Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50000558 (CHEMBL437472 | ET-1 | Endothelin -1 | Endothelin 1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with recombinant human ETA receptor, expressed in baculovirus-infected Sf9 cells | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50000558 (CHEMBL437472 | ET-1 | Endothelin -1 | Endothelin 1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with membranes prepared from human placenta for ETB receptor | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50290050 (CHEMBL70385 | Pyridin-2-yl-carbamic acid 2-[5-(2-m...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with recombinant human ETA receptor, expressed in baculovirus-infected Sf9 cells | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50290043 (CHEMBL72037 | Pyridin-2-yl-carbamic acid 2-[6-(5-i...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with recombinant human ETA receptor, expressed in baculovirus-infected Sf9 cells | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50000558 (CHEMBL437472 | ET-1 | Endothelin -1 | Endothelin 1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Evaluation for functional inhibitory potency prevention of ET-1 induced constriction of rat aortic rings (ETA receptors) | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50290043 (CHEMBL72037 | Pyridin-2-yl-carbamic acid 2-[6-(5-i...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Evaluation for functional inhibitory potency prevention of ET-1 induced constriction of rat aortic rings (ETA receptors) | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50290047 (CHEMBL308088 | Pyridin-2-yl-carbamic acid 2-[6-(5-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with recombinant human ETA receptor, expressed in baculovirus-infected Sf9 cells | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50290059 (CHEMBL70895 | Pyridin-2-yl-carbamic acid 2-[6-(5-i...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with recombinant human ETA receptor, expressed in baculovirus-infected Sf9 cells | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50290060 (CHEMBL70293 | Pyridin-2-yl-carbamic acid 2-[6-(5-i...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with recombinant human ETA receptor, expressed in baculovirus-infected Sf9 cells | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50290057 (CHEMBL70303 | Pyridin-2-yl-carbamic acid 2-[5-(2-m...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with recombinant human ETA receptor, expressed in baculovirus-infected Sf9 cells | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50290043 (CHEMBL72037 | Pyridin-2-yl-carbamic acid 2-[6-(5-i...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with membranes prepared from human placenta for ETB receptor | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50290041 (CHEMBL70203 | Pyridin-2-yl-carbamic acid 2-[6-(4-t...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with recombinant human ETA receptor, expressed in baculovirus-infected Sf9 cells | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50290044 (CHEMBL70800 | Pyridin-2-yl-carbamic acid 2-[6-(4-t...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with recombinant human ETA receptor, expressed in baculovirus-infected Sf9 cells | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50290042 (CHEMBL70487 | Pyridin-2-yl-carbamic acid 2-[6-(4-t...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with recombinant human ETA receptor, expressed in baculovirus-infected Sf9 cells | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50290049 (CHEMBL71070 | Pyridin-2-yl-carbamic acid 2-[6-(4-t...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with recombinant human ETA receptor, expressed in baculovirus-infected Sf9 cells | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50290055 (CHEMBL303428 | Pyridin-2-yl-carbamic acid 2-[6-(4-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with recombinant human ETA receptor, expressed in baculovirus-infected Sf9 cells | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50290047 (CHEMBL308088 | Pyridin-2-yl-carbamic acid 2-[6-(5-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with membranes prepared from human placenta for ETB receptor | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50290051 (CHEMBL303649 | Pyridin-2-yl-carbamic acid 2-[2-ter...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with recombinant human ETA receptor, expressed in baculovirus-infected Sf9 cells | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50290053 (CHEMBL70339 | Pyridin-2-yl-carbamic acid 2-[6-(4-t...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with recombinant human ETA receptor, expressed in baculovirus-infected Sf9 cells | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50290053 (CHEMBL70339 | Pyridin-2-yl-carbamic acid 2-[6-(4-t...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with membranes prepared from human placenta for ETB receptor | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50290050 (CHEMBL70385 | Pyridin-2-yl-carbamic acid 2-[5-(2-m...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with membranes prepared from human placenta for ETB receptor | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50290059 (CHEMBL70895 | Pyridin-2-yl-carbamic acid 2-[6-(5-i...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with membranes prepared from human placenta for ETB receptor | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50290061 (CHEMBL70365 | Pyridin-2-yl-carbamic acid 2-[6-(4-t...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with recombinant human ETA receptor, expressed in baculovirus-infected Sf9 cells | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50290041 (CHEMBL70203 | Pyridin-2-yl-carbamic acid 2-[6-(4-t...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with membranes prepared from human placenta for ETB receptor | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50290060 (CHEMBL70293 | Pyridin-2-yl-carbamic acid 2-[6-(5-i...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with membranes prepared from human placenta for ETB receptor | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50290042 (CHEMBL70487 | Pyridin-2-yl-carbamic acid 2-[6-(4-t...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with membranes prepared from human placenta for ETB receptor | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50290055 (CHEMBL303428 | Pyridin-2-yl-carbamic acid 2-[6-(4-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with membranes prepared from human placenta for ETB receptor | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50290045 (4-tert-Butyl-N-[6-(2-hydroxy-ethoxy)-5-(2-methoxy-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with membranes prepared from human placenta for ETB receptor | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50061101 (4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with recombinant human ETA receptor, expressed in baculovirus-infected Sf9 cells | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50061101 (4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Evaluation for functional inhibitory potency prevention of ET-1 induced constriction of rat aortic rings (ETA receptors) | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50290058 (4-tert-Butyl-N-{5-(2-methoxy-phenoxy)-2-methyl-6-[...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with recombinant human ETA receptor, expressed in baculovirus-infected Sf9 cells | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50290044 (CHEMBL70800 | Pyridin-2-yl-carbamic acid 2-[6-(4-t...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with membranes prepared from human placenta for ETB receptor | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50290051 (CHEMBL303649 | Pyridin-2-yl-carbamic acid 2-[2-ter...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 144 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with membranes prepared from human placenta for ETB receptor | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50061101 (4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with membranes prepared from human placenta for ETB receptor | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50290049 (CHEMBL71070 | Pyridin-2-yl-carbamic acid 2-[6-(4-t...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with membranes prepared from human placenta for ETB receptor | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50290057 (CHEMBL70303 | Pyridin-2-yl-carbamic acid 2-[5-(2-m...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with membranes prepared from human placenta for ETB receptor | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50290061 (CHEMBL70365 | Pyridin-2-yl-carbamic acid 2-[6-(4-t...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with membranes prepared from human placenta for ETB receptor | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50290054 (CHEMBL435895 | Methylamino-acetic acid 2-[6-(4-ter...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with membranes prepared from human placenta for ETB receptor | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50290046 (CHEMBL70788 | Pyridin-3-yl-carbamic acid 2-[6-(4-t...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with membranes prepared from human placenta for ETB receptor | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50290048 (CHEMBL70781 | Nicotinic acid 2-[6-(4-tert-butyl-be...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 770 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with membranes prepared from human placenta for ETB receptor | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50290048 (CHEMBL70781 | Nicotinic acid 2-[6-(4-tert-butyl-be...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 880 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with recombinant human ETA receptor, expressed in baculovirus-infected Sf9 cells | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50290046 (CHEMBL70788 | Pyridin-3-yl-carbamic acid 2-[6-(4-t...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with recombinant human ETA receptor, expressed in baculovirus-infected Sf9 cells | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50290052 (CHEMBL74118 | Furan-3-carboxylic acid 2-[6-(4-tert...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with membranes prepared from human placenta for ETB receptor | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50290052 (CHEMBL74118 | Furan-3-carboxylic acid 2-[6-(4-tert...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with recombinant human ETA receptor, expressed in baculovirus-infected Sf9 cells | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50290058 (4-tert-Butyl-N-{5-(2-methoxy-phenoxy)-2-methyl-6-[...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 1.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with membranes prepared from human placenta for ETB receptor | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50290045 (4-tert-Butyl-N-[6-(2-hydroxy-ethoxy)-5-(2-methoxy-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with recombinant human ETA receptor, expressed in baculovirus-infected Sf9 cells | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50290054 (CHEMBL435895 | Methylamino-acetic acid 2-[6-(4-ter...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with recombinant human ETA receptor, expressed in baculovirus-infected Sf9 cells | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50290056 (CHEMBL307803 | Pyridin-4-yl-carbamic acid 2-[6-(4-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with recombinant human ETA receptor, expressed in baculovirus-infected Sf9 cells | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50290056 (CHEMBL307803 | Pyridin-4-yl-carbamic acid 2-[6-(4-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Receptor binding affinity was determined against [125I]ET1 with membranes prepared from human placenta for ETB receptor | Bioorg Med Chem Lett 7: 2223-2228 (1997) Article DOI: 10.1016/S0960-894X(97)00400-9 BindingDB Entry DOI: 10.7270/Q2WQ049M | |||||||||||
More data for this Ligand-Target Pair |