Compile Data Set for Download or QSAR

Found 11 hits Enz. Inhib. hit(s) with all data for entry = 9076   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM439129 ((R)-5-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl...) Show SMILES C[C@H](C1CCN(CC(C)(C)C)CC1)c1sc2CCCN(Cc3c(C)cc(C)[nH]c3=O)C(=O)c2c1C |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED US Patent					Assay Description 1. Prepare 10 mM stock of compounds from solid in 100% DMSO.2. Set up an 11-point serial dilution (1:4 dilution, top concentration 10 mM) in 100% DMS...				US Patent US10604531 (2020) BindingDB Entry DOI: 10.7270/Q23X89N4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM439130 ((R)-2-(1-(1-(Cyclobutylmethyl)piperidin-4-yl)ethyl...) Show SMILES C[C@H](C1CCN(CC2CCC2)CC1)c1sc2CCCN(Cc3c(C)cc(C)[nH]c3=O)C(=O)c2c1C |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED US Patent					Assay Description 1. Prepare 10 mM stock of compounds from solid in 100% DMSO.2. Set up an 11-point serial dilution (1:4 dilution, top concentration 10 mM) in 100% DMS...				US Patent US10604531 (2020) BindingDB Entry DOI: 10.7270/Q23X89N4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM439132 ((R)-5-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl...) Show SMILES CC(C)CN1CCC(CC1)[C@@H](C)c1sc2CCCN(Cc3c(C)cc(C)[nH]c3=O)C(=O)c2c1C |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED US Patent					Assay Description 1. Prepare 10 mM stock of compounds from solid in 100% DMSO.2. Set up an 11-point serial dilution (1:4 dilution, top concentration 10 mM) in 100% DMS...				US Patent US10604531 (2020) BindingDB Entry DOI: 10.7270/Q23X89N4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM439133 ((R)-2-(1-(1-(Cyclopentylmethyl)piperidin-4-yl)ethy...) Show SMILES C[C@H](C1CCN(CC2CCCC2)CC1)c1sc2CCCN(Cc3c(C)cc(C)[nH]c3=O)C(=O)c2c1C |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED US Patent					Assay Description 1. Prepare 10 mM stock of compounds from solid in 100% DMSO.2. Set up an 11-point serial dilution (1:4 dilution, top concentration 10 mM) in 100% DMS...				US Patent US10604531 (2020) BindingDB Entry DOI: 10.7270/Q23X89N4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM439163 ((R)-5-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl...) Show SMILES CCC(C)(C)CN1CCC(CC1)[C@@H](C)c1sc2CCCN(Cc3c(C)cc(C)[nH]c3=O)C(=O)c2c1C |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED US Patent					Assay Description 1. Prepare 10 mM stock of compounds from solid in 100% DMSO.2. Set up an 11-point serial dilution (1:4 dilution, top concentration 10 mM) in 100% DMS...				US Patent US10604531 (2020) BindingDB Entry DOI: 10.7270/Q23X89N4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM439197 ((R)-5-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl...) Show SMILES C[C@H](C1CCN(CC2(C)CC2)CC1)c1sc2CCCN(Cc3c(C)cc(C)[nH]c3=O)C(=O)c2c1C |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED US Patent					Assay Description 1. Prepare 10 mM stock of compounds from solid in 100% DMSO.2. Set up an 11-point serial dilution (1:4 dilution, top concentration 10 mM) in 100% DMS...				US Patent US10604531 (2020) BindingDB Entry DOI: 10.7270/Q23X89N4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM439165 ((R)-2-(1-(1-(Cyclopropylmethyl)piperidin-4-yl)ethy...) Show SMILES C[C@H](C1CCN(CC2CC2)CC1)c1sc2CCCN(Cc3c(C)cc(C)[nH]c3=O)C(=O)c2c1C |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED US Patent					Assay Description 1. Prepare 10 mM stock of compounds from solid in 100% DMSO.2. Set up an 11-point serial dilution (1:4 dilution, top concentration 10 mM) in 100% DMS...				US Patent US10604531 (2020) BindingDB Entry DOI: 10.7270/Q23X89N4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM439169 ((R)-5-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl...) Show SMILES C[C@H](C1CCN(CC2(C)CCCC2)CC1)c1sc2CCCN(Cc3c(C)cc(C)[nH]c3=O)C(=O)c2c1C |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED US Patent					Assay Description 1. Prepare 10 mM stock of compounds from solid in 100% DMSO.2. Set up an 11-point serial dilution (1:4 dilution, top concentration 10 mM) in 100% DMS...				US Patent US10604531 (2020) BindingDB Entry DOI: 10.7270/Q23X89N4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM439190 ((R)-2-(1-(1-(Bicyclo[2.2.2]octan-1-ylmethyl)piperi...) Show SMILES C[C@H](C1CCN(CC23CCC(CC2)CC3)CC1)c1sc2CCCN(Cc3c(C)cc(C)[nH]c3=O)C(=O)c2c1C |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED US Patent					Assay Description 1. Prepare 10 mM stock of compounds from solid in 100% DMSO.2. Set up an 11-point serial dilution (1:4 dilution, top concentration 10 mM) in 100% DMS...				US Patent US10604531 (2020) BindingDB Entry DOI: 10.7270/Q23X89N4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM439192 ((R)-5-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl...) Show SMILES C[C@H](C1CCN(CC2(C)CCC2)CC1)c1sc2CCCN(Cc3c(C)cc(C)[nH]c3=O)C(=O)c2c1C |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED US Patent					Assay Description 1. Prepare 10 mM stock of compounds from solid in 100% DMSO.2. Set up an 11-point serial dilution (1:4 dilution, top concentration 10 mM) in 100% DMS...				US Patent US10604531 (2020) BindingDB Entry DOI: 10.7270/Q23X89N4
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM439164 ((R)-5-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl...) Show SMILES C[C@H](C1CCN(CC(C)(C)F)CC1)c1sc2CCCN(Cc3c(C)cc(C)[nH]c3=O)C(=O)c2c1C |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED US Patent					Assay Description 1. Prepare 10 mM stock of compounds from solid in 100% DMSO.2. Set up an 11-point serial dilution (1:4 dilution, top concentration 10 mM) in 100% DMS...				US Patent US10604531 (2020) BindingDB Entry DOI: 10.7270/Q23X89N4
					More data for this Ligand-Target Pair