Compile Data Set for Download or QSAR

Found 69 hits Enz. Inhib. hit(s) with all data for entry = 50036007   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006490 ((+)-(7-Chloro-6-fluoro-4-hydroxy-2-methyl-chroman-...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(F)c(Cl)cc2O1 Show InChI InChI=1S/C12H12ClFO4/c1-6-4-12(17,5-11(15)16)7-2-9(14)8(13)3-10(7)18-6/h2-3,6,17H,4-5H2,1H3,(H,15,16)/t6-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Compound was tested in vitro for its inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006490 ((+)-(7-Chloro-6-fluoro-4-hydroxy-2-methyl-chroman-...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(F)c(Cl)cc2O1 Show InChI InChI=1S/C12H12ClFO4/c1-6-4-12(17,5-11(15)16)7-2-9(14)8(13)3-10(7)18-6/h2-3,6,17H,4-5H2,1H3,(H,15,16)/t6-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Compound was tested in vitro for its inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006490 ((+)-(7-Chloro-6-fluoro-4-hydroxy-2-methyl-chroman-...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(F)c(Cl)cc2O1 Show InChI InChI=1S/C12H12ClFO4/c1-6-4-12(17,5-11(15)16)7-2-9(14)8(13)3-10(7)18-6/h2-3,6,17H,4-5H2,1H3,(H,15,16)/t6-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006496 ((7-Bromo-6-chloro-4-hydroxy-2-methyl-chroman-4-yl)...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(Cl)c(Br)cc2O1 Show InChI InChI=1S/C12H12BrClO4/c1-6-4-12(17,5-11(15)16)7-2-9(14)8(13)3-10(7)18-6/h2-3,6,17H,4-5H2,1H3,(H,15,16)/t6-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Compound was tested in vitro for its inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006500 ((7-Benzyloxy-6-chloro-4-hydroxy-2-methyl-chroman-4...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(Cl)c(OCc3ccccc3)cc2O1 Show InChI InChI=1S/C19H19ClO5/c1-12-9-19(23,10-18(21)22)14-7-15(20)17(8-16(14)25-12)24-11-13-5-3-2-4-6-13/h2-8,12,23H,9-11H2,1H3,(H,21,22)/t12-,19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006490 ((+)-(7-Chloro-6-fluoro-4-hydroxy-2-methyl-chroman-...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(F)c(Cl)cc2O1 Show InChI InChI=1S/C12H12ClFO4/c1-6-4-12(17,5-11(15)16)7-2-9(14)8(13)3-10(7)18-6/h2-3,6,17H,4-5H2,1H3,(H,15,16)/t6-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006496 ((7-Bromo-6-chloro-4-hydroxy-2-methyl-chroman-4-yl)...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(Cl)c(Br)cc2O1 Show InChI InChI=1S/C12H12BrClO4/c1-6-4-12(17,5-11(15)16)7-2-9(14)8(13)3-10(7)18-6/h2-3,6,17H,4-5H2,1H3,(H,15,16)/t6-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006530 ((7-Fluoro-4-hydroxy-2-methyl-6-nitro-chroman-4-yl)...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(c(F)cc2O1)[N+]([O-])=O Show InChI InChI=1S/C12H12FNO6/c1-6-4-12(17,5-11(15)16)7-2-9(14(18)19)8(13)3-10(7)20-6/h2-3,6,17H,4-5H2,1H3,(H,15,16)/t6-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006493 (4-Carboxymethyl-4-hydroxy-2-methyl-chroman-7-carbo...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2ccc(cc2O1)C(O)=O Show InChI InChI=1S/C13H14O6/c1-7-5-13(18,6-11(14)15)9-3-2-8(12(16)17)4-10(9)19-7/h2-4,7,18H,5-6H2,1H3,(H,14,15)(H,16,17)/t7-,13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006532 ((4-Hydroxy-2-methyl-6-nitro-chroman-4-yl)-acetic a...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(ccc2O1)[N+]([O-])=O Show InChI InChI=1S/C12H13NO6/c1-7-5-12(16,6-11(14)15)9-4-8(13(17)18)2-3-10(9)19-7/h2-4,7,16H,5-6H2,1H3,(H,14,15)/t7-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006507 ((7-Bromo-6-fluoro-4-hydroxy-2-methyl-chroman-4-yl)...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(F)c(Br)cc2O1 Show InChI InChI=1S/C12H12BrFO4/c1-6-4-12(17,5-11(15)16)7-2-9(14)8(13)3-10(7)18-6/h2-3,6,17H,4-5H2,1H3,(H,15,16)/t6-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006533 ((4-Hydroxy-2,7-dimethyl-6-nitro-chroman-4-yl)-acet...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(c(C)cc2O1)[N+]([O-])=O Show InChI InChI=1S/C13H15NO6/c1-7-3-11-9(4-10(7)14(18)19)13(17,6-12(15)16)5-8(2)20-11/h3-4,8,17H,5-6H2,1-2H3,(H,15,16)/t8-,13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006529 ((6-Chloro-7-ethyl-4-hydroxy-2-methyl-chroman-4-yl)...) Show SMILES CCc1cc2O[C@H](C)C[C@@](O)(CC(O)=O)c2cc1Cl Show InChI InChI=1S/C14H17ClO4/c1-3-9-4-12-10(5-11(9)15)14(18,7-13(16)17)6-8(2)19-12/h4-5,8,18H,3,6-7H2,1-2H3,(H,16,17)/t8-,14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006504 ((7-Chloro-4-hydroxy-2-methyl-6-nitro-chroman-4-yl)...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(c(Cl)cc2O1)[N+]([O-])=O Show InChI InChI=1S/C12H12ClNO6/c1-6-4-12(17,5-11(15)16)7-2-9(14(18)19)8(13)3-10(7)20-6/h2-3,6,17H,4-5H2,1H3,(H,15,16)/t6-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006507 ((7-Bromo-6-fluoro-4-hydroxy-2-methyl-chroman-4-yl)...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(F)c(Br)cc2O1 Show InChI InChI=1S/C12H12BrFO4/c1-6-4-12(17,5-11(15)16)7-2-9(14)8(13)3-10(7)18-6/h2-3,6,17H,4-5H2,1H3,(H,15,16)/t6-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Compound was tested in vitro for its inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006509 ((6-Cyano-7-fluoro-4-hydroxy-2-methyl-chroman-4-yl)...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(C#N)c(F)cc2O1 Show InChI InChI=1S/C13H12FNO4/c1-7-4-13(18,5-12(16)17)9-2-8(6-15)10(14)3-11(9)19-7/h2-3,7,18H,4-5H2,1H3,(H,16,17)/t7-,13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006502 ((+)-(6,7-Dichloro-4-hydroxy-2-methyl-chroman-4-yl)...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(Cl)c(Cl)cc2O1 Show InChI InChI=1S/C12H12Cl2O4/c1-6-4-12(17,5-11(15)16)7-2-8(13)9(14)3-10(7)18-6/h2-3,6,17H,4-5H2,1H3,(H,15,16)/t6-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Compound was tested in vitro for its inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006502 ((+)-(6,7-Dichloro-4-hydroxy-2-methyl-chroman-4-yl)...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(Cl)c(Cl)cc2O1 Show InChI InChI=1S/C12H12Cl2O4/c1-6-4-12(17,5-11(15)16)7-2-8(13)9(14)3-10(7)18-6/h2-3,6,17H,4-5H2,1H3,(H,15,16)/t6-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	156	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006502 ((+)-(6,7-Dichloro-4-hydroxy-2-methyl-chroman-4-yl)...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(Cl)c(Cl)cc2O1 Show InChI InChI=1S/C12H12Cl2O4/c1-6-4-12(17,5-11(15)16)7-2-8(13)9(14)3-10(7)18-6/h2-3,6,17H,4-5H2,1H3,(H,15,16)/t6-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006502 ((+)-(6,7-Dichloro-4-hydroxy-2-methyl-chroman-4-yl)...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(Cl)c(Cl)cc2O1 Show InChI InChI=1S/C12H12Cl2O4/c1-6-4-12(17,5-11(15)16)7-2-8(13)9(14)3-10(7)18-6/h2-3,6,17H,4-5H2,1H3,(H,15,16)/t6-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006513 ((6-Chloro-4-hydroxy-7-methoxy-2-methyl-chroman-4-y...) Show SMILES COc1cc2O[C@H](C)C[C@@](O)(CC(O)=O)c2cc1Cl Show InChI InChI=1S/C13H15ClO5/c1-7-5-13(17,6-12(15)16)8-3-9(14)11(18-2)4-10(8)19-7/h3-4,7,17H,5-6H2,1-2H3,(H,15,16)/t7-,13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006506 ((6-Fluoro-4-hydroxy-2-methyl-chroman-4-yl)-acetic ...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(F)ccc2O1 Show InChI InChI=1S/C12H13FO4/c1-7-5-12(16,6-11(14)15)9-4-8(13)2-3-10(9)17-7/h2-4,7,16H,5-6H2,1H3,(H,14,15)/t7-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006524 ((6-Chloro-4-hydroxy-2,7-dimethyl-chroman-4-yl)-ace...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(Cl)c(C)cc2O1 Show InChI InChI=1S/C13H15ClO4/c1-7-3-11-9(4-10(7)14)13(17,6-12(15)16)5-8(2)18-11/h3-4,8,17H,5-6H2,1-2H3,(H,15,16)/t8-,13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006498 ((6,7-Difluoro-4-hydroxy-2-methyl-chroman-4-yl)-ace...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(F)c(F)cc2O1 Show InChI InChI=1S/C12H12F2O4/c1-6-4-12(17,5-11(15)16)7-2-8(13)9(14)3-10(7)18-6/h2-3,6,17H,4-5H2,1H3,(H,15,16)/t6-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006506 ((6-Fluoro-4-hydroxy-2-methyl-chroman-4-yl)-acetic ...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(F)ccc2O1 Show InChI InChI=1S/C12H13FO4/c1-7-5-12(16,6-11(14)15)9-4-8(13)2-3-10(9)17-7/h2-4,7,16H,5-6H2,1H3,(H,14,15)/t7-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Compound was tested in vitro for its inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006498 ((6,7-Difluoro-4-hydroxy-2-methyl-chroman-4-yl)-ace...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(F)c(F)cc2O1 Show InChI InChI=1S/C12H12F2O4/c1-6-4-12(17,5-11(15)16)7-2-8(13)9(14)3-10(7)18-6/h2-3,6,17H,4-5H2,1H3,(H,15,16)/t6-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Compound was tested in vitro for its inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006508 ((2-tert-Butyl-6-fluoro-4-hydroxy-chroman-4-yl)-ace...) Show SMILES CC(C)(C)[C@@H]1C[C@@](O)(CC(O)=O)c2cc(F)ccc2O1 Show InChI InChI=1S/C15H19FO4/c1-14(2,3)12-7-15(19,8-13(17)18)10-6-9(16)4-5-11(10)20-12/h4-6,12,19H,7-8H2,1-3H3,(H,17,18)/t12-,15+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006519 ((6-Chloro-7-fluoro-4-hydroxy-2-methyl-chroman-4-yl...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(Cl)c(F)cc2O1 Show InChI InChI=1S/C12H12ClFO4/c1-6-4-12(17,5-11(15)16)7-2-8(13)9(14)3-10(7)18-6/h2-3,6,17H,4-5H2,1H3,(H,15,16)/t6-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006534 ((4-Hydroxy-2,2-dimethyl-6-nitro-chroman-4-yl)-acet...) Show SMILES CC1(C)C[C@@](O)(CC(O)=O)c2cc(ccc2O1)[N+]([O-])=O Show InChI InChI=1S/C13H15NO6/c1-12(2)7-13(17,6-11(15)16)9-5-8(14(18)19)3-4-10(9)20-12/h3-5,17H,6-7H2,1-2H3,(H,15,16)/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006535 ((6-Chloro-4-hydroxy-2-methyl-3,4-dihydro-2H-benzo[...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(Cl)c3ccccc3c2O1 Show InChI InChI=1S/C16H15ClO4/c1-9-7-16(20,8-14(18)19)12-6-13(17)10-4-2-3-5-11(10)15(12)21-9/h2-6,9,20H,7-8H2,1H3,(H,18,19)/t9-,16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006519 ((6-Chloro-7-fluoro-4-hydroxy-2-methyl-chroman-4-yl...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(Cl)c(F)cc2O1 Show InChI InChI=1S/C12H12ClFO4/c1-6-4-12(17,5-11(15)16)7-2-8(13)9(14)3-10(7)18-6/h2-3,6,17H,4-5H2,1H3,(H,15,16)/t6-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Compound was tested in vitro for its inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006503 ((6-Fluoro-4-hydroxy-2-isopropyl-chroman-4-yl)-acet...) Show SMILES CC(C)[C@@H]1C[C@@](O)(CC(O)=O)c2cc(F)ccc2O1 Show InChI InChI=1S/C14H17FO4/c1-8(2)12-6-14(18,7-13(16)17)10-5-9(15)3-4-11(10)19-12/h3-5,8,12,18H,6-7H2,1-2H3,(H,16,17)/t12-,14+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006523 ((6-Fluoro-4-hydroxy-chroman-4-yl)-acetic acid | CH...) Show SMILES OC(=O)C[C@]1(O)CCOc2ccc(F)cc12 Show InChI InChI=1S/C11H11FO4/c12-7-1-2-9-8(5-7)11(15,3-4-16-9)6-10(13)14/h1-2,5,15H,3-4,6H2,(H,13,14)/t11-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006488 ((2-Ethyl-6-fluoro-4-hydroxy-chroman-4-yl)-acetic a...) Show SMILES CC[C@@H]1C[C@@](O)(CC(O)=O)c2cc(F)ccc2O1 Show InChI InChI=1S/C13H15FO4/c1-2-9-6-13(17,7-12(15)16)10-5-8(14)3-4-11(10)18-9/h3-5,9,17H,2,6-7H2,1H3,(H,15,16)/t9-,13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006536 ((6-Acetyl-4-hydroxy-2-methyl-chroman-4-yl)-acetic ...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(ccc2O1)C(C)=O Show InChI InChI=1S/C14H16O5/c1-8-6-14(18,7-13(16)17)11-5-10(9(2)15)3-4-12(11)19-8/h3-5,8,18H,6-7H2,1-2H3,(H,16,17)/t8-,14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006510 ((7,8-Dichloro-4-hydroxy-2-methyl-chroman-4-yl)-ace...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2ccc(Cl)c(Cl)c2O1 Show InChI InChI=1S/C12H12Cl2O4/c1-6-4-12(17,5-9(15)16)7-2-3-8(13)10(14)11(7)18-6/h2-3,6,17H,4-5H2,1H3,(H,15,16)/t6-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006512 ((6-Chloro-4-hydroxy-2-methyl-chroman-4-yl)-acetic ...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(Cl)ccc2O1 Show InChI InChI=1S/C12H13ClO4/c1-7-5-12(16,6-11(14)15)9-4-8(13)2-3-10(9)17-7/h2-4,7,16H,5-6H2,1H3,(H,14,15)/t7-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006538 ((6-Fluoro-4-hydroxy-2,3-dimethyl-chroman-4-yl)-ace...) Show SMILES C[C@H]1Oc2ccc(F)cc2[C@](O)(CC(O)=O)[C@H]1C Show InChI InChI=1S/C13H15FO4/c1-7-8(2)18-11-4-3-9(14)5-10(11)13(7,17)6-12(15)16/h3-5,7-8,17H,6H2,1-2H3,(H,15,16)/t7-,8+,13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006491 ((6-Fluoro-4-hydroxy-2-propyl-chroman-4-yl)-acetic ...) Show SMILES CCC[C@@H]1C[C@@](O)(CC(O)=O)c2cc(F)ccc2O1 Show InChI InChI=1S/C14H17FO4/c1-2-3-10-7-14(18,8-13(16)17)11-6-9(15)4-5-12(11)19-10/h4-6,10,18H,2-3,7-8H2,1H3,(H,16,17)/t10-,14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	970	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006521 ((6,8-Dichloro-4-hydroxy-2-methyl-chroman-4-yl)-ace...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(Cl)cc(Cl)c2O1 Show InChI InChI=1S/C12H12Cl2O4/c1-6-4-12(17,5-10(15)16)8-2-7(13)3-9(14)11(8)18-6/h2-3,6,17H,4-5H2,1H3,(H,15,16)/t6-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006499 ((6-Fluoro-4-hydroxy-2-phenethyl-chroman-4-yl)-acet...) Show SMILES OC(=O)C[C@]1(O)C[C@@H](CCc2ccccc2)Oc2ccc(F)cc12 Show InChI InChI=1S/C19H19FO4/c20-14-7-9-17-16(10-14)19(23,12-18(21)22)11-15(24-17)8-6-13-4-2-1-3-5-13/h1-5,7,9-10,15,23H,6,8,11-12H2,(H,21,22)/t15-,19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006511 ((6-Chloro-4-hydroxy-2,8-dimethyl-chroman-4-yl)-ace...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(Cl)cc(C)c2O1 Show InChI InChI=1S/C13H15ClO4/c1-7-3-9(14)4-10-12(7)18-8(2)5-13(10,17)6-11(15)16/h3-4,8,17H,5-6H2,1-2H3,(H,15,16)/t8-,13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50368324 (CHEMBL1744091) Show SMILES OC(=O)C[C@]1(O)C[C@H](Oc2ccc(F)cc12)C(=O)c1ccccc1 |r| Show InChI InChI=1S/C18H15FO5/c19-12-6-7-14-13(8-12)18(23,10-16(20)21)9-15(24-14)17(22)11-4-2-1-3-5-11/h1-8,15,23H,9-10H2,(H,20,21)/t15-,18+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006492 ((4-Hydroxy-2,5-dimethyl-5-nitro-3,4,5,6-tetrahydro...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)C2=C(O1)C=CCC2(C)[N+]([O-])=O |c:9,13| Show InChI InChI=1S/C13H17NO6/c1-8-6-13(17,7-10(15)16)11-9(20-8)4-3-5-12(11,2)14(18)19/h3-4,8,17H,5-7H2,1-2H3,(H,15,16)/t8-,12?,13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006520 ((5,6-Dichloro-4-hydroxy-2-methyl-chroman-4-yl)-ace...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2c(Cl)c(Cl)ccc2O1 Show InChI InChI=1S/C12H12Cl2O4/c1-6-4-12(17,5-9(15)16)10-8(18-6)3-2-7(13)11(10)14/h2-3,6,17H,4-5H2,1H3,(H,15,16)/t6-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006531 ((6-Bromo-4-hydroxy-2-methyl-chroman-4-yl)-acetic a...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2cc(Br)ccc2O1 Show InChI InChI=1S/C12H13BrO4/c1-7-5-12(16,6-11(14)15)9-4-8(13)2-3-10(9)17-7/h2-4,7,16H,5-6H2,1H3,(H,14,15)/t7-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006527 ((6,7-Dichloro-4-hydroxy-2,2-dimethyl-chroman-4-yl)...) Show SMILES CC1(C)C[C@@](O)(CC(O)=O)c2cc(Cl)c(Cl)cc2O1 Show InChI InChI=1S/C13H14Cl2O4/c1-12(2)6-13(18,5-11(16)17)7-3-8(14)9(15)4-10(7)19-12/h3-4,18H,5-6H2,1-2H3,(H,16,17)/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006517 ((7-Fluoro-9-hydroxy-1,2,3,3a,9,9a-hexahydro-cyclop...) Show SMILES OC(=O)C[C@]1(O)[C@H]2CCC[C@H]2Oc2ccc(F)cc12 Show InChI InChI=1S/C14H15FO4/c15-8-4-5-12-10(6-8)14(18,7-13(16)17)9-2-1-3-11(9)19-12/h4-6,9,11,18H,1-3,7H2,(H,16,17)/t9-,11+,14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006540 ((6-Fluoro-4-hydroxy-2-phenyl-chroman-4-yl)-acetic ...) Show SMILES OC(=O)C[C@]1(O)C[C@H](Oc2ccc(F)cc12)c1ccccc1 Show InChI InChI=1S/C17H15FO4/c18-12-6-7-14-13(8-12)17(21,10-16(19)20)9-15(22-14)11-4-2-1-3-5-11/h1-8,15,21H,9-10H2,(H,19,20)/t15-,17+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006514 ((7-Chloro-4-hydroxy-2-methyl-chroman-4-yl)-acetic ...) Show SMILES C[C@@H]1C[C@@](O)(CC(O)=O)c2ccc(Cl)cc2O1 Show InChI InChI=1S/C12H13ClO4/c1-7-5-12(16,6-11(14)15)9-3-2-8(13)4-10(9)17-7/h2-4,7,16H,5-6H2,1H3,(H,14,15)/t7-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair

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