Compile Data Set for Download or QSAR

Found 24 hits Enz. Inhib. hit(s) with all data for entry = 50049006   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50232782 (CHEMBL4083975) Show SMILES COc1ccc2C(=O)\C(Oc2c1CN1CCNCC1)=C\c1c[nH]c2nc(F)ccc12 Show InChI InChI=1S/C22H21FN4O3/c1-29-17-4-2-15-20(28)18(10-13-11-25-22-14(13)3-5-19(23)26-22)30-21(15)16(17)12-27-8-6-24-7-9-27/h2-5,10-11,24H,6-9,12H2,1H3,(H,25,26)/b18-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.280	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin) using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assay				ACS Med Chem Lett 8: 504-509 (2017) Article DOI: 10.1021/acsmedchemlett.6b00518 BindingDB Entry DOI: 10.7270/Q2N58PK5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50232778 (CHEMBL4062256) Show SMILES COc1ccc2C(=O)\C(Oc2c1CN1CCNCC1)=C\c1c[nH]c2nc(Cl)ccc12 Show InChI InChI=1S/C22H21ClN4O3/c1-29-17-4-2-15-20(28)18(10-13-11-25-22-14(13)3-5-19(23)26-22)30-21(15)16(17)12-27-8-6-24-7-9-27/h2-5,10-11,24H,6-9,12H2,1H3,(H,25,26)/b18-10-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of full length recombinant human N-terminal GST-tagged PIM3 (1 to 326 end residues) expressed in baculovirus infected sf21 cells using S6K...				ACS Med Chem Lett 8: 504-509 (2017) Article DOI: 10.1021/acsmedchemlett.6b00518 BindingDB Entry DOI: 10.7270/Q2N58PK5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50232778 (CHEMBL4062256) Show SMILES COc1ccc2C(=O)\C(Oc2c1CN1CCNCC1)=C\c1c[nH]c2nc(Cl)ccc12 Show InChI InChI=1S/C22H21ClN4O3/c1-29-17-4-2-15-20(28)18(10-13-11-25-22-14(13)3-5-19(23)26-22)30-21(15)16(17)12-27-8-6-24-7-9-27/h2-5,10-11,24H,6-9,12H2,1H3,(H,25,26)/b18-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.410	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin) using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assay				ACS Med Chem Lett 8: 504-509 (2017) Article DOI: 10.1021/acsmedchemlett.6b00518 BindingDB Entry DOI: 10.7270/Q2N58PK5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50232778 (CHEMBL4062256) Show SMILES COc1ccc2C(=O)\C(Oc2c1CN1CCNCC1)=C\c1c[nH]c2nc(Cl)ccc12 Show InChI InChI=1S/C22H21ClN4O3/c1-29-17-4-2-15-20(28)18(10-13-11-25-22-14(13)3-5-19(23)26-22)30-21(15)16(17)12-27-8-6-24-7-9-27/h2-5,10-11,24H,6-9,12H2,1H3,(H,25,26)/b18-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.490	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of full length recombinant human N-terminal His-tagged PIM1 (1 to 313 end residues) expressed in baculovirus infected sf21 cells using S6K...				ACS Med Chem Lett 8: 504-509 (2017) Article DOI: 10.1021/acsmedchemlett.6b00518 BindingDB Entry DOI: 10.7270/Q2N58PK5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50232779 (CHEMBL4060711) Show SMILES COc1ccc2C(=O)\C(Oc2c1CN1CCNCC1)=C\c1c[nH]c2nc(C)ccc12 Show InChI InChI=1S/C23H24N4O3/c1-14-3-4-16-15(12-25-23(16)26-14)11-20-21(28)17-5-6-19(29-2)18(22(17)30-20)13-27-9-7-24-8-10-27/h3-6,11-12,24H,7-10,13H2,1-2H3,(H,25,26)/b20-11-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.640	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin) using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assay				ACS Med Chem Lett 8: 504-509 (2017) Article DOI: 10.1021/acsmedchemlett.6b00518 BindingDB Entry DOI: 10.7270/Q2N58PK5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50391948 (CHEMBL2147767) Show SMILES COc1ccc2C(=O)C(Oc2c1CN1CCNCC1)=Cc1c[nH]c2ncccc12 |w:19.22| Show InChI InChI=1S/C22H22N4O3/c1-28-18-5-4-16-20(27)19(11-14-12-25-22-15(14)3-2-6-24-22)29-21(16)17(18)13-26-9-7-23-8-10-26/h2-6,11-12,23H,7-10,13H2,1H3,(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.840	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin) using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assay				ACS Med Chem Lett 8: 504-509 (2017) Article DOI: 10.1021/acsmedchemlett.6b00518 BindingDB Entry DOI: 10.7270/Q2N58PK5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50232780 (CHEMBL4061176) Show SMILES Oc1ccc2C(=O)\C(Oc2c1CN1CCNCC1)=C\c1c[nH]c2nc(Cl)ccc12 Show InChI InChI=1S/C21H19ClN4O3/c22-18-4-2-13-12(10-24-21(13)25-18)9-17-19(28)14-1-3-16(27)15(20(14)29-17)11-26-7-5-23-6-8-26/h1-4,9-10,23,27H,5-8,11H2,(H,24,25)/b17-9-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.880	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of full length recombinant human N-terminal GST-tagged PIM3 (1 to 326 end residues) expressed in baculovirus infected sf21 cells using S6K...				ACS Med Chem Lett 8: 504-509 (2017) Article DOI: 10.1021/acsmedchemlett.6b00518 BindingDB Entry DOI: 10.7270/Q2N58PK5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50232785 (CHEMBL4074201) Show SMILES CCc1ccc2c(\C=C3/Oc4c(ccc(OC)c4CN4CCNCC4)C3=O)c[nH]c2n1 Show InChI InChI=1S/C24H26N4O3/c1-3-16-4-5-17-15(13-26-24(17)27-16)12-21-22(29)18-6-7-20(30-2)19(23(18)31-21)14-28-10-8-25-9-11-28/h4-7,12-13,25H,3,8-11,14H2,1-2H3,(H,26,27)/b21-12-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin) using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assay				ACS Med Chem Lett 8: 504-509 (2017) Article DOI: 10.1021/acsmedchemlett.6b00518 BindingDB Entry DOI: 10.7270/Q2N58PK5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50232780 (CHEMBL4061176) Show SMILES Oc1ccc2C(=O)\C(Oc2c1CN1CCNCC1)=C\c1c[nH]c2nc(Cl)ccc12 Show InChI InChI=1S/C21H19ClN4O3/c22-18-4-2-13-12(10-24-21(13)25-18)9-17-19(28)14-1-3-16(27)15(20(14)29-17)11-26-7-5-23-6-8-26/h1-4,9-10,23,27H,5-8,11H2,(H,24,25)/b17-9-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of full length recombinant human N-terminal His-tagged PIM1 (1 to 313 end residues) expressed in baculovirus infected sf21 cells using S6K...				ACS Med Chem Lett 8: 504-509 (2017) Article DOI: 10.1021/acsmedchemlett.6b00518 BindingDB Entry DOI: 10.7270/Q2N58PK5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50232780 (CHEMBL4061176) Show SMILES Oc1ccc2C(=O)\C(Oc2c1CN1CCNCC1)=C\c1c[nH]c2nc(Cl)ccc12 Show InChI InChI=1S/C21H19ClN4O3/c22-18-4-2-13-12(10-24-21(13)25-18)9-17-19(28)14-1-3-16(27)15(20(14)29-17)11-26-7-5-23-6-8-26/h1-4,9-10,23,27H,5-8,11H2,(H,24,25)/b17-9-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin) using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assay				ACS Med Chem Lett 8: 504-509 (2017) Article DOI: 10.1021/acsmedchemlett.6b00518 BindingDB Entry DOI: 10.7270/Q2N58PK5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50232786 (CHEMBL4092704) Show SMILES Oc1ccc2C(=O)\C(Oc2c1CN1CCNCC1)=C\c1c[nH]c2nc(F)ccc12 Show InChI InChI=1S/C21H19FN4O3/c22-18-4-2-13-12(10-24-21(13)25-18)9-17-19(28)14-1-3-16(27)15(20(14)29-17)11-26-7-5-23-6-8-26/h1-4,9-10,23,27H,5-8,11H2,(H,24,25)/b17-9-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin) using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assay				ACS Med Chem Lett 8: 504-509 (2017) Article DOI: 10.1021/acsmedchemlett.6b00518 BindingDB Entry DOI: 10.7270/Q2N58PK5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50232777 (CHEMBL4102902) Show SMILES Oc1ccc2C(=O)\C(Oc2c1CN1CCNCC1)=C\c1c[nH]c2ncccc12 Show InChI InChI=1S/C21H20N4O3/c26-17-4-3-15-19(27)18(10-13-11-24-21-14(13)2-1-5-23-21)28-20(15)16(17)12-25-8-6-22-7-9-25/h1-5,10-11,22,26H,6-9,12H2,(H,23,24)/b18-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin) using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assay				ACS Med Chem Lett 8: 504-509 (2017) Article DOI: 10.1021/acsmedchemlett.6b00518 BindingDB Entry DOI: 10.7270/Q2N58PK5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50232787 (CHEMBL4073609) Show SMILES CCCCc1ccc2c(\C=C3/Oc4c(ccc(OC)c4CN4CCNCC4)C3=O)c[nH]c2n1 Show InChI InChI=1S/C26H30N4O3/c1-3-4-5-18-6-7-19-17(15-28-26(19)29-18)14-23-24(31)20-8-9-22(32-2)21(25(20)33-23)16-30-12-10-27-11-13-30/h6-9,14-15,27H,3-5,10-13,16H2,1-2H3,(H,28,29)/b23-14-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin) using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assay				ACS Med Chem Lett 8: 504-509 (2017) Article DOI: 10.1021/acsmedchemlett.6b00518 BindingDB Entry DOI: 10.7270/Q2N58PK5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50232776 (CHEMBL4084953) Show SMILES Cc1ccc2c(\C=C3/Oc4c(ccc(O)c4CN4CCNCC4)C3=O)c[nH]c2n1 Show InChI InChI=1S/C22H22N4O3/c1-13-2-3-15-14(11-24-22(15)25-13)10-19-20(28)16-4-5-18(27)17(21(16)29-19)12-26-8-6-23-7-9-26/h2-5,10-11,23,27H,6-9,12H2,1H3,(H,24,25)/b19-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin) using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assay				ACS Med Chem Lett 8: 504-509 (2017) Article DOI: 10.1021/acsmedchemlett.6b00518 BindingDB Entry DOI: 10.7270/Q2N58PK5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50232784 (CHEMBL4094705) Show SMILES CCCc1ccc2c(\C=C3/Oc4c(ccc(OC)c4CN4CCNCC4)C3=O)c[nH]c2n1 Show InChI InChI=1S/C25H28N4O3/c1-3-4-17-5-6-18-16(14-27-25(18)28-17)13-22-23(30)19-7-8-21(31-2)20(24(19)32-22)15-29-11-9-26-10-12-29/h5-8,13-14,26H,3-4,9-12,15H2,1-2H3,(H,27,28)/b22-13-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin) using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assay				ACS Med Chem Lett 8: 504-509 (2017) Article DOI: 10.1021/acsmedchemlett.6b00518 BindingDB Entry DOI: 10.7270/Q2N58PK5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50232783 (CHEMBL4100433) Show SMILES COc1ccc2C(=O)\C(Oc2c1CN1CCNCC1)=C\c1c[nH]c2nc(ccc12)-c1ccccc1 Show InChI InChI=1S/C28H26N4O3/c1-34-24-10-8-21-26(33)25(35-27(21)22(24)17-32-13-11-29-12-14-32)15-19-16-30-28-20(19)7-9-23(31-28)18-5-3-2-4-6-18/h2-10,15-16,29H,11-14,17H2,1H3,(H,30,31)/b25-15-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin) using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assay				ACS Med Chem Lett 8: 504-509 (2017) Article DOI: 10.1021/acsmedchemlett.6b00518 BindingDB Entry DOI: 10.7270/Q2N58PK5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50232781 (CHEMBL4065023) Show SMILES CCc1ccc2c(\C=C3/Oc4c(ccc(O)c4CN4CCNCC4)C3=O)c[nH]c2n1 Show InChI InChI=1S/C23H24N4O3/c1-2-15-3-4-16-14(12-25-23(16)26-15)11-20-21(29)17-5-6-19(28)18(22(17)30-20)13-27-9-7-24-8-10-27/h3-6,11-12,24,28H,2,7-10,13H2,1H3,(H,25,26)/b20-11-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin) using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assay				ACS Med Chem Lett 8: 504-509 (2017) Article DOI: 10.1021/acsmedchemlett.6b00518 BindingDB Entry DOI: 10.7270/Q2N58PK5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50232780 (CHEMBL4061176) Show SMILES Oc1ccc2C(=O)\C(Oc2c1CN1CCNCC1)=C\c1c[nH]c2nc(Cl)ccc12 Show InChI InChI=1S/C21H19ClN4O3/c22-18-4-2-13-12(10-24-21(13)25-18)9-17-19(28)14-1-3-16(27)15(20(14)29-17)11-26-7-5-23-6-8-26/h1-4,9-10,23,27H,5-8,11H2,(H,24,25)/b17-9-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of full length recombinant human N-terminal GST-tagged PIM2 (1 to 311 residues) expressed in baculovirus infected sf21 cells using S6K2 pe...				ACS Med Chem Lett 8: 504-509 (2017) Article DOI: 10.1021/acsmedchemlett.6b00518 BindingDB Entry DOI: 10.7270/Q2N58PK5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50232778 (CHEMBL4062256) Show SMILES COc1ccc2C(=O)\C(Oc2c1CN1CCNCC1)=C\c1c[nH]c2nc(Cl)ccc12 Show InChI InChI=1S/C22H21ClN4O3/c1-29-17-4-2-15-20(28)18(10-13-11-25-22-14(13)3-5-19(23)26-22)30-21(15)16(17)12-27-8-6-24-7-9-27/h2-5,10-11,24H,6-9,12H2,1H3,(H,25,26)/b18-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of full length recombinant human N-terminal GST-tagged PIM2 (1 to 311 residues) expressed in baculovirus infected sf21 cells using S6K2 pe...				ACS Med Chem Lett 8: 504-509 (2017) Article DOI: 10.1021/acsmedchemlett.6b00518 BindingDB Entry DOI: 10.7270/Q2N58PK5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50232785 (CHEMBL4074201) Show SMILES CCc1ccc2c(\C=C3/Oc4c(ccc(OC)c4CN4CCNCC4)C3=O)c[nH]c2n1 Show InChI InChI=1S/C24H26N4O3/c1-3-16-4-5-17-15(13-26-24(17)27-16)12-21-22(29)18-6-7-20(30-2)19(23(18)31-21)14-28-10-8-25-9-11-28/h4-7,12-13,25H,3,8-11,14H2,1-2H3,(H,26,27)/b21-12-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of full length recombinant human N-terminal GST-tagged PIM2 (1 to 311 residues) expressed in baculovirus infected sf21 cells using S6K2 pe...				ACS Med Chem Lett 8: 504-509 (2017) Article DOI: 10.1021/acsmedchemlett.6b00518 BindingDB Entry DOI: 10.7270/Q2N58PK5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50232779 (CHEMBL4060711) Show SMILES COc1ccc2C(=O)\C(Oc2c1CN1CCNCC1)=C\c1c[nH]c2nc(C)ccc12 Show InChI InChI=1S/C23H24N4O3/c1-14-3-4-16-15(12-25-23(16)26-14)11-20-21(28)17-5-6-19(29-2)18(22(17)30-20)13-27-9-7-24-8-10-27/h3-6,11-12,24H,7-10,13H2,1-2H3,(H,25,26)/b20-11-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of full length recombinant human N-terminal GST-tagged PIM2 (1 to 311 residues) expressed in baculovirus infected sf21 cells using S6K2 pe...				ACS Med Chem Lett 8: 504-509 (2017) Article DOI: 10.1021/acsmedchemlett.6b00518 BindingDB Entry DOI: 10.7270/Q2N58PK5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50391948 (CHEMBL2147767) Show SMILES COc1ccc2C(=O)C(Oc2c1CN1CCNCC1)=Cc1c[nH]c2ncccc12 |w:19.22| Show InChI InChI=1S/C22H22N4O3/c1-28-18-5-4-16-20(27)19(11-14-12-25-22-15(14)3-2-6-24-22)29-21(16)17(18)13-26-9-7-23-8-10-26/h2-6,11-12,23H,7-10,13H2,1H3,(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of full length recombinant human N-terminal GST-tagged PIM2 (1 to 311 residues) expressed in baculovirus infected sf21 cells using S6K2 pe...				ACS Med Chem Lett 8: 504-509 (2017) Article DOI: 10.1021/acsmedchemlett.6b00518 BindingDB Entry DOI: 10.7270/Q2N58PK5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50232777 (CHEMBL4102902) Show SMILES Oc1ccc2C(=O)\C(Oc2c1CN1CCNCC1)=C\c1c[nH]c2ncccc12 Show InChI InChI=1S/C21H20N4O3/c26-17-4-3-15-19(27)18(10-13-11-24-21-14(13)2-1-5-23-21)28-20(15)16(17)12-25-8-6-22-7-9-25/h1-5,10-11,22,26H,6-9,12H2,(H,23,24)/b18-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of full length recombinant human N-terminal GST-tagged PIM2 (1 to 311 residues) expressed in baculovirus infected sf21 cells using S6K2 pe...				ACS Med Chem Lett 8: 504-509 (2017) Article DOI: 10.1021/acsmedchemlett.6b00518 BindingDB Entry DOI: 10.7270/Q2N58PK5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50232776 (CHEMBL4084953) Show SMILES Cc1ccc2c(\C=C3/Oc4c(ccc(O)c4CN4CCNCC4)C3=O)c[nH]c2n1 Show InChI InChI=1S/C22H22N4O3/c1-13-2-3-15-14(11-24-22(15)25-13)10-19-20(28)16-4-5-18(27)17(21(16)29-19)12-26-8-6-23-7-9-26/h2-5,10-11,23,27H,6-9,12H2,1H3,(H,24,25)/b19-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of full length recombinant human N-terminal GST-tagged PIM2 (1 to 311 residues) expressed in baculovirus infected sf21 cells using S6K2 pe...				ACS Med Chem Lett 8: 504-509 (2017) Article DOI: 10.1021/acsmedchemlett.6b00518 BindingDB Entry DOI: 10.7270/Q2N58PK5
					More data for this Ligand-Target Pair