Compile Data Set for Download or QSAR

Found 90 hits Enz. Inhib. hit(s) with all data for entry = 7285   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186215 (US9163015, 1) Show SMILES Clc1cccc(Nc2n[nH]c3cccnc23)c1 Show InChI InChI=1S/C12H9ClN4/c13-8-3-1-4-9(7-8)15-12-11-10(16-17-12)5-2-6-14-11/h1-7H,(H2,15,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	138	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186216 (US9163015, 2) Show SMILES Fc1ccc(Nc2n[nH]c3cccnc23)cc1Cl Show InChI InChI=1S/C12H8ClFN4/c13-8-6-7(3-4-9(8)14)16-12-11-10(17-18-12)2-1-5-15-11/h1-6H,(H2,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	33	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186217 (US9163015, 3) Show SMILES FC(F)(F)c1cccc(Nc2n[nH]c3cccnc23)c1 Show InChI InChI=1S/C13H9F3N4/c14-13(15,16)8-3-1-4-9(7-8)18-12-11-10(19-20-12)5-2-6-17-11/h1-7H,(H2,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	145	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186218 (US9163015, 4) Show SMILES Fc1cncc(Nc2n[nH]c3cccnc23)c1 Show InChI InChI=1S/C11H8FN5/c12-7-4-8(6-13-5-7)15-11-10-9(16-17-11)2-1-3-14-10/h1-6H,(H2,15,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	9.18E+3	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186219 (US9163015, 5) Show SMILES Fc1ccc(Nc2n[nH]c3cccnc23)cc1F Show InChI InChI=1S/C12H8F2N4/c13-8-4-3-7(6-9(8)14)16-12-11-10(17-18-12)2-1-5-15-11/h1-6H,(H2,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	644	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186220 (US9163015, 6) Show SMILES COc1cc(Nc2n[nH]c3cccnc23)ccc1Cl Show InChI InChI=1S/C13H11ClN4O/c1-19-11-7-8(4-5-9(11)14)16-13-12-10(17-18-13)3-2-6-15-12/h2-7H,1H3,(H2,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186221 (US9163015, 7) Show SMILES Cc1cc(Nc2n[nH]c3cccnc23)ccc1Cl Show InChI InChI=1S/C13H11ClN4/c1-8-7-9(4-5-10(8)14)16-13-12-11(17-18-13)3-2-6-15-12/h2-7H,1H3,(H2,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	164	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186222 (US9163015, 8) Show SMILES COc1ccc(Nc2n[nH]c3cccnc23)cc1Cl Show InChI InChI=1S/C13H11ClN4O/c1-19-11-5-4-8(7-9(11)14)16-13-12-10(17-18-13)3-2-6-15-12/h2-7H,1H3,(H2,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	282	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186223 (US9163015, 9) Show SMILES FC(F)Oc1cccc(Nc2n[nH]c3cccnc23)c1 Show InChI InChI=1S/C13H10F2N4O/c14-13(15)20-9-4-1-3-8(7-9)17-12-11-10(18-19-12)5-2-6-16-11/h1-7,13H,(H2,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	254	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186224 (US9163015, 10) Show SMILES COc1ccc(Nc2n[nH]c3cccnc23)cc1OC(F)F Show InChI InChI=1S/C14H12F2N4O2/c1-21-10-5-4-8(7-11(10)22-14(15)16)18-13-12-9(19-20-13)3-2-6-17-12/h2-7,14H,1H3,(H2,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	885	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186225 (US9163015, 11) Show SMILES COc1cc(Nc2n[nH]c3cccnc23)ccc1F Show InChI InChI=1S/C13H11FN4O/c1-19-11-7-8(4-5-9(11)14)16-13-12-10(17-18-13)3-2-6-15-12/h2-7H,1H3,(H2,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	1.03E+3	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186226 (US9163015, 12) Show SMILES Fc1cccc(Nc2n[nH]c3cccnc23)c1 Show InChI InChI=1S/C12H9FN4/c13-8-3-1-4-9(7-8)15-12-11-10(16-17-12)5-2-6-14-11/h1-7H,(H2,15,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	584	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186227 (US9163015, 13) Show SMILES Clc1ccnc(Nc2n[nH]c3cccnc23)c1 Show InChI InChI=1S/C11H8ClN5/c12-7-3-5-13-9(6-7)15-11-10-8(16-17-11)2-1-4-14-10/h1-6H,(H2,13,15,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	284	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186228 (US9163015, 14) Show SMILES Clc1cncc(Nc2n[nH]c3cccnc23)c1 Show InChI InChI=1S/C11H8ClN5/c12-7-4-8(6-13-5-7)15-11-10-9(16-17-11)2-1-3-14-10/h1-6H,(H2,15,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	353	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186229 (US9163015, 15) Show SMILES Clc1ccc(Nc2n[nH]c3cccnc23)cn1 Show InChI InChI=1S/C11H8ClN5/c12-9-4-3-7(6-14-9)15-11-10-8(16-17-11)2-1-5-13-10/h1-6H,(H2,15,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186230 (US9163015, 16) Show SMILES Fc1ccc(Cl)cc1Nc1n[nH]c2cccnc12 Show InChI InChI=1S/C12H8ClFN4/c13-7-3-4-8(14)10(6-7)16-12-11-9(17-18-12)2-1-5-15-11/h1-6H,(H2,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	116	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186231 (US9163015, 17) Show SMILES Fc1c(Cl)cccc1Nc1n[nH]c2cccnc12 Show InChI InChI=1S/C12H8ClFN4/c13-7-3-1-4-8(10(7)14)16-12-11-9(17-18-12)5-2-6-15-11/h1-6H,(H2,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	623	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186232 (US9163015, 18) Show SMILES Cc1cccc(Nc2n[nH]c3cccnc23)c1 Show InChI InChI=1S/C13H12N4/c1-9-4-2-5-10(8-9)15-13-12-11(16-17-13)6-3-7-14-12/h2-8H,1H3,(H2,15,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	51.4	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186233 (US9163015, 19) Show SMILES COc1cccc(Nc2n[nH]c3cccnc23)c1 Show InChI InChI=1S/C13H12N4O/c1-18-10-5-2-4-9(8-10)15-13-12-11(16-17-13)6-3-7-14-12/h2-8H,1H3,(H2,15,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	169	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186234 (US9163015, 20) Show SMILES N(c1n[nH]c2cccnc12)c1ccccc1 Show InChI InChI=1S/C12H10N4/c1-2-5-9(6-3-1)14-12-11-10(15-16-12)7-4-8-13-11/h1-8H,(H2,14,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	1.44E+3	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186235 (US9163015, 21) Show SMILES Clc1cc(Nc2n[nH]c3cccnc23)ccc1C#N Show InChI InChI=1S/C13H8ClN5/c14-10-6-9(4-3-8(10)7-15)17-13-12-11(18-19-13)2-1-5-16-12/h1-6H,(H2,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	93	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186236 (US9163015, 22) Show SMILES FC(F)(F)c1ccc(Nc2n[nH]c3cccnc23)cc1Cl Show InChI InChI=1S/C13H8ClF3N4/c14-9-6-7(3-4-8(9)13(15,16)17)19-12-11-10(20-21-12)2-1-5-18-11/h1-6H,(H2,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	2.15E+3	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186237 (US9163015, 23) Show SMILES Clc1cc(Nc2n[nH]c3cccnc23)ccn1 Show InChI InChI=1S/C11H8ClN5/c12-9-6-7(3-5-13-9)15-11-10-8(16-17-11)2-1-4-14-10/h1-6H,(H2,13,15,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	1.49E+3	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186238 (US9163015, 24) Show SMILES Clc1cc(Nc2n[nH]c3cccnc23)ccc1Oc1ncccn1 Show InChI InChI=1S/C16H11ClN6O/c17-11-9-10(4-5-13(11)24-16-19-7-2-8-20-16)21-15-14-12(22-23-15)3-1-6-18-14/h1-9H,(H2,21,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	116	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186239 (US9163015, 25) Show SMILES Clc1cccc(Nc2c[nH]c3cccnc23)c1 Show InChI InChI=1S/C13H10ClN3/c14-9-3-1-4-10(7-9)17-12-8-16-11-5-2-6-15-13(11)12/h1-8,16-17H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.36E+3	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186240 (US9163015, 26) Show SMILES Fc1ccc(Nc2n[nH]c3cncnc23)cc1Cl Show InChI InChI=1S/C11H7ClFN5/c12-7-3-6(1-2-8(7)13)16-11-10-9(17-18-11)4-14-5-15-10/h1-5H,(H2,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	3.07E+3	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186241 (US9163015, 27) Show SMILES Clc1cc(ccc1Oc1ncccn1)N(c1n[nH]c2cccnc12)c1ncccn1 Show InChI InChI=1S/C20H13ClN8O/c21-14-12-13(5-6-16(14)30-20-25-10-3-11-26-20)29(19-23-8-2-9-24-19)18-17-15(27-28-18)4-1-7-22-17/h1-12H,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	9.07E+3	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186242 (US9163015, 28) Show SMILES Fc1ccc(Nc2n[nH]c3nccnc23)cc1Cl Show InChI InChI=1S/C11H7ClFN5/c12-7-5-6(1-2-8(7)13)16-11-9-10(17-18-11)15-4-3-14-9/h1-5H,(H2,15,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	156	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186243 (US9163015, 29) Show SMILES CC(C)C1CCC(CC1)Nc1n[nH]c2cccnc12 |(-8.44,-4.69,;-7.97,-3.22,;-9,-2.08,;-6.46,-2.9,;-5.43,-4.05,;-3.92,-3.73,;-3.45,-2.26,;-4.48,-1.12,;-5.98,-1.44,;-1.94,-1.94,;-1.46,-.48,;-2.37,.77,;-1.46,2.02,;,1.54,;1.33,2.31,;2.67,1.54,;2.67,,;1.33,-.77,;)| Show InChI InChI=1S/C15H22N4/c1-10(2)11-5-7-12(8-6-11)17-15-14-13(18-19-15)4-3-9-16-14/h3-4,9-12H,5-8H2,1-2H3,(H2,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	5.22E+3	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186244 (US9163015, 30) Show SMILES Clc1cc(Nc2n[nH]c3cccnc23)cnc1N1CCOCC1 Show InChI InChI=1S/C15H15ClN6O/c16-11-8-10(9-18-15(11)22-4-6-23-7-5-22)19-14-13-12(20-21-14)2-1-3-17-13/h1-3,8-9H,4-7H2,(H2,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	2.38E+3	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186245 (US9163015, 31) Show SMILES Clc1cc(Nc2n[nH]c3cccnc23)cnc1N1CCCC1 Show InChI InChI=1S/C15H15ClN6/c16-11-8-10(9-18-15(11)22-6-1-2-7-22)19-14-13-12(20-21-14)4-3-5-17-13/h3-5,8-9H,1-2,6-7H2,(H2,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186246 (US9163015, 32) Show SMILES Clc1cncc(Nc2n[nH]c3cccnc23)n1 Show InChI InChI=1S/C10H7ClN6/c11-7-4-12-5-8(14-7)15-10-9-6(16-17-10)2-1-3-13-9/h1-5H,(H2,14,15,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	9.99E+3	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186247 (US9163015, 33) Show SMILES Cc1cncc(Nc2n[nH]c3cccnc23)c1 Show InChI InChI=1S/C12H11N5/c1-8-5-9(7-13-6-8)15-12-11-10(16-17-12)3-2-4-14-11/h2-7H,1H3,(H2,15,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	7.38E+3	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186248 (US9163015, 34) Show SMILES Fc1ncc(Cl)cc1Nc1n[nH]c2cccnc12 Show InChI InChI=1S/C11H7ClFN5/c12-6-4-8(10(13)15-5-6)16-11-9-7(17-18-11)2-1-3-14-9/h1-5H,(H2,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	597	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186249 (US9163015, 35) Show SMILES CN1C(C(=O)N(C1=O)c1ccc(Nc2n[nH]c3cccnc23)cc1Cl)C(C)(C)C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	753	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186250 (US9163015, 36) Show SMILES Oc1ccc(Nc2n[nH]c3cccnc23)cc1Cl Show InChI InChI=1S/C12H9ClN4O/c13-8-6-7(3-4-10(8)18)15-12-11-9(16-17-12)2-1-5-14-11/h1-6,18H,(H2,15,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	217	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186251 (US9163015, 37) Show SMILES Cc1cc(C)cc(Nc2n[nH]c3cccnc23)c1 Show InChI InChI=1S/C14H14N4/c1-9-6-10(2)8-11(7-9)16-14-13-12(17-18-14)4-3-5-15-13/h3-8H,1-2H3,(H2,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	177	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186252 (US9163015, 38) Show SMILES FC(F)(F)c1cccc(c1)C(=O)c1ccc(Nc2n[nH]c3cccnc23)cc1Cl Show InChI InChI=1S/C20H12ClF3N4O/c21-15-10-13(26-19-17-16(27-28-19)5-2-8-25-17)6-7-14(15)18(29)11-3-1-4-12(9-11)20(22,23)24/h1-10H,(H2,26,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	3.88E+3	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186253 (US9163015, 39) Show SMILES N(c1n[nH]c2cccnc12)c1cncnc1 Show InChI InChI=1S/C10H8N6/c1-2-8-9(13-3-1)10(16-15-8)14-7-4-11-6-12-5-7/h1-6H,(H2,14,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	8.99E+3	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186254 (US10227343, Example 83 | US9163015, 40) Show SMILES N(c1n[nH]c2cccnc12)c1cnc2ccccc2c1 Show InChI InChI=1S/C15H11N5/c1-2-5-12-10(4-1)8-11(9-17-12)18-15-14-13(19-20-15)6-3-7-16-14/h1-9H,(H2,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	961	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186255 (US9163015, 41) Show SMILES Fc1ccc(Nc2n[nH]c3scnc23)cc1Cl Show InChI InChI=1S/C10H6ClFN4S/c11-6-3-5(1-2-7(6)12)14-9-8-10(16-15-9)17-4-13-8/h1-4H,(H2,14,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186256 (US9163015, 42) Show SMILES Clc1cc(Nc2n[nH]c3cccnc23)cc(Cl)c1Cl Show InChI InChI=1S/C12H7Cl3N4/c13-7-4-6(5-8(14)10(7)15)17-12-11-9(18-19-12)2-1-3-16-11/h1-5H,(H2,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	721	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186257 (US9163015, 43) Show SMILES Fc1c(Cl)cc(Nc2n[nH]c3cccnc23)cc1Cl Show InChI InChI=1S/C12H7Cl2FN4/c13-7-4-6(5-8(14)10(7)15)17-12-11-9(18-19-12)2-1-3-16-11/h1-5H,(H2,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	410	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186258 (US9163015, 44) Show SMILES Cc1ccc(NC(=O)Nc2n[nH]c3cccnc23)cc1C Show InChI InChI=1S/C15H15N5O/c1-9-5-6-11(8-10(9)2)17-15(21)18-14-13-12(19-20-14)4-3-7-16-13/h3-8H,1-2H3,(H3,17,18,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	1.28E+4	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186259 (US9163015, 45) Show SMILES N(c1nccs1)c1n[nH]c2cccnc12 Show InChI InChI=1S/C9H7N5S/c1-2-6-7(10-3-1)8(14-13-6)12-9-11-4-5-15-9/h1-5H,(H2,11,12,13,14)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186260 (US9163015, 46) Show SMILES Cc1cc(NC(=O)Nc2n[nH]c3cccnc23)ccc1F Show InChI InChI=1S/C14H12FN5O/c1-8-7-9(4-5-10(8)15)17-14(21)18-13-12-11(19-20-13)3-2-6-16-12/h2-7H,1H3,(H3,17,18,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	6.84E+3	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186261 (US9163015, 47) Show SMILES Clc1cc(Nc2n[nH]c3cccnc23)cnc1Cl Show InChI InChI=1S/C11H7Cl2N5/c12-7-4-6(5-15-10(7)13)16-11-9-8(17-18-11)2-1-3-14-9/h1-5H,(H2,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186262 (US9163015, 48) Show SMILES CNc1ncc(Nc2n[nH]c3cccnc23)cc1Cl Show InChI InChI=1S/C12H11ClN6/c1-14-11-8(13)5-7(6-16-11)17-12-10-9(18-19-12)3-2-4-15-10/h2-6H,1H3,(H,14,16)(H2,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	6.44E+3	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186263 (US9163015, 49) Show SMILES C(Nc1n[nH]c2cccnc12)C1CCCCC1 Show InChI InChI=1S/C13H18N4/c1-2-5-10(6-3-1)9-15-13-12-11(16-17-13)7-4-8-14-12/h4,7-8,10H,1-3,5-6,9H2,(H2,15,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186264 (US9163015, 50) Show SMILES Clc1cccc(CNc2n[nH]c3cccnc23)c1 Show InChI InChI=1S/C13H11ClN4/c14-10-4-1-3-9(7-10)8-16-13-12-11(17-18-13)5-2-6-15-12/h1-7H,8H2,(H2,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	1.73E+4	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair

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