Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human)) | BDBM50361151![]() (CHEMBL1933805) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Second Military Medical University Curated by ChEMBL | Assay Description Inhibition of GST-tagged human DYRK1A using dephosphorylated MBP as substrate after 10 mins by Kinase-Glo plus luminescent kinase assay | Bioorg Med Chem Lett 22: 168-71 (2011) Article DOI: 10.1016/j.bmcl.2011.11.043 BindingDB Entry DOI: 10.7270/Q2MS3T6W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human)) | BDBM50361149![]() (CHEMBL1933803) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Second Military Medical University Curated by ChEMBL | Assay Description Inhibition of GST-tagged human DYRK1A using dephosphorylated MBP as substrate after 10 mins by Kinase-Glo plus luminescent kinase assay | Bioorg Med Chem Lett 22: 168-71 (2011) Article DOI: 10.1016/j.bmcl.2011.11.043 BindingDB Entry DOI: 10.7270/Q2MS3T6W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human)) | BDBM50070942![]() ((-)-Epigallocatechin gallate | (-)-Epigallocatechi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Second Military Medical University Curated by ChEMBL | Assay Description Inhibition of GST-tagged human DYRK1A using dephosphorylated MBP as substrate after 10 mins by Kinase-Glo plus luminescent kinase assay | Bioorg Med Chem Lett 22: 168-71 (2011) Article DOI: 10.1016/j.bmcl.2011.11.043 BindingDB Entry DOI: 10.7270/Q2MS3T6W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human)) | BDBM50361150![]() (CHEMBL1933804) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.95E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Second Military Medical University Curated by ChEMBL | Assay Description Inhibition of GST-tagged human DYRK1A using dephosphorylated MBP as substrate after 10 mins by Kinase-Glo plus luminescent kinase assay | Bioorg Med Chem Lett 22: 168-71 (2011) Article DOI: 10.1016/j.bmcl.2011.11.043 BindingDB Entry DOI: 10.7270/Q2MS3T6W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human)) | BDBM50361152![]() (CHEMBL1933806) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.37E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Second Military Medical University Curated by ChEMBL | Assay Description Inhibition of GST-tagged human DYRK1A using dephosphorylated MBP as substrate after 10 mins by Kinase-Glo plus luminescent kinase assay | Bioorg Med Chem Lett 22: 168-71 (2011) Article DOI: 10.1016/j.bmcl.2011.11.043 BindingDB Entry DOI: 10.7270/Q2MS3T6W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human)) | BDBM50361148![]() (CHEMBL1933802) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.47E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Second Military Medical University Curated by ChEMBL | Assay Description Inhibition of GST-tagged human DYRK1A using dephosphorylated MBP as substrate after 10 mins by Kinase-Glo plus luminescent kinase assay | Bioorg Med Chem Lett 22: 168-71 (2011) Article DOI: 10.1016/j.bmcl.2011.11.043 BindingDB Entry DOI: 10.7270/Q2MS3T6W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human)) | BDBM50361147![]() (CHEMBL1933801) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.81E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Second Military Medical University Curated by ChEMBL | Assay Description Inhibition of GST-tagged human DYRK1A using dephosphorylated MBP as substrate after 10 mins by Kinase-Glo plus luminescent kinase assay | Bioorg Med Chem Lett 22: 168-71 (2011) Article DOI: 10.1016/j.bmcl.2011.11.043 BindingDB Entry DOI: 10.7270/Q2MS3T6W | |||||||||||
More data for this Ligand-Target Pair |