Compile Data Set for Download or QSAR

Found 215 hits Enz. Inhib. hit(s) with all data for entry = 9035   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384444 (US10590114, No. 130 | US11111235, No. 130 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C(=O)N(C)C)ncc1C(F)(F)F Show InChI InChI=1S/C16H20F3N7O/c1-4-20-13-10(16(17,18)19)8-21-15(23-13)22-12-7-11(14(27)25(2)3)24-26(12)9-5-6-9/h7-9H,4-6H2,1-3H3,(H2,20,21,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384445 (US10590114, No. 131 | US11111235, Compound 131 | U...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C(C)(C)C#N)ncc1C(F)(F)F Show InChI InChI=1S/C17H20F3N7/c1-4-22-14-11(17(18,19)20)8-23-15(25-14)24-13-7-12(16(2,3)9-21)26-27(13)10-5-6-10/h7-8,10H,4-6H2,1-3H3,(H2,22,23,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384446 (US10590114, No. 132 | US11111235, No. 132 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)S(C)(=O)=O)ncc1C(F)(F)F Show InChI InChI=1S/C14H17F3N6O2S/c1-3-18-12-9(14(15,16)17)7-19-13(21-12)20-10-6-11(26(2,24)25)22-23(10)8-4-5-8/h6-8H,3-5H2,1-2H3,(H2,18,19,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384448 (US10590114, No. 134 | US11111235, No. 134 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C(C)(C)O)ncc1C(F)(F)F Show InChI InChI=1S/C16H21F3N6O/c1-4-20-13-10(16(17,18)19)8-21-14(23-13)22-12-7-11(15(2,3)26)24-25(12)9-5-6-9/h7-9,26H,4-6H2,1-3H3,(H2,20,21,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384451 (US10590114, No. 138 | US11111235, No. 138 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C(C)n2nccn2)ncc1C(F)(F)F Show InChI InChI=1S/C17H20F3N9/c1-3-21-15-12(17(18,19)20)9-22-16(26-15)25-14-8-13(27-28(14)11-4-5-11)10(2)29-23-6-7-24-29/h6-11H,3-5H2,1-2H3,(H2,21,22,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384451 (US10590114, No. 138 | US11111235, No. 138 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C(C)n2nccn2)ncc1C(F)(F)F Show InChI InChI=1S/C17H20F3N9/c1-3-21-15-12(17(18,19)20)9-22-16(26-15)25-14-8-13(27-28(14)11-4-5-11)10(2)29-23-6-7-24-29/h6-11H,3-5H2,1-2H3,(H2,21,22,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384453 (US10590114, No. 139 | US11111235, No. 139 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C(C)(C)S(C)(=O)=O)ncc1C(F)(F)F Show InChI InChI=1S/C17H23F3N6O2S/c1-5-21-14-11(17(18,19)20)9-22-15(24-14)23-13-8-12(16(2,3)29(4,27)28)25-26(13)10-6-7-10/h8-10H,5-7H2,1-4H3,(H2,21,22,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384454 (US10590114, No. 140 | US11111235, No. 140 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C(C)(C)S(C)(=O)=O)ncc1Br Show InChI InChI=1S/C16H23BrN6O2S/c1-5-18-14-11(17)9-19-15(21-14)20-13-8-12(16(2,3)26(4,24)25)22-23(13)10-6-7-10/h8-10H,5-7H2,1-4H3,(H2,18,19,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384455 (US10590114, No. 141 | US11111235, Compound 141 | U...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C(C)(C)C#N)ncc1Br Show InChI InChI=1S/C16H20BrN7/c1-4-19-14-11(17)8-20-15(22-14)21-13-7-12(16(2,3)9-18)23-24(13)10-5-6-10/h7-8,10H,4-6H2,1-3H3,(H2,19,20,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384456 (US10590114, No. 142 | US11111235, No. 142 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)-c2ncoc2C)ncc1C(F)(F)F Show InChI InChI=1S/C17H18F3N7O/c1-3-21-15-11(17(18,19)20)7-22-16(25-15)24-13-6-12(14-9(2)28-8-23-14)26-27(13)10-4-5-10/h6-8,10H,3-5H2,1-2H3,(H2,21,22,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384457 (US10590114, No. 144 | US11111235, Compound 143 | U...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C2(C)CCOC2=O)ncc1C(F)(F)F Show InChI InChI=1S/C18H21F3N6O2/c1-3-22-14-11(18(19,20)21)9-23-16(25-14)24-13-8-12(26-27(13)10-4-5-10)17(2)6-7-29-15(17)28/h8-10H,3-7H2,1-2H3,(H2,22,23,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384457 (US10590114, No. 144 | US11111235, Compound 143 | U...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C2(C)CCOC2=O)ncc1C(F)(F)F Show InChI InChI=1S/C18H21F3N6O2/c1-3-22-14-11(18(19,20)21)9-23-16(25-14)24-13-8-12(26-27(13)10-4-5-10)17(2)6-7-29-15(17)28/h8-10H,3-7H2,1-2H3,(H2,22,23,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384459 (US10590114, No. 145 | US11111235, No. 145 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C2(C)COC2)ncc1C(F)(F)F Show InChI InChI=1S/C17H21F3N6O/c1-3-21-14-11(17(18,19)20)7-22-15(24-14)23-13-6-12(16(2)8-27-9-16)25-26(13)10-4-5-10/h6-7,10H,3-5,8-9H2,1-2H3,(H2,21,22,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384460 (US10590114, No. 147 | US11111235, No. 147 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C(C)n2nccn2)ncc1Br Show InChI InChI=1S/C16H20BrN9/c1-3-18-15-12(17)9-19-16(23-15)22-14-8-13(24-25(14)11-4-5-11)10(2)26-20-6-7-21-26/h6-11H,3-5H2,1-2H3,(H2,18,19,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384460 (US10590114, No. 147 | US11111235, No. 147 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C(C)n2nccn2)ncc1Br Show InChI InChI=1S/C16H20BrN9/c1-3-18-15-12(17)9-19-16(23-15)22-14-8-13(24-25(14)11-4-5-11)10(2)26-20-6-7-21-26/h6-11H,3-5H2,1-2H3,(H2,18,19,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384462 (US10590114, No. 148 | US11111235, No. 148 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C2(C)COC2)ncc1Br Show InChI InChI=1S/C16H21BrN6O/c1-3-18-14-11(17)7-19-15(21-14)20-13-6-12(16(2)8-24-9-16)22-23(13)10-4-5-10/h6-7,10H,3-5,8-9H2,1-2H3,(H2,18,19,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384464 (US10590114, No. 151 | US11111235, Compound 150 | U...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C2(C)CCOC2=O)ncc1Br Show InChI InChI=1S/C17H21BrN6O2/c1-3-19-14-11(18)9-20-16(22-14)21-13-8-12(23-24(13)10-4-5-10)17(2)6-7-26-15(17)25/h8-10H,3-7H2,1-2H3,(H2,19,20,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384464 (US10590114, No. 151 | US11111235, Compound 150 | U...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C2(C)CCOC2=O)ncc1Br Show InChI InChI=1S/C17H21BrN6O2/c1-3-19-14-11(18)9-20-16(22-14)21-13-8-12(23-24(13)10-4-5-10)17(2)6-7-26-15(17)25/h8-10H,3-7H2,1-2H3,(H2,19,20,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384466 (US10590114, No. 152 | US11111235, No. 152 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)[C@H]2C[C@@H]2C#N)ncc1C(F)(F)F |r| Show InChI InChI=1S/C17H18F3N7/c1-2-22-15-12(17(18,19)20)8-23-16(25-15)24-14-6-13(11-5-9(11)7-21)26-27(14)10-3-4-10/h6,8-11H,2-5H2,1H3,(H2,22,23,24,25)/t9-,11+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384467 (US10590114, No. 153 | US11111235, No. 153 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)N2CCCC2=O)ncc1C(F)(F)F Show InChI InChI=1S/C17H20F3N7O/c1-2-21-15-11(17(18,19)20)9-22-16(24-15)23-12-8-13(25-27(12)10-5-6-10)26-7-3-4-14(26)28/h8-10H,2-7H2,1H3,(H2,21,22,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384468 (US10590114, No. 154 | US11111235, No. 154 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)N2CCCS2(=O)=O)ncc1C(F)(F)F Show InChI InChI=1S/C16H20F3N7O2S/c1-2-20-14-11(16(17,18)19)9-21-15(23-14)22-12-8-13(24-26(12)10-4-5-10)25-6-3-7-29(25,27)28/h8-10H,2-7H2,1H3,(H2,20,21,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384469 (US10590114, No. 156 | US11111235, Compound 155 | U...) Show SMILES CNc1nc(Nc2cc(nn2C2CC2)C2(C)CCOC2=O)ncc1C(F)(F)F Show InChI InChI=1S/C17H19F3N6O2/c1-16(5-6-28-14(16)27)11-7-12(26(25-11)9-3-4-9)23-15-22-8-10(17(18,19)20)13(21-2)24-15/h7-9H,3-6H2,1-2H3,(H2,21,22,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384469 (US10590114, No. 156 | US11111235, Compound 155 | U...) Show SMILES CNc1nc(Nc2cc(nn2C2CC2)C2(C)CCOC2=O)ncc1C(F)(F)F Show InChI InChI=1S/C17H19F3N6O2/c1-16(5-6-28-14(16)27)11-7-12(26(25-11)9-3-4-9)23-15-22-8-10(17(18,19)20)13(21-2)24-15/h7-9H,3-6H2,1-2H3,(H2,21,22,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384472 (US10590114, No. 158 | US11111235, No. 158 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)N2CCCC2=O)ncc1Br Show InChI InChI=1S/C16H20BrN7O/c1-2-18-15-11(17)9-19-16(21-15)20-12-8-13(22-24(12)10-5-6-10)23-7-3-4-14(23)25/h8-10H,2-7H2,1H3,(H2,18,19,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384473 (US10590114, No. 159 | US11111235, No. 159 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)N2CCCS2(=O)=O)ncc1Br Show InChI InChI=1S/C15H20BrN7O2S/c1-2-17-14-11(16)9-18-15(20-14)19-12-8-13(21-23(12)10-4-5-10)22-6-3-7-26(22,24)25/h8-10H,2-7H2,1H3,(H2,17,18,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384474 (US10590114, No. 161 | US11111235, No. 161 | US1159...) Show SMILES COc1nc(Nc2cc(nn2C2CC2)C2(C)CCOC2=O)ncc1C(F)(F)F Show InChI InChI=1S/C17H18F3N5O3/c1-16(5-6-28-14(16)26)11-7-12(25(24-11)9-3-4-9)22-15-21-8-10(17(18,19)20)13(23-15)27-2/h7-9H,3-6H2,1-2H3,(H,21,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384476 (US10590114, No. 162 | US11111235, No. 162 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)[C@@]23C[C@@H]2COC3=O)ncc1C(F)(F)F |r| Show InChI InChI=1S/C18H19F3N6O2/c1-2-22-14-11(18(19,20)21)7-23-16(25-14)24-13-5-12(26-27(13)10-3-4-10)17-6-9(17)8-29-15(17)28/h5,7,9-10H,2-4,6,8H2,1H3,(H2,22,23,24,25)/t9-,17-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384477 (US10590114, No. 163 | US11111235, No. 163 | US1159...) Show SMILES CNc1nc(Nc2cc(nn2C2CC2)[C@@]23C[C@@H]2COC3=O)ncc1C(F)(F)F |r| Show InChI InChI=1S/C17H17F3N6O2/c1-21-13-10(17(18,19)20)6-22-15(24-13)23-12-4-11(25-26(12)9-2-3-9)16-5-8(16)7-28-14(16)27/h4,6,8-9H,2-3,5,7H2,1H3,(H2,21,22,23,24)/t8-,16-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384478 (US10590114, No. 164 | US11111235, No. 164 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)[C@H]2C[C@H]2C#N)ncc1C(F)(F)F |r| Show InChI InChI=1S/C17H18F3N7/c1-2-22-15-12(17(18,19)20)8-23-16(25-15)24-14-6-13(11-5-9(11)7-21)26-27(14)10-3-4-10/h6,8-11H,2-5H2,1H3,(H2,22,23,24,25)/t9-,11-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384479 (US10590114, No. 165 | US11111235, No. 165 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)[C@]23C[C@H]2COC3=O)ncc1C(F)(F)F |r| Show InChI InChI=1S/C18H19F3N6O2/c1-2-22-14-11(18(19,20)21)7-23-16(25-14)24-13-5-12(26-27(13)10-3-4-10)17-6-9(17)8-29-15(17)28/h5,7,9-10H,2-4,6,8H2,1H3,(H2,22,23,24,25)/t9-,17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384480 (US10590114, No. 167 | US11111235, No. 167 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C2(C)CCn3ccnc23)ncc1C(F)(F)F Show InChI InChI=1S/C20H23F3N8/c1-3-24-16-13(20(21,22)23)11-26-18(28-16)27-15-10-14(29-31(15)12-4-5-12)19(2)6-8-30-9-7-25-17(19)30/h7,9-12H,3-6,8H2,1-2H3,(H2,24,26,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384482 (US10590114, No. 168 | US11591316, Compound 168 | U...) Show SMILES CNc1nc(Nc2cc(nn2C2CC2)[C@]23C[C@H]2COC3=O)ncc1C(F)(F)F |r| Show InChI InChI=1S/C17H17F3N6O2/c1-21-13-10(17(18,19)20)6-22-15(24-13)23-12-4-11(25-26(12)9-2-3-9)16-5-8(16)7-28-14(16)27/h4,6,8-9H,2-3,5,7H2,1H3,(H2,21,22,23,24)/t8-,16-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384483 (US10590114, No. 169 | US11111235, No. 169 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)[C@H]2C[C@H]2C(=O)OCC)ncc1C(F)(F)F |r| Show InChI InChI=1S/C19H23F3N6O2/c1-3-23-16-13(19(20,21)22)9-24-18(26-16)25-15-8-14(27-28(15)10-5-6-10)11-7-12(11)17(29)30-4-2/h8-12H,3-7H2,1-2H3,(H2,23,24,25,26)/t11-,12+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384484 (US10590114, No. 170 | US11111235, No. 170 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)[C@H]2C[C@H]2C(N)=O)ncc1C(F)(F)F |r| Show InChI InChI=1S/C17H20F3N7O/c1-2-22-15-11(17(18,19)20)7-23-16(25-15)24-13-6-12(9-5-10(9)14(21)28)26-27(13)8-3-4-8/h6-10H,2-5H2,1H3,(H2,21,28)(H2,22,23,24,25)/t9-,10+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384485 (US10590114, No. 172 | US11111235, Compound 172 | U...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C2(C)CCn3ncnc23)ncc1C(F)(F)F Show InChI InChI=1S/C19H22F3N9/c1-3-23-15-12(19(20,21)22)9-24-17(28-15)27-14-8-13(29-31(14)11-4-5-11)18(2)6-7-30-16(18)25-10-26-30/h8-11H,3-7H2,1-2H3,(H2,23,24,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384487 (US10590114, No. 174 | US11111235, No. 174 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C)C2(C)CCOC2=O)ncc1C(F)(F)F Show InChI InChI=1S/C16H19F3N6O2/c1-4-20-12-9(16(17,18)19)8-21-14(23-12)22-11-7-10(24-25(11)3)15(2)5-6-27-13(15)26/h7-8H,4-6H2,1-3H3,(H2,20,21,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384487 (US10590114, No. 174 | US11111235, No. 174 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C)C2(C)CCOC2=O)ncc1C(F)(F)F Show InChI InChI=1S/C16H19F3N6O2/c1-4-20-12-9(16(17,18)19)8-21-14(23-12)22-11-7-10(24-25(11)3)15(2)5-6-27-13(15)26/h7-8H,4-6H2,1-3H3,(H2,20,21,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384489 (US10590114, No. 176 | US11111235, No. 176 | US1159...) Show SMILES CNc1nc(Nc2cc(nn2C)C2(C)CCOC2=O)ncc1C(F)(F)F Show InChI InChI=1S/C15H17F3N6O2/c1-14(4-5-26-12(14)25)9-6-10(24(3)23-9)21-13-20-7-8(15(16,17)18)11(19-2)22-13/h6-7H,4-5H2,1-3H3,(H2,19,20,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384489 (US10590114, No. 176 | US11111235, No. 176 | US1159...) Show SMILES CNc1nc(Nc2cc(nn2C)C2(C)CCOC2=O)ncc1C(F)(F)F Show InChI InChI=1S/C15H17F3N6O2/c1-14(4-5-26-12(14)25)9-6-10(24(3)23-9)21-13-20-7-8(15(16,17)18)11(19-2)22-13/h6-7H,4-5H2,1-3H3,(H2,19,20,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM436382 (US10590114, No. 177 | US10590114, No. 178) Show SMILES CNc1nc(Nc2cc(nn2C)C2(C)CCn3ccnc23)ncc1C(F)(F)F Show InChI InChI=1S/C17H19F3N8/c1-16(4-6-28-7-5-22-14(16)28)11-8-12(27(3)26-11)24-15-23-9-10(17(18,19)20)13(21-2)25-15/h5,7-9H,4,6H2,1-3H3,(H2,21,23,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384493 (US10590114, No. 179 | US11111235, No. 179 | US1159...) Show SMILES CCNc1nc(Nc2ccnn2[C@@H]2C[C@H](O)C2)ncc1C(F)(F)F |r,wU:12.12,14.15,(6.5,-2.67,;5.16,-1.9,;5.16,-.36,;3.83,.41,;2.5,-.36,;1.16,.41,;-.17,-.36,;-.17,-1.9,;1.07,-2.8,;.6,-4.26,;-.94,-4.26,;-1.42,-2.8,;-2.91,-2.4,;-3.68,-1.07,;-5.01,-1.84,;-6.5,-1.44,;-4.24,-3.17,;1.16,1.95,;2.5,2.72,;3.83,1.95,;5.16,2.72,;5.16,4.26,;6.5,1.95,;6.5,3.49,)| Show InChI InChI=1S/C14H17F3N6O/c1-2-18-12-10(14(15,16)17)7-19-13(22-12)21-11-3-4-20-23(11)8-5-9(24)6-8/h3-4,7-9,24H,2,5-6H2,1H3,(H2,18,19,21,22)/t8-,9+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384495 (US10590114, No. 181 | US11111235, No. 181 | US1159...) Show SMILES CCNc1nc(Nc2ccnn2[C@H]2C[C@@H](C2)C#N)ncc1C(F)(F)F |r,wU:12.12,wD:14.17,(7.24,-2.67,;5.91,-1.9,;5.91,-.36,;4.57,.41,;3.24,-.36,;1.91,.41,;.57,-.36,;.57,-1.9,;1.82,-2.8,;1.34,-4.26,;-.2,-4.26,;-.67,-2.8,;-2.16,-2.4,;-3.5,-3.17,;-4.27,-1.84,;-2.93,-1.07,;-5.75,-1.44,;-7.24,-1.04,;1.91,1.95,;3.24,2.72,;4.57,1.95,;5.91,2.72,;5.91,4.26,;7.24,1.95,;7.24,3.49,)| Show InChI InChI=1S/C15H16F3N7/c1-2-20-13-11(15(16,17)18)8-21-14(24-13)23-12-3-4-22-25(12)10-5-9(6-10)7-19/h3-4,8-10H,2,5-6H2,1H3,(H2,20,21,23,24)/t9-,10-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384496 (US10590114, No. 182 | US11111235, No. 182 | US1159...) Show SMILES CCNc1nc(Nc2ccnn2[C@H]2C[C@@H](C2)n2nccn2)ncc1C(F)(F)F |r,wU:12.12,wD:14.17,(7.74,-2.67,;6.41,-1.9,;6.41,-.36,;5.08,.41,;3.74,-.36,;2.41,.41,;1.07,-.36,;1.07,-1.9,;2.32,-2.8,;1.84,-4.26,;.3,-4.26,;-.17,-2.8,;-1.66,-2.4,;-2.99,-3.17,;-3.76,-1.84,;-2.43,-1.07,;-5.25,-1.44,;-5.73,.03,;-7.27,.03,;-7.74,-1.44,;-6.5,-2.34,;2.41,1.95,;3.74,2.72,;5.08,1.95,;6.41,2.72,;6.41,4.26,;7.74,1.95,;7.74,3.49,)| Show InChI InChI=1S/C16H18F3N9/c1-2-20-14-12(16(17,18)19)9-21-15(26-14)25-13-3-4-22-27(13)10-7-11(8-10)28-23-5-6-24-28/h3-6,9-11H,2,7-8H2,1H3,(H2,20,21,25,26)/t10-,11-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384497 (US10590114, No. 183 | US11111235, No. 183 | US1159...) Show SMILES CCNc1nc(Nc2ccnn2[C@H]2C[C@@H](C2)n2ccnn2)ncc1C(F)(F)F |r,wU:12.12,wD:14.17,(7.74,-2.67,;6.41,-1.9,;6.41,-.36,;5.08,.41,;3.74,-.36,;2.41,.41,;1.07,-.36,;1.07,-1.9,;2.32,-2.8,;1.84,-4.26,;.3,-4.26,;-.17,-2.8,;-1.66,-2.4,;-2.99,-3.17,;-3.76,-1.84,;-2.43,-1.07,;-5.25,-1.44,;-5.73,.03,;-7.27,.03,;-7.74,-1.44,;-6.5,-2.34,;2.41,1.95,;3.74,2.72,;5.08,1.95,;6.41,2.72,;6.41,4.26,;7.74,1.95,;7.74,3.49,)| Show InChI InChI=1S/C16H18F3N9/c1-2-20-14-12(16(17,18)19)9-21-15(25-14)24-13-3-4-23-28(13)11-7-10(8-11)27-6-5-22-26-27/h3-6,9-11H,2,7-8H2,1H3,(H2,20,21,24,25)/t10-,11-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384498 (US10590114, No. 184 | US11591316, Compound 184 | U...) Show SMILES CCNc1nc(Nc2cc(nn2C)[C@@]23C[C@@H]2COC3=O)ncc1C(F)(F)F |r| Show InChI InChI=1S/C16H17F3N6O2/c1-3-20-12-9(16(17,18)19)6-21-14(23-12)22-11-4-10(24-25(11)2)15-5-8(15)7-27-13(15)26/h4,6,8H,3,5,7H2,1-2H3,(H2,20,21,22,23)/t8-,15-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384499 (US10590114, No. 185 | US11111235, No. 185 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C)[C@]23C[C@H]2COC3=O)ncc1C(F)(F)F |r| Show InChI InChI=1S/C16H17F3N6O2/c1-3-20-12-9(16(17,18)19)6-21-14(23-12)22-11-4-10(24-25(11)2)15-5-8(15)7-27-13(15)26/h4,6,8H,3,5,7H2,1-2H3,(H2,20,21,22,23)/t8-,15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384500 (US10590114, No. 187 | US11111235, No. 187 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C)C2(C)CCCO2)ncc1C(F)(F)F Show InChI InChI=1S/C16H21F3N6O/c1-4-20-13-10(16(17,18)19)9-21-14(23-13)22-12-8-11(24-25(12)3)15(2)6-5-7-26-15/h8-9H,4-7H2,1-3H3,(H2,20,21,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384500 (US10590114, No. 187 | US11111235, No. 187 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C)C2(C)CCCO2)ncc1C(F)(F)F Show InChI InChI=1S/C16H21F3N6O/c1-4-20-13-10(16(17,18)19)9-21-14(23-13)22-12-8-11(24-25(12)3)15(2)6-5-7-26-15/h8-9H,4-7H2,1-3H3,(H2,20,21,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384504 (US10590114, No. 190 | US11111235, No. 190 | US1159...) Show SMILES CCNc1nc(Nc2ccnn2[C@H]2C[C@H](F)C2)ncc1C(F)(F)F |r,wU:12.12,wD:14.15,(6.5,-2.67,;5.16,-1.9,;5.16,-.36,;3.83,.41,;2.5,-.36,;1.16,.41,;-.17,-.36,;-.17,-1.9,;1.07,-2.8,;.6,-4.26,;-.94,-4.26,;-1.42,-2.8,;-2.91,-2.4,;-4.24,-3.17,;-5.01,-1.84,;-6.5,-1.44,;-3.68,-1.07,;1.16,1.95,;2.5,2.72,;3.83,1.95,;5.16,2.72,;5.16,4.26,;6.5,1.95,;6.5,3.49,)| Show InChI InChI=1S/C14H16F4N6/c1-2-19-12-10(14(16,17)18)7-20-13(23-12)22-11-3-4-21-24(11)9-5-8(15)6-9/h3-4,7-9H,2,5-6H2,1H3,(H2,19,20,22,23)/t8-,9-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384505 (US10590114, No. 191 | US11111235, No. 191 | US1159...) Show SMILES CCNc1nc(Nc2cc(nn2C2CCC2)C(C)(C)O)ncc1C(F)(F)F Show InChI InChI=1S/C17H23F3N6O/c1-4-21-14-11(17(18,19)20)9-22-15(24-14)23-13-8-12(16(2,3)27)25-26(13)10-6-5-7-10/h8-10,27H,4-7H2,1-3H3,(H2,21,22,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair

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