Compile Data Set for Download or QSAR

Found 48 hits Enz. Inhib. hit(s) with all data for entry = 6446   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin S (Homo sapiens (Human))	BDBM129694 (US8802665, 27) Show SMILES Clc1ccccc1S(=O)(=O)[C@@H]1C[C@H](N(C1)C(=O)C1(CC1)N1CCSCC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C23H27ClN4O4S2/c24-17-3-1-2-4-19(17)34(31,32)16-13-18(20(29)26-22(15-25)5-6-22)28(14-16)21(30)23(7-8-23)27-9-11-33-12-10-27/h1-4,16,18H,5-14H2,(H,26,29)/t16-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129710 (US8802665, 43) Show SMILES Clc1cccc(c1)S(=O)(=O)[C@@H]1C[C@H](N(C1)C(=O)C1(CC1)N1CCCCC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C24H29ClN4O4S/c25-17-5-4-6-18(13-17)34(32,33)19-14-20(21(30)27-23(16-26)7-8-23)29(15-19)22(31)24(9-10-24)28-11-2-1-3-12-28/h4-6,13,19-20H,1-3,7-12,14-15H2,(H,27,30)/t19-,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129713 (US8802665, 46) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)[C@@H]1C[C@H](N(C1)C(=O)C1(CC1)N1CCCCC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C25H29F3N4O4S/c26-25(27,28)17-5-4-6-18(13-17)37(35,36)19-14-20(21(33)30-23(16-29)7-8-23)32(15-19)22(34)24(9-10-24)31-11-2-1-3-12-31/h4-6,13,19-20H,1-3,7-12,14-15H2,(H,30,33)/t19-,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129693 (US8802665, 26) Show SMILES CC1CCCN(C1)C1(CC1)C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccccc1Cl |r| Show InChI InChI=1S/C25H31ClN4O4S/c1-17-5-4-12-29(14-17)25(10-11-25)23(32)30-15-18(35(33,34)21-7-3-2-6-19(21)26)13-20(30)22(31)28-24(16-27)8-9-24/h2-3,6-7,17-18,20H,4-5,8-15H2,1H3,(H,28,31)/t17?,18-,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129709 (US8802665, 42) Show SMILES Fc1ccc(c(Cl)c1)S(=O)(=O)[C@@H]1C[C@H](N(C1)C(=O)C1(CC1)N1CCCCC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C24H28ClFN4O4S/c25-18-12-16(26)4-5-20(18)35(33,34)17-13-19(21(31)28-23(15-27)6-7-23)30(14-17)22(32)24(8-9-24)29-10-2-1-3-11-29/h4-5,12,17,19H,1-3,6-11,13-14H2,(H,28,31)/t17-,19+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129711 (US8802665, 44) Show SMILES Cc1ccc(cc1)S(=O)(=O)[C@@H]1C[C@H](N(C1)C(=O)C1(CC1)N1CCCCC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C25H32N4O4S/c1-18-5-7-19(8-6-18)34(32,33)20-15-21(22(30)27-24(17-26)9-10-24)29(16-20)23(31)25(11-12-25)28-13-3-2-4-14-28/h5-8,20-21H,2-4,9-16H2,1H3,(H,27,30)/t20-,21+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129692 (US8802665, 25) Show SMILES Clc1ccccc1S(=O)(=O)[C@@H]1C[C@H](N(C1)C(=O)C1(CC1)N1CCCCC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C24H29ClN4O4S/c25-18-6-2-3-7-20(18)34(32,33)17-14-19(21(30)27-23(16-26)8-9-23)29(15-17)22(31)24(10-11-24)28-12-4-1-5-13-28/h2-3,6-7,17,19H,1,4-5,8-15H2,(H,27,30)/t17-,19+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129707 (US8802665, 40) Show SMILES Clc1ccccc1S(=O)(=O)[C@@H]1C[C@H](N(C1)C(=O)C1(CC1)N1CCCCCC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C25H31ClN4O4S/c26-19-7-3-4-8-21(19)35(33,34)18-15-20(22(31)28-24(17-27)9-10-24)30(16-18)23(32)25(11-12-25)29-13-5-1-2-6-14-29/h3-4,7-8,18,20H,1-2,5-6,9-16H2,(H,28,31)/t18-,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129705 (US8802665, 38) Show SMILES CC1CCN(CC1)C1(CC1)C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccccc1Cl |r| Show InChI InChI=1S/C25H31ClN4O4S/c1-17-6-12-29(13-7-17)25(10-11-25)23(32)30-15-18(35(33,34)21-5-3-2-4-19(21)26)14-20(30)22(31)28-24(16-27)8-9-24/h2-5,17-18,20H,6-15H2,1H3,(H,28,31)/t18-,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129712 (US8802665, 45) Show SMILES FC(F)(F)Oc1ccccc1S(=O)(=O)[C@@H]1C[C@H](N(C1)C(=O)C1(CC1)N1CCCCC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C25H29F3N4O5S/c26-25(27,28)37-19-6-2-3-7-20(19)38(35,36)17-14-18(21(33)30-23(16-29)8-9-23)32(15-17)22(34)24(10-11-24)31-12-4-1-5-13-31/h2-3,6-7,17-18H,1,4-5,8-15H2,(H,30,33)/t17-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129714 (US8802665, 47) Show SMILES Clc1ccc(cc1)S(=O)(=O)[C@@H]1C[C@H](N(C1)C(=O)C1(CC1)N1CCCCC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C24H29ClN4O4S/c25-17-4-6-18(7-5-17)34(32,33)19-14-20(21(30)27-23(16-26)8-9-23)29(15-19)22(31)24(10-11-24)28-12-2-1-3-13-28/h4-7,19-20H,1-3,8-15H2,(H,27,30)/t19-,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129706 (US8802665, 39) Show SMILES Clc1ccccc1S(=O)(=O)[C@@H]1C[C@H](N(C1)C(=O)C1(CC1)N1CCOCC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C23H27ClN4O5S/c24-17-3-1-2-4-19(17)34(31,32)16-13-18(20(29)26-22(15-25)5-6-22)28(14-16)21(30)23(7-8-23)27-9-11-33-12-10-27/h1-4,16,18H,5-14H2,(H,26,29)/t16-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129672 (US8802665, 5) Show SMILES Clc1ccccc1S(=O)(=O)[C@@H]1C[C@H](N(C1)C(=O)C1CCN1C1CCOCC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C24H29ClN4O5S/c25-18-3-1-2-4-21(18)35(32,33)17-13-20(22(30)27-24(15-26)8-9-24)29(14-17)23(31)19-5-10-28(19)16-6-11-34-12-7-16/h1-4,16-17,19-20H,5-14H2,(H,27,30)/t17-,19?,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129671 (US8802665, 4) Show SMILES Cc1nsc(n1)N1CCC(CC1)N1CCC1C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccccc1Cl |r| Show InChI InChI=1S/C27H32ClN7O4S2/c1-17-30-26(40-32-17)33-11-6-18(7-12-33)34-13-8-21(34)25(37)35-15-19(41(38,39)23-5-3-2-4-20(23)28)14-22(35)24(36)31-27(16-29)9-10-27/h2-5,18-19,21-22H,6-15H2,1H3,(H,31,36)/t19-,21?,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129708 (US8802665, 41) Show SMILES CC1CCCCN1C1(CC1)C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccccc1Cl |r| Show InChI InChI=1S/C25H31ClN4O4S/c1-17-6-4-5-13-30(17)25(11-12-25)23(32)29-15-18(35(33,34)21-8-3-2-7-19(21)26)14-20(29)22(31)28-24(16-27)9-10-24/h2-3,7-8,17-18,20H,4-6,9-15H2,1H3,(H,28,31)/t17?,18-,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129669 (US8802665, 2) Show SMILES FC1(F)CCC(CC1)N1CCC1C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccccc1Cl |r| Show InChI InChI=1S/C25H29ClF2N4O4S/c26-18-3-1-2-4-21(18)37(35,36)17-13-20(22(33)30-24(15-29)10-11-24)32(14-17)23(34)19-7-12-31(19)16-5-8-25(27,28)9-6-16/h1-4,16-17,19-20H,5-14H2,(H,30,33)/t17-,19?,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129695 (US8802665, 28) Show SMILES Clc1ccccc1S(=O)(=O)[C@@H]1C[C@H](N(C1)C(=O)C1(CC1)N1CCCC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C23H27ClN4O4S/c24-17-5-1-2-6-19(17)33(31,32)16-13-18(20(29)26-22(15-25)7-8-22)28(14-16)21(30)23(9-10-23)27-11-3-4-12-27/h1-2,5-6,16,18H,3-4,7-14H2,(H,26,29)/t16-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129704 (US8802665, 37) Show SMILES Clc1ccccc1S(=O)(=O)[C@@H]1C[C@H](N(C1)C(=O)C1(CC1)N1CCC(CC1)c1ccccc1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C30H33ClN4O4S/c31-24-8-4-5-9-26(24)40(38,39)23-18-25(27(36)33-29(20-32)12-13-29)35(19-23)28(37)30(14-15-30)34-16-10-22(11-17-34)21-6-2-1-3-7-21/h1-9,22-23,25H,10-19H2,(H,33,36)/t23-,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129673 (US8802665, 6) Show SMILES CC(=O)N1CCC(CC1)N1CCC1C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccccc1Cl |r| Show InChI InChI=1S/C26H32ClN5O5S/c1-17(33)30-11-6-18(7-12-30)31-13-8-21(31)25(35)32-15-19(38(36,37)23-5-3-2-4-20(23)27)14-22(32)24(34)29-26(16-28)9-10-26/h2-5,18-19,21-22H,6-15H2,1H3,(H,29,34)/t19-,21?,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129701 (US8802665, 34) Show SMILES Clc1ccccc1S(=O)(=O)[C@@H]1C[C@H](N(C1)C(=O)C1(CC1)N1CCN(CC1)C=O)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C24H28ClN5O5S/c25-18-3-1-2-4-20(18)36(34,35)17-13-19(21(32)27-23(15-26)5-6-23)30(14-17)22(33)24(7-8-24)29-11-9-28(16-31)10-12-29/h1-4,16-17,19H,5-14H2,(H,27,32)/t17-,19+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129687 (US8802665, 20) Show SMILES CCOC(=O)N1CCC(CC1)N1CCC1C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccc(C)cc1 |r| Show InChI InChI=1S/C28H37N5O6S/c1-3-39-27(36)31-13-8-20(9-14-31)32-15-10-23(32)26(35)33-17-22(40(37,38)21-6-4-19(2)5-7-21)16-24(33)25(34)30-28(18-29)11-12-28/h4-7,20,22-24H,3,8-17H2,1-2H3,(H,30,34)/t22-,23?,24+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129681 (US8802665, 14) Show SMILES CCOC(=O)N1CCC(CC1)N1CCC1C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccc(F)cc1Cl |r| Show InChI InChI=1S/C27H33ClFN5O6S/c1-2-40-26(37)32-10-5-18(6-11-32)33-12-7-21(33)25(36)34-15-19(14-22(34)24(35)31-27(16-30)8-9-27)41(38,39)23-4-3-17(29)13-20(23)28/h3-4,13,18-19,21-22H,2,5-12,14-15H2,1H3,(H,31,35)/t19-,21?,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129691 (US8802665, 24) Show SMILES CCOC(=O)N1CCC(CC1)N1CCC1C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C28H34F3N5O6S/c1-2-42-26(39)34-11-6-19(7-12-34)35-13-8-22(35)25(38)36-16-21(15-23(36)24(37)33-27(17-32)9-10-27)43(40,41)20-5-3-4-18(14-20)28(29,30)31/h3-5,14,19,21-23H,2,6-13,15-16H2,1H3,(H,33,37)/t21-,22?,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129678 (US8802665, 11) Show SMILES CCOC(=O)N1CCC(CC1)N1CCC1C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccccc1Cl |r| Show InChI InChI=1S/C27H34ClN5O6S/c1-2-39-26(36)31-12-7-18(8-13-31)32-14-9-21(32)25(35)33-16-19(40(37,38)23-6-4-3-5-20(23)28)15-22(33)24(34)30-27(17-29)10-11-27/h3-6,18-19,21-22H,2,7-16H2,1H3,(H,30,34)/t19-,21?,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129668 (US8802665, 1) Show SMILES Clc1ccccc1S(=O)(=O)[C@@H]1C[C@H](N(C1)C(=O)C1CCN1C1CCCCC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C25H31ClN4O4S/c26-19-8-4-5-9-22(19)35(33,34)18-14-21(23(31)28-25(16-27)11-12-25)30(15-18)24(32)20-10-13-29(20)17-6-2-1-3-7-17/h4-5,8-9,17-18,20-21H,1-3,6-7,10-15H2,(H,28,31)/t18-,20?,21+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129686 (US8802665, 19) Show SMILES CCOC(=O)N1CCC(CC1)N1CCC1C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C27H34ClN5O6S/c1-2-39-26(36)31-11-6-19(7-12-31)32-13-8-22(32)25(35)33-16-21(40(37,38)20-5-3-4-18(28)14-20)15-23(33)24(34)30-27(17-29)9-10-27/h3-5,14,19,21-23H,2,6-13,15-16H2,1H3,(H,30,34)/t21-,22?,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129676 (US8802665, 9) Show SMILES Clc1ccccc1S(=O)(=O)[C@@H]1C[C@H](N(C1)C(=O)C1CCN1C1CCCC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C24H29ClN4O4S/c25-18-7-3-4-8-21(18)34(32,33)17-13-20(22(30)27-24(15-26)10-11-24)29(14-17)23(31)19-9-12-28(19)16-5-1-2-6-16/h3-4,7-8,16-17,19-20H,1-2,5-6,9-14H2,(H,27,30)/t17-,19?,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129698 (US8802665, 31) Show SMILES CC(=O)N1CCN(CC1)C1(CC1)C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccccc1Cl |r| Show InChI InChI=1S/C25H30ClN5O5S/c1-17(32)29-10-12-30(13-11-29)25(8-9-25)23(34)31-15-18(37(35,36)21-5-3-2-4-19(21)26)14-20(31)22(33)28-24(16-27)6-7-24/h2-5,18,20H,6-15H2,1H3,(H,28,33)/t18-,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129677 (US8802665, 10) Show SMILES Clc1ccccc1S(=O)(=O)[C@@H]1C[C@H](N(C1)C(=O)C1CCN1C1CCSCC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C24H29ClN4O4S2/c25-18-3-1-2-4-21(18)35(32,33)17-13-20(22(30)27-24(15-26)8-9-24)29(14-17)23(31)19-5-10-28(19)16-6-11-34-12-7-16/h1-4,16-17,19-20H,5-14H2,(H,27,30)/t17-,19?,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129715 (US8802665, 48) Show SMILES CC1(C)CCCN(C1)C1(CC1)C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccccc1Cl |r| Show InChI InChI=1S/C26H33ClN4O4S/c1-24(2)8-5-13-30(17-24)26(11-12-26)23(33)31-15-18(36(34,35)21-7-4-3-6-19(21)27)14-20(31)22(32)29-25(16-28)9-10-25/h3-4,6-7,18,20H,5,8-15,17H2,1-2H3,(H,29,32)/t18-,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129696 (US8802665, 29) Show SMILES CC(C)(C)OC(=O)N1CCN(CC1)C1(CC1)C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccccc1Cl |r| Show InChI InChI=1S/C28H36ClN5O6S/c1-26(2,3)40-25(37)32-12-14-33(15-13-32)28(10-11-28)24(36)34-17-19(41(38,39)22-7-5-4-6-20(22)29)16-21(34)23(35)31-27(18-30)8-9-27/h4-7,19,21H,8-17H2,1-3H3,(H,31,35)/t19-,21+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129699 (US8802665, 32) Show SMILES CS(=O)(=O)N1CCN(CC1)C1(CC1)C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccccc1Cl |r| Show InChI InChI=1S/C24H30ClN5O6S2/c1-37(33,34)29-12-10-28(11-13-29)24(8-9-24)22(32)30-15-17(38(35,36)20-5-3-2-4-18(20)25)14-19(30)21(31)27-23(16-26)6-7-23/h2-5,17,19H,6-15H2,1H3,(H,27,31)/t17-,19+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129675 (US8802665, 8) Show SMILES CC1(C)CC(CCO1)N1CCC1C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccccc1Cl |r| Show InChI InChI=1S/C26H33ClN4O5S/c1-25(2)14-17(8-12-36-25)30-11-7-20(30)24(33)31-15-18(37(34,35)22-6-4-3-5-19(22)27)13-21(31)23(32)29-26(16-28)9-10-26/h3-6,17-18,20-21H,7-15H2,1-2H3,(H,29,32)/t17?,18-,20?,21+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129700 (US8802665, 33) Show SMILES COC(=O)N1CCN(CC1)C1(CC1)C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccccc1Cl |r| Show InChI InChI=1S/C25H30ClN5O6S/c1-37-23(34)29-10-12-30(13-11-29)25(8-9-25)22(33)31-15-17(38(35,36)20-5-3-2-4-18(20)26)14-19(31)21(32)28-24(16-27)6-7-24/h2-5,17,19H,6-15H2,1H3,(H,28,32)/t17-,19+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129679 (US8802665, 12) Show SMILES CS(=O)(=O)N1CCC(CC1)N1CCC1C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccccc1Cl |r| Show InChI InChI=1S/C25H32ClN5O6S2/c1-38(34,35)29-11-6-17(7-12-29)30-13-8-20(30)24(33)31-15-18(39(36,37)22-5-3-2-4-19(22)26)14-21(31)23(32)28-25(16-27)9-10-25/h2-5,17-18,20-21H,6-15H2,1H3,(H,28,32)/t18-,20?,21+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129689 (US8802665, 22) Show SMILES CCOC(=O)N1CCC(CC1)N1CCC1C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C27H34ClN5O6S/c1-2-39-26(36)31-12-7-19(8-13-31)32-14-9-22(32)25(35)33-16-21(40(37,38)20-5-3-18(28)4-6-20)15-23(33)24(34)30-27(17-29)10-11-27/h3-6,19,21-23H,2,7-16H2,1H3,(H,30,34)/t21-,22?,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.80	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129702 (US8802665, 35) Show SMILES FC(F)(F)C(=O)N1CCN(CC1)C1(CC1)C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccccc1Cl |r| Show InChI InChI=1S/C25H27ClF3N5O5S/c26-17-3-1-2-4-19(17)40(38,39)16-13-18(20(35)31-23(15-30)5-6-23)34(14-16)21(36)24(7-8-24)33-11-9-32(10-12-33)22(37)25(27,28)29/h1-4,16,18H,5-14H2,(H,31,35)/t16-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.70	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129670 (US8802665, 3) Show SMILES CC1(C)CCC(CC1)N1CCC1C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccccc1Cl |r| Show InChI InChI=1S/C27H35ClN4O4S/c1-26(2)10-7-18(8-11-26)31-14-9-21(31)25(34)32-16-19(37(35,36)23-6-4-3-5-20(23)28)15-22(32)24(33)30-27(17-29)12-13-27/h3-6,18-19,21-22H,7-16H2,1-2H3,(H,30,33)/t19-,21?,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.80	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129674 (US8802665, 7) Show SMILES FC(F)(F)CN1CCC(CC1)N1CCC1C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccccc1Cl |r| Show InChI InChI=1S/C26H31ClF3N5O4S/c27-19-3-1-2-4-22(19)40(38,39)18-13-21(23(36)32-25(15-31)8-9-25)35(14-18)24(37)20-7-12-34(20)17-5-10-33(11-6-17)16-26(28,29)30/h1-4,17-18,20-21H,5-14,16H2,(H,32,36)/t18-,20?,21+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.90	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129690 (US8802665, 23) Show SMILES CCOC(=O)N1CCC(CC1)N1CCC1C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccccc1OC(F)(F)F |r| Show InChI InChI=1S/C28H34F3N5O7S/c1-2-42-26(39)34-12-7-18(8-13-34)35-14-9-20(35)25(38)36-16-19(15-21(36)24(37)33-27(17-32)10-11-27)44(40,41)23-6-4-3-5-22(23)43-28(29,30)31/h3-6,18-21H,2,7-16H2,1H3,(H,33,37)/t19-,20?,21+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.10	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129697 (US8802665, 30) Show SMILES Clc1ccccc1S(=O)(=O)[C@@H]1C[C@H](N(C1)C(=O)C1(CC1)N1CCNCC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C23H28ClN5O4S/c24-17-3-1-2-4-19(17)34(32,33)16-13-18(20(30)27-22(15-25)5-6-22)29(14-16)21(31)23(7-8-23)28-11-9-26-10-12-28/h1-4,16,18,26H,5-14H2,(H,27,30)/t16-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.20	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129703 (US8802665, 36) Show SMILES CCN1CCN(CC1)C1(CC1)C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccccc1Cl |r| Show InChI InChI=1S/C25H32ClN5O4S/c1-2-29-11-13-30(14-12-29)25(9-10-25)23(33)31-16-18(36(34,35)21-6-4-3-5-19(21)26)15-20(31)22(32)28-24(17-27)7-8-24/h3-6,18,20H,2,7-16H2,1H3,(H,28,32)/t18-,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.20	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129680 (US8802665, 13) Show SMILES CCOC(=O)N1CCC(CC1)N1CCC1C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)Sc1ccc(F)cc1Cl |r| Show InChI InChI=1S/C27H33ClFN5O4S/c1-2-38-26(37)32-10-5-18(6-11-32)33-12-7-21(33)25(36)34-15-19(39-23-4-3-17(29)13-20(23)28)14-22(34)24(35)31-27(16-30)8-9-27/h3-4,13,18-19,21-22H,2,5-12,14-15H2,1H3,(H,31,35)/t19-,21?,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.70	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129685 (US8802665, 18) Show SMILES CCOC(=O)N1CCC(CC1)N1CCC1C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)Sc1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C28H34F3N5O4S/c1-2-40-26(39)34-11-6-19(7-12-34)35-13-8-22(35)25(38)36-16-21(15-23(36)24(37)33-27(17-32)9-10-27)41-20-5-3-4-18(14-20)28(29,30)31/h3-5,14,19,21-23H,2,6-13,15-16H2,1H3,(H,33,37)/t21-,22?,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129688 (US8802665, 21) Show SMILES CCOC(=O)N1CCC(CC1)N1CCC1C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccccc1OC |r| Show InChI InChI=1S/C28H37N5O7S/c1-3-40-27(36)31-13-8-19(9-14-31)32-15-10-21(32)26(35)33-17-20(16-22(33)25(34)30-28(18-29)11-12-28)41(37,38)24-7-5-4-6-23(24)39-2/h4-7,19-22H,3,8-17H2,1-2H3,(H,30,34)/t20-,21?,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9.20	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129684 (US8802665, 17) Show SMILES CCOC(=O)N1CCC(CC1)N1CCC1C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)Sc1ccccc1OC(F)(F)F |r| Show InChI InChI=1S/C28H34F3N5O5S/c1-2-40-26(39)34-12-7-18(8-13-34)35-14-9-20(35)25(38)36-16-19(15-21(36)24(37)33-27(17-32)10-11-27)42-23-6-4-3-5-22(23)41-28(29,30)31/h3-6,18-21H,2,7-16H2,1H3,(H,33,37)/t19-,20?,21+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	65.5	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129682 (US8802665, 15) Show SMILES CCOC(=O)N1CCC(CC1)N1CCC1C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)Sc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C27H34ClN5O4S/c1-2-37-26(36)31-12-7-19(8-13-31)32-14-9-22(32)25(35)33-16-21(38-20-5-3-18(28)4-6-20)15-23(33)24(34)30-27(17-29)10-11-27/h3-6,19,21-23H,2,7-16H2,1H3,(H,30,34)/t21-,22?,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	121	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM129683 (US8802665, 16) Show SMILES CCOC(=O)N1CCC(CC1)N1CCC1C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)Sc1ccccc1OC |r| Show InChI InChI=1S/C28H37N5O5S/c1-3-38-27(36)31-13-8-19(9-14-31)32-15-10-21(32)26(35)33-17-20(39-24-7-5-4-6-23(24)37-2)16-22(33)25(34)30-28(18-29)11-12-28/h4-7,19-22H,3,8-17H2,1-2H3,(H,30,34)/t20-,21?,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.74E+3	n/a	n/a	n/a	n/a	6.5	n/a
Genentech, Inc. US Patent					Assay Description Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...				US Patent US8802665 (2014) BindingDB Entry DOI: 10.7270/Q2K64GR4
					More data for this Ligand-Target Pair