Found 45 hits Enz. Inhib. hit(s) with all data for entry = 50038442 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cathepsin K
(Homo sapiens (Human)) | BDBM50376511
(CHEMBL261511)Show InChI InChI=1S/C22H25N5/c1-22(2,3)16-25-21-18(14-24-20(13-23)26-21)9-6-11-27-12-10-17-7-4-5-8-19(17)15-27/h4-5,7-8,14H,10-12,15-16H2,1-3H3,(H,24,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin K by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50376500
(CHEMBL261700)Show SMILES CC(C)(C)CN(Cc1ccc(cc1)C#CCN1CCC(CC1)N1CCCCC1)c1ccnc(n1)C#N Show InChI InChI=1S/C30H40N6/c1-30(2,3)24-36(29-13-16-32-28(22-31)33-29)23-26-11-9-25(10-12-26)8-7-17-34-20-14-27(15-21-34)35-18-5-4-6-19-35/h9-13,16,27H,4-6,14-15,17-21,23-24H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin K by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50376507
(CHEMBL429147)Show SMILES CC(C)(C)CNc1nc(ncc1C#CCN1CCN(CC1)S(=O)(=O)CCCCl)C#N Show InChI InChI=1S/C20H29ClN6O2S/c1-20(2,3)16-24-19-17(15-23-18(14-22)25-19)6-4-8-26-9-11-27(12-10-26)30(28,29)13-5-7-21/h15H,5,7-13,16H2,1-3H3,(H,23,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin K by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50376503
(CHEMBL261516)Show SMILES CN1CCN(CC#Cc2ccc(CN(CC(C)(C)C)c3ccnc(n3)C#N)cc2)CC1 Show InChI InChI=1S/C25H32N6/c1-25(2,3)20-31(24-11-12-27-23(18-26)28-24)19-22-9-7-21(8-10-22)6-5-13-30-16-14-29(4)15-17-30/h7-12H,13-17,19-20H2,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin K by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50376504
(CHEMBL258640)Show SMILES CC(C)(C)CN(Cc1ccc(Cn2cncn2)cc1)c1ccnc(n1)C#N Show InChI InChI=1S/C20H23N7/c1-20(2,3)13-26(19-8-9-23-18(10-21)25-19)11-16-4-6-17(7-5-16)12-27-15-22-14-24-27/h4-9,14-15H,11-13H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin K by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50376502
(CHEMBL410520)Show SMILES CC(=O)N1CCN(CC#Cc2ccc(CN(CC(C)(C)C)c3ccnc(n3)C#N)cc2)CC1 Show InChI InChI=1S/C26H32N6O/c1-21(33)31-16-14-30(15-17-31)13-5-6-22-7-9-23(10-8-22)19-32(20-26(2,3)4)25-11-12-28-24(18-27)29-25/h7-12H,13-17,19-20H2,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin K by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50376498
(CHEMBL259939)Show SMILES CN1CCN(CC1)c1ccc(CC#Cc2cnc(nc2NCC(C)(C)C)C#N)cc1 Show InChI InChI=1S/C24H30N6/c1-24(2,3)18-27-23-20(17-26-22(16-25)28-23)7-5-6-19-8-10-21(11-9-19)30-14-12-29(4)13-15-30/h8-11,17H,6,12-15,18H2,1-4H3,(H,26,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 7.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin K by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50376508
(CHEMBL261455)Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC#Cc2cnc(nc2NCC(C)(C)C)C#N)CC1 Show InChI InChI=1S/C24H30N6O3S/c1-24(2,3)18-27-23-19(17-26-22(16-25)28-23)6-5-11-29-12-14-30(15-13-29)34(31,32)21-9-7-20(33-4)8-10-21/h7-10,17H,11-15,18H2,1-4H3,(H,26,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 7.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin K by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50376509
(CHEMBL408562)Show InChI InChI=1S/C16H16Cl2N6/c1-16(2,3)9-21-15-11(8-20-12(7-19)23-15)5-4-6-24-10-22-13(17)14(24)18/h8,10H,6,9H2,1-3H3,(H,20,21,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 7.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin K by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50376501
(CHEMBL408974)Show SMILES CC(C)(C)CN(Cc1ccc(cc1)C#CCN1CCCCC1)c1ccnc(n1)C#N Show InChI InChI=1S/C25H31N5/c1-25(2,3)20-30(24-13-14-27-23(18-26)28-24)19-22-11-9-21(10-12-22)8-7-17-29-15-5-4-6-16-29/h9-14H,4-6,15-17,19-20H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin K by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50376499
(CHEMBL263409)Show SMILES CC(C)(C)CN(Cc1ccc(cc1)C#CCn1cncn1)c1ccnc(n1)C#N Show InChI InChI=1S/C22H23N7/c1-22(2,3)15-28(21-10-11-25-20(13-23)27-21)14-19-8-6-18(7-9-19)5-4-12-29-17-24-16-26-29/h6-11,16-17H,12,14-15H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin K by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50376510
(CHEMBL261673)Show InChI InChI=1S/C18H19N5O/c1-18(2,3)13-22-17-14(11-21-16(10-19)23-17)6-5-9-24-15-7-4-8-20-12-15/h4,7-8,11-12H,9,13H2,1-3H3,(H,21,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin K by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50376512
(CHEMBL261513)Show InChI InChI=1S/C21H23N5/c1-21(2,3)15-24-20-16(12-23-19(11-22)25-20)9-6-10-26-13-17-7-4-5-8-18(17)14-26/h4-5,7-8,12H,10,13-15H2,1-3H3,(H,23,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin K by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50376505
(CHEMBL541991)Show InChI InChI=1S/C17H19IN4/c1-17(2,3)12-22(11-13-4-6-14(18)7-5-13)16-8-9-20-15(10-19)21-16/h4-9H,11-12H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin K by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin S
(Homo sapiens (Human)) | BDBM50376509
(CHEMBL408562)Show InChI InChI=1S/C16H16Cl2N6/c1-16(2,3)9-21-15-11(8-20-12(7-19)23-15)5-4-6-24-10-22-13(17)14(24)18/h8,10H,6,9H2,1-3H3,(H,20,21,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin S by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50376506
(CHEMBL261125)Show InChI InChI=1S/C17H20N4/c1-17(2,3)13-21(12-14-7-5-4-6-8-14)16-9-10-19-15(11-18)20-16/h4-10H,12-13H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin K by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50376511
(CHEMBL261511)Show InChI InChI=1S/C22H25N5/c1-22(2,3)16-25-21-18(14-24-20(13-23)26-21)9-6-11-27-12-10-17-7-4-5-8-19(17)15-27/h4-5,7-8,14H,10-12,15-16H2,1-3H3,(H,24,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin L by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50376509
(CHEMBL408562)Show InChI InChI=1S/C16H16Cl2N6/c1-16(2,3)9-21-15-11(8-20-12(7-19)23-15)5-4-6-24-10-22-13(17)14(24)18/h8,10H,6,9H2,1-3H3,(H,20,21,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin L by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin S
(Homo sapiens (Human)) | BDBM50376510
(CHEMBL261673)Show InChI InChI=1S/C18H19N5O/c1-18(2,3)13-22-17-14(11-21-16(10-19)23-17)6-5-9-24-15-7-4-8-20-12-15/h4,7-8,11-12H,9,13H2,1-3H3,(H,21,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin S by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin S
(Homo sapiens (Human)) | BDBM50376498
(CHEMBL259939)Show SMILES CN1CCN(CC1)c1ccc(CC#Cc2cnc(nc2NCC(C)(C)C)C#N)cc1 Show InChI InChI=1S/C24H30N6/c1-24(2,3)18-27-23-20(17-26-22(16-25)28-23)7-5-6-19-8-10-21(11-9-19)30-14-12-29(4)13-15-30/h8-11,17H,6,12-15,18H2,1-4H3,(H,26,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 760 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin S by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin S
(Homo sapiens (Human)) | BDBM50376507
(CHEMBL429147)Show SMILES CC(C)(C)CNc1nc(ncc1C#CCN1CCN(CC1)S(=O)(=O)CCCCl)C#N Show InChI InChI=1S/C20H29ClN6O2S/c1-20(2,3)16-24-19-17(15-23-18(14-22)25-19)6-4-8-26-9-11-27(12-10-26)30(28,29)13-5-7-21/h15H,5,7-13,16H2,1-3H3,(H,23,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin S by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin S
(Homo sapiens (Human)) | BDBM50376511
(CHEMBL261511)Show InChI InChI=1S/C22H25N5/c1-22(2,3)16-25-21-18(14-24-20(13-23)26-21)9-6-11-27-12-10-17-7-4-5-8-19(17)15-27/h4-5,7-8,14H,10-12,15-16H2,1-3H3,(H,24,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 840 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin S by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin S
(Homo sapiens (Human)) | BDBM50376512
(CHEMBL261513)Show InChI InChI=1S/C21H23N5/c1-21(2,3)15-24-20-16(12-23-19(11-22)25-20)9-6-10-26-13-17-7-4-5-8-18(17)14-26/h4-5,7-8,12H,10,13-15H2,1-3H3,(H,23,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 920 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin S by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50376498
(CHEMBL259939)Show SMILES CN1CCN(CC1)c1ccc(CC#Cc2cnc(nc2NCC(C)(C)C)C#N)cc1 Show InChI InChI=1S/C24H30N6/c1-24(2,3)18-27-23-20(17-26-22(16-25)28-23)7-5-6-19-8-10-21(11-9-19)30-14-12-29(4)13-15-30/h8-11,17H,6,12-15,18H2,1-4H3,(H,26,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 980 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin L by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin S
(Homo sapiens (Human)) | BDBM50376504
(CHEMBL258640)Show SMILES CC(C)(C)CN(Cc1ccc(Cn2cncn2)cc1)c1ccnc(n1)C#N Show InChI InChI=1S/C20H23N7/c1-20(2,3)13-26(19-8-9-23-18(10-21)25-19)11-16-4-6-17(7-5-16)12-27-15-22-14-24-27/h4-9,14-15H,11-13H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin S by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50376510
(CHEMBL261673)Show InChI InChI=1S/C18H19N5O/c1-18(2,3)13-22-17-14(11-21-16(10-19)23-17)6-5-9-24-15-7-4-8-20-12-15/h4,7-8,11-12H,9,13H2,1-3H3,(H,21,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin L by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50376499
(CHEMBL263409)Show SMILES CC(C)(C)CN(Cc1ccc(cc1)C#CCn1cncn1)c1ccnc(n1)C#N Show InChI InChI=1S/C22H23N7/c1-22(2,3)15-28(21-10-11-25-20(13-23)27-21)14-19-8-6-18(7-9-19)5-4-12-29-17-24-16-26-29/h6-11,16-17H,12,14-15H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin L by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50376500
(CHEMBL261700)Show SMILES CC(C)(C)CN(Cc1ccc(cc1)C#CCN1CCC(CC1)N1CCCCC1)c1ccnc(n1)C#N Show InChI InChI=1S/C30H40N6/c1-30(2,3)24-36(29-13-16-32-28(22-31)33-29)23-26-11-9-25(10-12-26)8-7-17-34-20-14-27(15-21-34)35-18-5-4-6-19-35/h9-13,16,27H,4-6,14-15,17-21,23-24H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin L by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50376501
(CHEMBL408974)Show SMILES CC(C)(C)CN(Cc1ccc(cc1)C#CCN1CCCCC1)c1ccnc(n1)C#N Show InChI InChI=1S/C25H31N5/c1-25(2,3)20-30(24-13-14-27-23(18-26)28-24)19-22-11-9-21(10-12-22)8-7-17-29-15-5-4-6-16-29/h9-14H,4-6,15-17,19-20H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin L by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50376502
(CHEMBL410520)Show SMILES CC(=O)N1CCN(CC#Cc2ccc(CN(CC(C)(C)C)c3ccnc(n3)C#N)cc2)CC1 Show InChI InChI=1S/C26H32N6O/c1-21(33)31-16-14-30(15-17-31)13-5-6-22-7-9-23(10-8-22)19-32(20-26(2,3)4)25-11-12-28-24(18-27)29-25/h7-12H,13-17,19-20H2,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin L by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50376503
(CHEMBL261516)Show SMILES CN1CCN(CC#Cc2ccc(CN(CC(C)(C)C)c3ccnc(n3)C#N)cc2)CC1 Show InChI InChI=1S/C25H32N6/c1-25(2,3)20-31(24-11-12-27-23(18-26)28-24)19-22-9-7-21(8-10-22)6-5-13-30-16-14-29(4)15-17-30/h7-12H,13-17,19-20H2,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin L by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50376504
(CHEMBL258640)Show SMILES CC(C)(C)CN(Cc1ccc(Cn2cncn2)cc1)c1ccnc(n1)C#N Show InChI InChI=1S/C20H23N7/c1-20(2,3)13-26(19-8-9-23-18(10-21)25-19)11-16-4-6-17(7-5-16)12-27-15-22-14-24-27/h4-9,14-15H,11-13H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin L by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50376505
(CHEMBL541991)Show InChI InChI=1S/C17H19IN4/c1-17(2,3)12-22(11-13-4-6-14(18)7-5-13)16-8-9-20-15(10-19)21-16/h4-9H,11-12H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin L by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50376506
(CHEMBL261125)Show InChI InChI=1S/C17H20N4/c1-17(2,3)13-21(12-14-7-5-4-6-8-14)16-9-10-19-15(11-18)20-16/h4-10H,12-13H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin L by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50376507
(CHEMBL429147)Show SMILES CC(C)(C)CNc1nc(ncc1C#CCN1CCN(CC1)S(=O)(=O)CCCCl)C#N Show InChI InChI=1S/C20H29ClN6O2S/c1-20(2,3)16-24-19-17(15-23-18(14-22)25-19)6-4-8-26-9-11-27(12-10-26)30(28,29)13-5-7-21/h15H,5,7-13,16H2,1-3H3,(H,23,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin L by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50376508
(CHEMBL261455)Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC#Cc2cnc(nc2NCC(C)(C)C)C#N)CC1 Show InChI InChI=1S/C24H30N6O3S/c1-24(2,3)18-27-23-19(17-26-22(16-25)28-23)6-5-11-29-12-14-30(15-13-29)34(31,32)21-9-7-20(33-4)8-10-21/h7-10,17H,11-15,18H2,1-4H3,(H,26,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin L by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin S
(Homo sapiens (Human)) | BDBM50376508
(CHEMBL261455)Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC#Cc2cnc(nc2NCC(C)(C)C)C#N)CC1 Show InChI InChI=1S/C24H30N6O3S/c1-24(2,3)18-27-23-19(17-26-22(16-25)28-23)6-5-11-29-12-14-30(15-13-29)34(31,32)21-9-7-20(33-4)8-10-21/h7-10,17H,11-15,18H2,1-4H3,(H,26,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin S by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin S
(Homo sapiens (Human)) | BDBM50376499
(CHEMBL263409)Show SMILES CC(C)(C)CN(Cc1ccc(cc1)C#CCn1cncn1)c1ccnc(n1)C#N Show InChI InChI=1S/C22H23N7/c1-22(2,3)15-28(21-10-11-25-20(13-23)27-21)14-19-8-6-18(7-9-19)5-4-12-29-17-24-16-26-29/h6-11,16-17H,12,14-15H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin S by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin S
(Homo sapiens (Human)) | BDBM50376500
(CHEMBL261700)Show SMILES CC(C)(C)CN(Cc1ccc(cc1)C#CCN1CCC(CC1)N1CCCCC1)c1ccnc(n1)C#N Show InChI InChI=1S/C30H40N6/c1-30(2,3)24-36(29-13-16-32-28(22-31)33-29)23-26-11-9-25(10-12-26)8-7-17-34-20-14-27(15-21-34)35-18-5-4-6-19-35/h9-13,16,27H,4-6,14-15,17-21,23-24H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin S by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin S
(Homo sapiens (Human)) | BDBM50376501
(CHEMBL408974)Show SMILES CC(C)(C)CN(Cc1ccc(cc1)C#CCN1CCCCC1)c1ccnc(n1)C#N Show InChI InChI=1S/C25H31N5/c1-25(2,3)20-30(24-13-14-27-23(18-26)28-24)19-22-11-9-21(10-12-22)8-7-17-29-15-5-4-6-16-29/h9-14H,4-6,15-17,19-20H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin S by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin S
(Homo sapiens (Human)) | BDBM50376502
(CHEMBL410520)Show SMILES CC(=O)N1CCN(CC#Cc2ccc(CN(CC(C)(C)C)c3ccnc(n3)C#N)cc2)CC1 Show InChI InChI=1S/C26H32N6O/c1-21(33)31-16-14-30(15-17-31)13-5-6-22-7-9-23(10-8-22)19-32(20-26(2,3)4)25-11-12-28-24(18-27)29-25/h7-12H,13-17,19-20H2,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin S by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin S
(Homo sapiens (Human)) | BDBM50376503
(CHEMBL261516)Show SMILES CN1CCN(CC#Cc2ccc(CN(CC(C)(C)C)c3ccnc(n3)C#N)cc2)CC1 Show InChI InChI=1S/C25H32N6/c1-25(2,3)20-31(24-11-12-27-23(18-26)28-24)19-22-9-7-21(8-10-22)6-5-13-30-16-14-29(4)15-17-30/h7-12H,13-17,19-20H2,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin S by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin S
(Homo sapiens (Human)) | BDBM50376505
(CHEMBL541991)Show InChI InChI=1S/C17H19IN4/c1-17(2,3)12-22(11-13-4-6-14(18)7-5-13)16-8-9-20-15(10-19)21-16/h4-9H,11-12H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin S by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Cathepsin S
(Homo sapiens (Human)) | BDBM50376506
(CHEMBL261125)Show InChI InChI=1S/C17H20N4/c1-17(2,3)13-21(12-14-7-5-4-6-8-14)16-9-10-19-15(11-18)20-16/h4-10H,12-13H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin S by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50376512
(CHEMBL261513)Show InChI InChI=1S/C21H23N5/c1-21(2,3)15-24-20-16(12-23-19(11-22)25-20)9-6-10-26-13-17-7-4-5-8-18(17)14-26/h4-5,7-8,12H,10,13-15H2,1-3H3,(H,23,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cathepsin L by fluorescence assay |
Bioorg Med Chem Lett 18: 2599-603 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.036
BindingDB Entry DOI: 10.7270/Q2HT2Q6P |
More data for this
Ligand-Target Pair | |
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