Compile Data Set for Download or QSAR

Found 77 hits Enz. Inhib. hit(s) with all data for entry = 6649   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor XI (Homo sapiens (Human))	BDBM47108 (US10487086, Example 10 | US11136327, Example 10 | ...) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](CCCCC(=O)Nc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair				3D Structure (crystal)
Coagulation factor XI (Homo sapiens (Human))	BDBM142885 (US10487086, Example I-278 | US11136327, Example I-...) Show SMILES COCCOC(=O)Nc1ccc2-c3nc([nH]c3C#N)[C@H](CCCC[C@@H](Nc2c1)C(=O)OC)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142896 (US10487086, Example 61 | US8940720, 61 | US9802939...) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](CCC(C)CCC(=O)Nc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142864 (US10487086, Example 90 | US11136327, Example 90 | ...) Show SMILES COC(=O)Nc1ccc-2c(NC(=O)CC\C=C\C[C@H](NC(=O)[C@H]3CC[C@H](CN)CC3)c3cc-2ccn3)c1 |r,wU:22.21,18.18,wD:25.25,t:15,(11.34,.5,;10,1.27,;8.67,.5,;8.67,-1.04,;7.34,1.27,;6,.5,;6,-1.04,;4.67,-1.81,;3.33,-1.04,;3.33,.5,;2,1.27,;2,2.81,;3.45,3.34,;.91,3.9,;-.62,4.12,;-1.71,3.03,;-1.31,1.54,;-2.4,.45,;-2,-1.04,;-3.33,-1.81,;-4.67,-1.04,;-4.67,.5,;-6,-1.81,;-6,-3.35,;-7.34,-4.12,;-8.67,-3.35,;-10,-4.12,;-11.34,-3.35,;-8.67,-1.81,;-7.34,-1.04,;-.67,-1.81,;.67,-1.04,;2,-1.81,;2,-3.35,;.67,-4.12,;-.67,-3.35,;4.67,1.27,)| Show InChI InChI=1S/C28H35N5O4/c1-37-28(36)31-21-11-12-22-20-13-14-30-25(15-20)23(5-3-2-4-6-26(34)32-24(22)16-21)33-27(35)19-9-7-18(17-29)8-10-19/h2-3,11-16,18-19,23H,4-10,17,29H2,1H3,(H,31,36)(H,32,34)(H,33,35)/b3-2+/t18-,19-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142865 (US10487086, Example 93 | US11136327, Example 93 | ...) Show SMILES COC(=O)Nc1ccc-2c(NC(=O)CC\C=C\CC(NC(=O)\C=C\c3cc(Cl)ccc3-n3cnnn3)c3cccc-2c3)c1 |t:15| Show InChI InChI=1S/C31H28ClN7O4/c1-43-31(42)34-24-12-13-25-20-6-5-7-21(16-20)26(8-3-2-4-9-29(40)36-27(25)18-24)35-30(41)15-10-22-17-23(32)11-14-28(22)39-19-33-37-38-39/h2-3,5-7,10-19,26H,4,8-9H2,1H3,(H,34,42)(H,35,41)(H,36,40)/b3-2+,15-10+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142866 (US10487086, Example 121 | US11136327, Example 121 ...) Show SMILES Clc1[nH]c2nc1-c1ccccc1NC(=O)OC\C=C\C[C@@H]2NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r,t:19| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142930 (US10487086, Example II-35 | US11136327, Example II...) Show SMILES COC(=O)Nc1ccc-2c(N[C@H](CCCC[C@H](NC(=O)\C=C\c3cc(Cl)ccc3-n3cnnn3)c3cc-2ccn3)C(=O)N2CCN(C)CC2)c1 |r| Show InChI InChI=1S/C35H39ClN10O4/c1-44-15-17-45(18-16-44)34(48)29-6-4-3-5-28(41-33(47)12-7-24-19-25(36)8-11-32(24)46-22-38-42-43-46)31-20-23(13-14-37-31)27-10-9-26(21-30(27)40-29)39-35(49)50-2/h7-14,19-22,28-29,40H,3-6,15-18H2,1-2H3,(H,39,49)(H,41,47)/b12-7+/t28-,29+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142897 (US10487086, Example I-4 | US11136327, Example I-4 ...) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](CCCCC(=O)Nc2c1)NC(=O)c1ccc(cc1)C(N)=N |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142898 (US10487086, Example I-5 | US11136327, Example I-5 ...) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](CCCCC(=O)Nc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1ccnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142904 (US11136327, Example I-21 | US8940720, I-21) Show SMILES COC(=O)Nc1ccc2-c3nc([nH]c3F)[C@H](CCCCC(=O)Nc2c1)NC(=O)c1c(F)cc2n(C)cnc2c1F |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142927 (US11136327, Example II-13 | US8940720, II-13 | US9...) Show SMILES COC(=O)Nc1ccc-2c(NC(CCCC[C@H](NC(=O)C3CC[C@H](CN)CC3)c3cc-2ccn3)C(F)(F)F)c1 |r,wU:16.16,wD:23.23,(11.38,-1.36,;10.29,-.28,;8.8,-.67,;8.41,-2.16,;7.72,.42,;6.23,.02,;5.83,-1.47,;4.34,-1.87,;3.25,-.78,;3.65,.71,;1.96,2.31,;1.96,3.85,;.62,4.62,;-.71,3.85,;-.71,2.31,;-2.05,1.54,;-2.05,,;-3.38,-.77,;-4.71,,;-4.71,1.54,;-6.05,-.77,;-6.05,-2.31,;-7.38,-3.08,;-8.71,-2.31,;-10.05,-3.08,;-10.05,-4.62,;-8.71,-.77,;-7.38,0,;-.71,-.77,;.78,-.37,;1.86,-1.46,;1.47,-2.95,;-.02,-3.35,;-1.11,-2.26,;3.29,4.62,;4.62,3.85,;3.29,6.16,;4.62,5.39,;5.14,1.11,)| Show InChI InChI=1S/C28H36F3N5O3/c1-39-27(38)34-20-10-11-21-19-12-13-33-24(14-19)22(36-26(37)18-8-6-17(16-32)7-9-18)4-2-3-5-25(28(29,30)31)35-23(21)15-20/h10-15,17-18,22,25,35H,2-9,16,32H2,1H3,(H,34,38)(H,36,37)/t17-,18?,22-,25?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142906 (US10487086, Example I-59 | US8940720, I-59) Show SMILES COC(=O)Nc1ccc2-c3nc([nH]c3Cl)[C@H](CCCC(C)C(=O)Nc2c1)NC(=O)c1c(F)cc2n(C)ccc2c1F |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142873 (US10487086, Example I-77 | US11136327, Example I-7...) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](CCCC[C@H](CO)Nc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142910 (US10487086, Example I-80 | US11136327, Example I-8...) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](CCCC[C@@H](Nc2c1)C(=O)N1CCCC1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142917 (US10487086, Example I-115 | US11136327, Example I-...) Show SMILES COC(=O)Nc1ccc2-c3nc([nH]c3C#N)[C@H](CCCCCNc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142919 (BDBM420091 | US11136327, Example I-124 | US8940720...) Show SMILES Clc1ccc(c(\C=C\C(=O)N[C@H]2CCCCCNc3cc(NC(=O)OC[C@H]4CCCO4)ccc3-c3c[nH]c2n3)c1)-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142876 (US10487086, Example I-134 | US11136327, Example I-...) Show SMILES COC(=O)Nc1ccc2-c3cnc(o3)[C@H](CCCCC(=O)Nc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI InChI=1S/C27H25ClN8O5/c1-40-27(39)31-18-8-9-19-21(13-18)33-24(37)5-3-2-4-20(26-29-14-23(19)41-26)32-25(38)11-6-16-12-17(28)7-10-22(16)36-15-30-34-35-36/h6-15,20H,2-5H2,1H3,(H,31,39)(H,32,38)(H,33,37)/b11-6+/t20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142920 (US8940720, I-151) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](C\C=C\CC(=O)Nc2c1)NC(=O)c1ccc2CNCCc2c1 |r,t:17| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142890 (US10487086, Example II-3 | US11136327, Example II-...) Show SMILES COC(=O)Nc1ccc-2c(NC(=O)CC\C=C\C[C@H](NC(=O)c3ccc(cc3)C(N)=N)c3cc-2ccn3)c1 |r,t:15| Show InChI InChI=1S/C28H28N6O4/c1-38-28(37)32-20-11-12-21-19-13-14-31-24(15-19)22(5-3-2-4-6-25(35)33-23(21)16-20)34-27(36)18-9-7-17(8-10-18)26(29)30/h2-3,7-16,22H,4-6H2,1H3,(H3,29,30)(H,32,37)(H,33,35)(H,34,36)/b3-2+/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142880 (US10487086, Example I-227 | US11136327, Example I-...) Show SMILES Fc1ccc2NC(=O)CC\C=C\C[C@H](NC(=O)\C=C\c3cc(Cl)ccc3-n3cnnn3)c3nc(c(Cl)[nH]3)-c2c1 |r,t:10| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142924 (US10487086, Example I-251 | US11136327, Example I-...) Show SMILES CCOC(=O)[C@H]1CCCC[C@H](NC(=O)\C=C\c2cc(Cl)ccc2-n2cnnn2)c2nc(c([nH]2)C#N)-c2ccc(NC(=O)OC)cc2N1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142889 (US10487086, Example I-311 | US11136327, Example I-...) Show SMILES COC(=O)Nc1ccc2-c3nc([nH]c3Cl)[C@H](C\C=C\CCC(=O)Nc2c1)NC(=O)\C=C\c1c(F)c(Cl)ccc1C(F)(F)F |r,t:18| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142895 (US10487086, Example II-62 | US11136327, Example II...) Show SMILES CCOC(=O)C1CCCCC(NC(=O)\C=C\c2cc(Cl)ccc2-n2cnnn2)c2cc(cc(=O)[nH]2)-c2ccc(NC(=O)OC)cc2N1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142860 (US10487086, Example 11 | US11136327, Example 11 | ...) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](CCCCCNc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142905 (US8940720, I-57) Show SMILES COC(=O)Nc1ccc2-c3nc([nH]c3Cl)[C@H](CCCC(C)C(=O)Nc2c1)NC(=O)c1c(F)cc2n(C)cnc2c1F |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142888 (US10487086, Example I-309 | US11136327, Example I-...) Show SMILES COC(=O)Nc1ccc2-c3nc([nH]c3Cl)[C@H](C\C=C\CCC(=O)Nc2c1)NC(=O)\C=C\c1cccc(Cl)c1 |r,t:18| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142883 (US10487086, Example I-268 | US11136327, Example I-...) Show SMILES COC(=O)Nc1ccc2-c3nc([nH]c3C#N)[C@H](CCCCCNc2c1)NC(=O)\C=C\c1cc(C)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142887 (US10487086, Example I-299 | US11136327, Example I-...) Show SMILES COC(=O)Nc1ccc2-c3nc([nH]c3C(=O)N(C)C)[C@H](CCCCCNc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142870 (US10487086, Example 138 | US11136327, Example 138 ...) Show SMILES Clc1ccc(c(\C=C\C(=O)N[C@H]2CCCCC(=O)Nc3cnccc3-c3ccnc2c3)c1)-n1cnnn1 |r| Show InChI InChI=1S/C26H23ClN8O2/c27-19-6-7-24(35-16-30-33-34-35)18(13-19)5-8-26(37)31-21-3-1-2-4-25(36)32-23-15-28-11-10-20(23)17-9-12-29-22(21)14-17/h5-16,21H,1-4H2,(H,31,37)(H,32,36)/b8-5+/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142921 (US8940720, I-152) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](C\C=C\CC(=O)Nc2c1)NC(=O)c1ccc2[C@H](N)CCCc2c1 |r,t:17| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142894 (US10487086, Example II-58 | US8940720, II-58 | US9...) Show SMILES COC(=O)Nc1ccc-2c(N[C@H](CCCC[C@H](NC(=O)\C=C\c3cc(Cl)ccc3-n3cnnn3)c3cncc-2c3)C(=O)NCc2ccccn2)c1 |r| Show InChI InChI=1S/C36H35ClN10O4/c1-51-36(50)42-27-11-12-29-24-16-25(20-38-19-24)30(44-34(48)14-9-23-17-26(37)10-13-33(23)47-22-41-45-46-47)7-2-3-8-31(43-32(29)18-27)35(49)40-21-28-6-4-5-15-39-28/h4-6,9-20,22,30-31,43H,2-3,7-8,21H2,1H3,(H,40,49)(H,42,50)(H,44,48)/b14-9+/t30-,31+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142892 (US10487086, Example II-10 | US11136327, Example II...) Show SMILES COC(=O)Nc1ccc-2c(NC(=O)CCCCC(NC(=O)\C=C\c3cc(Cl)ccc3-n3cnnn3)c3cc-2nc(C)n3)c1 Show InChI InChI=1S/C29H28ClN9O4/c1-17-32-24-15-25(33-17)22(35-28(41)12-7-18-13-19(30)8-11-26(18)39-16-31-37-38-39)5-3-4-6-27(40)36-23-14-20(9-10-21(23)24)34-29(42)43-2/h7-16,22H,3-6H2,1-2H3,(H,34,42)(H,35,41)(H,36,40)/b12-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142874 (US10487086, Example I-106 | US8940720, I-106) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](CCC=CC(=O)Nc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r,w:17.17| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142867 (US8940720, 122) Show SMILES Clc1ccc(c(\C=C\C(=O)N[C@H]2C\C=C\CCC(=O)Nc3ccccc3-c3nnc2o3)c1)-n1cnnn1 |r,w:15.14,t:13| Show InChI InChI=1S/C25H21ClN8O3/c26-17-11-12-21(34-15-27-32-33-34)16(14-17)10-13-23(36)29-20-8-2-1-3-9-22(35)28-19-7-5-4-6-18(19)24-30-31-25(20)37-24/h1-2,4-7,10-15,20H,3,8-9H2,(H,28,35)(H,29,36)/b2-1+,13-10+/t20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142875 (US10487086, Example I-107 | US11136327, Example I-...) Show SMILES COC(=O)Nc1ccc2-c3nc([nH]c3F)[C@H](CCCC\C=N\c2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r,t:21| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142858 (US10487086, Example 6 | US11136327, Example 6 | US...) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](CCCCCCc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142861 (US10487086, Example 19 | US11136327, Example 19 | ...) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](C\C=C/CS(=O)(=O)Nc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r,c:17| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	96	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142886 (US10487086, Example I-284 | US11136327, Example I-...) Show SMILES COC(=O)c1ccc2NC(=O)CC\C=C\C[C@H](NC(=O)\C=C\c3cc(Cl)ccc3-n3cnnn3)c3nc(c[nH]3)-c2c1 |r,t:13| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	102	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142891 (US10487086, Example II-4 | US11136327, Example II-...) Show SMILES COC(=O)Nc1ccc-2c(NC(=O)CCCC[C@H](NC(=O)c3c(F)cc(C)cc3F)c3cc-2ccn3)c1 |r| Show InChI InChI=1S/C27H26F2N4O4/c1-15-11-19(28)25(20(29)12-15)26(35)33-21-5-3-4-6-24(34)32-22-14-17(31-27(36)37-2)7-8-18(22)16-9-10-30-23(21)13-16/h7-14,21H,3-6H2,1-2H3,(H,31,36)(H,32,34)(H,33,35)/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	111	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142882 (US10487086, Example I-265 | US11136327, Example I-...) Show SMILES COC(=O)Nc1ccc2-c3nc([nH]c3C#N)[C@H](CCCCCNc2c1)NC(=O)\C=C\c1c(F)c(Cl)ccc1C(C)=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	133	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142871 (US10487086, Example 167 | US11136327, Example 167 ...) Show SMILES COC(=O)Nc1ccc-2c(NC(=O)C\C=C\CC(NC(=O)\C=C\c3cc(Cl)ccc3-n3cnnn3)c3cc-2nc(C)n3)c1 |t:14| Show InChI InChI=1S/C29H26ClN9O4/c1-17-32-24-15-25(33-17)22(35-28(41)12-7-18-13-19(30)8-11-26(18)39-16-31-37-38-39)5-3-4-6-27(40)36-23-14-20(9-10-21(23)24)34-29(42)43-2/h3-4,7-16,22H,5-6H2,1-2H3,(H,34,42)(H,35,41)(H,36,40)/b4-3+,12-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	157	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142877 (US8940720, I-136) Show SMILES Clc1ccc(c(\C=C\C(=O)N[C@H]2CCCCC(=O)Nc3cc4[nH]ncc4cc3-c3c[nH]c2n3)c1)-n1cnnn1 |r| Show InChI InChI=1S/C26H21ClN10O2/c27-17-6-7-23(37-14-30-35-36-37)15(9-17)5-8-25(39)31-19-3-1-2-4-24(38)32-21-11-20-16(12-29-34-20)10-18(21)22-13-28-26(19)33-22/h5-14,19H,1-4H2,(H,31,39)(H,32,38)/b8-5+,22-18-/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	183	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142869 (US10487086, Example 137 | US11136327, Example 137 ...) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](CC(O)C(O)CC(=O)Nc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	192	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142872 (US8940720, I-67) Show SMILES CCOC(=O)[C@H]1CCCC[C@H](NC(=O)\C=C\c2cc(Cl)ccc2-n2cnnn2)c2nc(c[nH]2)-c2ccc(NC(=O)OC)cc2N1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB US Patent	203	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair				3D Structure (crystal)
Coagulation factor XI (Homo sapiens (Human))	BDBM142900 (US10208068, Example 52 | US10487086, Example I-10 ...) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](CCCCC(=O)Nc2c1)NC(=O)c1cn(nn1)-c1cccc(Cl)c1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	217	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142859 (US10487086, Example 9 | US11136327, Example 9 | US...) Show SMILES COC(=O)Nc1ccc2-c3nc([nH]c3Cl)[C@H](CCCCCOc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	249	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142908 (US8940720, I-70) Show SMILES COC(=O)Nc1ccc2-c3nc([nH]c3C)[C@H](CCCCC(Nc2c1)C(F)(F)F)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142909 (US8940720, I-72) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](CCCCC(Nc2c1)C(F)F)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	289	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142916 (US10487086, Example I-114 | US11136327, Example I-...) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](CCCC(C)C(Nc2c1)C(N)=O)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	296	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142901 (US10487086, Example I-13 | US8940720, I-13) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](CCCCC(=O)Nc2c1)NC(=O)c1ccc2NCCCc2c1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	311	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...				US Patent US8940720 (2015) BindingDB Entry DOI: 10.7270/Q2BK1B20
					More data for this Ligand-Target Pair

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