Found 56 hits Enz. Inhib. hit(s) with all data for entry = 50039159 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318564
((1R,2S,3r,4R,5S,6s)-6-((1-dodecyl-1H-1,2,3-triazol...)Show SMILES CCCCCCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C21H40N4O5/c1-2-3-4-5-6-7-8-9-10-11-12-25-14-15(23-24-25)13-22-16-17(26)19(28)21(30)20(29)18(16)27/h14,16-22,26-30H,2-13H2,1H3/t16-,17-,18+,19+,20-,21- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 60 | n/a | n/a | n/a | n/a | n/a | n/a | 5.2 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysis |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318563
((1R,2S,3r,4R,5S,6s)-6-[(1-Tetradecyl-1H-1,2,3-tria...)Show SMILES CCCCCCCCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C23H44N4O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-27-16-17(25-26-27)15-24-18-19(28)21(30)23(32)22(31)20(18)29/h16,18-24,28-32H,2-15H2,1H3/t18-,19-,20+,21+,22-,23- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 80 | n/a | n/a | n/a | n/a | n/a | n/a | 5.2 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysis |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318562
((1R,2S,3r,4R,5S,6s)-6-[(1-Decyl-1H-1,2,3-triazol-4...)Show SMILES CCCCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C19H36N4O5/c1-2-3-4-5-6-7-8-9-10-23-12-13(21-22-23)11-20-14-15(24)17(26)19(28)18(27)16(14)25/h12,14-20,24-28H,2-11H2,1H3/t14-,15-,16+,17+,18-,19- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 90 | n/a | n/a | n/a | n/a | n/a | n/a | 5.2 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysis |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM18358
((2R,3R,4R,5S)-2-(hydroxymethyl)-1-nonylpiperidine-...)Show SMILES CCCCCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO Show InChI InChI=1S/C15H31NO4/c1-2-3-4-5-6-7-8-9-16-10-13(18)15(20)14(19)12(16)11-17/h12-15,17-20H,2-11H2,1H3/t12-,13+,14-,15-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| MMDB PDB Article PubMed
| 300 | n/a | n/a | n/a | n/a | n/a | n/a | 5.2 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysis |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318560
(CHEMBL1083795 | N-decylaminocyclitol)Show SMILES CCCCCCCCCCN[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C16H33NO5/c1-2-3-4-5-6-7-8-9-10-17-11-12(18)14(20)16(22)15(21)13(11)19/h11-22H,2-10H2,1H3/t11-,12-,13+,14+,15-,16- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 300 | n/a | n/a | n/a | n/a | n/a | n/a | 5.2 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysis |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318561
((1R,2S,3r,4R,5S,6s)-6-[(1-Nonyl-1H-1,2,3-triazol-4...)Show SMILES CCCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C18H34N4O5/c1-2-3-4-5-6-7-8-9-22-11-12(20-21-22)10-19-13-14(23)16(25)18(27)17(26)15(13)24/h11,13-19,23-27H,2-10H2,1H3/t13-,14-,15+,16+,17-,18- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 330 | n/a | n/a | n/a | n/a | n/a | n/a | 5.2 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysis |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318559
((1R,2S,3r,4R,5S,6s)-6-[(1-Octyl-1H-1,2,3-triazol-4...)Show SMILES CCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C17H32N4O5/c1-2-3-4-5-6-7-8-21-10-11(19-20-21)9-18-12-13(22)15(24)17(26)16(25)14(12)23/h10,12-18,22-26H,2-9H2,1H3/t12-,13-,14+,15+,16-,17- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 5.2 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysis |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318558
((1R,2S,3r,4R,5S,6s)-6-((1-(6-propoxyhexyl)-1H-1,2,...)Show SMILES CCCOCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C18H34N4O6/c1-2-8-28-9-6-4-3-5-7-22-11-12(20-21-22)10-19-13-14(23)16(25)18(27)17(26)15(13)24/h11,13-19,23-27H,2-10H2,1H3/t13-,14-,15+,16+,17-,18- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 5.2 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysis |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318557
((1R,2S,3r,4R,5S,6s)-6-(3-(1-decyl-1H-1,2,3-triazol...)Show SMILES CCCCCCCCCCn1cc(CCCN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C21H40N4O5/c1-2-3-4-5-6-7-8-9-13-25-14-15(23-24-25)11-10-12-22-16-17(26)19(28)21(30)20(29)18(16)27/h14,16-22,26-30H,2-13H2,1H3/t16-,17-,18+,19+,20-,21- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 7.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 5.2 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysis |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318556
((1R,2S,3r,4R,5S,6s)-6-[(1-Phenethyl-1H-1,2,3-triaz...)Show SMILES O[C@H]1[C@H](O)[C@@H](O)[C@H](NCc2cn(CCc3ccccc3)nn2)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C17H24N4O5/c22-13-12(14(23)16(25)17(26)15(13)24)18-8-11-9-21(20-19-11)7-6-10-4-2-1-3-5-10/h1-5,9,12-18,22-26H,6-8H2/t12-,13-,14+,15+,16-,17- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.91E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 5.2 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysis |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318554
((1R,2S,3r,4R,5S,6s)-6-(3-(1-octyl-1H-1,2,3-triazol...)Show SMILES CCCCCCCCn1cc(CCCN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C19H36N4O5/c1-2-3-4-5-6-7-11-23-12-13(21-22-23)9-8-10-20-14-15(24)17(26)19(28)18(27)16(14)25/h12,14-20,24-28H,2-11H2,1H3/t14-,15-,16+,17+,18-,19- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.99E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 5.2 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysis |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318555
((1R,2S,3r,4R,5S,6s)-6-[2-(1-Undecyl-1H-1,2,3-triaz...)Show SMILES CCCCCCCCCCCn1cc(CCN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C21H40N4O5/c1-2-3-4-5-6-7-8-9-10-13-25-14-15(23-24-25)11-12-22-16-17(26)19(28)21(30)20(29)18(16)27/h14,16-22,26-30H,2-13H2,1H3/t16-,17-,18+,19+,20-,21- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 5.2 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysis |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318564
((1R,2S,3r,4R,5S,6s)-6-((1-dodecyl-1H-1,2,3-triazol...)Show SMILES CCCCCCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C21H40N4O5/c1-2-3-4-5-6-7-8-9-10-11-12-25-14-15(23-24-25)13-22-16-17(26)19(28)21(30)20(29)18(16)27/h14,16-22,26-30H,2-13H2,1H3/t16-,17-,18+,19+,20-,21- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | 5.2 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 5.2 after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318564
((1R,2S,3r,4R,5S,6s)-6-((1-dodecyl-1H-1,2,3-triazol...)Show SMILES CCCCCCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C21H40N4O5/c1-2-3-4-5-6-7-8-9-10-11-12-25-14-15(23-24-25)13-22-16-17(26)19(28)21(30)20(29)18(16)27/h14,16-22,26-30H,2-13H2,1H3/t16-,17-,18+,19+,20-,21- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 30.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318564
((1R,2S,3r,4R,5S,6s)-6-((1-dodecyl-1H-1,2,3-triazol...)Show SMILES CCCCCCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C21H40N4O5/c1-2-3-4-5-6-7-8-9-10-11-12-25-14-15(23-24-25)13-22-16-17(26)19(28)21(30)20(29)18(16)27/h14,16-22,26-30H,2-13H2,1H3/t16-,17-,18+,19+,20-,21- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 7.4 after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318563
((1R,2S,3r,4R,5S,6s)-6-[(1-Tetradecyl-1H-1,2,3-tria...)Show SMILES CCCCCCCCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C23H44N4O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-27-16-17(25-26-27)15-24-18-19(28)21(30)23(32)22(31)20(18)29/h16,18-24,28-32H,2-15H2,1H3/t18-,19-,20+,21+,22-,23- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 89.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318562
((1R,2S,3r,4R,5S,6s)-6-[(1-Decyl-1H-1,2,3-triazol-4...)Show SMILES CCCCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C19H36N4O5/c1-2-3-4-5-6-7-8-9-10-23-12-13(21-22-23)11-20-14-15(24)17(26)19(28)18(27)16(14)25/h12,14-20,24-28H,2-11H2,1H3/t14-,15-,16+,17+,18-,19- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 7.4 after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318563
((1R,2S,3r,4R,5S,6s)-6-[(1-Tetradecyl-1H-1,2,3-tria...)Show SMILES CCCCCCCCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C23H44N4O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-27-16-17(25-26-27)15-24-18-19(28)21(30)23(32)22(31)20(18)29/h16,18-24,28-32H,2-15H2,1H3/t18-,19-,20+,21+,22-,23- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | 5.2 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 5.2 after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318562
((1R,2S,3r,4R,5S,6s)-6-[(1-Decyl-1H-1,2,3-triazol-4...)Show SMILES CCCCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C19H36N4O5/c1-2-3-4-5-6-7-8-9-10-23-12-13(21-22-23)11-20-14-15(24)17(26)19(28)18(27)16(14)25/h12,14-20,24-28H,2-11H2,1H3/t14-,15-,16+,17+,18-,19- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 93.3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318562
((1R,2S,3r,4R,5S,6s)-6-[(1-Decyl-1H-1,2,3-triazol-4...)Show SMILES CCCCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C19H36N4O5/c1-2-3-4-5-6-7-8-9-10-23-12-13(21-22-23)11-20-14-15(24)17(26)19(28)18(27)16(14)25/h12,14-20,24-28H,2-11H2,1H3/t14-,15-,16+,17+,18-,19- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | 5.2 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 5.2 after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318563
((1R,2S,3r,4R,5S,6s)-6-[(1-Tetradecyl-1H-1,2,3-tria...)Show SMILES CCCCCCCCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C23H44N4O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-27-16-17(25-26-27)15-24-18-19(28)21(30)23(32)22(31)20(18)29/h16,18-24,28-32H,2-15H2,1H3/t18-,19-,20+,21+,22-,23- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 7.4 after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318561
((1R,2S,3r,4R,5S,6s)-6-[(1-Nonyl-1H-1,2,3-triazol-4...)Show SMILES CCCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C18H34N4O5/c1-2-3-4-5-6-7-8-9-22-11-12(20-21-22)10-19-13-14(23)16(25)18(27)17(26)15(13)24/h11,13-19,23-27H,2-10H2,1H3/t13-,14-,15+,16+,17-,18- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 7.4 after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318561
((1R,2S,3r,4R,5S,6s)-6-[(1-Nonyl-1H-1,2,3-triazol-4...)Show SMILES CCCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C18H34N4O5/c1-2-3-4-5-6-7-8-9-22-11-12(20-21-22)10-19-13-14(23)16(25)18(27)17(26)15(13)24/h11,13-19,23-27H,2-10H2,1H3/t13-,14-,15+,16+,17-,18- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | 5.2 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 5.2 after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318561
((1R,2S,3r,4R,5S,6s)-6-[(1-Nonyl-1H-1,2,3-triazol-4...)Show SMILES CCCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C18H34N4O5/c1-2-3-4-5-6-7-8-9-22-11-12(20-21-22)10-19-13-14(23)16(25)18(27)17(26)15(13)24/h11,13-19,23-27H,2-10H2,1H3/t13-,14-,15+,16+,17-,18- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 224 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM18358
((2R,3R,4R,5S)-2-(hydroxymethyl)-1-nonylpiperidine-...)Show SMILES CCCCCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO Show InChI InChI=1S/C15H31NO4/c1-2-3-4-5-6-7-8-9-16-10-13(18)15(20)14(19)12(16)11-17/h12-15,17-20H,2-11H2,1H3/t12-,13+,14-,15-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| MMDB PDB Article PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 7.4 after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM18358
((2R,3R,4R,5S)-2-(hydroxymethyl)-1-nonylpiperidine-...)Show SMILES CCCCCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO Show InChI InChI=1S/C15H31NO4/c1-2-3-4-5-6-7-8-9-16-10-13(18)15(20)14(19)12(16)11-17/h12-15,17-20H,2-11H2,1H3/t12-,13+,14-,15-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| MMDB PDB Article PubMed
| n/a | n/a | 660 | n/a | n/a | n/a | n/a | 5.2 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 5.2 after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318559
((1R,2S,3r,4R,5S,6s)-6-[(1-Octyl-1H-1,2,3-triazol-4...)Show SMILES CCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C17H32N4O5/c1-2-3-4-5-6-7-8-21-10-11(19-20-21)9-18-12-13(22)15(24)17(26)16(25)14(12)23/h10,12-18,22-26H,2-9H2,1H3/t12-,13-,14+,15+,16-,17- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | 5.2 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 5.2 after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318559
((1R,2S,3r,4R,5S,6s)-6-[(1-Octyl-1H-1,2,3-triazol-4...)Show SMILES CCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C17H32N4O5/c1-2-3-4-5-6-7-8-21-10-11(19-20-21)9-18-12-13(22)15(24)17(26)16(25)14(12)23/h10,12-18,22-26H,2-9H2,1H3/t12-,13-,14+,15+,16-,17- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318559
((1R,2S,3r,4R,5S,6s)-6-[(1-Octyl-1H-1,2,3-triazol-4...)Show SMILES CCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C17H32N4O5/c1-2-3-4-5-6-7-8-21-10-11(19-20-21)9-18-12-13(22)15(24)17(26)16(25)14(12)23/h10,12-18,22-26H,2-9H2,1H3/t12-,13-,14+,15+,16-,17- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 7.4 after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318557
((1R,2S,3r,4R,5S,6s)-6-(3-(1-decyl-1H-1,2,3-triazol...)Show SMILES CCCCCCCCCCn1cc(CCCN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C21H40N4O5/c1-2-3-4-5-6-7-8-9-13-25-14-15(23-24-25)11-10-12-22-16-17(26)19(28)21(30)20(29)18(16)27/h14,16-22,26-30H,2-13H2,1H3/t16-,17-,18+,19+,20-,21- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 7.4 after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318560
(CHEMBL1083795 | N-decylaminocyclitol)Show SMILES CCCCCCCCCCN[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C16H33NO5/c1-2-3-4-5-6-7-8-9-10-17-11-12(18)14(20)16(22)15(21)13(11)19/h11-22H,2-10H2,1H3/t11-,12-,13+,14+,15-,16- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | 5.2 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 5.2 after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318557
((1R,2S,3r,4R,5S,6s)-6-(3-(1-decyl-1H-1,2,3-triazol...)Show SMILES CCCCCCCCCCn1cc(CCCN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C21H40N4O5/c1-2-3-4-5-6-7-8-9-13-25-14-15(23-24-25)11-10-12-22-16-17(26)19(28)21(30)20(29)18(16)27/h14,16-22,26-30H,2-13H2,1H3/t16-,17-,18+,19+,20-,21- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318557
((1R,2S,3r,4R,5S,6s)-6-(3-(1-decyl-1H-1,2,3-triazol...)Show SMILES CCCCCCCCCCn1cc(CCCN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C21H40N4O5/c1-2-3-4-5-6-7-8-9-13-25-14-15(23-24-25)11-10-12-22-16-17(26)19(28)21(30)20(29)18(16)27/h14,16-22,26-30H,2-13H2,1H3/t16-,17-,18+,19+,20-,21- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | 5.2 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 5.2 after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318555
((1R,2S,3r,4R,5S,6s)-6-[2-(1-Undecyl-1H-1,2,3-triaz...)Show SMILES CCCCCCCCCCCn1cc(CCN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C21H40N4O5/c1-2-3-4-5-6-7-8-9-10-13-25-14-15(23-24-25)11-12-22-16-17(26)19(28)21(30)20(29)18(16)27/h14,16-22,26-30H,2-13H2,1H3/t16-,17-,18+,19+,20-,21- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 7.4 after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318558
((1R,2S,3r,4R,5S,6s)-6-((1-(6-propoxyhexyl)-1H-1,2,...)Show SMILES CCCOCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C18H34N4O6/c1-2-8-28-9-6-4-3-5-7-22-11-12(20-21-22)10-19-13-14(23)16(25)18(27)17(26)15(13)24/h11,13-19,23-27H,2-10H2,1H3/t13-,14-,15+,16+,17-,18- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.20E+3 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 7.4 after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318558
((1R,2S,3r,4R,5S,6s)-6-((1-(6-propoxyhexyl)-1H-1,2,...)Show SMILES CCCOCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C18H34N4O6/c1-2-8-28-9-6-4-3-5-7-22-11-12(20-21-22)10-19-13-14(23)16(25)18(27)17(26)15(13)24/h11,13-19,23-27H,2-10H2,1H3/t13-,14-,15+,16+,17-,18- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.40E+3 | n/a | n/a | n/a | n/a | 5.2 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 5.2 after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318556
((1R,2S,3r,4R,5S,6s)-6-[(1-Phenethyl-1H-1,2,3-triaz...)Show SMILES O[C@H]1[C@H](O)[C@@H](O)[C@H](NCc2cn(CCc3ccccc3)nn2)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C17H24N4O5/c22-13-12(14(23)16(25)17(26)15(13)24)18-8-11-9-21(20-19-11)7-6-10-4-2-1-3-5-10/h1-5,9,12-18,22-26H,6-8H2/t12-,13-,14+,15+,16-,17- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318556
((1R,2S,3r,4R,5S,6s)-6-[(1-Phenethyl-1H-1,2,3-triaz...)Show SMILES O[C@H]1[C@H](O)[C@@H](O)[C@H](NCc2cn(CCc3ccccc3)nn2)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C17H24N4O5/c22-13-12(14(23)16(25)17(26)15(13)24)18-8-11-9-21(20-19-11)7-6-10-4-2-1-3-5-10/h1-5,9,12-18,22-26H,6-8H2/t12-,13-,14+,15+,16-,17- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.08E+4 | n/a | n/a | n/a | n/a | 5.2 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 5.2 after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318553
((1R,2S,3r,4R,5S,6s)-6-[2-(1-Nonyl-1H-1,2,3-triazol...)Show SMILES CCCCCCCCCn1cc(CCN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C19H36N4O5/c1-2-3-4-5-6-7-8-11-23-12-13(21-22-23)9-10-20-14-15(24)17(26)19(28)18(27)16(14)25/h12,14-20,24-28H,2-11H2,1H3/t14-,15-,16+,17+,18-,19- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 7.4 after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318558
((1R,2S,3r,4R,5S,6s)-6-((1-(6-propoxyhexyl)-1H-1,2,...)Show SMILES CCCOCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C18H34N4O6/c1-2-8-28-9-6-4-3-5-7-22-11-12(20-21-22)10-19-13-14(23)16(25)18(27)17(26)15(13)24/h11,13-19,23-27H,2-10H2,1H3/t13-,14-,15+,16+,17-,18- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.38E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318554
((1R,2S,3r,4R,5S,6s)-6-(3-(1-octyl-1H-1,2,3-triazol...)Show SMILES CCCCCCCCn1cc(CCCN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C19H36N4O5/c1-2-3-4-5-6-7-11-23-12-13(21-22-23)9-8-10-20-14-15(24)17(26)19(28)18(27)16(14)25/h12,14-20,24-28H,2-11H2,1H3/t14-,15-,16+,17+,18-,19- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.82E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 7.4 after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318556
((1R,2S,3r,4R,5S,6s)-6-[(1-Phenethyl-1H-1,2,3-triaz...)Show SMILES O[C@H]1[C@H](O)[C@@H](O)[C@H](NCc2cn(CCc3ccccc3)nn2)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C17H24N4O5/c22-13-12(14(23)16(25)17(26)15(13)24)18-8-11-9-21(20-19-11)7-6-10-4-2-1-3-5-10/h1-5,9,12-18,22-26H,6-8H2/t12-,13-,14+,15+,16-,17- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 7.4 after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318555
((1R,2S,3r,4R,5S,6s)-6-[2-(1-Undecyl-1H-1,2,3-triaz...)Show SMILES CCCCCCCCCCCn1cc(CCN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C21H40N4O5/c1-2-3-4-5-6-7-8-9-10-13-25-14-15(23-24-25)11-12-22-16-17(26)19(28)21(30)20(29)18(16)27/h14,16-22,26-30H,2-13H2,1H3/t16-,17-,18+,19+,20-,21- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.54E+4 | n/a | n/a | n/a | n/a | 5.2 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 5.2 after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318555
((1R,2S,3r,4R,5S,6s)-6-[2-(1-Undecyl-1H-1,2,3-triaz...)Show SMILES CCCCCCCCCCCn1cc(CCN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C21H40N4O5/c1-2-3-4-5-6-7-8-9-10-13-25-14-15(23-24-25)11-12-22-16-17(26)19(28)21(30)20(29)18(16)27/h14,16-22,26-30H,2-13H2,1H3/t16-,17-,18+,19+,20-,21- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.57E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318554
((1R,2S,3r,4R,5S,6s)-6-(3-(1-octyl-1H-1,2,3-triazol...)Show SMILES CCCCCCCCn1cc(CCCN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C19H36N4O5/c1-2-3-4-5-6-7-11-23-12-13(21-22-23)9-8-10-20-14-15(24)17(26)19(28)18(27)16(14)25/h12,14-20,24-28H,2-11H2,1H3/t14-,15-,16+,17+,18-,19- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.54E+4 | n/a | n/a | n/a | n/a | 5.2 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 5.2 after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318554
((1R,2S,3r,4R,5S,6s)-6-(3-(1-octyl-1H-1,2,3-triazol...)Show SMILES CCCCCCCCn1cc(CCCN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C19H36N4O5/c1-2-3-4-5-6-7-11-23-12-13(21-22-23)9-8-10-20-14-15(24)17(26)19(28)18(27)16(14)25/h12,14-20,24-28H,2-11H2,1H3/t14-,15-,16+,17+,18-,19- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.55E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318550
((1R,2S,3r,4R,5S,6s)-6-(3-(1-hexyl-1H-1,2,3-triazol...)Show SMILES CCCCCCn1cc(CCCN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C17H32N4O5/c1-2-3-4-5-9-21-10-11(19-20-21)7-6-8-18-12-13(22)15(24)17(26)16(25)14(12)23/h10,12-18,22-26H,2-9H2,1H3/t12-,13-,14+,15+,16-,17- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.46E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 7.4 after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318553
((1R,2S,3r,4R,5S,6s)-6-[2-(1-Nonyl-1H-1,2,3-triazol...)Show SMILES CCCCCCCCCn1cc(CCN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C19H36N4O5/c1-2-3-4-5-6-7-8-11-23-12-13(21-22-23)9-10-20-14-15(24)17(26)19(28)18(27)16(14)25/h12,14-20,24-28H,2-11H2,1H3/t14-,15-,16+,17+,18-,19- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.47E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318553
((1R,2S,3r,4R,5S,6s)-6-[2-(1-Nonyl-1H-1,2,3-triazol...)Show SMILES CCCCCCCCCn1cc(CCN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C19H36N4O5/c1-2-3-4-5-6-7-8-11-23-12-13(21-22-23)9-10-20-14-15(24)17(26)19(28)18(27)16(14)25/h12,14-20,24-28H,2-11H2,1H3/t14-,15-,16+,17+,18-,19- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.47E+4 | n/a | n/a | n/a | n/a | 5.2 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 5.2 after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50318552
((1R,2S,3r,4R,5S,6s)-6-[2-(1-Octyl-1H-1,2,3-triazol...)Show SMILES CCCCCCCCn1cc(CCN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C18H34N4O5/c1-2-3-4-5-6-7-10-22-11-12(20-21-22)8-9-19-13-14(23)16(25)18(27)17(26)15(13)24/h11,13-19,23-27H,2-10H2,1H3/t13-,14-,15+,16+,17-,18- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.59E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Universitat de Barcelona
Curated by ChEMBL
| Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 7.4 after 10 mins by fluorimetry |
J Med Chem 53: 5248-55 (2010)
Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1 |
More data for this Ligand-Target Pair | |