Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human)) | BDBM439129![]() ((R)-5-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED US Patent | Assay Description 1. Prepare 10 mM stock of compounds from solid in 100% DMSO.2. Set up an 11-point serial dilution (1:4 dilution, top concentration 10 mM) in 100% DMS... | US Patent US10604531 (2020) BindingDB Entry DOI: 10.7270/Q23X89N4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human)) | BDBM439130![]() ((R)-2-(1-(1-(Cyclobutylmethyl)piperidin-4-yl)ethyl...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED US Patent | Assay Description 1. Prepare 10 mM stock of compounds from solid in 100% DMSO.2. Set up an 11-point serial dilution (1:4 dilution, top concentration 10 mM) in 100% DMS... | US Patent US10604531 (2020) BindingDB Entry DOI: 10.7270/Q23X89N4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human)) | BDBM439132![]() ((R)-5-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED US Patent | Assay Description 1. Prepare 10 mM stock of compounds from solid in 100% DMSO.2. Set up an 11-point serial dilution (1:4 dilution, top concentration 10 mM) in 100% DMS... | US Patent US10604531 (2020) BindingDB Entry DOI: 10.7270/Q23X89N4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human)) | BDBM439133![]() ((R)-2-(1-(1-(Cyclopentylmethyl)piperidin-4-yl)ethy...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED US Patent | Assay Description 1. Prepare 10 mM stock of compounds from solid in 100% DMSO.2. Set up an 11-point serial dilution (1:4 dilution, top concentration 10 mM) in 100% DMS... | US Patent US10604531 (2020) BindingDB Entry DOI: 10.7270/Q23X89N4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human)) | BDBM439163![]() ((R)-5-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED US Patent | Assay Description 1. Prepare 10 mM stock of compounds from solid in 100% DMSO.2. Set up an 11-point serial dilution (1:4 dilution, top concentration 10 mM) in 100% DMS... | US Patent US10604531 (2020) BindingDB Entry DOI: 10.7270/Q23X89N4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human)) | BDBM439197![]() ((R)-5-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED US Patent | Assay Description 1. Prepare 10 mM stock of compounds from solid in 100% DMSO.2. Set up an 11-point serial dilution (1:4 dilution, top concentration 10 mM) in 100% DMS... | US Patent US10604531 (2020) BindingDB Entry DOI: 10.7270/Q23X89N4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human)) | BDBM439165![]() ((R)-2-(1-(1-(Cyclopropylmethyl)piperidin-4-yl)ethy...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED US Patent | Assay Description 1. Prepare 10 mM stock of compounds from solid in 100% DMSO.2. Set up an 11-point serial dilution (1:4 dilution, top concentration 10 mM) in 100% DMS... | US Patent US10604531 (2020) BindingDB Entry DOI: 10.7270/Q23X89N4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human)) | BDBM439169![]() ((R)-5-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED US Patent | Assay Description 1. Prepare 10 mM stock of compounds from solid in 100% DMSO.2. Set up an 11-point serial dilution (1:4 dilution, top concentration 10 mM) in 100% DMS... | US Patent US10604531 (2020) BindingDB Entry DOI: 10.7270/Q23X89N4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human)) | BDBM439190![]() ((R)-2-(1-(1-(Bicyclo[2.2.2]octan-1-ylmethyl)piperi...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED US Patent | Assay Description 1. Prepare 10 mM stock of compounds from solid in 100% DMSO.2. Set up an 11-point serial dilution (1:4 dilution, top concentration 10 mM) in 100% DMS... | US Patent US10604531 (2020) BindingDB Entry DOI: 10.7270/Q23X89N4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human)) | BDBM439192![]() ((R)-5-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED US Patent | Assay Description 1. Prepare 10 mM stock of compounds from solid in 100% DMSO.2. Set up an 11-point serial dilution (1:4 dilution, top concentration 10 mM) in 100% DMS... | US Patent US10604531 (2020) BindingDB Entry DOI: 10.7270/Q23X89N4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human)) | BDBM439164![]() ((R)-5-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED US Patent | Assay Description 1. Prepare 10 mM stock of compounds from solid in 100% DMSO.2. Set up an 11-point serial dilution (1:4 dilution, top concentration 10 mM) in 100% DMS... | US Patent US10604531 (2020) BindingDB Entry DOI: 10.7270/Q23X89N4 | |||||||||||
More data for this Ligand-Target Pair |