Compile Data Set for Download or QSAR

Found 405 hits Enz. Inhib. hit(s) with all data for entry = 6999   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164684 (US9067871, 163) Show SMILES Cc1cccc(CC2C(CCc3ccc(OCCNS(=O)(=O)c4cn(C)cn4)cc23)N2CCCC2)c1 Show InChI InChI=1S/C28H36N4O3S/c1-21-6-5-7-22(16-21)17-26-25-18-24(10-8-23(25)9-11-27(26)32-13-3-4-14-32)35-15-12-30-36(33,34)28-19-31(2)20-29-28/h5-8,10,16,18-20,26-27,30H,3-4,9,11-15,17H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM60425 (US9067871, 169) Show SMILES CCCS(=O)(=O)NCc1ccc2CCC(N)[C@@H](Cc3ccccc3)c2c1 |r| Show InChI InChI=1S/C21H28N2O2S/c1-2-12-26(24,25)23-15-17-8-9-18-10-11-21(22)20(19(18)14-17)13-16-6-4-3-5-7-16/h3-9,14,20-21,23H,2,10-13,15,22H2,1H3/t20-,21?/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164755 (US9067871, 231) Show SMILES CN(CCCc1ccc2CCC(N)C(Cc3ccc(F)cc3)c2c1)S(=O)(=O)CC1CC1 Show InChI InChI=1S/C25H33FN2O2S/c1-28(31(29,30)17-20-4-5-20)14-2-3-18-6-9-21-10-13-25(27)24(23(21)15-18)16-19-7-11-22(26)12-8-19/h6-9,11-12,15,20,24-25H,2-5,10,13-14,16-17,27H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164763 (US9067871, 239 | US9067871, 240 | US9067871, 247) Show SMILES CNC1CCc2ccc(OCCNS(=O)(=O)CC3CC3)cc2C1Cc1cccc(F)c1 Show InChI InChI=1S/C24H31FN2O3S/c1-26-24-10-8-19-7-9-21(30-12-11-27-31(28,29)16-17-5-6-17)15-22(19)23(24)14-18-3-2-4-20(25)13-18/h2-4,7,9,13,15,17,23-24,26-27H,5-6,8,10-12,14,16H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164767 (US9067871, 243 | US9067871, 244 | US9067871, 245) Show SMILES CNC1CCc2ccc(OCCNS(=O)(=O)CC3CC3)cc2C1Cc1cc(F)cc(F)c1 Show InChI InChI=1S/C24H30F2N2O3S/c1-27-24-7-5-18-4-6-21(31-9-8-28-32(29,30)15-16-2-3-16)14-22(18)23(24)12-17-10-19(25)13-20(26)11-17/h4,6,10-11,13-14,16,23-24,27-28H,2-3,5,7-9,12,15H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164765 (US9067871, 241 | US9067871, 242 | US9067871, 246) Show SMILES CNC1CCc2ccc(OCCNS(=O)(=O)c3ccn(C)c3)cc2C1Cc1cc(F)cc(F)c1 Show InChI InChI=1S/C25H29F2N3O3S/c1-28-25-6-4-18-3-5-21(33-10-8-29-34(31,32)22-7-9-30(2)16-22)15-23(18)24(25)13-17-11-19(26)14-20(27)12-17/h3,5,7,9,11-12,14-16,24-25,28-29H,4,6,8,10,13H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164780 (US9067871, 252) Show SMILES O=S(=O)(NCc1ccc2CCC(C(Cc3ccccc3)c2c1)N1CCC1)c1ccccn1 Show InChI InChI=1S/C26H29N3O2S/c30-32(31,26-9-4-5-14-27-26)28-19-21-10-11-22-12-13-25(29-15-6-16-29)24(23(22)18-21)17-20-7-2-1-3-8-20/h1-5,7-11,14,18,24-25,28H,6,12-13,15-17,19H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164782 (US9067871, 254) Show SMILES O=S(=O)(NCc1ccc2CCC(C(Cc3ccccc3)c2c1)N1CCC1)c1cccs1 Show InChI InChI=1S/C25H28N2O2S2/c28-31(29,25-8-4-15-30-25)26-18-20-9-10-21-11-12-24(27-13-5-14-27)23(22(21)17-20)16-19-6-2-1-3-7-19/h1-4,6-10,15,17,23-24,26H,5,11-14,16,18H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164853 (US9067871, 307) Show SMILES CCNC1CCc2ccc(OCCNS(=O)(=O)CC3CC3)cc2C1Cc1cccc(Cl)c1 Show InChI InChI=1S/C25H33ClN2O3S/c1-2-27-25-11-9-20-8-10-22(31-13-12-28-32(29,30)17-18-6-7-18)16-23(20)24(25)15-19-4-3-5-21(26)14-19/h3-5,8,10,14,16,18,24-25,27-28H,2,6-7,9,11-13,15,17H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164870 (US9067871, 322) Show SMILES Cn1cc(cn1)S(=O)(=O)NCCOc1ccc2CCC(C(Cc3cccc(Cl)c3)c2c1)N1CCC1 Show InChI InChI=1S/C26H31ClN4O3S/c1-30-18-23(17-28-30)35(32,33)29-10-13-34-22-8-6-20-7-9-26(31-11-3-12-31)25(24(20)16-22)15-19-4-2-5-21(27)14-19/h2,4-6,8,14,16-18,25-26,29H,3,7,9-13,15H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM60427 (US9067871, 146) Show SMILES O=S(=O)(CC1CC1)NCCOc1ccc2CCC([C@@H](Cc3ccccc3)c2c1)N1CCC1 |r| Show InChI InChI=1S/C26H34N2O3S/c29-32(30,19-21-7-8-21)27-13-16-31-23-11-9-22-10-12-26(28-14-4-15-28)25(24(22)18-23)17-20-5-2-1-3-6-20/h1-3,5-6,9,11,18,21,25-27H,4,7-8,10,12-17,19H2/t25-,26?/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164504 (US9067871, 4) Show SMILES Cn1cc(cn1)S(=O)(=O)NCCOc1ccc2CCC(N)C(Cc3ccc(Cl)c(Cl)c3)c2c1 Show InChI InChI=1S/C23H26Cl2N4O3S/c1-29-14-18(13-27-29)33(30,31)28-8-9-32-17-5-3-16-4-7-23(26)20(19(16)12-17)10-15-2-6-21(24)22(25)11-15/h2-3,5-6,11-14,20,23,28H,4,7-10,26H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164521 (US9067871, 20) Show SMILES Cn1cnc(c1)S(=O)(=O)NCCOc1ccc2CCC(NC=O)C(Cc3ccc(Cl)c(Cl)c3)c2c1 Show InChI InChI=1S/C24H26Cl2N4O4S/c1-30-13-24(27-14-30)35(32,33)29-8-9-34-18-5-3-17-4-7-23(28-15-31)20(19(17)12-18)10-16-2-6-21(25)22(26)11-16/h2-3,5-6,11-15,20,23,29H,4,7-10H2,1H3,(H,28,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164529 (US9067871, 28) Show SMILES Cn1cc(cn1)S(=O)(=O)NCCOc1ccc2CCC(N)C(Cc3ccc(Cl)cc3)c2c1 Show InChI InChI=1S/C23H27ClN4O3S/c1-28-15-20(14-26-28)32(29,30)27-10-11-31-19-8-4-17-5-9-23(25)22(21(17)13-19)12-16-2-6-18(24)7-3-16/h2-4,6-8,13-15,22-23,27H,5,9-12,25H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164562 (US9067871, 48) Show SMILES Cn1cnc(c1)S(=O)(=O)NCCOc1ccc2CCC(N)C(Cc3cccc(Cl)c3)c2c1 Show InChI InChI=1S/C23H27ClN4O3S/c1-28-14-23(26-15-28)32(29,30)27-9-10-31-19-7-5-17-6-8-22(25)21(20(17)13-19)12-16-3-2-4-18(24)11-16/h2-5,7,11,13-15,21-22,27H,6,8-10,12,25H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164569 (US9067871, 55) Show SMILES CCCS(=O)(=O)NCCOc1ccc2CCC(N)C(Cc3cccc(Cl)c3)c2c1 Show InChI InChI=1S/C22H29ClN2O3S/c1-2-12-29(26,27)25-10-11-28-19-8-6-17-7-9-22(24)21(20(17)15-19)14-16-4-3-5-18(23)13-16/h3-6,8,13,15,21-22,25H,2,7,9-12,14,24H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164585 (US9067871, 71) Show SMILES Cn1cc(cn1)S(=O)(=O)NCCOc1ccc2CCC(N)C(Cc3ccc(Cl)cc3Cl)c2c1 Show InChI InChI=1S/C23H26Cl2N4O3S/c1-29-14-19(13-27-29)33(30,31)28-8-9-32-18-6-3-15-4-7-23(26)21(20(15)12-18)10-16-2-5-17(24)11-22(16)25/h2-3,5-6,11-14,21,23,28H,4,7-10,26H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164631 (US9067871, 108) Show SMILES CN(CCOc1ccc2CCC(N)C(Cc3ccc(Cl)c(Cl)c3)c2c1)S(=O)(=O)CC1CC1 Show InChI InChI=1S/C24H30Cl2N2O3S/c1-28(32(29,30)15-16-2-3-16)10-11-31-19-7-5-18-6-9-24(27)21(20(18)14-19)12-17-4-8-22(25)23(26)13-17/h4-5,7-8,13-14,16,21,24H,2-3,6,9-12,15,27H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164639 (US9067871, 116 | US9067871, 117 | US9067871, 118 |...) Show SMILES Cn1cnc(c1)S(=O)(=O)NCCOc1ccc2CCC(C(Cc3ccccc3)c2c1)N1CCCC1 Show InChI InChI=1S/C27H34N4O3S/c1-30-19-27(28-20-30)35(32,33)29-13-16-34-23-11-9-22-10-12-26(31-14-5-6-15-31)25(24(22)18-23)17-21-7-3-2-4-8-21/h2-4,7-9,11,18-20,25-26,29H,5-6,10,12-17H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164643 (US9067871, 121) Show SMILES NC1CCc2ccc(OCCNS(=O)(=O)CC3CC3)cc2C1Cc1ccccc1 Show InChI InChI=1S/C23H30N2O3S/c24-23-11-9-19-8-10-20(28-13-12-25-29(26,27)16-18-6-7-18)15-21(19)22(23)14-17-4-2-1-3-5-17/h1-5,8,10,15,18,22-23,25H,6-7,9,11-14,16,24H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164648 (US9067871, 126) Show SMILES CN(CCOc1ccc2CCC(C(Cc3ccc(Cl)c(Cl)c3)c2c1)N1CCCC1)S(=O)(=O)CC1CC1 Show InChI InChI=1S/C28H36Cl2N2O3S/c1-31(36(33,34)19-20-4-5-20)14-15-35-23-9-7-22-8-11-28(32-12-2-3-13-32)25(24(22)18-23)16-21-6-10-26(29)27(30)17-21/h6-7,9-10,17-18,20,25,28H,2-5,8,11-16,19H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164651 (US9067871, 129) Show SMILES CN(CCOc1ccc2CCC(N)C(Cc3ccc(Cl)cc3)c2c1)S(=O)(=O)CC1CC1 Show InChI InChI=1S/C24H31ClN2O3S/c1-27(31(28,29)16-18-2-3-18)12-13-30-21-10-6-19-7-11-24(26)23(22(19)15-21)14-17-4-8-20(25)9-5-17/h4-6,8-10,15,18,23-24H,2-3,7,11-14,16,26H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164652 (US9067871, 130) Show SMILES CN(CCOc1ccc2CCC(N)C(Cc3ccccc3)c2c1)S(=O)(=O)CC1CC1 Show InChI InChI=1S/C24H32N2O3S/c1-26(30(27,28)17-19-7-8-19)13-14-29-21-11-9-20-10-12-24(25)23(22(20)16-21)15-18-5-3-2-4-6-18/h2-6,9,11,16,19,23-24H,7-8,10,12-15,17,25H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164660 (US9067871, 138) Show SMILES Fc1cccc(CC2C(CCc3ccc(OCCNS(=O)(=O)CC4CC4)cc23)N2CCCC2)c1 Show InChI InChI=1S/C27H35FN2O3S/c28-23-5-3-4-21(16-23)17-26-25-18-24(33-15-12-29-34(31,32)19-20-6-7-20)10-8-22(25)9-11-27(26)30-13-1-2-14-30/h3-5,8,10,16,18,20,26-27,29H,1-2,6-7,9,11-15,17,19H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164661 (US9067871, 139) Show SMILES Fc1cccc(CC2C(CCc3ccc(OCCNS(=O)(=O)CC4CC4)cc23)N2CCC2)c1 Show InChI InChI=1S/C26H33FN2O3S/c27-22-4-1-3-20(15-22)16-25-24-17-23(32-14-11-28-33(30,31)18-19-5-6-19)9-7-21(24)8-10-26(25)29-12-2-13-29/h1,3-4,7,9,15,17,19,25-26,28H,2,5-6,8,10-14,16,18H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164663 (US9067871, 141) Show SMILES Cn1cnc(c1)S(=O)(=O)NCCOc1ccc2CCC(C(Cc3cccc(F)c3)c2c1)N1CCC1 Show InChI InChI=1S/C26H31FN4O3S/c1-30-17-26(28-18-30)35(32,33)29-10-13-34-22-8-6-20-7-9-25(31-11-3-12-31)24(23(20)16-22)15-19-4-2-5-21(27)14-19/h2,4-6,8,14,16-18,24-25,29H,3,7,9-13,15H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164666 (US9067871, 145 | US9067871, 146) Show SMILES Cn1cnc(c1)S(=O)(=O)NCCOc1ccc2CCC(C(Cc3ccccc3)c2c1)N1CCC1 Show InChI InChI=1S/C26H32N4O3S/c1-29-18-26(27-19-29)34(31,32)28-12-15-33-22-10-8-21-9-11-25(30-13-5-14-30)24(23(21)17-22)16-20-6-3-2-4-7-20/h2-4,6-8,10,17-19,24-25,28H,5,9,11-16H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164671 (US9067871, 150) Show SMILES NC1CCc2ccc(OCCNS(=O)(=O)CC3CC3)cc2C1Cc1cc(F)cc(Cl)c1 Show InChI InChI=1S/C23H28ClFN2O3S/c24-18-9-16(10-19(25)12-18)11-22-21-13-20(5-3-17(21)4-6-23(22)26)30-8-7-27-31(28,29)14-15-1-2-15/h3,5,9-10,12-13,15,22-23,27H,1-2,4,6-8,11,14,26H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164673 (US9067871, 152) Show SMILES Cn1cnc(c1)S(=O)(=O)NCCOc1ccc2CCC(C(Cc3ccccc3)c2c1)N1CCC(F)C1 Show InChI InChI=1S/C27H33FN4O3S/c1-31-18-27(29-19-31)36(33,34)30-12-14-35-23-9-7-21-8-10-26(32-13-11-22(28)17-32)25(24(21)16-23)15-20-5-3-2-4-6-20/h2-7,9,16,18-19,22,25-26,30H,8,10-15,17H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164679 (US9067871, 158) Show SMILES CNC1CCc2ccc(OCCNS(=O)(=O)CC3CC3)cc2C1Cc1cc(F)cc(Cl)c1 Show InChI InChI=1S/C24H30ClFN2O3S/c1-27-24-7-5-18-4-6-21(31-9-8-28-32(29,30)15-16-2-3-16)14-22(18)23(24)12-17-10-19(25)13-20(26)11-17/h4,6,10-11,13-14,16,23-24,27-28H,2-3,5,7-9,12,15H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164682 (US9067871, 161) Show SMILES CNC1CCc2ccc(OCCNS(=O)(=O)CC3CC3)cc2C1Cc1ccc(F)cc1 Show InChI InChI=1S/C24H31FN2O3S/c1-26-24-11-7-19-6-10-21(30-13-12-27-31(28,29)16-18-2-3-18)15-22(19)23(24)14-17-4-8-20(25)9-5-17/h4-6,8-10,15,18,23-24,26-27H,2-3,7,11-14,16H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164659 (US9067871, 137 | US9067871, 162) Show SMILES CNC1CCc2ccc(OCCNS(=O)(=O)CC3CC3)cc2C1Cc1ccccc1 Show InChI InChI=1S/C24H32N2O3S/c1-25-24-12-10-20-9-11-21(29-14-13-26-30(27,28)17-19-7-8-19)16-22(20)23(24)15-18-5-3-2-4-6-18/h2-6,9,11,16,19,23-26H,7-8,10,12-15,17H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164685 (US9067871, 164) Show SMILES COc1cccc(CC2C(CCc3ccc(OCCNS(=O)(=O)c4cn(C)cn4)cc23)N2CCCC2)c1 Show InChI InChI=1S/C28H36N4O4S/c1-31-19-28(29-20-31)37(33,34)30-12-15-36-24-10-8-22-9-11-27(32-13-3-4-14-32)26(25(22)18-24)17-21-6-5-7-23(16-21)35-2/h5-8,10,16,18-20,26-27,30H,3-4,9,11-15,17H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164686 (US9067871, 165) Show SMILES Cn1cnc(c1)S(=O)(=O)NCCOc1ccc2CCC(N)C(Cc3cccc(c3)C(F)(F)F)c2c1 Show InChI InChI=1S/C24H27F3N4O3S/c1-31-14-23(29-15-31)35(32,33)30-9-10-34-19-7-5-17-6-8-22(28)21(20(17)13-19)12-16-3-2-4-18(11-16)24(25,26)27/h2-5,7,11,13-15,21-22,30H,6,8-10,12,28H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164693 (US9067871, 172) Show SMILES Cn1cc(cn1)S(=O)(=O)NCc1ccc2CCC(N)C(Cc3ccccc3)c2c1 Show InChI InChI=1S/C22H26N4O2S/c1-26-15-19(14-24-26)29(27,28)25-13-17-7-8-18-9-10-22(23)21(20(18)12-17)11-16-5-3-2-4-6-16/h2-8,12,14-15,21-22,25H,9-11,13,23H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164694 (US9067871, 173) Show SMILES Cn1cnc(c1)S(=O)(=O)NCc1ccc2CCC(N)C(Cc3ccccc3)c2c1 Show InChI InChI=1S/C22H26N4O2S/c1-26-14-22(24-15-26)29(27,28)25-13-17-7-8-18-9-10-21(23)20(19(18)12-17)11-16-5-3-2-4-6-16/h2-8,12,14-15,20-21,25H,9-11,13,23H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164698 (US9067871, 177) Show SMILES Cn1cnc(c1)S(=O)(=O)NCc1ccc2CCC(N)C(Cc3cccc(F)c3)c2c1 Show InChI InChI=1S/C22H25FN4O2S/c1-27-13-22(25-14-27)30(28,29)26-12-16-5-6-17-7-8-21(24)20(19(17)11-16)10-15-3-2-4-18(23)9-15/h2-6,9,11,13-14,20-21,26H,7-8,10,12,24H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164699 (US9067871, 178) Show SMILES Cn1cc(cn1)S(=O)(=O)NCc1ccc2CCC(N)C(Cc3cccc(F)c3)c2c1 Show InChI InChI=1S/C22H25FN4O2S/c1-27-14-19(13-25-27)30(28,29)26-12-16-5-6-17-7-8-22(24)21(20(17)11-16)10-15-3-2-4-18(23)9-15/h2-6,9,11,13-14,21-22,26H,7-8,10,12,24H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164701 (US9067871, 180) Show SMILES Cn1ccc(c1)S(=O)(=O)NCc1ccc2CCC(N)C(Cc3ccccc3)c2c1 Show InChI InChI=1S/C23H27N3O2S/c1-26-12-11-20(16-26)29(27,28)25-15-18-7-8-19-9-10-23(24)22(21(19)14-18)13-17-5-3-2-4-6-17/h2-8,11-12,14,16,22-23,25H,9-10,13,15,24H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164708 (US9067871, 187) Show SMILES CCCS(=O)(=O)NCc1ccc2CCC(NC)C(Cc3ccccc3)c2c1 Show InChI InChI=1S/C22H30N2O2S/c1-3-13-27(25,26)24-16-18-9-10-19-11-12-22(23-2)21(20(19)15-18)14-17-7-5-4-6-8-17/h4-10,15,21-24H,3,11-14,16H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164711 (US9067871, 190) Show SMILES CNC1CCc2ccc(CNS(=O)(=O)c3ccn(C)c3)cc2C1Cc1ccccc1 Show InChI InChI=1S/C24H29N3O2S/c1-25-24-11-10-20-9-8-19(16-26-30(28,29)21-12-13-27(2)17-21)15-22(20)23(24)14-18-6-4-3-5-7-18/h3-9,12-13,15,17,23-26H,10-11,14,16H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164709 (US9067871, 188 | US9067871, 193) Show SMILES CNC1CCc2ccc(CNS(=O)(=O)C3CCC3)cc2C1Cc1ccccc1 Show InChI InChI=1S/C23H30N2O2S/c1-24-23-13-12-19-11-10-18(16-25-28(26,27)20-8-5-9-20)15-21(19)22(23)14-17-6-3-2-4-7-17/h2-4,6-7,10-11,15,20,22-25H,5,8-9,12-14,16H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164727 (US9067871, 203) Show SMILES CCCS(=O)(=O)NCCCc1ccc2CCC(N)C(Cc3ccc(Cl)c(Cl)c3)c2c1 Show InChI InChI=1S/C23H30Cl2N2O2S/c1-2-12-30(28,29)27-11-3-4-16-5-7-18-8-10-23(26)20(19(18)13-16)14-17-6-9-21(24)22(25)15-17/h5-7,9,13,15,20,23,27H,2-4,8,10-12,14,26H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164754 (US9067871, 230) Show SMILES CN(CCCc1ccc2CCC(N)C(Cc3cccc(F)c3)c2c1)S(=O)(=O)CC1CC1 Show InChI InChI=1S/C25H33FN2O2S/c1-28(31(29,30)17-19-7-8-19)13-3-5-18-9-10-21-11-12-25(27)24(23(21)15-18)16-20-4-2-6-22(26)14-20/h2,4,6,9-10,14-15,19,24-25H,3,5,7-8,11-13,16-17,27H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164759 (US9067871, 235) Show SMILES NC1CCc2ccc(OCCNS(=O)(=O)CC3CC3)cc2C1Cc1cccc(F)c1 Show InChI InChI=1S/C23H29FN2O3S/c24-19-3-1-2-17(12-19)13-22-21-14-20(8-6-18(21)7-9-23(22)25)29-11-10-26-30(27,28)15-16-4-5-16/h1-3,6,8,12,14,16,22-23,26H,4-5,7,9-11,13,15,25H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164762 (US9067871, 238) Show SMILES Cn1cnc(c1)S(=O)(=O)NCCOc1ccc2CCC(N)C(Cc3ccccc3)c2c1 Show InChI InChI=1S/C23H28N4O3S/c1-27-15-23(25-16-27)31(28,29)26-11-12-30-19-9-7-18-8-10-22(24)21(20(18)14-19)13-17-5-3-2-4-6-17/h2-7,9,14-16,21-22,26H,8,10-13,24H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164765 (US9067871, 241 | US9067871, 242 | US9067871, 246) Show SMILES CNC1CCc2ccc(OCCNS(=O)(=O)c3ccn(C)c3)cc2C1Cc1cc(F)cc(F)c1 Show InChI InChI=1S/C25H29F2N3O3S/c1-28-25-6-4-18-3-5-21(33-10-8-29-34(31,32)22-7-9-30(2)16-22)15-23(18)24(25)13-17-11-19(26)14-20(27)12-17/h3,5,7,9,11-12,14-16,24-25,28-29H,4,6,8,10,13H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164767 (US9067871, 243 | US9067871, 244 | US9067871, 245) Show SMILES CNC1CCc2ccc(OCCNS(=O)(=O)CC3CC3)cc2C1Cc1cc(F)cc(F)c1 Show InChI InChI=1S/C24H30F2N2O3S/c1-27-24-7-5-18-4-6-21(31-9-8-28-32(29,30)15-16-2-3-16)14-22(18)23(24)12-17-10-19(25)13-20(26)11-17/h4,6,10-11,13-14,16,23-24,27-28H,2-3,5,7-9,12,15H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164763 (US9067871, 239 | US9067871, 240 | US9067871, 247) Show SMILES CNC1CCc2ccc(OCCNS(=O)(=O)CC3CC3)cc2C1Cc1cccc(F)c1 Show InChI InChI=1S/C24H31FN2O3S/c1-26-24-10-8-19-7-9-21(30-12-11-27-31(28,29)16-17-5-6-17)15-22(19)23(24)14-18-3-2-4-20(25)13-18/h2-4,7,9,13,15,17,23-24,26-27H,5-6,8,10-12,14,16H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM164776 (US9067871, 248) Show SMILES CCCS(=O)(=O)NCc1ccc2CCC(C(Cc3ccccc3)c2c1)N1CCC1 Show InChI InChI=1S/C24H32N2O2S/c1-2-15-29(27,28)25-18-20-9-10-21-11-12-24(26-13-6-14-26)23(22(21)17-20)16-19-7-4-3-5-8-19/h3-5,7-10,17,23-25H,2,6,11-16,18H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US9067871 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HV4
					More data for this Ligand-Target Pair

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