (1-(4-methoxyphenyl)-5-(4-(methylsulfonyl)phenyl)-1...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of human recombinant COX-2 by fluorescence assay				Bioorg Med Chem Lett 21: 1823-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.057 BindingDB Entry DOI: 10.7270/Q2KD1Z6P
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50338297 (1-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)-1H...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of human recombinant COX-2 by fluorescence assay				Bioorg Med Chem Lett 21: 1823-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.057 BindingDB Entry DOI: 10.7270/Q2KD1Z6P
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	9.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of ovine COX-1 by fluorescence assay				Bioorg Med Chem Lett 21: 1823-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.057 BindingDB Entry DOI: 10.7270/Q2KD1Z6P
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50338295 (5-(4-(methylsulfonyl)phenyl)-1-p-tolyl-1H-tetrazol...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of human recombinant COX-2 by fluorescence assay				Bioorg Med Chem Lett 21: 1823-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.057 BindingDB Entry DOI: 10.7270/Q2KD1Z6P
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50338298 (1-(4-chlorophenyl)-5-(4-(methylsulfonyl)phenyl)-1H...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of human recombinant COX-2 by fluorescence assay				Bioorg Med Chem Lett 21: 1823-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.057 BindingDB Entry DOI: 10.7270/Q2KD1Z6P
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50338294 (5-(4-(methylsulfonyl)phenyl)-1-phenyl-1H-tetrazole...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1nnnn1-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of human recombinant COX-2 by fluorescence assay				Bioorg Med Chem Lett 21: 1823-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.057 BindingDB Entry DOI: 10.7270/Q2KD1Z6P
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50338296 (1-(4-methoxyphenyl)-5-(4-(methylsulfonyl)phenyl)-1...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of ovine COX-1 by fluorescence assay				Bioorg Med Chem Lett 21: 1823-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.057 BindingDB Entry DOI: 10.7270/Q2KD1Z6P
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50338298 (1-(4-chlorophenyl)-5-(4-(methylsulfonyl)phenyl)-1H...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of ovine COX-1 by fluorescence assay				Bioorg Med Chem Lett 21: 1823-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.057 BindingDB Entry DOI: 10.7270/Q2KD1Z6P
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50338297 (1-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)-1H...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of ovine COX-1 by fluorescence assay				Bioorg Med Chem Lett 21: 1823-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.057 BindingDB Entry DOI: 10.7270/Q2KD1Z6P
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50338294 (5-(4-(methylsulfonyl)phenyl)-1-phenyl-1H-tetrazole...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1nnnn1-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of ovine COX-1 by fluorescence assay				Bioorg Med Chem Lett 21: 1823-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.057 BindingDB Entry DOI: 10.7270/Q2KD1Z6P
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50338295 (5-(4-(methylsulfonyl)phenyl)-1-p-tolyl-1H-tetrazol...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of ovine COX-1 by fluorescence assay				Bioorg Med Chem Lett 21: 1823-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.057 BindingDB Entry DOI: 10.7270/Q2KD1Z6P
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair