Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Chitinase (Onchocerca volvulus) | BDBM50063753![]() (CHEMBL12131 | Closantel | N-(5-chloro-4-((4-chloro...) | UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 468 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Skaggs Institute for Chemical Biology Curated by ChEMBL | Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m... | J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitinase (Onchocerca volvulus) | BDBM50347553![]() (CHEMBL1801794) | UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 630 | n/a | n/a | n/a | n/a | n/a | n/a |
The Skaggs Institute for Chemical Biology Curated by ChEMBL | Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m... | J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitinase (Onchocerca volvulus) | BDBM50347552![]() (CHEMBL391125) | UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
The Skaggs Institute for Chemical Biology Curated by ChEMBL | Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m... | J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitinase (Onchocerca volvulus) | BDBM50347551![]() (CHEMBL395873) | UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 880 | n/a | n/a | n/a | n/a | n/a | n/a |
The Skaggs Institute for Chemical Biology Curated by ChEMBL | Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m... | J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitinase (Onchocerca volvulus) | BDBM50063753![]() (CHEMBL12131 | Closantel | N-(5-chloro-4-((4-chloro...) | UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Skaggs Institute for Chemical Biology Curated by ChEMBL | Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m... | J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitinase (Onchocerca volvulus) | BDBM50347554![]() (CHEMBL1801795) | UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Skaggs Institute for Chemical Biology Curated by ChEMBL | Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m... | J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitinase (Onchocerca volvulus) | BDBM50347549![]() (CHEMBL482487) | UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Skaggs Institute for Chemical Biology Curated by ChEMBL | Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m... | J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitinase (Onchocerca volvulus) | BDBM50347555![]() (3,5-Dibromo-2-hydroxy-N-(4-methoxyphenyl)benzamide...) | UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Skaggs Institute for Chemical Biology Curated by ChEMBL | Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m... | J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitinase (Onchocerca volvulus) | BDBM50347548![]() (CHEMBL237819) | UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Skaggs Institute for Chemical Biology Curated by ChEMBL | Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m... | J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitinase (Onchocerca volvulus) | BDBM50347550![]() (CHEMBL484912) | UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Skaggs Institute for Chemical Biology Curated by ChEMBL | Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m... | J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitinase (Onchocerca volvulus) | BDBM50065988![]() (3,5-Dichloro-N-(4-chloro-phenyl)-2-hydroxy-benzami...) | UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.24E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Skaggs Institute for Chemical Biology Curated by ChEMBL | Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m... | J Med Chem 54: 3963-72 (2011) Article DOI: 10.1021/jm200364n BindingDB Entry DOI: 10.7270/Q21V5FB9 | |||||||||||
More data for this Ligand-Target Pair |