Found 279 hits Enz. Inhib. hit(s) with all data for entry = 50037671 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50182573
(1-(3,4-dichlorophenyl)-2-pyrrolidin-1-yl-pentan-1-...)Show InChI InChI=1S/C15H19Cl2NO/c1-2-5-14(18-8-3-4-9-18)15(19)11-6-7-12(16)13(17)10-11/h6-7,10,14H,2-5,8-9H2,1H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 11.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50182565
(4-methyl-2-pyrrolidin-1-yl-1-(4-methylphenyl)penta...)Show InChI InChI=1S/C17H25NO/c1-13(2)12-16(18-10-4-5-11-18)17(19)15-8-6-14(3)7-9-15/h6-9,13,16H,4-5,10-12H2,1-3H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 13.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50182560
((1S)-1-(4-methylphenyl)-2-pyrrolidin-1-yl-pentan-1...)Show InChI InChI=1S/C16H23NO/c1-3-6-15(17-11-4-5-12-17)16(18)14-9-7-13(2)8-10-14/h7-10,15H,3-6,11-12H2,1-2H3/t15-/m0/s1 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 18.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50182546
(1-naphthalen-2-yl-2-pyrrolidin-1-yl-pentan-1-one |...)Show InChI InChI=1S/C19H23NO/c1-2-7-18(20-12-5-6-13-20)19(21)17-11-10-15-8-3-4-9-16(15)14-17/h3-4,8-11,14,18H,2,5-7,12-13H2,1H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 20.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50182555
(1-(4-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one ...)Show InChI InChI=1S/C16H23NO/c1-3-6-15(17-11-4-5-12-17)16(18)14-9-7-13(2)8-10-14/h7-10,15H,3-6,11-12H2,1-2H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 21.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50182562
(1-(3,4-dichlorophenyl)-2-pyrrolidin-1-yl-butan-1-o...)Show InChI InChI=1S/C14H17Cl2NO/c1-2-13(17-7-3-4-8-17)14(18)10-5-6-11(15)12(16)9-10/h5-6,9,13H,2-4,7-8H2,1H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 28.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50182579
(CHEMBL379679 | N-[4-(2-pyrrolidin-1-yl-pentanoyl)p...)Show InChI InChI=1S/C17H24N2O2/c1-3-6-16(19-11-4-5-12-19)17(21)14-7-9-15(10-8-14)18-13(2)20/h7-10,16H,3-6,11-12H2,1-2H3,(H,18,20) | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 30.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50182546
(1-naphthalen-2-yl-2-pyrrolidin-1-yl-pentan-1-one |...)Show InChI InChI=1S/C19H23NO/c1-2-7-18(20-12-5-6-13-20)19(21)17-11-10-15-8-3-4-9-16(15)14-17/h3-4,8-11,14,18H,2,5-7,12-13H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 33.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50182584
(2pyrrolidin-1-yl-1-phenylpentan-1-one | CHEMBL2050...)Show InChI InChI=1S/C15H21NO/c1-2-8-14(16-11-6-7-12-16)15(17)13-9-4-3-5-10-13/h3-5,9-10,14H,2,6-8,11-12H2,1H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 33.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50182573
(1-(3,4-dichlorophenyl)-2-pyrrolidin-1-yl-pentan-1-...)Show InChI InChI=1S/C15H19Cl2NO/c1-2-5-14(18-8-3-4-9-18)15(19)11-6-7-12(16)13(17)10-11/h6-7,10,14H,2-5,8-9H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 37.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human NET expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50182564
(1-(3,4-dichlorophenyl)-2-pyrrolidin-1-yl-pent-4-en...)Show InChI InChI=1S/C15H17Cl2NO/c1-2-5-14(18-8-3-4-9-18)15(19)11-6-7-12(16)13(17)10-11/h2,6-7,10,14H,1,3-5,8-9H2 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 39.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50182567
(1-(4-hydroxymethylphenyl)-2-pyrrolidin-1-yl-pentan...)Show InChI InChI=1S/C16H23NO2/c1-2-5-15(17-10-3-4-11-17)16(19)14-8-6-13(12-18)7-9-14/h6-9,15,18H,2-5,10-12H2,1H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 48.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50182578
(1-(4-bromophenyl)-2-pyrrolidin-1-yl-pentan-1-one |...)Show InChI InChI=1S/C15H20BrNO/c1-2-5-14(17-10-3-4-11-17)15(18)12-6-8-13(16)9-7-12/h6-9,14H,2-5,10-11H2,1H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50182548
(1-(3-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one ...)Show InChI InChI=1S/C16H23NO/c1-3-7-15(17-10-4-5-11-17)16(18)14-9-6-8-13(2)12-14/h6,8-9,12,15H,3-5,7,10-11H2,1-2H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50182551
(1-(2-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one ...)Show InChI InChI=1S/C16H23NO/c1-3-8-15(17-11-6-7-12-17)16(18)14-10-5-4-9-13(14)2/h4-5,9-10,15H,3,6-8,11-12H2,1-2H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 59.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50182575
(1-(4-propynylphenyl)-2-pyrrolidin-1-yl-pentan-1-on...)Show InChI InChI=1S/C18H23NO/c1-3-7-15-9-11-16(12-10-15)18(20)17(8-4-2)19-13-5-6-14-19/h9-12,17H,4-6,8,13-14H2,1-2H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 61 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50182575
(1-(4-propynylphenyl)-2-pyrrolidin-1-yl-pentan-1-on...)Show InChI InChI=1S/C18H23NO/c1-3-7-15-9-11-16(12-10-15)18(20)17(8-4-2)19-13-5-6-14-19/h9-12,17H,4-6,8,13-14H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 69.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human NET expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50182577
(1-(4-iodophenyl)-2-pyrrolidin-1-yl-pentan-1-one | ...)Show InChI InChI=1S/C15H20INO/c1-2-5-14(17-10-3-4-11-17)15(18)12-6-8-13(16)9-7-12/h6-9,14H,2-5,10-11H2,1H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 81.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50182583
(1-(4-fluorophenyl)-2-pyrrolidin-1-yl-pentan-1-one ...)Show InChI InChI=1S/C15H20FNO/c1-2-5-14(17-10-3-4-11-17)15(18)12-6-8-13(16)9-7-12/h6-9,14H,2-5,10-11H2,1H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 82 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50182559
(1-(3,4-dihydroxyphenyl)-2-pyrrolidin-1-yl-pentan-1...)Show InChI InChI=1S/C15H21NO3/c1-2-5-12(16-8-3-4-9-16)15(19)11-6-7-13(17)14(18)10-11/h6-7,10,12,17-18H,2-5,8-9H2,1H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 84 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50182572
(1-(4-methylphenyl)-2-pyrrolidin-1-yl-pent-4-ene-1-...)Show InChI InChI=1S/C16H21NO/c1-3-6-15(17-11-4-5-12-17)16(18)14-9-7-13(2)8-10-14/h3,7-10,15H,1,4-6,11-12H2,2H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 90.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50182574
(1-(4-furan-2-ylphenyl)-2-pyrrolidin-1-yl-pentan-1-...)Show InChI InChI=1S/C19H23NO2/c1-2-6-17(20-12-3-4-13-20)19(21)16-10-8-15(9-11-16)18-7-5-14-22-18/h5,7-11,14,17H,2-4,6,12-13H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 95 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human NET expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50182574
(1-(4-furan-2-ylphenyl)-2-pyrrolidin-1-yl-pentan-1-...)Show InChI InChI=1S/C19H23NO2/c1-2-6-17(20-12-3-4-13-20)19(21)16-10-8-15(9-11-16)18-7-5-14-22-18/h5,7-11,14,17H,2-4,6,12-13H2,1H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 105 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50182560
((1S)-1-(4-methylphenyl)-2-pyrrolidin-1-yl-pentan-1...)Show InChI InChI=1S/C16H23NO/c1-3-6-15(17-11-4-5-12-17)16(18)14-9-7-13(2)8-10-14/h7-10,15H,3-6,11-12H2,1-2H3/t15-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 109 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human NET expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50182570
(1-(3-iodophenyl)-2-pyrrolidin-1-yl-pentan-1-one | ...)Show InChI InChI=1S/C15H20INO/c1-2-6-14(17-9-3-4-10-17)15(18)12-7-5-8-13(16)11-12/h5,7-8,11,14H,2-4,6,9-10H2,1H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 109 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50182549
(1-(4-hydroxyphenyl)-2-pyrrolidin-1-yl-pentan-1-one...)Show InChI InChI=1S/C15H21NO2/c1-2-5-14(16-10-3-4-11-16)15(18)12-6-8-13(17)9-7-12/h6-9,14,17H,2-5,10-11H2,1H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 125 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50182546
(1-naphthalen-2-yl-2-pyrrolidin-1-yl-pentan-1-one |...)Show InChI InChI=1S/C19H23NO/c1-2-7-18(20-12-5-6-13-20)19(21)17-11-10-15-8-3-4-9-16(15)14-17/h3-4,8-11,14,18H,2,5-7,12-13H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 136 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human NET expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50182557
(1-(3,4-dichlorophenyl)-2-piperidin-1-yl-pentan-1-o...)Show InChI InChI=1S/C16H21Cl2NO/c1-2-6-15(19-9-4-3-5-10-19)16(20)12-7-8-13(17)14(18)11-12/h7-8,11,15H,2-6,9-10H2,1H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 144 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50182567
(1-(4-hydroxymethylphenyl)-2-pyrrolidin-1-yl-pentan...)Show InChI InChI=1S/C16H23NO2/c1-2-5-15(17-10-3-4-11-17)16(19)14-8-6-13(12-18)7-9-14/h6-9,15,18H,2-5,10-12H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human NET expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50182555
(1-(4-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one ...)Show InChI InChI=1S/C16H23NO/c1-3-6-15(17-11-4-5-12-17)16(18)14-9-7-13(2)8-10-14/h7-10,15H,3-6,11-12H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 195 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human NET expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50182573
(1-(3,4-dichlorophenyl)-2-pyrrolidin-1-yl-pentan-1-...)Show InChI InChI=1S/C15H19Cl2NO/c1-2-5-14(18-8-3-4-9-18)15(19)11-6-7-12(16)13(17)10-11/h6-7,10,14H,2-5,8-9H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 199 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50182584
(2pyrrolidin-1-yl-1-phenylpentan-1-one | CHEMBL2050...)Show InChI InChI=1S/C15H21NO/c1-2-8-14(16-11-6-7-12-16)15(17)13-9-4-3-5-10-13/h3-5,9-10,14H,2,6-8,11-12H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 199 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human NET expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50182548
(1-(3-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one ...)Show InChI InChI=1S/C16H23NO/c1-3-7-15(17-10-4-5-11-17)16(18)14-9-6-8-13(2)12-14/h6,8-9,12,15H,3-5,7,10-11H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 216 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human NET expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50182559
(1-(3,4-dihydroxyphenyl)-2-pyrrolidin-1-yl-pentan-1...)Show InChI InChI=1S/C15H21NO3/c1-2-5-12(16-8-3-4-9-16)15(19)11-6-7-13(17)14(18)10-11/h6-7,10,12,17-18H,2-5,8-9H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 219 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human NET expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50182565
(4-methyl-2-pyrrolidin-1-yl-1-(4-methylphenyl)penta...)Show InChI InChI=1S/C17H25NO/c1-13(2)12-16(18-10-4-5-11-18)17(19)15-8-6-14(3)7-9-15/h6-9,13,16H,4-5,10-12H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 259 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human NET expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50182562
(1-(3,4-dichlorophenyl)-2-pyrrolidin-1-yl-butan-1-o...)Show InChI InChI=1S/C14H17Cl2NO/c1-2-13(17-7-3-4-8-17)14(18)10-5-6-11(15)12(16)9-10/h5-6,9,13H,2-4,7-8H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 262 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human NET expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50182563
(1-(4-nitrophenyl)-2-pyrrolidin-1-yl-pentan-1-one |...)Show InChI InChI=1S/C15H20N2O3/c1-2-5-14(16-10-3-4-11-16)15(18)12-6-8-13(9-7-12)17(19)20/h6-9,14H,2-5,10-11H2,1H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 266 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50182577
(1-(4-iodophenyl)-2-pyrrolidin-1-yl-pentan-1-one | ...)Show InChI InChI=1S/C15H20INO/c1-2-5-14(17-10-3-4-11-17)15(18)12-6-8-13(16)9-7-12/h6-9,14H,2-5,10-11H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 301 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50182577
(1-(4-iodophenyl)-2-pyrrolidin-1-yl-pentan-1-one | ...)Show InChI InChI=1S/C15H20INO/c1-2-5-14(17-10-3-4-11-17)15(18)12-6-8-13(16)9-7-12/h6-9,14H,2-5,10-11H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 310 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human NET expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50182569
(1-(4-methoxyphenyl)-2-pyrrolidin-1-yl-pentan-1-one...)Show InChI InChI=1S/C16H23NO2/c1-3-6-15(17-11-4-5-12-17)16(18)13-7-9-14(19-2)10-8-13/h7-10,15H,3-6,11-12H2,1-2H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 329 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50084717
((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)Show SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1C(=O)Oc1ccccc1)N2C |THB:2:4:20:6.7| Show InChI InChI=1S/C17H21NO4/c1-18-11-8-9-14(18)15(17(20)21-2)13(10-11)16(19)22-12-6-4-3-5-7-12/h3-7,11,13-15H,8-10H2,1-2H3/t11?,13-,14?,15-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 358 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50182547
(4-(2-pyrrolidin-1-yl-pentanoyl)benzoic acid methyl...)Show InChI InChI=1S/C17H23NO3/c1-3-6-15(18-11-4-5-12-18)16(19)13-7-9-14(10-8-13)17(20)21-2/h7-10,15H,3-6,11-12H2,1-2H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50182571
(2-pyrrolidin-1-yl-1-(4-thiophen-2-yl-phenyl)pentan...)Show InChI InChI=1S/C19H23NOS/c1-2-6-17(20-12-3-4-13-20)19(21)16-10-8-15(9-11-16)18-7-5-14-22-18/h5,7-11,14,17H,2-4,6,12-13H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 370 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human NET expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50182578
(1-(4-bromophenyl)-2-pyrrolidin-1-yl-pentan-1-one |...)Show InChI InChI=1S/C15H20BrNO/c1-2-5-14(17-10-3-4-11-17)15(18)12-6-8-13(16)9-7-12/h6-9,14H,2-5,10-11H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 386 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human NET expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50182551
(1-(2-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one ...)Show InChI InChI=1S/C16H23NO/c1-3-8-15(17-11-6-7-12-17)16(18)14-10-5-4-9-13(14)2/h4-5,9-10,15H,3,6-8,11-12H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 425 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human NET expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50084717
((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)Show SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1C(=O)Oc1ccccc1)N2C |THB:2:4:20:6.7| Show InChI InChI=1S/C17H21NO4/c1-18-11-8-9-14(18)15(17(20)21-2)13(10-11)16(19)22-12-6-4-3-5-7-12/h3-7,11,13-15H,8-10H2,1-2H3/t11?,13-,14?,15-/m0/s1 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 432 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50182571
(2-pyrrolidin-1-yl-1-(4-thiophen-2-yl-phenyl)pentan...)Show InChI InChI=1S/C19H23NOS/c1-2-6-17(20-12-3-4-13-20)19(21)16-10-8-15(9-11-16)18-7-5-14-22-18/h5,7-11,14,17H,2-4,6,12-13H2,1H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50182564
(1-(3,4-dichlorophenyl)-2-pyrrolidin-1-yl-pent-4-en...)Show InChI InChI=1S/C15H17Cl2NO/c1-2-5-14(18-8-3-4-9-18)15(19)11-6-7-12(16)13(17)10-11/h2,6-7,10,14H,1,3-5,8-9H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 509 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human NET expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50182581
(2-butylamin-1-yl-1-(3,4-dichlorophenyl)pentan-1-on...)Show InChI InChI=1S/C15H21Cl2NO/c1-3-5-9-18-14(6-4-2)15(19)11-7-8-12(16)13(17)10-11/h7-8,10,14,18H,3-6,9H2,1-2H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 520 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50182582
(1-(3,4-dichlorophenyl)-2-pyrrolidin-1-yl-methylpen...)Show InChI InChI=1S/C16H21Cl2NO/c1-2-5-13(11-19-8-3-4-9-19)16(20)12-6-7-14(17)15(18)10-12/h6-7,10,13H,2-5,8-9,11H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 630 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Organix Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cells |
J Med Chem 49: 1420-32 (2006)
Article DOI: 10.1021/jm050797a BindingDB Entry DOI: 10.7270/Q2KK9CKB |
More data for this Ligand-Target Pair | |