BindingDB PrimarySearch

Found 9 hits Enz. Inhib. hit(s) with all data for entry = 50037618
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Aromatase (Homo sapiens (Human))	BDBM50174541 ((3R,4S,5R,10R,13S)-10,13-Dimethyl-hexadecahydro-20...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Oporto Curated by ChEMBL					Assay Description Inhibition constant against aromatase protein from human placental microsomes using [1-beta-3H]-androstenedione; Competitive inhibition				J Med Chem 48: 6379-85 (2005) Article DOI: 10.1021/jm050129p BindingDB Entry DOI: 10.7270/Q25M66GD
University of Oporto Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50174544 ((5S,10S,13S)-10,13-Dimethyl-1,2,5,6,7,8,9,10,11,12...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Oporto Curated by ChEMBL					Assay Description Inhibition constant against aromatase protein from human placental microsomes using [1-beta-3H]-androstenedione; Competitive inhibition				J Med Chem 48: 6379-85 (2005) Article DOI: 10.1021/jm050129p BindingDB Entry DOI: 10.7270/Q25M66GD
University of Oporto Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50174543 ((3R,5R,10R,13S)-3-Hydroxy-10,13-dimethyl-tetradeca...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	147	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Oporto Curated by ChEMBL					Assay Description Inhibition constant against aromatase protein from human placental microsomes using [1-beta-3H]-androstenedione; Competitive inhibition				J Med Chem 48: 6379-85 (2005) Article DOI: 10.1021/jm050129p BindingDB Entry DOI: 10.7270/Q25M66GD
University of Oporto Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50174542 ((10aR,12aS)-7-Hydroxy-10a,12a-dimethyl-3,4,4a,5,6,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Oporto Curated by ChEMBL					Assay Description Inhibition constant against aromatase protein from human placental microsomes using [1-beta-3H]-androstenedione; Competitive inhibition				J Med Chem 48: 6379-85 (2005) Article DOI: 10.1021/jm050129p BindingDB Entry DOI: 10.7270/Q25M66GD
University of Oporto Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50240798 ((8R,9S,10R,13S,14S)-4-Hydroxy-10,13-dimethyl-1,6,7...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
University of Oporto Curated by ChEMBL					Assay Description Inhibitory concentration against aromatase protein from human placental microsomes using [1-beta-3H]-androstenedione; Competitive inhibition				J Med Chem 48: 6379-85 (2005) Article DOI: 10.1021/jm050129p BindingDB Entry DOI: 10.7270/Q25M66GD
University of Oporto Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50174541 ((3R,4S,5R,10R,13S)-10,13-Dimethyl-hexadecahydro-20...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	145	n/a	n/a	n/a	n/a	n/a	n/a
University of Oporto Curated by ChEMBL					Assay Description Inhibitory concentration against aromatase protein from human placental microsomes using [1-beta-3H]-androstenedione; Competitive inhibition				J Med Chem 48: 6379-85 (2005) Article DOI: 10.1021/jm050129p BindingDB Entry DOI: 10.7270/Q25M66GD
University of Oporto Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50174544 ((5S,10S,13S)-10,13-Dimethyl-1,2,5,6,7,8,9,10,11,12...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	225	n/a	n/a	n/a	n/a	n/a	n/a
University of Oporto Curated by ChEMBL					Assay Description Inhibitory concentration against aromatase protein from human placental microsomes using [1-beta-3H]-androstenedione; Competitive inhibition				J Med Chem 48: 6379-85 (2005) Article DOI: 10.1021/jm050129p BindingDB Entry DOI: 10.7270/Q25M66GD
University of Oporto Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50174543 ((3R,5R,10R,13S)-3-Hydroxy-10,13-dimethyl-tetradeca...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
University of Oporto Curated by ChEMBL					Assay Description Inhibitory concentration against aromatase protein from human placental microsomes using [1-beta-3H]-androstenedione; Competitive inhibition				J Med Chem 48: 6379-85 (2005) Article DOI: 10.1021/jm050129p BindingDB Entry DOI: 10.7270/Q25M66GD
University of Oporto Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50174542 ((10aR,12aS)-7-Hydroxy-10a,12a-dimethyl-3,4,4a,5,6,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oporto Curated by ChEMBL					Assay Description Inhibitory concentration against aromatase protein from human placental microsomes using [1-beta-3H]-androstenedione; Competitive inhibition				J Med Chem 48: 6379-85 (2005) Article DOI: 10.1021/jm050129p BindingDB Entry DOI: 10.7270/Q25M66GD
University of Oporto Curated by ChEMBL					More data for this Ligand-Target Pair