Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277097 ((S) or (R)-4-(2,4- difluorophenyl)-8- methyl-7-{[1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277085 (US10072003, Example 1-5A | US10072003, Example 1-5...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277201 (4-(2-chloro-4-fluorophenyl)-7- [(2-methoxypyridin-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277130 (4-(2,4-difluorophenyl)-7-{[6- (trifluoromethyl)pyr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277097 ((S) or (R)-4-(2,4- difluorophenyl)-8- methyl-7-{[1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277189 (4-(4-chloro-2,6-difluorophenyl)-7-{[2- (trifluorom...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277199 (4-(2-fluoro-4-methoxyphenyl)-7- [(2-methoxypyridin...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277183 (4-(4-chloro-2-fluorophenyl)-7-{[2- (trifluoromethy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277100 (7-[(1-tert-butyl-1H-1,2,3- triazol-5-yl)methyl]-4-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277178 (4-(4-chloro-2-fluorophenyl)-7-[(2- methoxypyrimidi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277085 (US10072003, Example 1-5A | US10072003, Example 1-5...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277114 (4-(2,4-difluorophenyl)-7-[(4-methyl-1,2,5- oxadiaz...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277190 (4-(4-fluorophenyl)-7-{[6- (trifluoromethyl)pyrimid...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277198 (US10072003, Example 13-1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277175 (4-(4-chloro-2-fluorophenyl)-7-{[3-(1- methylethyl)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277090 (4-(2,4-difluorophenyl)-7- {[1-(1-methylethyl)-1H- ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277119 (7-{[2-(difluoromethoxy)pyridin-4- yl]methyl}-4-[1-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277089 (4-(4-chloro-2- fluorophenyl)-7-[(1- methyl-1H-pyra...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277104 ((S) or (R)-4-(4-chloro-2- fluorophenyl)-7-[(6,6- d...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277137 (US10072003, Example 3-2A | US10072003, Example 3-2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277171 (4-(4-chloro-2-fluorophenyl)-7-[(5-methyl- 1,2,4-ox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277094 (4-(2-fluoro-4- methylphenyl)-7-{[1-(1- methylethyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277166 (US10072003, Example 8-2A | US10072003, Example 8-2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277192 (4-(4-chloro-2-fluorophenyl)-7-{[6- (trifluoromethy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277118 (4-(2-chloro-4-fluorophenyl)-7-{[2- (difluoromethox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.04E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277116 (7-[(2-cyclopropylpyridin-4-yl)methyl]-4-[1- (diflu...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277127 (4-(4-chloro-2,6-difluorophenyl)-7-{[1- (difluorome...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277137 (US10072003, Example 3-2A | US10072003, Example 3-2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277166 (US10072003, Example 8-2A | US10072003, Example 8-2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277176 (4-(4-chloro-2-fluorophenyl)-7-[(4- methoxypyrimidi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.17E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277155 (US10072003, Example 6-1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.17E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277188 (4-(2-fluorophenyl)-7-{[2- (trifluoromethyl)pyrimid...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.18E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277179 (4-(4-chloro-2-fluorophenyl)-7-(pyridin-3- ylmethyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277101 ((S) or (R)-4-(4-chloro-2- fluorophenyl)-7-(((S) or...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.23E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277164 (US10072003, Example 8-1A | US10072003, Example 8-1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.27E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277174 (4-(4-chloro-2-fluorophenyl)-7-[(3-methyl- 1,2,4-ox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.27E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277164 (US10072003, Example 8-1A | US10072003, Example 8-1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.27E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277147 ((S) or (R)-4-(3- methylpiperidin-1-yl)-7- ((2- (tr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277194 (4-(6-azaspiro[2.5]oct-6-yl)-7-{[2- (trifluoromethy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277133 (4-(2,4-difluorophenyl)-7-[(4- methylisoxazol-3-yl)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277102 ((S) or (R)-8-methyl-7- {[1-(1-methylethyl)-1H- pyr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277186 (7-{[2-(trifluoromethyl)pyrimidin-4- yl]methyl}-4-(...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277088 (4-(2,4-difluorophenyl)-7- [(1,3-dimethyl-1H- pyraz...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.38E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277099 (4-(4-chloro-2- fluorophenyl)-7-[(1- methyl-1H-imid...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.41E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277172 (4-(4-chloro-2-fluorophenyl)-7-[(2- methoxypyrimidi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.42E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277087 (4-(2,4-difluorophenyl)-7- [(1-methyl-1H-pyrazol-5-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.45E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277180 (4-(4-chloro-2-fluorophenyl)-7-[(1-methyl- 1H-pyraz...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277106 (US10072003, Example 1-23A | US10072003, Example 1-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.47E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277200 (4-(4-chloro-2-fluorophenyl)-7- [(2-methoxypyridin-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM277149 ((S) or (R)-4-(3- fluoropiperidin-1-yl)-7-((2- (tri...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.73E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon... | US Patent US10072003 (2018) BindingDB Entry DOI: 10.7270/Q23R0VXK | |||||||||||
More data for this Ligand-Target Pair |
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