Compile Data Set for Download or QSAR

Found 683 hits Enz. Inhib. hit(s) with all data for entry = 8470   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM250758 (US9452986, 62) Show SMILES C[C@@H]1CN(CCN1)C(=O)c1ccc2cc(Oc3ccc(nc3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C21H19F3N4O2/c1-13-12-28(9-8-25-13)20(29)18-5-2-14-10-15(3-6-17(14)27-18)30-16-4-7-19(26-11-16)21(22,23)24/h2-7,10-11,13,25H,8-9,12H2,1H3/t13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.8 (Essen, Ann Arbor, Mich.) were quickly thawed and pl...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM251142 (US9452986, 446) Show SMILES CCN(CC)C(=O)CNC(=O)c1ccc2cc(Oc3ccc(cn3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C22H21F3N4O3/c1-3-29(4-2)20(30)13-27-21(31)18-8-5-14-11-16(7-9-17(14)28-18)32-19-10-6-15(12-26-19)22(23,24)25/h5-12H,3-4,13H2,1-2H3,(H,27,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	166	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM250871 (US9452986, 175) Show SMILES FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)NCCN2CCCCC2)nc1 Show InChI InChI=1S/C23H23F3N4O2/c24-23(25,26)17-5-9-21(28-15-17)32-18-6-8-19-16(14-18)4-7-20(29-19)22(31)27-10-13-30-11-2-1-3-12-30/h4-9,14-15H,1-3,10-13H2,(H,27,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	206	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM251208 (US9452986, 512) Show SMILES FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)N[C@H]2CCNC(=O)C2)nc1 Show InChI InChI=1S/C21H17F3N4O3/c22-21(23,24)13-2-6-19(26-11-13)31-15-3-5-16-12(9-15)1-4-17(28-16)20(30)27-14-7-8-25-18(29)10-14/h1-6,9,11,14H,7-8,10H2,(H,25,29)(H,27,30)/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	213	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.8 (Essen, Ann Arbor, Mich.) were quickly thawed and pl...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM251010 (US9452986, 314) Show SMILES FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)N2CCC(C2)N2CCC2)nc1 Show InChI InChI=1S/C23H21F3N4O2/c24-23(25,26)16-3-7-21(27-13-16)32-18-4-6-19-15(12-18)2-5-20(28-19)22(31)30-11-8-17(14-30)29-9-1-10-29/h2-7,12-13,17H,1,8-11,14H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	218	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM250796 (US9452986, 100) Show SMILES O=C(NCCCN1CCCCC1)c1ccc2cc(Oc3ccc(cc3)C#N)ccc2n1 Show InChI InChI=1S/C25H26N4O2/c26-18-19-5-8-21(9-6-19)31-22-10-12-23-20(17-22)7-11-24(28-23)25(30)27-13-4-16-29-14-2-1-3-15-29/h5-12,17H,1-4,13-16H2,(H,27,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	221	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM250778 (US9452986, 82) Show SMILES O=C(NCCN1CCCCC1)c1ccc2cc(Oc3ccc(cc3)C#N)ccc2n1 Show InChI InChI=1S/C24H24N4O2/c25-17-18-4-7-20(8-5-18)30-21-9-11-22-19(16-21)6-10-23(27-22)24(29)26-12-15-28-13-2-1-3-14-28/h4-11,16H,1-3,12-15H2,(H,26,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	222	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM250704 (US9452986, 8) Show SMILES NC1CN(C1)C(=O)c1ccc2cc(Oc3ccc(cn3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C19H15F3N4O2/c20-19(21,22)12-2-6-17(24-8-12)28-14-3-5-15-11(7-14)1-4-16(25-15)18(27)26-9-13(23)10-26/h1-8,13H,9-10,23H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	232	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM251289 (US9452986, 593) Show SMILES COC[C@@H]1CN(CCN1)C(=O)c1ccc2cc(Oc3ccc(cn3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C22H21F3N4O3/c1-31-13-16-12-29(9-8-26-16)21(30)19-5-2-14-10-17(4-6-18(14)28-19)32-20-7-3-15(11-27-20)22(23,24)25/h2-7,10-11,16,26H,8-9,12-13H2,1H3/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	238	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM250781 (US9452986, 85) Show SMILES CN(C)CCCNC(=O)c1ccc2cc(Oc3ccc(cc3)C#N)ccc2n1 Show InChI InChI=1S/C22H22N4O2/c1-26(2)13-3-12-24-22(27)21-10-6-17-14-19(9-11-20(17)25-21)28-18-7-4-16(15-23)5-8-18/h4-11,14H,3,12-13H2,1-2H3,(H,24,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	238	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM250926 (US9452986, 230) Show SMILES FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)N[C@@H]2CC[C@H]3CN(Cc4ccccc4)C[C@@H]23)nc1 Show InChI InChI=1S/C30H27F3N4O2/c31-30(32,33)22-8-13-28(34-15-22)39-23-9-12-25-20(14-23)6-11-27(35-25)29(38)36-26-10-7-21-17-37(18-24(21)26)16-19-4-2-1-3-5-19/h1-6,8-9,11-15,21,24,26H,7,10,16-18H2,(H,36,38)/t21-,24+,26+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	259	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM250701 (US9452986, 5) Show SMILES FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)N[C@@H]2CCS(=O)(=O)C2)nc1 Show InChI InChI=1S/C20H16F3N3O4S/c21-20(22,23)13-2-6-18(24-10-13)30-15-3-5-16-12(9-15)1-4-17(26-16)19(27)25-14-7-8-31(28,29)11-14/h1-6,9-10,14H,7-8,11H2,(H,25,27)/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	262	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM251141 (US9452986, 445) Show SMILES FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)NCCC(=O)N2CCCC2)nc1 Show InChI InChI=1S/C23H21F3N4O3/c24-23(25,26)16-4-8-20(28-14-16)33-17-5-7-18-15(13-17)3-6-19(29-18)22(32)27-10-9-21(31)30-11-1-2-12-30/h3-8,13-14H,1-2,9-12H2,(H,27,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	268	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM250736 (US9452986, 40) Show SMILES FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)NC2CCNC(=O)C2)nc1 Show InChI InChI=1S/C21H17F3N4O3/c22-21(23,24)13-2-6-19(26-11-13)31-15-3-5-16-12(9-15)1-4-17(28-16)20(30)27-14-7-8-25-18(29)10-14/h1-6,9,11,14H,7-8,10H2,(H,25,29)(H,27,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	285	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM251015 (US9452986, 319) Show SMILES FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)N2CC[C@H](C2)N2CCCCC2)nc1 Show InChI InChI=1S/C25H25F3N4O2/c26-25(27,28)18-5-9-23(29-15-18)34-20-6-8-21-17(14-20)4-7-22(30-21)24(33)32-13-10-19(16-32)31-11-2-1-3-12-31/h4-9,14-15,19H,1-3,10-13,16H2/t19-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	285	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM251196 (US9452986, 500) Show SMILES Cc1ccccc1NC(=O)CCNC(=O)c1ccc2cc(Oc3ccc(cn3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C26H21F3N4O3/c1-16-4-2-3-5-20(16)33-23(34)12-13-30-25(35)22-9-6-17-14-19(8-10-21(17)32-22)36-24-11-7-18(15-31-24)26(27,28)29/h2-11,14-15H,12-13H2,1H3,(H,30,35)(H,33,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	293	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM250870 (US9452986, 174) Show SMILES FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)NCCN2CCCC2)nc1 Show InChI InChI=1S/C22H21F3N4O2/c23-22(24,25)16-4-8-20(27-14-16)31-17-5-7-18-15(13-17)3-6-19(28-18)21(30)26-9-12-29-10-1-2-11-29/h3-8,13-14H,1-2,9-12H2,(H,26,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	294	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM251270 (US9452986, 574) Show SMILES FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)NC2CC(C2)N2CCOCC2)cn1 |(-9.34,-3.85,;-8,-3.08,;-7.23,-4.41,;-8.77,-1.75,;-6.67,-2.31,;-5.33,-3.08,;-4,-2.31,;-4,-.77,;-2.67,,;-1.33,-.77,;-1.33,-2.31,;,-3.08,;1.33,-2.31,;2.67,-3.08,;4,-2.31,;4,-.77,;2.67,,;1.33,-.77,;;5.33,-3.08,;5.33,-4.62,;6.67,-2.31,;8,-3.08,;9.49,-2.68,;9.89,-4.17,;8.4,-4.57,;11.22,-4.94,;12.56,-4.17,;13.89,-4.94,;13.89,-6.48,;12.56,-7.25,;11.22,-6.48,;-5.33,,;-6.67,-.77,)| Show InChI InChI=1S/C24H23F3N4O3/c25-24(26,27)22-6-3-19(14-28-22)34-18-2-5-20-15(11-18)1-4-21(30-20)23(32)29-16-12-17(13-16)31-7-9-33-10-8-31/h1-6,11,14,16-17H,7-10,12-13H2,(H,29,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	295	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM251280 (US9452986, 584) Show SMILES F[C@@H]1CNCC[C@H]1NC(=O)c1ccc2cc(Oc3ccc(cn3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C21H18F4N4O2/c22-15-11-26-8-7-17(15)29-20(30)18-4-1-12-9-14(3-5-16(12)28-18)31-19-6-2-13(10-27-19)21(23,24)25/h1-6,9-10,15,17,26H,7-8,11H2,(H,29,30)/t15-,17-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	304	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM250970 (US9452986, 274) Show SMILES CC(C)[C@H]1CN(CCN1)C(=O)c1ccc2cc(Oc3ccc(cn3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C23H23F3N4O2/c1-14(2)20-13-30(10-9-27-20)22(31)19-6-3-15-11-17(5-7-18(15)29-19)32-21-8-4-16(12-28-21)23(24,25)26/h3-8,11-12,14,20,27H,9-10,13H2,1-2H3/t20-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	304	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM250734 (US9452986, 38) Show SMILES C[C@@H](O)CNC(=O)c1ccc2cc(Oc3ccc(cn3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C19H16F3N3O3/c1-11(26)9-24-18(27)16-5-2-12-8-14(4-6-15(12)25-16)28-17-7-3-13(10-23-17)19(20,21)22/h2-8,10-11,26H,9H2,1H3,(H,24,27)/t11-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	311	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM250741 (US9452986, 45) Show SMILES CCN1CC(CC1=O)NC(=O)c1ccc2cc(Oc3ccc(cn3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C22H19F3N4O3/c1-2-29-12-15(10-20(29)30)27-21(31)18-6-3-13-9-16(5-7-17(13)28-18)32-19-8-4-14(11-26-19)22(23,24)25/h3-9,11,15H,2,10,12H2,1H3,(H,27,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	325	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM250792 (US9452986, 96) Show SMILES O=C(NCCN1CCCC1)c1ccc2cc(Oc3ccc(cc3)C#N)ccc2n1 Show InChI InChI=1S/C23H22N4O2/c24-16-17-3-6-19(7-4-17)29-20-8-10-21-18(15-20)5-9-22(26-21)23(28)25-11-14-27-12-1-2-13-27/h3-10,15H,1-2,11-14H2,(H,25,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	329	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM250743 (US9452986, 47) Show SMILES FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)N2CCN(CC2)C2CCC2)nc1 Show InChI InChI=1S/C24H23F3N4O2/c25-24(26,27)17-5-9-22(28-15-17)33-19-6-8-20-16(14-19)4-7-21(29-20)23(32)31-12-10-30(11-13-31)18-2-1-3-18/h4-9,14-15,18H,1-3,10-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	334	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.8 (Essen, Ann Arbor, Mich.) were quickly thawed and pl...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM250742 (US9452986, 46) Show SMILES CCN1CC(CC1=O)NC(=O)c1ccc2cc(Oc3ccc(cn3)C(F)F)ccc2n1 Show InChI InChI=1S/C22H20F2N4O3/c1-2-28-12-15(10-20(28)29)26-22(30)18-6-3-13-9-16(5-7-17(13)27-18)31-19-8-4-14(11-25-19)21(23)24/h3-9,11,15,21H,2,10,12H2,1H3,(H,26,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	344	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM250708 (US9452986, 12) Show SMILES C[C@@H]1CN(CCN1)C(=O)c1ccc2cc(Oc3ccc(cn3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C21H19F3N4O2/c1-13-12-28(9-8-25-13)20(29)18-5-2-14-10-16(4-6-17(14)27-18)30-19-7-3-15(11-26-19)21(22,23)24/h2-7,10-11,13,25H,8-9,12H2,1H3/t13-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	348	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM251157 (US9452986, 461) Show SMILES CCN(CC)C(=O)CNC(=O)c1ccc2cc(Oc3ccc(cn3)C(F)F)ccc2n1 Show InChI InChI=1S/C22H22F2N4O3/c1-3-28(4-2)20(29)13-26-22(30)18-8-5-14-11-16(7-9-17(14)27-18)31-19-10-6-15(12-25-19)21(23)24/h5-12,21H,3-4,13H2,1-2H3,(H,26,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	354	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM251219 (US9452986, 523) Show SMILES CCN1CC(CC1=O)NC(=O)c1ccc2cc(Oc3ccc(nc3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C22H19F3N4O3/c1-2-29-12-14(10-20(29)30)27-21(31)18-6-3-13-9-15(4-7-17(13)28-18)32-16-5-8-19(26-11-16)22(23,24)25/h3-9,11,14H,2,10,12H2,1H3,(H,27,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	356	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM251061 (US9452986, 365) Show SMILES FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)NCCN2CCSCC2)nc1 Show InChI InChI=1S/C22H21F3N4O2S/c23-22(24,25)16-2-6-20(27-14-16)31-17-3-5-18-15(13-17)1-4-19(28-18)21(30)26-7-8-29-9-11-32-12-10-29/h1-6,13-14H,7-12H2,(H,26,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	356	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM250786 (US9452986, 90) Show SMILES O=C(N[C@H]1CCOC1=O)c1ccc2cc(Oc3ccc(cc3)C#N)ccc2n1 Show InChI InChI=1S/C21H15N3O4/c22-12-13-1-4-15(5-2-13)28-16-6-8-17-14(11-16)3-7-18(23-17)20(25)24-19-9-10-27-21(19)26/h1-8,11,19H,9-10H2,(H,24,25)/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	368	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM251213 (US9452986, 517) Show SMILES CCN(CC)C(=O)CNC(=O)c1ccc2cc(Oc3ccc(nc3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C22H21F3N4O3/c1-3-29(4-2)20(30)13-27-21(31)18-8-5-14-11-15(6-9-17(14)28-18)32-16-7-10-19(26-12-16)22(23,24)25/h5-12H,3-4,13H2,1-2H3,(H,27,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM251060 (US9452986, 364) Show SMILES CC1(C)CN(CCNC(=O)c2ccc3cc(Oc4ccc(cn4)C(F)(F)F)ccc3n2)C1 Show InChI InChI=1S/C23H23F3N4O2/c1-22(2)13-30(14-22)10-9-27-21(31)19-6-3-15-11-17(5-7-18(15)29-19)32-20-8-4-16(12-28-20)23(24,25)26/h3-8,11-12H,9-10,13-14H2,1-2H3,(H,27,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM251144 (US9452986, 448) Show SMILES CN1CC(CC1=O)NC(=O)c1ccc2cc(Oc3ccc(cn3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C21H17F3N4O3/c1-28-11-14(9-19(28)29)26-20(30)17-5-2-12-8-15(4-6-16(12)27-17)31-18-7-3-13(10-25-18)21(22,23)24/h2-8,10,14H,9,11H2,1H3,(H,26,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	371	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM251095 (US9452986, 399) Show SMILES FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)NC2COC2)nc1 Show InChI InChI=1S/C19H14F3N3O3/c20-19(21,22)12-2-6-17(23-8-12)28-14-3-5-15-11(7-14)1-4-16(25-15)18(26)24-13-9-27-10-13/h1-8,13H,9-10H2,(H,24,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	375	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM251127 (US9452986, 431) Show SMILES FC(F)(F)Oc1ccc(Oc2ccc3nc(ccc3c2)C(=O)N2CCNCC2)nc1 Show InChI InChI=1S/C20H17F3N4O3/c21-20(22,23)30-15-3-6-18(25-12-15)29-14-2-5-16-13(11-14)1-4-17(26-16)19(28)27-9-7-24-8-10-27/h1-6,11-12,24H,7-10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	382	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.8 (Essen, Ann Arbor, Mich.) were quickly thawed and pl...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM250760 (US9452986, 64) Show SMILES COC[C@@H]1CN(CCN1)C(=O)c1ccc2cc(Oc3ccc(nc3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C22H21F3N4O3/c1-31-13-15-12-29(9-8-26-15)21(30)19-5-2-14-10-16(3-6-18(14)28-19)32-17-4-7-20(27-11-17)22(23,24)25/h2-7,10-11,15,26H,8-9,12-13H2,1H3/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	382	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM250733 (US9452986, 37) Show SMILES FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)NCC2CCO2)nc1 Show InChI InChI=1S/C20H16F3N3O3/c21-20(22,23)13-2-6-18(24-10-13)29-14-3-5-16-12(9-14)1-4-17(26-16)19(27)25-11-15-7-8-28-15/h1-6,9-10,15H,7-8,11H2,(H,25,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	392	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM251239 (US9452986, 543) Show SMILES CC[C@@H]1CN(CCN1)C(=O)c1ccc2cc(Oc3ccc(nc3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C22H21F3N4O2/c1-2-15-13-29(10-9-26-15)21(30)19-6-3-14-11-16(4-7-18(14)28-19)31-17-5-8-20(27-12-17)22(23,24)25/h3-8,11-12,15,26H,2,9-10,13H2,1H3/t15-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM251089 (US9452986, 393) Show SMILES FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)N[C@@H]2CCOC2)nc1 Show InChI InChI=1S/C20H16F3N3O3/c21-20(22,23)13-2-6-18(24-10-13)29-15-3-5-16-12(9-15)1-4-17(26-16)19(27)25-14-7-8-28-11-14/h1-6,9-10,14H,7-8,11H2,(H,25,27)/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	399	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM251097 (US9452986, 401) Show SMILES O[C@@H]1CCC[C@@H]1NC(=O)c1ccc2cc(Oc3ccc(cn3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C21H18F3N3O3/c22-21(23,24)13-5-9-19(25-11-13)30-14-6-8-15-12(10-14)4-7-17(26-15)20(29)27-16-2-1-3-18(16)28/h4-11,16,18,28H,1-3H2,(H,27,29)/t16-,18+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM250959 (US9452986, 263) Show SMILES CC(C)[C@@H]1CN(CCN1)C(=O)c1ccc2cc(Oc3ccc(cn3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C23H23F3N4O2/c1-14(2)20-13-30(10-9-27-20)22(31)19-6-3-15-11-17(5-7-18(15)29-19)32-21-8-4-16(12-28-21)23(24,25)26/h3-8,11-12,14,20,27H,9-10,13H2,1-2H3/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	402	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM251090 (US9452986, 394 | US9452986, 409) Show SMILES FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)NC[C@H]2CCCO2)nc1 Show InChI InChI=1S/C21H18F3N3O3/c22-21(23,24)14-4-8-19(25-11-14)30-15-5-7-17-13(10-15)3-6-18(27-17)20(28)26-12-16-2-1-9-29-16/h3-8,10-11,16H,1-2,9,12H2,(H,26,28)/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	403	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM251149 (US9452986, 453) Show SMILES CCN(CC)C(=O)CCNC(=O)c1ccc2cc(Oc3ccc(cn3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C23H23F3N4O3/c1-3-30(4-2)21(31)11-12-27-22(32)19-8-5-15-13-17(7-9-18(15)29-19)33-20-10-6-16(14-28-20)23(24,25)26/h5-10,13-14H,3-4,11-12H2,1-2H3,(H,27,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	405	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM250712 (US9452986, 16) Show SMILES CC[C@@H]1CN(CCN1)C(=O)c1ccc2cc(Oc3ccc(cn3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C22H21F3N4O2/c1-2-16-13-29(10-9-26-16)21(30)19-6-3-14-11-17(5-7-18(14)28-19)31-20-8-4-15(12-27-20)22(23,24)25/h3-8,11-12,16,26H,2,9-10,13H2,1H3/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	406	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM250750 (US9452986, 54) Show SMILES Fc1ccc(cc1)N1CC(CC1=O)NC(=O)c1ccc2cc(Oc3ccc(cn3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C26H18F4N4O3/c27-17-3-5-19(6-4-17)34-14-18(12-24(34)35)32-25(36)22-8-1-15-11-20(7-9-21(15)33-22)37-23-10-2-16(13-31-23)26(28,29)30/h1-11,13,18H,12,14H2,(H,32,36)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	409	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM251198 (US9452986, 502) Show SMILES COc1ccccc1N1CC(CC1=O)NC(=O)c1ccc2cc(Oc3ccc(cn3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C27H21F3N4O4/c1-37-23-5-3-2-4-22(23)34-15-18(13-25(34)35)32-26(36)21-9-6-16-12-19(8-10-20(16)33-21)38-24-11-7-17(14-31-24)27(28,29)30/h2-12,14,18H,13,15H2,1H3,(H,32,36)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	429	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM251032 (US9452986, 336) Show SMILES OC1(CNC(=O)c2ccc3cc(Oc4ccc(cn4)C(F)(F)F)ccc3n2)CCC1 Show InChI InChI=1S/C21H18F3N3O3/c22-21(23,24)14-3-7-18(25-11-14)30-15-4-6-16-13(10-15)2-5-17(27-16)19(28)26-12-20(29)8-1-9-20/h2-7,10-11,29H,1,8-9,12H2,(H,26,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	439	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM251129 (US9452986, 433) Show SMILES FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)NC2CC(C2)N2CCOCC2)nc1 |(-9.34,-3.85,;-8,-3.08,;-7.23,-4.41,;-8.77,-1.75,;-6.67,-2.31,;-5.33,-3.08,;-4,-2.31,;-4,-.77,;-2.67,,;-1.33,-.77,;-1.33,-2.31,;,-3.08,;1.33,-2.31,;2.67,-3.08,;4,-2.31,;4,-.77,;2.67,,;1.33,-.77,;;5.33,-3.08,;5.33,-4.62,;6.67,-2.31,;8,-3.08,;9.49,-2.68,;9.89,-4.17,;8.4,-4.57,;11.22,-4.94,;12.56,-4.17,;13.89,-4.94,;13.89,-6.48,;12.56,-7.25,;11.22,-6.48,;-5.33,,;-6.67,-.77,)| Show InChI InChI=1S/C24H23F3N4O3/c25-24(26,27)16-2-6-22(28-14-16)34-19-3-5-20-15(11-19)1-4-21(30-20)23(32)29-17-12-18(13-17)31-7-9-33-10-8-31/h1-6,11,14,17-18H,7-10,12-13H2,(H,29,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	442	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM251090 (US9452986, 394 | US9452986, 409) Show SMILES FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)NC[C@H]2CCCO2)nc1 Show InChI InChI=1S/C21H18F3N3O3/c22-21(23,24)14-4-8-19(25-11-14)30-15-5-7-17-13(10-15)3-6-18(27-17)20(28)26-12-16-2-1-9-29-16/h3-8,10-11,16H,1-2,9,12H2,(H,26,28)/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	443	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM251267 (US9452986, 571) Show SMILES FC(F)(F)c1ccc(Oc2ccc3nc(ccc3c2)C(=O)NCC(=O)N2CCC2)nc1 Show InChI InChI=1S/C21H17F3N4O3/c22-21(23,24)14-3-7-18(25-11-14)31-15-4-6-16-13(10-15)2-5-17(27-16)20(30)26-12-19(29)28-8-1-9-28/h2-7,10-11H,1,8-9,12H2,(H,26,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	448	n/a	n/a	n/a	n/a	n/a	37
AbbVie Inc. US Patent					Assay Description Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...				US Patent US9452986 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RQS
					More data for this Ligand-Target Pair

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