Compile Data Set for Download or QSAR

Found 65 hits Enz. Inhib. hit(s) with all data for entry = 50049195   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236166 (CHEMBL4069667) Show SMILES CCCCNc1nc(N)nc(C)c1CCCN1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C20H25N5O2/c1-3-4-11-22-17-14(13(2)23-20(21)24-17)10-7-12-25-18(26)15-8-5-6-9-16(15)19(25)27/h5-6,8-9H,3-4,7,10-12H2,1-2H3,(H3,21,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50236180 (CHEMBL4084584) Show SMILES CCCCNc1nc(N)nc(C)c1CCCC(C)(C)O Show InChI InChI=1S/C15H28N4O/c1-5-6-10-17-13-12(8-7-9-15(3,4)20)11(2)18-14(16)19-13/h20H,5-10H2,1-4H3,(H3,16,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.22E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR8 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236159 (CHEMBL4091116) Show SMILES CCCCNc1nc(N)nc(C)c1C Show InChI InChI=1S/C10H18N4/c1-4-5-6-12-9-7(2)8(3)13-10(11)14-9/h4-6H2,1-3H3,(H3,11,12,13,14)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50236186 (CHEMBL4061145) Show SMILES CCCCNc1nc(N)nc(C)c1C#CCN1CCOCC1 Show InChI InChI=1S/C16H25N5O/c1-3-4-7-18-15-14(13(2)19-16(17)20-15)6-5-8-21-9-11-22-12-10-21/h3-4,7-12H2,1-2H3,(H3,17,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.62E+4	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR8 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236189 (CHEMBL4077919) Show SMILES CCCCNc1nc(N)nc(C)c1CCCC1CCCCC1 Show InChI InChI=1S/C18H32N4/c1-3-4-13-20-17-16(14(2)21-18(19)22-17)12-8-11-15-9-6-5-7-10-15/h15H,3-13H2,1-2H3,(H3,19,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236170 (CHEMBL4074289) Show SMILES CCCCNc1nc(N)nc(C)c1CCCCO Show InChI InChI=1S/C13H24N4O/c1-3-4-8-15-12-11(7-5-6-9-18)10(2)16-13(14)17-12/h18H,3-9H2,1-2H3,(H3,14,15,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236158 (CHEMBL4074552) Show SMILES CCCCNc1nc(N)nc(C)c1CCCn1cccn1 Show InChI InChI=1S/C15H24N6/c1-3-4-8-17-14-13(12(2)19-15(16)20-14)7-5-10-21-11-6-9-18-21/h6,9,11H,3-5,7-8,10H2,1-2H3,(H3,16,17,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	398	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50236190 (CHEMBL4081065) Show SMILES CCCCNc1nc(N)nc(C)c1C#CCN1CCCCC1 Show InChI InChI=1S/C17H27N5/c1-3-4-10-19-16-15(14(2)20-17(18)21-16)9-8-13-22-11-6-5-7-12-22/h3-7,10-13H2,1-2H3,(H3,18,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.79E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR8 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236188 (CHEMBL4071479) Show SMILES CCCCNc1nc(N)nc(C)c1CCCN1CCN(C)CC1 Show InChI InChI=1S/C17H32N6/c1-4-5-8-19-16-15(14(2)20-17(18)21-16)7-6-9-23-12-10-22(3)11-13-23/h4-13H2,1-3H3,(H3,18,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	251	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236167 (CHEMBL4096879) Show SMILES CCCCNc1nc(N)nc(C)c1CCCN1Cc2ccccc2C1 Show InChI InChI=1S/C20H29N5/c1-3-4-11-22-19-18(15(2)23-20(21)24-19)10-7-12-25-13-16-8-5-6-9-17(16)14-25/h5-6,8-9H,3-4,7,10-14H2,1-2H3,(H3,21,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	375	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236144 (CHEMBL4089935) Show SMILES CCCCNc1nc(N)nc(C)c1CCc1ccccc1 Show InChI InChI=1S/C17H24N4/c1-3-4-12-19-16-15(13(2)20-17(18)21-16)11-10-14-8-6-5-7-9-14/h5-9H,3-4,10-12H2,1-2H3,(H3,18,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.82E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236180 (CHEMBL4084584) Show SMILES CCCCNc1nc(N)nc(C)c1CCCC(C)(C)O Show InChI InChI=1S/C15H28N4O/c1-5-6-10-17-13-12(8-7-9-15(3,4)20)11(2)18-14(16)19-13/h20H,5-10H2,1-4H3,(H3,16,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.89E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236169 (CHEMBL4105319) Show SMILES CCCCNc1nc(N)nc(C)c1CCCN1CCCC1 Show InChI InChI=1S/C16H29N5/c1-3-4-9-18-15-14(13(2)19-16(17)20-15)8-7-12-21-10-5-6-11-21/h3-12H2,1-2H3,(H3,17,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	562	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236156 (CHEMBL4090816) Show SMILES CCCCNc1nc(N)nc(C)c1CCCN1CCOCC1 Show InChI InChI=1S/C16H29N5O/c1-3-4-7-18-15-14(13(2)19-16(17)20-15)6-5-8-21-9-11-22-12-10-21/h3-12H2,1-2H3,(H3,17,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	46	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50236173 (CHEMBL4103484) Show SMILES CCCCNc1nc(N)nc(C)c1C#C[Si](C)(C)C Show InChI InChI=1S/C14H24N4Si/c1-6-7-9-16-13-12(8-10-19(3,4)5)11(2)17-14(15)18-13/h6-7,9H2,1-5H3,(H3,15,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.24E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR8 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236147 (CHEMBL4095966) Show SMILES CCCCNc1nc(N)nc(C)c1CCCCCc1ccccc1 Show InChI InChI=1S/C20H30N4/c1-3-4-15-22-19-18(16(2)23-20(21)24-19)14-10-6-9-13-17-11-7-5-8-12-17/h5,7-8,11-12H,3-4,6,9-10,13-15H2,1-2H3,(H3,21,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	265	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50236176 (CHEMBL4065677) Show SMILES CCCCNc1nc(N)nc(C)c1Cc1ccccc1 Show InChI InChI=1S/C16H22N4/c1-3-4-10-18-15-14(12(2)19-16(17)20-15)11-13-8-6-5-7-9-13/h5-9H,3-4,10-11H2,1-2H3,(H3,17,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR8 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50236172 (CHEMBL4085562) Show SMILES CCCCNc1nc(N)nc(C)c1C#CCCC Show InChI InChI=1S/C14H22N4/c1-4-6-8-9-12-11(3)17-14(15)18-13(12)16-10-7-5-2/h4-7,10H2,1-3H3,(H3,15,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR8 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50236171 (CHEMBL4093308) Show SMILES CCCCNc1nc(N)nc(C)c1C#C Show InChI InChI=1S/C11H16N4/c1-4-6-7-13-10-9(5-2)8(3)14-11(12)15-10/h2H,4,6-7H2,1,3H3,(H3,12,13,14,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR8 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50236175 (CHEMBL4088953) Show SMILES CCCCNc1nc(N)nc(C)c1CCCN1CCCCCC1 Show InChI InChI=1S/C18H33N5/c1-3-4-11-20-17-16(15(2)21-18(19)22-17)10-9-14-23-12-7-5-6-8-13-23/h3-14H2,1-2H3,(H3,19,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	178	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR8 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236177 (CHEMBL4069818) Show SMILES CCCCNc1nc(N)nc(C)c1CCCN(C)CCOC Show InChI InChI=1S/C16H31N5O/c1-5-6-9-18-15-14(13(2)19-16(17)20-15)8-7-10-21(3)11-12-22-4/h5-12H2,1-4H3,(H3,17,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.24E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236179 (CHEMBL4092273) Show SMILES CCCCNc1nc(N)nc(C)c1CCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C22H34N6/c1-3-4-12-24-21-20(18(2)25-22(23)26-21)11-8-13-27-14-16-28(17-15-27)19-9-6-5-7-10-19/h5-7,9-10H,3-4,8,11-17H2,1-2H3,(H3,23,24,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.16E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236191 (CHEMBL4083025) Show SMILES CCCCNc1nc(N)nc(C)c1CCCN1CCSCC1 Show InChI InChI=1S/C16H29N5S/c1-3-4-7-18-15-14(13(2)19-16(17)20-15)6-5-8-21-9-11-22-12-10-21/h3-12H2,1-2H3,(H3,17,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	714	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50236174 (CHEMBL4062920) Show SMILES CCCCNc1nc(N)nc(C)c1CCC(C)(C)O Show InChI InChI=1S/C14H26N4O/c1-5-6-9-16-12-11(7-8-14(3,4)19)10(2)17-13(15)18-12/h19H,5-9H2,1-4H3,(H3,15,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.14E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR8 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50236177 (CHEMBL4069818) Show SMILES CCCCNc1nc(N)nc(C)c1CCCN(C)CCOC Show InChI InChI=1S/C16H31N5O/c1-5-6-9-18-15-14(13(2)19-16(17)20-15)8-7-10-21(3)11-12-22-4/h5-12H2,1-4H3,(H3,17,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	203	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR8 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236161 (CHEMBL4078964) Show SMILES CCCCNc1nc(N)nc(C)c1CC Show InChI InChI=1S/C11H20N4/c1-4-6-7-13-10-9(5-2)8(3)14-11(12)15-10/h4-7H2,1-3H3,(H3,12,13,14,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.27E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50236179 (CHEMBL4092273) Show SMILES CCCCNc1nc(N)nc(C)c1CCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C22H34N6/c1-3-4-12-24-21-20(18(2)25-22(23)26-21)11-8-13-27-14-16-28(17-15-27)19-9-6-5-7-10-19/h5-7,9-10H,3-4,8,11-17H2,1-2H3,(H3,23,24,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	92	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR8 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50236191 (CHEMBL4083025) Show SMILES CCCCNc1nc(N)nc(C)c1CCCN1CCSCC1 Show InChI InChI=1S/C16H29N5S/c1-3-4-7-18-15-14(13(2)19-16(17)20-15)6-5-8-21-9-11-22-12-10-21/h3-12H2,1-2H3,(H3,17,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	167	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR8 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50236178 (CHEMBL4061978) Show SMILES CCCCNc1nc(N)nc(C)c1CCCN1CCCCC1 Show InChI InChI=1S/C17H31N5/c1-3-4-10-19-16-15(14(2)20-17(18)21-16)9-8-13-22-11-6-5-7-12-22/h3-13H2,1-2H3,(H3,18,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	133	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR8 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50236188 (CHEMBL4071479) Show SMILES CCCCNc1nc(N)nc(C)c1CCCN1CCN(C)CC1 Show InChI InChI=1S/C17H32N6/c1-4-5-8-19-16-15(14(2)20-17(18)21-16)7-6-9-23-12-10-22(3)11-13-23/h4-13H2,1-3H3,(H3,18,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	179	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR8 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50236151 (CHEMBL4078632) Show SMILES CCCCNc1nc(N)nc(C)c1CCCN(C)C Show InChI InChI=1S/C14H27N5/c1-5-6-9-16-13-12(8-7-10-19(3)4)11(2)17-14(15)18-13/h5-10H2,1-4H3,(H3,15,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	126	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR8 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236178 (CHEMBL4061978) Show SMILES CCCCNc1nc(N)nc(C)c1CCCN1CCCCC1 Show InChI InChI=1S/C17H31N5/c1-3-4-10-19-16-15(14(2)20-17(18)21-16)9-8-13-22-11-6-5-7-12-22/h3-13H2,1-2H3,(H3,18,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	710	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236162 (CHEMBL4103230) Show SMILES CCCCNc1nc(N)nc(C)c1CCCC Show InChI InChI=1S/C13H24N4/c1-4-6-8-11-10(3)16-13(14)17-12(11)15-9-7-5-2/h4-9H2,1-3H3,(H3,14,15,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	590	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236174 (CHEMBL4062920) Show SMILES CCCCNc1nc(N)nc(C)c1CCC(C)(C)O Show InChI InChI=1S/C14H26N4O/c1-5-6-9-16-12-11(7-8-14(3,4)19)10(2)17-13(15)18-12/h19H,5-9H2,1-4H3,(H3,15,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.26E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50236143 (CHEMBL4101270) Show SMILES CCCCNc1nc(N)nc(C)c1CCCn1cncn1 Show InChI InChI=1S/C14H23N7/c1-3-4-7-17-13-12(11(2)19-14(15)20-13)6-5-8-21-10-16-9-18-21/h9-10H,3-8H2,1-2H3,(H3,15,17,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR8 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236157 (CHEMBL4063952) Show SMILES CCCCNc1nc(N)nc(C)c1CCCCN1CCOCC1 Show InChI InChI=1S/C17H31N5O/c1-3-4-8-19-16-15(14(2)20-17(18)21-16)7-5-6-9-22-10-12-23-13-11-22/h3-13H2,1-2H3,(H3,18,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236175 (CHEMBL4088953) Show SMILES CCCCNc1nc(N)nc(C)c1CCCN1CCCCCC1 Show InChI InChI=1S/C18H33N5/c1-3-4-11-20-17-16(15(2)21-18(19)22-17)10-9-14-23-12-7-5-6-8-13-23/h3-14H2,1-2H3,(H3,19,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	730	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236163 (CHEMBL4101040) Show SMILES CCCCCc1c(C)nc(N)nc1NCCCC Show InChI InChI=1S/C14H26N4/c1-4-6-8-9-12-11(3)17-14(15)18-13(12)16-10-7-5-2/h4-10H2,1-3H3,(H3,15,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	510	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236145 (CHEMBL4103710) Show SMILES CCCCNc1nc(N)nc(C)c1CCCc1ccccc1 Show InChI InChI=1S/C18H26N4/c1-3-4-13-20-17-16(14(2)21-18(19)22-17)12-8-11-15-9-6-5-7-10-15/h5-7,9-10H,3-4,8,11-13H2,1-2H3,(H3,19,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	194	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236146 (CHEMBL4085784) Show SMILES CCCCNc1nc(N)nc(C)c1CCCCc1ccccc1 Show InChI InChI=1S/C19H28N4/c1-3-4-14-21-18-17(15(2)22-19(20)23-18)13-9-8-12-16-10-6-5-7-11-16/h5-7,10-11H,3-4,8-9,12-14H2,1-2H3,(H3,20,21,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	262	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236143 (CHEMBL4101270) Show SMILES CCCCNc1nc(N)nc(C)c1CCCn1cncn1 Show InChI InChI=1S/C14H23N7/c1-3-4-7-17-13-12(11(2)19-14(15)20-13)6-5-8-21-10-16-9-18-21/h9-10H,3-8H2,1-2H3,(H3,15,17,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.16E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50236144 (CHEMBL4089935) Show SMILES CCCCNc1nc(N)nc(C)c1CCc1ccccc1 Show InChI InChI=1S/C17H24N4/c1-3-4-12-19-16-15(13(2)20-17(18)21-16)11-10-14-8-6-5-7-9-14/h5-9H,3-4,10-12H2,1-2H3,(H3,18,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.19E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR8 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50236145 (CHEMBL4103710) Show SMILES CCCCNc1nc(N)nc(C)c1CCCc1ccccc1 Show InChI InChI=1S/C18H26N4/c1-3-4-13-20-17-16(14(2)21-18(19)22-17)12-8-11-15-9-6-5-7-10-15/h5-7,9-10H,3-4,8,11-13H2,1-2H3,(H3,19,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	749	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR8 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50236146 (CHEMBL4085784) Show SMILES CCCCNc1nc(N)nc(C)c1CCCCc1ccccc1 Show InChI InChI=1S/C19H28N4/c1-3-4-14-21-18-17(15(2)22-19(20)23-18)13-9-8-12-16-10-6-5-7-11-16/h5-7,10-11H,3-4,8-9,12-14H2,1-2H3,(H3,20,21,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	857	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR8 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50236147 (CHEMBL4095966) Show SMILES CCCCNc1nc(N)nc(C)c1CCCCCc1ccccc1 Show InChI InChI=1S/C20H30N4/c1-3-4-15-22-19-18(16(2)23-20(21)24-19)14-10-6-9-13-17-11-7-5-8-12-17/h5,7-8,11-12H,3-4,6,9-10,13-15H2,1-2H3,(H3,21,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	830	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR8 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236148 (CHEMBL4065927) Show SMILES CCCCNc1nc(N)nc(C)c1CCCn1ccc2ccccc12 Show InChI InChI=1S/C20H27N5/c1-3-4-12-22-19-17(15(2)23-20(21)24-19)9-7-13-25-14-11-16-8-5-6-10-18(16)25/h5-6,8,10-11,14H,3-4,7,9,12-13H2,1-2H3,(H3,21,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236149 (CHEMBL4093530) Show SMILES CCCCNc1nc(N)nc(C)c1CCCn1c(C)nc2ccccc12 Show InChI InChI=1S/C20H28N6/c1-4-5-12-22-19-16(14(2)23-20(21)25-19)9-8-13-26-15(3)24-17-10-6-7-11-18(17)26/h6-7,10-11H,4-5,8-9,12-13H2,1-3H3,(H3,21,22,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	379	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236151 (CHEMBL4078632) Show SMILES CCCCNc1nc(N)nc(C)c1CCCN(C)C Show InChI InChI=1S/C14H27N5/c1-5-6-9-16-13-12(8-7-10-19(3)4)11(2)17-14(15)18-13/h5-10H2,1-4H3,(H3,15,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	958	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236153 (CHEMBL4104376) Show SMILES Cl.Cl.Cl.CCCCNc1nc(N)nc(C)c1CCCN1CCNCC1 Show InChI InChI=1S/C16H30N6/c1-3-4-7-19-15-14(13(2)20-16(17)21-15)6-5-10-22-11-8-18-9-12-22/h18H,3-12H2,1-2H3,(H3,17,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.64E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50236154 (CHEMBL4096648) Show SMILES CCCCNc1nc(N)nc(C)c1CCCN(CC)CC Show InChI InChI=1S/C16H31N5/c1-5-8-11-18-15-14(13(4)19-16(17)20-15)10-9-12-21(6-2)7-3/h5-12H2,1-4H3,(H3,17,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	254	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR8 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair

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