Compile Data Set for Download or QSAR

Found 90 hits Enz. Inhib. hit(s) with all data for entry = 8882   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM120095 (US10525036, Example GDC-0994 | US10934304, Example...) Show SMILES Cn1nccc1Nc1nccc(n1)-c1ccn([C@H](CO)c2ccc(Cl)c(F)c2)c(=O)c1 |r| Show InChI InChI=1S/C21H18ClFN6O2/c1-28-19(5-8-25-28)27-21-24-7-4-17(26-21)13-6-9-29(20(31)11-13)18(12-30)14-2-3-15(22)16(23)10-14/h2-11,18,30H,12H2,1H3,(H,24,26,27)/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	PDB US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM120095 (US10525036, Example GDC-0994 | US10934304, Example...) Show SMILES Cn1nccc1Nc1nccc(n1)-c1ccn([C@H](CO)c2ccc(Cl)c(F)c2)c(=O)c1 |r| Show InChI InChI=1S/C21H18ClFN6O2/c1-28-19(5-8-25-28)27-21-24-7-4-17(26-21)13-6-9-29(20(31)11-13)18(12-30)14-2-3-15(22)16(23)10-14/h2-11,18,30H,12H2,1H3,(H,24,26,27)/t18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	PDB US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM50094465 (CHEMBL3590106 | US10525036, Example BVD-523 | US10...) Show SMILES CC(C)Nc1cc(-c2c[nH]c(c2)C(=O)N[C@H](CO)c2cccc(Cl)c2)c(Cl)cn1 |r| Show InChI InChI=1S/C19H21NO3/c21-18(23-17-11-13-20-14-12-17)19(22,15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-10,17,20,22H,11-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50094465 (CHEMBL3590106 | US10525036, Example BVD-523 | US10...) Show SMILES CC(C)Nc1cc(-c2c[nH]c(c2)C(=O)N[C@H](CO)c2cccc(Cl)c2)c(Cl)cn1 |r| Show InChI InChI=1S/C19H21NO3/c21-18(23-17-11-13-20-14-12-17)19(22,15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-10,17,20,22H,11-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES O=C(CN1CC[C@H](C1)C(=O)Nc1ccc2[nH]nc(-c3ccncc3)c2c1)N1CCN(CC1)c1ccc(cc1)-c1ncccn1 |r| Show InChI InChI=1S/C22H27NO3/c1-2-15-23-16-13-20(14-17-23)26-21(24)22(25,18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-12,20,25H,2,13-17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES O=C(CN1CC[C@H](C1)C(=O)Nc1ccc2[nH]nc(-c3ccncc3)c2c1)N1CCN(CC1)c1ccc(cc1)-c1ncccn1 |r| Show InChI InChI=1S/C22H27NO3/c1-2-15-23-16-13-20(14-17-23)26-21(24)22(25,18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-12,20,25H,2,13-17H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421838 (2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-yl)-7...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CCC2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |c:35| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421838 (2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-yl)-7...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CCC2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |c:35| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421840 (2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-yl)-7...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CCC2(CCN(CC(=O)N3CCN(CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421840 (2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-yl)-7...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CCC2(CCN(CC(=O)N3CCN(CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421843 (7-(2-(4-(4-(1-Methyl-1H-1,2,4-triazol-3-yl)phenyl)...) Show SMILES Cc1cc(ccn1)-c1n[nH]c2ccc(cc12)N1CCC2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |c:32| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421843 (7-(2-(4-(4-(1-Methyl-1H-1,2,4-triazol-3-yl)phenyl)...) Show SMILES Cc1cc(ccn1)-c1n[nH]c2ccc(cc12)N1CCC2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |c:32| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421844 (7-(2-(4-(4-(1-Methyl-1H-1,2,4-triazol-3-yl)phenyl)...) Show SMILES Cc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CCC2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |c:32| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421844 (7-(2-(4-(4-(1-Methyl-1H-1,2,4-triazol-3-yl)phenyl)...) Show SMILES Cc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CCC2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |c:32| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421845 ((S)-7-(2-(4-(4-(1-Methyl-1H-1,2,4-triazol-3-yl)phe...) Show SMILES Cc1cc(ccn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |r,c:32| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421845 ((S)-7-(2-(4-(4-(1-Methyl-1H-1,2,4-triazol-3-yl)phe...) Show SMILES Cc1cc(ccn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |r,c:32| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421846 ((R)-7-(2-(4-(4-(1-Methyl-1H-1,2,4-triazol-3-yl)phe...) Show SMILES Cc1cc(ccn1)-c1n[nH]c2ccc(cc12)N1CC[C@@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |r,c:32| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM426336 ((S)-2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |r,c:35| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM426336 ((S)-2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |r,c:35| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421849 ((5S)-7-(2-(4-(4-(1-Methyl-1H-1,2,4-triazol-3-yl)ph...) Show SMILES Cn1cnc(n1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(C4CCNC(C4)C(F)(F)F)c3c2)C1 |r,t:14| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421849 ((5S)-7-(2-(4-(4-(1-Methyl-1H-1,2,4-triazol-3-yl)ph...) Show SMILES Cn1cnc(n1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(C4CCNC(C4)C(F)(F)F)c3c2)C1 |r,t:14| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421851 ((S)-7-(2-(4-(4-(1H-1,2,3-Triazol-1-yl)phenyl)-3,6-...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-n3ccnn3)C2)C1=O |r,c:35| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421851 ((S)-7-(2-(4-(4-(1H-1,2,3-Triazol-1-yl)phenyl)-3,6-...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-n3ccnn3)C2)C1=O |r,c:35| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421852 ((S)-2-(3-(6-isopropoxypyridin-3-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3cn(C)nn3)C2)C1=O |r,c:35| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421852 ((S)-2-(3-(6-isopropoxypyridin-3-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3cn(C)nn3)C2)C1=O |r,c:35| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421853 ((S)-2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421853 ((S)-2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421854 ((S)-2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3nnc(C)o3)C2)C1=O |r,c:35| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421854 ((S)-2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3nnc(C)o3)C2)C1=O |r,c:35| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421855 ((S)-7-(2-(4-(4-(5-(Ethylamino)-1,3,4-oxadiazol-2-y...) Show SMILES CCNc1nnc(o1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(-c4ccc(OC(C)C)nc4)c3c2)C1 |r,t:16| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421855 ((S)-7-(2-(4-(4-(5-(Ethylamino)-1,3,4-oxadiazol-2-y...) Show SMILES CCNc1nnc(o1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(-c4ccc(OC(C)C)nc4)c3c2)C1 |r,t:16| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421856 ((S)-7-(2-(4-(4-(5-(Ethylamino)-1,3,4-thiadiazol-2-...) Show SMILES CCNc1nnc(s1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(-c4ccc(OC(C)C)nc4)c3c2)C1 |r,t:16| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421856 ((S)-7-(2-(4-(4-(5-(Ethylamino)-1,3,4-thiadiazol-2-...) Show SMILES CCNc1nnc(s1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(-c4ccc(OC(C)C)nc4)c3c2)C1 |r,t:16| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421857 ((S)-7-(2-(4-(4-(1-Methyl-1H-1,2,4-triazol-3-yl)phe...) Show SMILES Cn1cnc(n1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(-c4ccnc(c4)C(F)(F)F)c3c2)C1 |r,t:14| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421857 ((S)-7-(2-(4-(4-(1-Methyl-1H-1,2,4-triazol-3-yl)phe...) Show SMILES Cn1cnc(n1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(-c4ccnc(c4)C(F)(F)F)c3c2)C1 |r,t:14| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421859 ((S)-2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncccn3)C2)C1=O |r,c:35| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421860 ((S)-7-(2-(4-(4-(5-Fluoropyrimidin-2-yl)phenyl)-3,6...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncc(F)cn3)C2)C1=O |r,c:35| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421860 ((S)-7-(2-(4-(4-(5-Fluoropyrimidin-2-yl)phenyl)-3,6...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncc(F)cn3)C2)C1=O |r,c:35| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421861 ((S)-2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(CC3)C34CC(C3)(C4)c3ncn(C)n3)C2)C1=O |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421863 ((S)-2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3cn(C)cn3)C2)C1=O |r,c:35| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421865 ((S)-7-(2-(4-(4-(5-Fluoropyrimidin-2-yl)phenyl)-3,6...) Show SMILES Fc1cnc(nc1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(-c4ccnc(c4)C(F)(F)F)c3c2)C1 |r,t:15| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421865 ((S)-7-(2-(4-(4-(5-Fluoropyrimidin-2-yl)phenyl)-3,6...) Show SMILES Fc1cnc(nc1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(-c4ccnc(c4)C(F)(F)F)c3c2)C1 |r,t:15| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421866 ((S)-2-(3-(4-Fluorophenyl)-1H-indazol-5-yl)-7-(2-(4...) Show SMILES Cn1cnc(n1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(-c4ccc(F)cc4)c3c2)C1 |r,t:14| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421866 ((S)-2-(3-(4-Fluorophenyl)-1H-indazol-5-yl)-7-(2-(4...) Show SMILES Cn1cnc(n1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(-c4ccc(F)cc4)c3c2)C1 |r,t:14| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421867 ((S)-2-(3-(2-Isopropoxypyridin-4-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1cc(ccn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |r,c:35| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421867 ((S)-2-(3-(2-Isopropoxypyridin-4-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1cc(ccn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |r,c:35| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421868 ((S)-2-(3-(3-Fluoropyridin-4-yl)-1H-indazol-5-yl)-7...) Show SMILES Cn1cnc(n1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(-c4ccncc4F)c3c2)C1 |r,t:14| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421868 ((S)-2-(3-(3-Fluoropyridin-4-yl)-1H-indazol-5-yl)-7...) Show SMILES Cn1cnc(n1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(-c4ccncc4F)c3c2)C1 |r,t:14| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421869 ((S)-2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCN(CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421870 ((S)-7-(2-(4-(4-(1-Methyl-1H-1,2,4-triazol-3-yl)phe...) Show SMILES Cn1cnc(n1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(N4CCOCC4)c3c2)C1 |r,t:14| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10525036 (2020) BindingDB Entry DOI: 10.7270/Q26Q20N0
					More data for this Ligand-Target Pair

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